• Journal of Life Science
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• v.14 no.1
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• pp.131-140
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• 2004

T7 bacteriophage gp4 is the replicative DNA helicase that unwinds double-stranded DNA by utilizing dTTP hydrolysis energy. The quaternary structure of the active form of T7 helicase is a hexameric ring with a central channel. Single-stranded DNA passes through the central channel of the hexameric ring as the helicase translocates $5'\rightarrow3'$ along the single-stranded DNA. The DNA unwinding was measured by rapid kinetic methods and showed a lag before the single-stranded DNA started to accumulate exponentially. This behavior was analyzed by a kinetic stepping model for the unwinding process. The observed lag phase increased as predicted by the model with increasing double-stranded DNA length. Trap DNA added in the reaction had no effect on the amplitudes of double-stranded DNA unwound, indicating that the $\tau7$ helicase is a highly processive helicase. Global fitting of the kinetic data to the stepping model provided a kinetic step size of 10-11 bp/step with a rate of $3.7 s^{-1}$ per step. Both the mechanism of DNA unwinding and dTTP hydrolysis and the coupling between the two are unaffected by temperature from $4∼37^{\circ}C$. Thus, the kinetic stepping for dsDNA unwinding is an inherent property of tile replicative DNA helicase.

• Journal of the KSME
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• v.31 no.7
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• pp.616-625
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• 1991

운동하는 임의 강체의 순간속도는 플뤼커의 축좌표에 의한 트위스트로 표현될 수 있고 마찬가 지로 직렬형 로봇의 손의 운동 또한 한 개의 트위스트로써 순간속도를 표현할 수 있었으며, Jacobian이 나선좌표로 구성되어 있음을 알았다. 한편, 강체에 작용하는 힘은 플뤼커의 방사좌 표에 의한 치로 표현될 수 있으며, 역관계에 있는 두 나선에 의하여 표현된 트위스트와 치가 로봇의 역학적 해석에 어떻게 이용되는 가를 예를 들어 설명하였다. 이처럼 나선이론은 다 자 유도를 갖는 로봇의 운동 및 역학적 해석에 이용될 수 있는 효과적인 수학적도구라 할 수 있다. 나선은 하나의 기하적 요소이며, 복잡한 강체의 운동을 표현함에 있어서 간편함을 제공한다. 이미 한 세기 전 쯤에 소개된 나선이론이 근래에 와서 이와 같이 로봇의 운동해석에 활용되고 있음은 이러한 때문이라 할 수 있겠다. 나선이론은 이 글에서 설명이 생략된 로봇의 동역학적 해석에도 활용되며, 또한 병렬형 구조를 갖는 로봇(parallel robots)의 해석 등에서도 찾아 볼 수 있다.

• Journal of the Korea institute for structural maintenance and inspection
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• v.21 no.6
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• pp.1-9
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• 2017

Spiral reinforcement in a circular column plays an effective role in the ductile behavior of a column through position fixing and buckling restraining of the longitudinal reinforcement, and confining core-concrete. Each country has suggested the minimum volumetric ratio of spiral reinforcement in order to secure the ductility of concrete columns. The minimum volumetric ratio of spiral reinforcement suggested by ACI 318-14 and the national concrete structure design standard was developed based on the theory of Richard et al. (1928); furthermore it has been used until now. However, their theory cannot consider the effects of high strength concrete and high strength reinforcement, and arrangement condition of the spiral reinforcement. In this study, a modified minimum volumetric ratio equation is suggested, which is required to improve the ductility of reinforced concrete circular columns and to recover their stress. The modified minimum volumetric ratio equation suggested here considers the effect of the compressive strength of concrete, the yield strength of spiral reinforcement, the cross sectional area of columns, the pitch of spiral reinforcements and the diameter of spiral reinforcement. In this paper, the validity of the minimum volumetric ratios from ACI 318-14 and this study was investigated and compared based on the results of uniaxial compression experiment for specimens in which the material strength and the spiral reinforcements ratio were used as variables. In the end of the study, the modification method for the suggested equation was examined.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.1
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• pp.33-38
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• 2012

In this paper, helical wave wire have been proposed as the vehicle connector for the wireless access in vehicular environments(5.925GHz) communication. This helical slow wave connector is design by considering the properties of critical parameter like helical mean radius, helical pitch, helical wire radius and distance of helical wire to shield. The design simulation and results can be used to determine the most suitable helical wave wire dimensions for vehicle communication connector. The optimized WAVE connector inserted the helical wave wire has insertion loss less than -0.76dB at 5.925GHz. It provides 31% of insertion loss with good performance. Therefore, the simulated results can be effectively used for optimum design of high frequency connector for vehicle communication.

• Journal of the Korean Society for Aviation and Aeronautics
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• v.20 no.1
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• pp.34-38
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• 2012

호산구는 염증 반응에 의해 활성화되며, 주로 기생충 감염이나 알러지 질환 등에 대한 면역 작용을 담당한다고 알려져 있다. 호산구 증가증은 약물 반응, 알러지, 국소적인 기생충 감염 등에 의한 경우가 많지만, 자가면역성 질환이나 종양에 의한 경우도 있다. 최근 연구를 통해 위염의 대표적인 원인균 중 하나인 유문나선균 역시 위점막에서 나타나는 조직 호산구 증가증의 원인이 될 수 있다고 밝혀지고 있으나, 유문나선균에 의한 호산구 증가증 발생 기전이나 빈도는 아직까지 확립되지 않고 있다. 위점막 내 호산구 침윤과 동반되는 위염은 복통, 오심, 구토, 설사, 장폐색 등을 일으킬 뿐만 아니라, 아토피성 피부염, 천식, 위식도 역류, 염증성 장질환 등의 발생과 관련이 있다고 보고되고 있다. 위염 및 다양한 관련 질환에 의한 증상은 공중 근무자들의 임무 수행 능력을 저하시켜 항공기 사고를 발생시킬 수 있는 가능성을 가지고 있다는 점에서 항공의학적으로 매우 중요하며, 실제로 호산구성 위염이나 유문나선균 감염의 치료 여부가 공중 근무자에게 일시적 또는 영구적 비행임무정지를 부과할 수 있는 기준이 되기도 한다. 본 연구에서는 대한민국 공군 장병 환자를 대상으로 내시경을 통해 얻은 위점막 조직 내 호산구수를 측정하고, 이를 위점막 표면의 유문나선균 존재 유무와 관련지어 보았다. 111명 중 20명의 환자에서 한 고배율 시야 당 30개 이상의 호산구가 관찰되었고, 63명의 환자의 위점막 표면에서 유문나선균을 확인하였다. 또한 위점막 내 호산구의 밀도와 유문나선균의 존재 간의 관계는 통계학적으로 유의하였다. 본 연구의 결과는 대한민국 공군 장병을 대상으로 하여 조직 호산구 증가증과 유문나선균의 빈도 및 상호 관계를 최초로 분석했다는 점에서 의의가 있으며, 추후 유문나선균이 어떤 기전으로 위점막 조직 내 호산구의 증가에 관여하는지에 대한 연구를 진행하기 위한 기초 자료로서 활용될 수 있을 것이다.

• Korean journal of applied entomology
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• v.34 no.3
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• pp.224-228
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• 1995

During the survey on spiral nematode (Hoplolaimidae) from Korea, Pararotylenchus blothrotylus Baldwin & Bel, 1981, Rotylenchus feroxcis Eroshenko, 1981 and Scutellonema conicephalum Sivakumar, 1982 were newly recorded from Korea.

• Tunnel and Underground Space
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• v.30 no.4
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• pp.394-403
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• 2020

This technical note describes the calculation method of continuous constant linear velocity Archimedean spiral paths which are applied to the pin-on-disk abrasion test. Approximate constant linear velocity Archimedean spirals have unstable velocities in the very near region of the rotational origin. Thus, in this technical note, the offset distance from the rotational origin was given by using a hollow type rock sample to maintain the constant velocity during the test. Also, to connect the inward and outward spirals continuously, the information of start and end points were input on the next spiral path consecutively. Furthermore, the calculation program was developed to provide convenience for calculating constant linear velocity spirals according to the specimen dimension and abrasion test conditions.

• Journal of the Korea institute for structural maintenance and inspection
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• v.16 no.4
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• pp.89-98
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• 2012

This study estimates the performance of steel spirals according to the compressive strength of the concrete. A total of 24 confined concrete cylinders ($150{\times}300mm$) were cast and tested under monotonic concentric compression. The main test parameters were the yield strength of spiral reinforcements and the compressive strength of the concrete. To effectively evaluate the confinement effect according to the yield strength of steel spirals, the external diameter of steel spirals was designed to be same as the diameter of specimen. The experimental results indicated that the performance of confinement of steel spirals increased as the yield strength of spiral reinforcement increased and the compressive strength of the concrete decreased. Furthermore, existing analytical models were used for predicting the stress versus axial strain relationships of specimens tested in this study. It can be concluded that the accuracy of the analytical models deteriorated as the yield strength of steel spirals and the compressive strength of the concrete increased.

• Journal of the Korea institute for structural maintenance and inspection
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• v.15 no.1
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• pp.103-111
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• 2011

This paper estimated the structural behavior of recycled aggregate concrete confined with spiral reinforcement. The main test parameter was designed to be the type of aggregates and the steel ratio of spirals. A total of 18 specimens were cast and tested in this study. All the specimens had a diameter of 150mm and a height of 300mm. The specimens can be divided into two groups, based on the type of coarse aggregate used. The ratio of spiral reinforcement was varied from 0 % to 1.75%. To measure the axial and lateral deformations of the specimens, a total of six linear variation displacement transducers (LVDTs) were installed at each specimen. Furthermore strain gauges were also attached to the steel spirals to obtain the strain of spiral reinforcements. From the experimental results, the structural performance of recycled aggregate concrete specimens confined by steel spirals was similar to that of natural aggregate concrete specimens regardless of the ratio of spiral reinforcement.

• Magazine of the Korea Concrete Institute
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• v.7 no.2
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• pp.146-154
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• 1995

I n this paper, an experimental research was carried out to investigate the confinement effect of spiral reinforcements in concrete column specimens subjected to t.he concentric axial corn pressive loads. Main variables were the compressive strengths of concrete of 27.2, 62.4 and 81.2 MPa, and the spacings of spirals of 120, 60, 40, 30, 25 and 20mm. and the yield strengths of spir als of 451 and 1375MPa, respectively. For the same volumetric ratio and yield strength of spir als, it was shown that the strength increment of confined concrete was almost same regardless of the strength of unconfined concrete, however, the axial stram at maximum stress was decreas ed with increasing of the compressive strength of unconfined concrete.