• Title/Summary/Keyword: 뇌연구

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Implicit Distinction of the Race Underlying the Perception of Faces by Event-Related fMRI (Event-related 기능적 MRI 영상을 통한 얼굴인식과정에서 수반되는 무의식적인 인종구별)

  • Kim Jeong-Seok;Kim Bum-Soo;Jeun Sin-Soo;Jung So-Lyung;Choe Bo-Young
    • Investigative Magnetic Resonance Imaging
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    • v.9 no.1
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    • pp.43-49
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    • 2005
  • A few studies have shown that the function of fusiform face area is selectively involved in the perception of faces including a race difference. We investigated the neural substrates of the face-selective region called fusiform face area in the ventral occipital-temporal cortex and same-race memory superiority in the fusiform face area by the event-related fMRI. In our fMRI study, subjects (Oriental-Korean) performed the implicit distinction of the race while they consciously made familiar-judgments, regardless of whether they considered a face as Oriental-Korean or European-American. For race distinction as an implicit task, the fusiform face areas (FFA) and the right parahippocampal gyrus had a greater response to the presentation of Oriental-Korean faces than for the European-American faces, but in the conscious race distinction between Oriental-Korean and European-American faces, there was no significant difference observed in the FFA. These results suggest that different activation in the fusiform regions and right parahippocampal gyrus resulting from superiority of same-race memory could have implicitly taken place by the physiological processes of face recognition.

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A study on Health healing method for incite to the brain of the part of the visual nerve and auditory (3D 영상 기반에서 시각 및 청각 뇌 자극을 이용한 가상현실 건강치유기법에 관한 연구)

  • Jeong, Yang-Kwon
    • The Journal of the Korea institute of electronic communication sciences
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    • v.3 no.4
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    • pp.233-239
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    • 2008
  • This study is study regarding system implementation that a ruler maximizing an autoimmunity effect supported it as I stimulate I am visual hearing so that treatment ability is possible. As I am known in a lot of conspiracy mental problems by being disproportionate for a direct reason to be connected to an action, the brain whom emotional, govern spirits through fragrance to stimulate sense of smell so that, specially, an ARoMa treatment is effective. I will inquire into changes and an influence around alpha of the rear wave object before watching this system.

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Practical Considerations of Arterial Spin Labeling MRI for Measuring the Multi-slice Perfusion in the Human Brain (스핀 라벨링 자기공명영상을 이용한 사람 뇌에서의 뇌 관류영상의 현실적 문제점을 향상 시키는 방법 연구)

  • Jahng, Geon-Ho
    • Progress in Medical Physics
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    • v.18 no.1
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    • pp.35-41
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    • 2007
  • In this work practical considerations of a pulsed arterial spin labeling MRI are presented to reliable multi-slice perfusion measurements In the human brain. Three parameters were considered in this study. First, In order to improve slice profile and Inversion efficiency of a labeling pulse a high power Inversion pulse of adiabatic hyperbolic secant was designed. A $900^{\circ}$ rotation of the flip angle was provided to make a good slice profile and excellent Inversion efficiency. Second, to minimize contributions of a residual magnetization be4ween Interleaved scans of control and labeling we tested three different conditions which were applied 1) only saturation pulses, 2) only spotter gradients, and 3) combinations of saturation pulses and spotter gradients Applications of bo4h saturation pulses and spoiler gradients minimized the residual magnetization. Finally, to find a minimum gap between a tagged plane and an imaging plane we tested signal changes of the subtracted image between control and labeled Images with varying the gap. The optimum gap was about 20mm. In conclusion, In order to obtain high quality of perfusion Images In human brain It Is Important to use optimum parameters. Before routinely using In clinical studios, we recommend to make optimizations of sequence parameters.

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The Effects of Self-Growth Group Program on Emotional Intelligence and Brain Function Index of Nursing Students. (자기성장집단 프로그램이 간호대학생의 감성지능, 뇌기능 지수에 미치는 효과)

  • Park, Hye-In;Lee, Kyunghee
    • Journal of Digital Convergence
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    • v.16 no.1
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    • pp.243-250
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    • 2018
  • This study is a single-group experimental study to determine the effects on self-growth group programs are emotional intelligence and brain function index of Nursing Students. The data were collected between August 22 and September30, 2017. A total of 38 Nursing Students at k city were participated. The collected data were analyzed using frequency, mean and standard deviation, t-test, ANOVAs, and Repeated ANOVA. Self-growth group program showed differences in emotional intelligence over time and Emotional self-understanding showed a statistically significant difference between group and time. The brain function index is no statistically significant difference between group and time but showed a difference in time. The results of self - growing group program has a significant effect on the self - understanding of nursing college students and Brain function index. This study suggests the necessity that the self growth group program for self-understanding, others-understanding, self-opening of nursing students will help improve emotional intelligence.

Imaging Studies in Mouse Brain Using Clinical 3T MRI Scanner (임상용 3T MRI를 이용한 마우스 뇌의 영상)

  • Lim, Soo-Mee;Park, Eun-Mi
    • Progress in Medical Physics
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    • v.21 no.4
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    • pp.348-353
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    • 2010
  • The purpose of this study was to explore the potentials of a clinical 3T MRI in mouse brains and technical adaptation and optimization. T1-weighted images (T1WI), T2-weighted images (T2WI), FLAIR (Fluid Attenuated Inversion Recovery) images, Gadolinium enhanced T1-weighted images (Gd-T1WI), Diffusion weighted images (DWI) were acquired in brain of 2 mice (weight 20~25 g) with cerebral infarction by occlusion of right middle cerebral artery, 1 hour, 24 hours, 72 hours after infarction and 1 normal mouse brain using clinical 3T MRI scanner. We analyzed differentiation of striatum, ventricle, cerebral cortex, and possibility of detection of acute cerebral infarction. We could differentiate the striatum, ventricle, cerebral cortex on T2WI and on DWI, FLAIR, T1WI, the differentiation of each anatomy of brain was not definite, but acute cerebral infarction was detected on DWI of 1 hour, 24 hours, 72 hours after infarction and on T2WI, FLAIR of 24 hours, 72 hours after infarction. Clinical 3T MRI can be used in differentiation of anatomy of mouse brains and DWI can be helpul in detection of acute cerebral infarction in acute phase. With technical adaptation and optimization clinical 3T MRI can be useful tool for provide preclinical and clinical small animal studies.

The Significance of Electroencephalography in the Hypothermic Circulatory Arrest in Human (인체에서 저체온 완전 순환 정지 시 뇌파검사의 의의)

  • 전양빈;이창하;나찬영;강정호
    • Journal of Chest Surgery
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    • v.34 no.6
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    • pp.465-471
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    • 2001
  • Background: Hypothermia protects the brain by suppressing the cerebral metabolism and it is performed well enough before the total circulatory arrest(TCA) in the operation of aortic disease. Generally, TCA has been performed depending on the rectal or nasopharyngeal temperatures; however, there is no definite range of optimal temperature for TCA or an objective indicator determining the temperature for safe TCA. In this study, we tried to determine the optimal range of temperature for safe hypothermic circulatory arrest by using the intraoperative electroencephalogram(EEG), and studied the role of EEG as an indicator of optimal hypothermia. Material and Method: Between March, 1999 and August 31, 2000, 27 patients underwent graft replacement of the part of thoracic aorta using hypothermia and TCA with intraoperative EEG. The rectal and nasopharyngeal temperatures were monitored continuously from the time of anesthetic induction and the EEG was recorded with a ten-channel portable electroencephalography from the time of anesthetic induction to electrocerebral silence(ECS). Result: On ECS, the rectal and nasopharyngeal temperatures were not consistent but variable(rectal 11$^{\circ}C$ -$25^{\circ}C$, nasopharynx 7.7$^{\circ}C$ -23$^{\circ}C$). The correlation between two temperatures was not significant(p=0.171). The cooling time from the start of cardiopulmonary bypass to ECS was also variable(25-127min), but correlated with the body surface area(p=0.027). Conclusion: We have found that ECS appeared at various body temperatures, and thus, the use of rectal or nasopharyngeal temperature were not useful in identifying ECS. Conclusively, we can not fully assure cerebral protection during hypothermic circulatory arrest in regards to the body temperatures, and therefore, the intraoperative EEG is one of the necessary methods for determining the range of optimal hypothermia for safe circulatory arrest. :

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The Forming Mechanism of Brain Text and Brain Concept in the Theory of Ethical Literary Criticism (뇌텍스트(Brain Text) 및 뇌개념(Brain Concept)의 형성원리와 문학윤리학비평)

  • Nie, Zhenzhao;Yoon, Seokmin
    • Journal of Popular Narrative
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    • v.25 no.1
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    • pp.193-215
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    • 2019
  • According to ethical literary criticism, every type of literature has its text. The original definition of oral literature refers to the literature disseminated orally. Before the dissemination, the text of oral literature is stored in the human brain, which is termed as "brain text". Brain text is the textual form used before the formation of writing symbols and its application to a recording of information, and it still exists after the creation of writing symbols. Other types of texts are written text and electronic text. Brain text consists of brain concepts, which, according to different sources, can be divided into objective concepts and abstractive concepts. Brain concepts are tools for thinking while thought comes from thinking with understanding and an application of brain concepts. Brain text is the carrier of thought. The termination of the synthesis of brain concepts signifies the completion of thinking, which produces thoughts to form brain text. Brain text determines thinking and behavioral patterns that not only communicate and spread information, but also decide our ideas, thoughts, judgments, choices, actions and emotions. Brain text is also a deciding factor for our lifestyle and moral behaviors. The nature of a person's brain text determines his thoughts and actions, and most importantly determines who he is.

뇌파 조절 수행이 학습 향상에 미치는 영향의 실증적 연구

  • 윤상원;서용성;홍순욱
    • Proceedings of the ESK Conference
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    • 1996.10a
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    • pp.56-56
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    • 1996
  • 인간의 사고 기능과 학습기능이 '뇌'를 바탕으로 이루어진다고 할 때, 뇌의 긴장을 풀어 원래의 건강하고 창조적인 이완 상태에서의 학습 상태가 유효하게 된다. 즉, 뇌파가 " $\alpha$" 상태 가 되었을 때 긴장된 신체의 각 부분이 충분히 이완되고 두뇌는 맑고 건강한 상태를 유지하여 활발하고 창조적인 상태가 된다. 뇌파의 측정 및 분석된 기존 연구에 의하면, 인간의 심리상태와 신체 상태, 행동 패턴에도 직, 간접적인 영향을 주어 뇌파의 조절이 인간 잠재능력 개발의 첩경이라는 결과가 보고되어진다. 이러한 관점에서 본 연구에서는 뇌의 특성을 고려하여 뇌를 이완시킴으로써 학생들의 학습능력을 향상시키 기 위한 새로운 접근 방법을 시도한다. 뇌파 조절이 가해지는 환경하에 학습 효율의 변화 정도를 정성적( 심리적, 학습적, 신체적) 및 정량적(영어 단어 암기력 TEST, 뇌파 특정 등)으로 평가 및 분석을 통해 뇌파 조절 효과가 학생들의 학습 효율을 더욱 향상 시킬 수 있는 지의 타당성을 검증하고 그 결과를 바탕으로 새로운 학습 방법을 모색하고자 한다. 한편, 본 연구에서는 실험 대상을 본 대학 임의의 2학년 학생 13 명 을 대상으로 하고 실험기간은 약 4개월에 걸쳐 실험 하였다. 뇌파 측정은 13명중 임의의 학생 7명을 선정 하여 각 40분씩 측정 분석하였다. 또한 영어 단어 암기력 TEST를 실시하여 그 결과를 뇌파 조절 전,후로 나누어 비교 분석하였다. 정성적 분석으로서 종합 설문지를 이용한 15 개 항목의 5점 척도를 사용하여 분석하였으며 가가 통계 이론을 이용하여 검증하였다. 뇌파 측정은 수행 전후 비교 결과 " .alpha. " 노출 비율이 수행 전보다 수행 후가 다소 높은 비유로 나타났으며, 특히 영어 단어 암기력은 평균적으로 크게 상승되는 것으로 나타났다. 정성적 분석 결과에서는 많은 심리적 변화 상태가 나타나고 있지만 전체적으로 마음의 안정감, 몸의 긴장 이완에 따른 건강 상태 유지, 수업 집중도 향상 등이 나타났다. 위와 같은 종합 적 분석 결과에 따라, 본 연구는 제조 현장의 생산성 향상 및 품질 향상과 연계하여 작업자의 작업 집중도 향상, 작업자의 육체적, 심리적 변화에 따른 생산성 및 품질 향상 변화 정도 등의 산업공학(인간공학) 제 분야의 여러 측면에서 연구 및 적용이 가능하리라 사료된다.

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Semi-automated Tractography Analysis using a Allen Mouse Brain Atlas : Comparing DTI Acquisition between NEX and SNR (알렌 마우스 브레인 아틀라스를 이용한 반자동 신경섬유지도 분석 : 여기수와 신호대잡음비간의 DTI 획득 비교)

  • Im, Sang-Jin;Baek, Hyeon-Man
    • Journal of the Korean Society of Radiology
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    • v.14 no.2
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    • pp.157-168
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    • 2020
  • Advancements in segmentation methodology has made automatic segmentation of brain structures using structural images accurate and consistent. One method of automatic segmentation, which involves registering atlas information from template space to subject space, requires a high quality atlas with accurate boundaries for consistent segmentation. The Allen Mouse Brain Atlas, which has been widely accepted as a high quality reference of the mouse brain, has been used in various segmentations and can provide accurate coordinates and boundaries of mouse brain structures for tractography. Through probabilistic tractography, diffusion tensor images can be used to map comprehensive neuronal network of white matter pathways of the brain. Comparisons between neural networks of mouse and human brains showed that various clinical tests on mouse models were able to simulate disease pathology of human brains, increasing the importance of clinical mouse brain studies. However, differences between brain size of human and mouse brain has made it difficult to achieve the necessary image quality for analysis and the conditions for sufficient image quality such as a long scan time makes using live samples unrealistic. In order to secure a mouse brain image with a sufficient scan time, an Ex-vivo experiment of a mouse brain was conducted for this study. Using FSL, a tool for analyzing tensor images, we proposed a semi-automated segmentation and tractography analysis pipeline of the mouse brain and applied it to various mouse models. Also, in order to determine the useful signal-to-noise ratio of the diffusion tensor image acquired for the tractography analysis, images with various excitation numbers were compared.

뇌조직으로부터 정제한 Succinic semialdehyde reductase의 정제 및 활성기작 연구

  • 최수영;송민선;최의열;조성우
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1994.04a
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    • pp.271-271
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    • 1994
  • NADPH-dependent succinic semialdehyde reductase를 소의 뇌조직으로부터 여러가지 크로마토그래픽 방법을 이용하여 순수 분리 정제하였다. 효소는 분자량 34kDa을 가진 monomeric 단백질이며 substrate specificity. 분자량, 최적 pH, 아미노산 조성 등을 다른 sources의 효소들과 비교하였다. 이 비교 결과들로부터 본 연구에서 정제한 효소는 다른 sources와 다른 효소로 밝혀졌다. 반응의 산물이나 유사 기질 등을 저해제로 사용하였을때의 반응기작은 intermediate ternary complex를 형성하고 NADPH가 먼저 효소에 binding하는 ordered Sequencial mechanism을 보인다는 사실을 관찰할 수 있었다.

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