• Title/Summary/Keyword: 다회 사용

Search Result 21, Processing Time 0.026 seconds

Effect of Formalin Fumigation on Rotatory Cocooning Frame during Mounting Period (상족중 회전섶 포르말린훈증 소독효과)

  • Seol, Gwang-Yeol;Yang, Seong-Yeol;Lee, Sang-Pung
    • Journal of Sericultural and Entomological Science
    • /
    • v.33 no.2
    • /
    • pp.97-99
    • /
    • 1991
  • Disinfection of the rotatory cocooning frame is difficult under a multiple rearing system as the work is successively done. Accordingly, to investigate the effect of formalin fumigation on the rotatory cocooning frame during mounting period the mulberry leaves smeared with the water extract of dust collected form cocoonin frame after treatement were fed on the just molted 3rd instar larvae, 82% of them died with disease during 6 days, and negative effect of formalin fumigation takes place in terms of the cocoon reelability, showing 41% of it.

  • PDF

Minimal Stimulation using rhFSH and GnRH Antagonist for IVF Treated Patients of Advanced Age (고령 불임여성의 체외수정술시 최소자극법의 효용성)

  • Kim, So-Ra;Kim, Chung-Hoon;Lee, Jin-Kyoung;Jeon, Gyun-Ho;Kim, Sung-Hoon;Chae, Hee-Dong;Kang, Byung-Moon
    • Clinical and Experimental Reproductive Medicine
    • /
    • v.36 no.1
    • /
    • pp.63-70
    • /
    • 2009
  • Objective: This study was performed to investigate the effectiveness of minimal stimulation using rhFSH and GnRH antagonist compared with GnRH antagonist multidose protocol (MDP) in IVF treated patients with aged 40 and above. Methods: Seventy-five patients with aged 40 and above were equally randomized to minimal stimulation group (n=37) or GnRH antagonist MDP group (n=38). For minimal stimulation group, ultrasound monitoring was started on cycle day 7 or 8. Daily injections of 0.25 mg cetrorelix together with 150 IU rhFSH were started from the day at 13${\sim}$14 mm of a leading follicle diameter. For GnRH antagonist MDP group, daily injections of 225 IU rhFSH were initiated from cycle day 2 and GnRH antagonist was started at a dose of 0.25 mg/day on rhFSH stimulation day 6 or the day at 13${\sim}$14 mm of leading follicle diameter. In both groups, transvaginal ultrasound-guided oocyte retrieval was performed. According to cleavage and morphologic characteristics of embryos, embryos were transferred 3 to 5 days after oocyte retrieval. Results: There were no differences in patients' characteristics and cycle cancellation rate between the two groups. Total dose and duration of rhFSH used were significantly fewer and shorter in minimal stimulation group than those in GnRH antagonist MDP group. The numbers of oocytes retrieved, mature oocytes and transferred embryos were also lower in minimal stimulation group. However, there were no significant differences in the clinical pregnancy rate and miscarriage rate between the two groups. Conclusions: This study demonstrates that minimal stimulation protocol provides comparable pregnancy rates to GnRH antagonist MDP with fewer dose and days of rhFSH used, and thus can be a cost-effective alternative in women aged 40 and above.

Comparative Study on the Regulations about In-Use Stability, and Analysis the In-Use Stability Application on Approved Syrups - Focused on the Guidelines in US, Europe and Korea - (국내외 의약품 개봉 후 안정성 규정 비교와 국내 시럽제의 안정성 적용 현황 분석 - 미국, 유럽, 한국의 가이드라인을 중심으로 -)

  • Park, Onnuri;Jang, Kyoung won;Ha, Dong mun
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.21 no.3
    • /
    • pp.137-146
    • /
    • 2020
  • Syrup agents are often used after opening, and therefore, there is a high possibility of decreased quality. The Ministry of Food and Drug Safety (MFDS) published guideline on stability testing for pharmaceuticals after opening in December, 2016. We compared guidelines related to the period of use after opening between the United States of America (USA), Europe (EU), and Korea, and we analyzed whether the period of use or storage conditions is stated based on the data of drug approval for 4 dry syrups and 3 large packing syrups before and after the introduction of the guideline. First, in USA and EU, the period of use and storage conditions after opening should be listed on the label on the packaging container (as well as the expiration date), while in Korea, those are included in the area of precautions for use. Second, all of the analyzed drugs were not changed by the guidelines for establishing the new post-opening period of use, and they were only presented for the existing expiration date prior to the establishment of the guideline. Medicines that are used for multiple uses after opening may need improved instructions to ensure that the period of use and storage conditions are listed on the packaging according to stability evaluation after opening.

Analysis of Glass Bottle using Glass Bottle Lightness Index (유리병 경량화 지수를 이용한 유리병 포장용기 분석)

  • Kim, Sun-Jong;Jang, Si-Hoon;Kim, Ki-Tae;Lee, Yu-Suk;Park, Su-Il
    • KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
    • /
    • v.19 no.2
    • /
    • pp.109-115
    • /
    • 2013
  • Glass bottle lightness index has been used as a guideline for the lightness of glass bottle. In this study, we developed a glass bottle lightness index (L) by modifying Emhart's lightness index. Domestic and foreign glass bottle products were collected in Korean market and classified into two groups, returnable bottle and one way glass bottle. Emptied glass bottle weight and volume were measured and written product's content volume were recorded to calculate the L value. Based on L value, 'acceptable' and 'optimum' criteria for design guideline of glass bottle were established for both returnable and one way glass bottles. Many of one way glass bottles failed to meet acceptable criteria (L=1.0), while returnable glass bottles mostly satisfied acceptable range (L=1.4). Few of one way glass bottles were even heavier than returnable glass bottles. Generally lightness index (L) of small size drink glass bottles (100 ml) were above 1.0, while these of juice glass bottles (180 ml) were close to acceptable criteria. Most foreign sauce glass bottles met the acceptable level, however most domestic souse glass bottles failed to satisfy acceptable criteria. A few foreign beer glass bottles satisfied optimum criteria, while most domestic beer glass bottles were acceptable level. Our results reveal that domestic glass bottles are mostly heavier than foreign glass bottles. In this paper, we suggest the use glass bottle lightness index as a design guideline for material resource reduction of glass bottle for Korean food and beverage industries.

  • PDF

Temperature Measurement and Intelligent Access Management System Service Platform Advancement Research using AI Facial Recognition Technology (AI 얼굴정보처리기술을 활용한 체온측정 및 지능형 출입관리 시스템 서비스플랫폼 고도화 연구)

  • Kim, Byung-Wan
    • Journal of Korea Entertainment Industry Association
    • /
    • v.15 no.7
    • /
    • pp.249-257
    • /
    • 2021
  • Recently, interest and demand for facial information processing technology that can provide non-face-to-face identity authentication and access management service using smart devices, which is an essential environmental improvement for multi-use facilities, is increasing as a way to prevent the spread of infectious diseases worldwide and to cope with social measures. This study defines a multi-use facility classification system and applied service field to establish a continuous access control system, and measures to improve the usability of the service platform considering scalability through a dual access control system and personal/measurement information type analysis, and accordingly We would like to propose a service roadmap. In addition, it aims to improve the physical access management system service platform, which is a multi-use facility application service that requires one-time and multiple-use authentication according to usage. It is expected that the methodology of this study can be applied as a service platform of a logical access control system type in the future.

참돔 노지종묘생산과 요각류 번식을 위한 적정 시비제

  • 방인철;박상용;권성민;신현웅
    • Proceedings of the Korean Aquaculture Society Conference
    • /
    • 2003.10a
    • /
    • pp.3-63
    • /
    • 2003
  • 우리나라 서해안의 폐염전 또는 대하양식장을 이용한 해산어 종묘생산이 조피볼락, 감성돔, 숭어 등을 대상으로 이루어지고 있다. 이렇게 생산된 종묘는 기형개체가 전혀 없는 건강 종묘이며, 생산 원가 또한 육상수조식에 비해 최고 5배정도 낮다. 한편 참돔은 육상수조에서 종묘생산시 기형률이 비교적 높게 나타나므로 노지를 이용한 종묘생산이 요구되고 있다. 현재 노지 종묘생산시 요각류 번식을 위한 시비제로는 암모니아, 인산염, 칼륨 등이 함유되어 있는 화학비료(요소, 복합비료)나 계분, 돈분, 우분 등의 유기질 비료가 주로 사용되고 있다. 그러나 화학비료를 사용시 급격한 수질변화로 요각류의 폐사가 발생하고, 매년 지속적인 생산량을 기대하기가 어려운 문제점이 있다. 따라서 적절한 시비제를 구명하기 위하여 유기질 비료(알팔파, 숙성계분)와 화학비료(요소, 복합)를 단독 또는 병행 사용하여 2개월간의 동ㆍ식물플랑크톤의 변동량과 치어의 생존율을 조사한 결과, 유기질 비료는 부화자어가 입식된 이후에도 연속하여 시비하여도 생존율에 영향을 미치지 않았으나, 화학비료의 경우 일정 농도 이상에서는 동ㆍ식물플랑크톤의 번식에 장애를 초래하였고 이에 따라 자어가 전량 폐사하였다. 실험군의 생존율은 육상수조에서 40%, 알팔파와 숙성계분을 시비한 실험군이 15%, 요소, 복합, 알팔파를 시비한 실험군이 10%, 요소, 복합, 숙성 계분을 시비한 실험군이 8%, 요소와 복합을 시비한 실험군은 0%를 나타내었다. 또한 기형률에 있어 노지 실험군은 0.7%로 매우 낮게 나타났으나, 육상수조 실험군은 61%에 해당하는 치어가 기형이었으며, 그 형태도 다양하게 나타났다.fer, Artemia sp., copepods, 부화 25일째부터는 copepods였다. 초기성장은 부화직후 전장 1.95 mm였던 것이 10일째는 2.96 mm, 20일째는 3.89 mm, 30일째는 12.9 mm, 50일째는 35.1 mm를 나타내었다. 그러나 말쥐치 자ㆍ치어가 성장함에 따라 발생하는 지속적인 폐사와 종묘의 수송시 발생하는 폐사를 줄일 수 있는 방법이 추후에 해결되어야 할 것으로 사료된다.8,000~215,000 마리의 자어를 낳아서 개체에 따라 큰 차이를 나타내었다. 1999년에는(어미 : 전장 20.7~25.5cm, 체중 205.5~396.4g) 1 회 출산때마다 7,000~50,000 마리의 자어를 출산하였다. 3. 출산간격. 다회 출산한 쏨뱅이 어미가 첫 번째 출산에서 다음 출산까지 소요되는 기간을 조사한 결과 13일에서 25일이 걸리는 것으로 나타났다. 특히 4회 출산 한 1998년 쏨뱅이 어미는 첫 번째 출산 후 19일만에 두 번째 출산이 이루어 졌고 각각 13 일과 14 일만에 세 번째, 네 번째 출산이 이루어져 총 46일 동안 4회에 거쳐 자어를 출산하였다. 4. 출산자어의 크기. 1997년 3회 출산한 쏨뱅이의 출산시기별 자어 크기를 조사한 결과 첫 번째 출산에서는 평균전장 4.1$\pm$0.07mm의 자어를 낳았으나 두 번째 출산에서 자어의 크기는 평균전장이 3.9$\pm$0.11mm, 세 번째 3.8$\pm$0.12mm로 점차 작은 경향을 나타내었다..27mm(평균 1.76mm, n=20) 그리고 Snout length 0.74~l.67mm(평

  • PDF

Improvement of Occasional Artificial Hatching and Incubation Method in Diapause Egg of the Wild Silkmoth, Antheraea yamamai (천잠알의 수시부화 및 최청법 개선)

  • Yoon, Hyung-Joo;Kang, Pil-Don;Lee, Sang-Mong;Kim, Sam-Eun;Kim, Ki-Young
    • Korean journal of applied entomology
    • /
    • v.46 no.2
    • /
    • pp.295-302
    • /
    • 2007
  • We investigated starvation of hatching larvae, occasional artificial hatching and incubation method to establish year-round rearing of the wild silkmoth, Antheraea yamamai. In the test of starvation of hatching larvae for brushing at a time, the survival rate of the fourth instar of larvae starved for 1 day after hatching in $25^{\circ}C\;and\;5^{\circ}C$ was 83.3% and 96.0%, respectively. The result represents that the survival rate is high at low temperature during starvation. In the occasional artificial hatching test for multi-times rearing of A. yamamai, the useful hatchability is high at $5^{\circ}C$ in case of preserving eggs for 2 months from incubation time, and at both $2.5^{\circ}C\;and\;0^{\circ}C$ in case of over 6 months. A new incubation method with pre-incubation at $15^{\circ}C$ and 24 D photoperiod showed high hatchability about 80% for only 2 days compared with hatching for 5-6 days in traditional incubation method with the preservation at $25^{\circ}C$.

The Material Analysis and a Study on the Conservation Treatment of Taejo's Portrait Mounting Decorative Knots in the National Palace Museum of Korea Collection (국립고궁박물관 소장 태조어진 장황 유소의 재질분석 및 보존처리 방안 연구)

  • Lee, Seung Lee;Wi, Koang Chul
    • Journal of Conservation Science
    • /
    • v.31 no.1
    • /
    • pp.65-73
    • /
    • 2015
  • The purposes of this study are helping the understanding on the Dae-hwe kind relics, verifying the deformation rate stability during conservation treatment and enhancing the conservation treatment work by investigating the status and analyzing the material of Taejo's portrait mounting decorative knots in the National Palace Museum of Korea collection. The result of material analysis on the decorative knots was that the outer threads are silk threads, inner threads are cotton threads, the width of the metal threads was $500{\sim}600{\mu}m$ and the major component of it was 55wt% copper. The result of verification on the deformation rate during the form correction of the bell tassel was that it has been found as stable by having the deformation rate of 1 TPCM or less. The result of glue selection test to be used on the repairing of tassel cross-section with its thread cut was that wheat starch adhesive has been found most appropriate because it has the highest tensile strength at all concentrations. The conservation and treatment procedure was established based on above results of analysis and test on the relic and the conservation treatment work including packaging has been completed in accordance with the established procedure.

Alcohol Volume Consumed and Dependancy According to Venue and Multiple Drinking Rounds (음주차수 증가에 따른 장소별 음주량과 알코올 의존)

  • Lee, Geum-Seon;Yun, Mi-Eun
    • The Journal of the Korea Contents Association
    • /
    • v.21 no.2
    • /
    • pp.215-226
    • /
    • 2021
  • The purpose of this study was to analyze the alcohol volume consumed and alcohol dependancy according to multiple rounds of drinking. Sectional data collected in 2012 as part of an International Alcohol Control Study were used, and 855 of 1,789 drinker aged 19 to 64 were conducted. The proportion of multiple rounds drinking were significantly higher in males(χ²=37.607, p<.001), students(χ²=52.466, p<.001), single(χ²=34.205, p<.001), smoking experience and stressed(χ²=40,09, p<.001; χ²=21.66, p<.001) among drinkers. In particular, the alcohol volume consumed of unmarried people, smokers, and stress groups were significantly higher than married people, non-smokers and no-stress group. The highest alcohol intake in the first, 2nd and third rounds was found in bars in the liquor trade (F=67.8g, p<0.001). The total alcohol intake increased as the number of rounds increased (F=209.993, p=0.001) and the number of drinkers who tested positive for alcohol dependency increased, using the tests RAPS4 and DSM-IV(F=129.836, p<0.001; F=94.669, p<0.001). The OR of alcohol dependancy in males was 2.3(95% CI: 1.745-3.057), unemployed was 3.2(95% CI: 1.053-9.838), smokers was 3.9(95% CI: 1.230-12.292), and stress group was 2.1(95% CI: 1.561-2.768) compared to females, employed, non-smokers, and no-stress group respectively. In conclusion, it suggests that those consuming multiple rounds drinking can become more vulnerable to alcohol harms due to its relation to smoking, stress and increased dependence on alcohol.

Effects of Administration of Oxytocin Antagonist on Implantation and Pregnancy Rates in Patients with Repeated Failure of IVF/ICSI Treatment (체외수정시술의 반복적인 실패 환자에서 옥시토신 길항제 주입이 착상 및 임신에 미치는 영향)

  • Ahn, Jun-Woo;Kim, Chung-Hoon;Kim, So-Ra;Jeon, Gyun-Ho;Kim, Sung-Hoon;Chae, Hee-Dong;Kang, Byung-Moon
    • Clinical and Experimental Reproductive Medicine
    • /
    • v.36 no.4
    • /
    • pp.275-281
    • /
    • 2009
  • Objective: This study was performed to evaluate the effect of oxytocin antagonist on the outcome of IVF/ICSI cycles in infertile patients with repeated failure of IVF/ICSI treatment. Method: Forty patients who had experienced two or more failures of IVF/ICSI treatment without low ovarian reserve, were recruited for this prospective randomized study. All patients received controlled ovarian stimulation (COS) using GnRH antagonist multidose protocol (MDP). For the intervention group, intravenous administration of atosiban (mixed vasopressin $V_{1A}$/oxytocin antagonist) started with a bolus dose 6.75 mg one hour before embryo transfer (ET) and continued at an infusion rate of 18 mg/hour. After ET, administered atosiban was reduced to 6 mg/hour and continued for 2 hours. The main efficacy endpoints were clinical pregnancy rate and implantation rate. Results: Patients' characteristics were comparable in the intervention and control groups. COS parameters and IVF results were also similar. The number of uterine contractions for 3 minutes measured just before ET was significantly lower in the intervention group than control group ($3.5{\pm}1.4$ vs $8.7{\pm}2.2$, p<0.001). While there was no statistically significant difference in the clinical pregnancy rate between control group and intervention group (20.0% and 40.0%, p=0.168), the implantation rate was significantly higher in the intervention group, with 16.9% (11/65) compared with 6.0% (4/67) in the control group (p=0.047). There were no differences in ectopic pregnancy rate and miscarriage rate between the two groups. Conclusion: This study demonstrates that administration of oxytocin antagonist during ET can improve the implantation rate probably by decreasing the frequency of uterine contractions in infertile patients undergoing IVF/ICSI treatment.