• Title/Summary/Keyword: 노출인자

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Incidence and Procedure-Related Risk Factors of Delirium in Patients Admitted to an Intensive Care Unit (중환자실 입원 환자의 섬망 발생과 처치 관련 위험인자)

  • Ahn, Jee Seon;Oh, Jooyoung;Park, Jaesub;Kim, Jae-Jin;Park, Jin Young
    • Korean Journal of Psychosomatic Medicine
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    • v.27 no.1
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    • pp.35-41
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    • 2019
  • Objectives : Although delirium is a common complication among patients hospitalized in intensive care units(ICUs), little is known about the roles that diagnostic and therapeutic procedures play in its development. This study investigates the procedure-related risk factors of delirium in ICU patients. Methods : All the consecutive patients admitted to the ICU between June 2016 and May 2017 were routinely evaluated for delirium by psychiatrists. In total, 1156 patients met the inclusion criteria and were retrospectively analyzed. A multiple logistic regression analysis was conducted to investigate independent risk factors of delirium development while adjusting for other characteristics. Results : The age, Acute Physiology and Chronic Health Evaluation (APACHE II) score, proportion of patients who had undergone an operation, and proportion of patients who were foley catheterized, mechanically ventilated, and physically restrained were higher in the delirium group. The multiple logistic regression analysis confirmed that the use of restraint was an independent risk factor of delirium (odds ratio : 10.006 ; 95% confidence interval : 6.120-16.360 ; p<0.001). The patient factors independently associated with delirium were an advanced age and a higher APACHE II score. The incidence of delirium was 15.3%. Conclusions : There is a high prevalence of delirium influenced by potentially harmful procedures in patients in ICU settings. The use of physical restraint had the strongest association with the development of delirium. These findings advocate the need to target procedure-related risk factors such as the use of restraints as preventive intervention measures for ICU delirium.

Exposure Assessments of Chemical Risk Factors to Airborne Contaminants in Foundry Process (주물사업장 내 공기중 화학적 유해인자 노출 평가)

  • Bae, Hye-Jeong;Nam, Mi-Ran;Lee, Sang-Man;Jung, Yu-Jin;Shon, Byung-Hyun;Phee, Young-Gyu;Jung, Jong-Hyeon
    • Journal of Environmental Science International
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    • v.24 no.5
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    • pp.699-708
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    • 2015
  • This study was performed to identify the state of the exposure and characteristics of pollutants by each process at 4 casting sites located in Gyeongsang-do from April to November 2013. The concentrations of methanol, crystallized silica glass, formaldehyde and phenol were analyzed by different process - casting process, molding process, core process, and shakeout & finishing process. The highest concentration of methanol was found in casting and molding process, whereas the highest concentration of crystalline quartz(Silica) was observed in core process. The most oxidized steel dusts and the highest concentration of fume were found in shakeout & finishing process. As a result of this study, those labors working at the casting site were found to be constantly exposed to various forms of hazardous chemicals; therefore, it is considered that this is the time to manage and plan how to reduce them. In addition, it is required to thoroughly manage the local exhauster, and improve the process and working environment to reduce various forms of hazardous chemicals.

Accelerated Life Testing and Validity Evaluation of Finger Strips Used for Electromagnetic Shielding Doors (전자파 차폐 도어용 핑거 스트립의 가속수명시험 및 유효성 평가)

  • Lee, Joo Hong;Kim, Do Sik;Chang, Mu Seong;Cho, Hae Yong
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.39 no.9
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    • pp.831-837
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    • 2015
  • Many persons and electronic devices are exposed to electromagnetic (EM) waves generated from magnetic resonance imaging (MRI) equipment, EM pulses (EMPs), and many other kinds of EM wave devices. Finger strips are used to provide shielding from these EM waves. Because of the high thermal conductivity of finger strips, they are used in the design of specialized doors that are installed in shielded rooms. In this study, we perform an accelerated life test using the load acceleration stress, which affects the main failure mode of finger strips. We predict the life of the finger strip under normal usage conditions based on the results of the accelerated life test. We compare the results with those predicted from the life test under normal usage conditions to evaluate the validity of accelerated life testing.

Exposure Assessment for Airborne Biological Agents in Sawmills (제재업의 생물학적인자 노출실태 평가)

  • Park, Hae-Dong;Park, Hyun-Hee;Lee, In-Seop
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.20 no.4
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    • pp.274-281
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    • 2010
  • The objectives of this study are (a) to investigate the distribution patterns and exposure concentrations of biological agents in sawmill industries and (b) to compare sampling methods of biological agents. The representative processes of 5 sawmills were selected to measure total airborne bacteria, fungi, endotoxin as well as dust. Airborne bacteria and fungi were measured with one stage impactor, six stage impactor and gelatin filteration methods. Endotoxin was collected with polycarbonate filters and analysed by kinetic chromogenic Limulus Amebocyte Lysate method. Geometric mean levels of airborne bacteria, fungi, endotoxin and dust were 1,864 CFU/$m^3$, 2,252 CFU/$m^3$, 31.5 EU/$m^3$ and 2.4 mg/$m^3$. The ratios of indoor/outdoor concentrations were 3.7 for bacteria, 4.1 for fungi, 3.3 for endotoxin and 9.7 for dust. The respiratory fractions of bacteria were 68.0, 50.9, 49.2 and 45.1% in band-saw, table-saw, rip-saw process and outdoor air. The respiratory fractions of fungi were 78.7, 90.8, 87.5 and 84.8% in band-saw, table-saw, rip-saw process and outdoor air, respectively. There was no significant differences in bacterial concentrations among single stage, six stage impaction and filteration methods. But, fungal concentrations measured with filtration methods were significantly higher than those with impaction methods. Geometric mean levels of airborne bacteria and fungi were higher than the OSHA guideline values of 1,000 CFU/$m^3$. The respiratory fractions of fungi were above 75%. The concentrations of biological agents were significantly different among culture-based sampling methods. In the exposure assessments of biological agents, further studies are needed for the comparisons of diverse sampling methods and the investigations of environmental factors.

Properties of Temperature History of Lightweight Mortar for Fire Protection Covering Material in High Strength Concrete (고강도 콘크리트 내화피복용 경량 모르터의 온도이력 성상)

  • Lim, Seo-Hyung
    • Fire Science and Engineering
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    • v.26 no.6
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    • pp.45-50
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    • 2012
  • The spalling causes the sever reduction of the cross sectional area with the exposure of the reinforcing steel, which originates a problem in the structural behaviour. By coating surface of high strength concrete with fireproof mortar, the high strength concrete is protected from the spalling in fire and the method to constrain the temperature increase of steel bar within the concrete. The purpose of this study is to investigate the temperature history properties of lightweight mortar using perlite and polypropylene fiber for fire protection covering material. For this purpose, selected test variables were the contents and length of polypropylene fiber. As a result of this study, it has been found that addition of polypropylene fiber to mortar modifies its pore structure and this causes the internal temperature to rise. And it has been found that a new lightweight mortar can be used in the fire protection covering material.

A Study on DNA Degeneration by Comet Assay & Pathological Observation for Mouse Which were Exposed HCN Gases from Fire (화재로 인한 HCN 가스에 노출된 마우스의 병리학적 관찰 및 단세포 전기영동법을 사용한 DNA 변성 추적에 관한 연구)

  • Cho, Nam-Wook;Oh, Eun-Ha;Hwang, Sung-Kwy
    • Journal of the Korean Institute of Gas
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    • v.16 no.6
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    • pp.7-16
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    • 2012
  • Combustion Toxic Effects among several factors of risk encountered during fire are important in the evacuation and final survival, and they are broader and fatal than the direct damages caused by flame. Most studies on fire toxicity until the present are limited to fatality, mainly deaths by fire through pathological research. In this study, it is conducted as a fundamental experiment to address 3 principles of animal experiment and to provide an alternative test to animal testing that is regulated by national building codes and it was conducted through approval by the animal testing ethics committee. Hence, in this study average time of activity stop was measured after directly inhaling toxic gases (HCN) to laboratory animals (mice) through gas toxicity test (KS F 2271) for major asphyxiating gases(HCN) which are produced during fire combustion. effects of Combustion toxic gases on body were quantitatively analyzed through changes in internal organs and hematological analysis, and electrophoresis of a single cell of these laboratory animals. Biological conclusion of combustion toxicology is drawn through approaches (pathological examination, blood test, blood biochemical test, electrophoresis analysis of single cell) which could not confirmed in existing gas toxicity test.

A Study on MDA Analysis & blood chemical test for Mouse which were exposed HF Gases from Fire (화재로 인한 불화수소(HF)가스에 노출된 마우스의 혈액생화학분석 및 MDA분석을 통한 세포손상에 관한 연구)

  • Cho, Nam-Wook;Oh, Eun-Ha
    • Journal of the Korean Institute of Gas
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    • v.17 no.6
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    • pp.58-66
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    • 2013
  • Among the risks which can be faced with fire, combustion toxicity is a significant influence on the survival. Fire toxicity researches have been limited generally on the lethal aspects. In this study, HF gas which can be generated from fire, and also found in general industrial site was used for analysis. Blood analysis and biochemistry analysis performed to find internal demage of experimental animals which were used for measuring average activity stopping time from Animal test(KS F2271: Gas hazard test). In addition, Using the malondialdehyde analysis, indicators of oxidative damage, we had quantitative analysis to target lymphocyte for measuring the oxidative damage caused by toxic substances.

Analysis Technique on Time-dependent PDF (Probability of Durability Failure) Considering Equivalent Surface Chloride Content (균등 표면 염화물량을 고려한 시간 의존적 내구적 파괴확률 해석기법)

  • Lee, Hack-Soo;Kwon, Seung-Jun
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.21 no.2
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    • pp.46-52
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    • 2017
  • Recently durability design based on deterministic or probabilistic method has been attempted since service life evaluation in RC(Reinforced Concrete) structure exposed to chloride attack is important. The deterministic durability design contains a reasonable method with time effect on surface chloride content and diffusion coefficient, however the probabilistic design procedure has no consideration of time effect on both. In the paper, a technique on PDF(Probability of Durability Failure) evaluation is proposed considering time effect on diffusion and surface chloride content through equivalent surface chloride content which has same induced chloride content within a given period and cover depth. With varying period to built-up from 10 to 30 years and maximum surface chloride content from $5.0kg/m^3$ to $10.0kg/m^3$, the changing PDF and the related service life are derived. The proposed method can be reasonably applied to actual durability design with preventing conservative design parameters and considering the same analysis conditions of the deterministic method.

플라즈마 표면처리시 산소 분율의 변화가 기판의 표면에너지와 코팅층과의 계면 부착 특성에 미치는 영향

  • Kim, Dong-Yong;Bae, Gwang-Jin;Kim, Jong-Gu;Ju, Jae-Hun;Jo, Yeong-Rae
    • Proceedings of the Korean Vacuum Society Conference
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    • 2015.08a
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    • pp.110-110
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    • 2015
  • 표면에너지는 계면특성을 지배하는 핵심인자로 디스플레이의 터치 스크린 패널 공정, 이종소재의 접합, 금속의 클래딩 등 실제 산업에 있어서 매우 중요하다. 표면에너지는 코팅과 본딩 이론에 있어서 기본이 되는 물리량으로 표면에너지가 높을수록 코팅 또는 박막 증착시 코팅, 증착이 용이하며 이종소재의 접합도 쉽게 일어난다. 본 연구에서는 플라즈마 표면처리시 산소 분율의 변화에 따른 기판의 표면에너지와 코팅층과 기판의 부착력의 변화에 대해 연구하였다. 연구의 주요 기판으로 ITO, PET 기판을 사용하였고, 표면 에너지 변화를 확인하기 위해 기판을 상온 상압 플라즈마에 노출시켰다. 플라즈마는 아르곤(Ar)의 공급량을 20 LPM으로 고정하고 산소($O_2$)의 공급량을 0 sccm에서 40 sccm 까지 10 sccm 간격으로 변수를 주었다. 표면에너지 값은 기판 위에 형성된 액체의 접촉각을 통해 도출하였다. 표면에너지 측정 액체로 증류수(deionized water)와 디오도메탄(diiodo-methane)을 사용하였다. 표면에너지는 산소분압이 10 sccm에서 최대값인 76 mJ/m2으로 증가한 후 20 sccm까지 유지하다 다시 직선적으로 감소하였다. 기판에 증착된 크롬 박막의 부착력은 스크래치 테스트를 통해 측정하였다. 표면에너지의 증가와 비례하게 부착력은 증가하였고 표면에너지가 감소하는 범위에서는 부착력도 감소하였다. 기판과 코팅층의 부착력 증가 원인 중 하나인 계면 산화물 층의 생성 여부를 알아보기 위해 auger electron spectroscopy (AES) 분석을 진행하였다. AES 분석을 통해 플라즈마 표면처리시 기판과 코팅층의 계면 산화물층의 두께가 표면에너지의 변화와 비례하게 증가하였다가 감소하는 것을 확인하였다. 산소분압이 10 sccm 이었을 경우 산화물층의 두께가 가장 두꺼웠다. 또한 계면의 화학적 결합 상태를 알아보기 위해 X-ray photoelectron spectroscopy (XPS) 분석을 진행하였으며 산소 분율의 변화에 따라 크롬 산화물의 양이 증가하였다 감소하는것을 확인하였다. 이 연구를 통해 산소를 포함한 플라즈마 표면개질이 기판과 코팅층의 부착력 증가에 영향을 끼침을 확인 할 수 있었다. 또한 이를 응용하여 부착력 증가가 필요한 다양한 분야에서도 쉽게 적용시킬 수 있을 것이다.

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Stability Rating of KSR-III Rocket Engine (KSR-III 로켓엔진의 연소 안정성 평가)

  • Sohn, Chae-Hoon;Kim, Young-Mog
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.32 no.3
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    • pp.95-101
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    • 2004
  • Stability rating of KSR-III rocket engine is conducted based on stability rating tests in the course of development of KSR-III rocket engine. Rocket engine is approved to have combustion stabilization ability when it can suppress the external perturbation or pressure oscillation with finite amplitude and recover the original stable combustion. Rocket engine in flight may be perturbed by unexpectedly large-amplitude pressure oscillation and thus a designer should not only assure combustion stabilization ability of the engine but also quantify the stabilization capacity. For this, principal quantitative parameters and their evaluation are introduced. To verify dynamic stability of KSR-III rocket engine, six stability rating tests have been conducted. Based on these test results, such parameters are quantified and thereby, the stabilization capacity of KSR-III rocket engine is evaluated.