• 제목/요약/키워드: 김인후

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소시호탕(小柴胡湯) 위주의 한방 치료로 호전된 구강 작열감 증후군 환자 3명에 대한 증례 보고 (3 Cases of Burning Mouth Syndrome Treated with Sosiho-tang-Based Korean Medicine)

  • 김수진;김연수;지선영;황보민
    • 한방안이비인후피부과학회지
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    • 제34권4호
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    • pp.146-153
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    • 2021
  • Objectives : This study was carried out to investigate the effect of Sosiho-tang on Burning mouth syndrome of female after menopause. Methods : We treated 3 Burning mouth syndrome patients with Sosiho-tang-Based Korean Medicine. We evaluated the severity of pain and heat by using the Visual Analogue Scale(VAS). Results : After the treatments, all patient's objective score of Burning mouth syndrome was remarkably decreased. Conclusions : This study suggests that Sosiho-tang is effective against Burning mouth syndrome of female after menopause.

하서(河西) 김인후(金麟厚)의 독서관에 관한 연구 - "하서전집"의 인용문헌 분석을 중심으로 - (A Study on Kim Inhue's View of Reading: Through the Analysis of Reference Books in Haseo-Chunjib)

  • 안현주
    • 한국도서관정보학회지
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    • 제39권3호
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    • pp.479-500
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    • 2008
  • 이 연구는 "하서전집"의 인용문헌 분석을 통해 김인후의 독서관을 고찰하였다. 그 결과 최소한 123종의 책을 독서했으며, "사서삼경", "사기", "한서", "장자", "고문진보", "초사", "문선"을 가장 많이 인용하였다. 김인후는 16세기 선비들이 보여주는 공통적인 독서범주를 뛰어넘은 다양한 독서, 시대상에 구애받지 않은 자유로운 독서를 했음을 알 수 있다. 그의 독서관은 성리학의 경서를 중요시 여겼으며 또한 다양한 독서를 통하여 실생활에 유익한 지식을 얻음과 동시에 방대한 저술의 바탕을 마련하였다.

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NF-𝜅B억제를 통한 청심양격산(淸心凉膈散)의 항염증 효과 (Anti-inflammatory Effects of Cheongsimyanggyeok-san via NF-𝜅B Inhibition)

  • 김난이;김연수;지선영;황보민
    • 한방안이비인후피부과학회지
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    • 제32권2호
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    • pp.11-23
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    • 2019
  • Objectives : The purpose of this study is to investigate the anti-inflammatory effect of Cheongsimyanggyeoksan(CYS) water extract in vitro and in vivo. Methods : To evaluate the anti-inflammatory effect of CYS, Raw 264.7 cells were pretreated with $3-300{\mu}g/m{\ell}$ of CYS for 1h, and then exposed to $1{\mu}g/m{\ell}$ of LPS. The cell viability was detected by MTT assay. Productions of nitric oxide(NO) and pro-inflammatory cytokines were measured in culture media. Protein levels of inducible nitric oxide synthase(iNOS) and Nuclear factor-${\kappa}$B($NF-{\kappa}B$) were determined by immunoblot analysis. The effect of CYS on acute inflammation in vivo was evaluated thorugh measurment of carrageenan-induced paw edema. Results : In vitro study, cell viability assay CYS treatment of $3-300{\mu}g/m{\ell}$ has no cytotoxicity in Raw 264.7 cells. LPS-induced NO production was significantly inhibited by pretreatment with $30-300{\mu}g/m{\ell}$ of CYS. Production of interleukin-6, -$1{\beta}$ and tumor necrosis factor-${\alpha}$ by LPS were significantly decreased by CYS pretreatment. CYS reduced LPS-mediated iNOS expression. Moreover, CYS significantly induced $I-{\kappa}B{\alpha}$ expression and reduced $NF-{\kappa}B$ expression. In vivo study, CYS significantly reduced the increases of paw swelling. Conclusions : These results suggest the clinical basis of CYS for the treatment of inflammatory diseases.

COVID-19 전후 단일 한방병원 및 한방 안이비인후피부과 외래 환자들에 대한 비교 분석 (Comparative Analysis of Outpatients Visiting Korean Medicine Hospital and Department of Ophthalmology, Otolaryngology & Dermatology of Korean Medicine Pre- versus Post- COVID-19)

  • 김병현;김준동;서광일;김규석;남혜정;김윤범
    • 한방안이비인후피부과학회지
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    • 제36권1호
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    • pp.96-109
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    • 2023
  • Objectives : The objective of this study is to predict how future infectious diseases will affect healthcare utilization patterns within korean medicine hospitals and, specifically, departments of ophthalmology, otolaryngology and dermatology of Korean medicine. Methods : We retrospectively analyzed medical records of patients who visited Kyung Hee University Korean Medicine Hospital during Pre COVID-19(from March 1st, 2018 to Feb 29th, 2019) and Post COVID-19(from March 1st, 2019 to Feb 28th, 2022). The data was analyzed by visit type and diagnosed disease code. Results : 1. After the COVID-19 break-out, the number of first visit patients increased but those of revisit patients, total patients, and revisit/first visit ratio decreased in all departments. 2. In Kyung Hee University Korean Medicine Hospital, the decrease rate of the number of total patients diagnosed with diseases of respiratory system(J00-J99) was the highest, while that for diseases of circulatory system(I00-I99) was the lowest. 3. In the department of Ophthalmology and Otolaryngology of Korean Medicine, the decrease rate of the number of total patients with nose disease was the highest, followed by eye disease and ear disease. 4. In the department of Dermatology of Korean Medicine, the number of total patients with dermatitis remained consistent, while the number of total patients with skin appendage disease showed relatively high decrease rate. Conclusions : Severe or chronic diseases showed relatively low decrease rate of the number of total patients. While mild diseases or diseases with high probability of exposure to COVID-19 infection during treatment showed high decrease rate of the number of total patients.

하서(河西) 김인후(金麟厚) 상의 형성과 그 시대적 맥락 - 생애자료에 대한 비교변증을 통해 - (The Meaning of Evaluating Ha-Seo in the Historical Context - Through demonstration based on comparison of materials related to lifetime)

  • 김남이
    • 동양고전연구
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    • 제59호
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    • pp.57-92
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    • 2015
  • 이 논문은 하서 김인후가 사후에 조선 성리학의 정통 학맥을 계승하는 존재로 위상이 부여되고 추숭되는 과정을 추적하였다. 그리고 이와 같은 형상화의 과정을 근거로 과거 인물의 생애를 다룬 다양한 자료가 상호간에 어떤 방식으로 영향을 주거나 배제하면서 인물형상화의 과정을 거치는지 확인해 보고자 하였다. 하서의 어린 시절 생애는 김인후와 군주 인종의 굳건한 관계를 부각하기 위해 새로이 배치되었다. 김인후는 당시 사림들에게는 깊은 상처이자 풀어야 할 시대적 과제로 인식되고 있던 기묘사림의 복권이라는, 그 당시 가장 중요하고도 첨예한 문제를 제기한 사람이고, 인종은 기묘사림의 복권을 실현한 군주였기 때문이다. 이것은 무엇에도 흔들리지 않는 굳건한 절개와 충심을 가진 선비로서의 하서의 상을 세우는 데 결정적인 기여를 했다. 조선후기에서는 중앙 조정의 서인과 군주 정조의 주도 하에 하서에 대한 추숭이 이루어졌다. 우선 17세기는 서인들이 김인후의 생애를 다룬 자료들을 다방면으로 수정하고, 김인후의 문집을 교정하여 간행했다. 이것은 당시 서인들이 추진하고 있던 서인계열의 학통 수립, 학문의 정통성 확보라는 목표 하에서 이루어진 것이었다. 그에 따라 율곡 이이를 비롯한 서인계 학자들에 대한 추숭과 병행되었다. 마지막으로 18세기에 이르러 하서는 문묘에 종향되면서, 조선에서 가장 앞선 성리학자이자 해동정학(海東正學)으로서의 위상을 부여받았다. 그 과정에서 우리는 정조가 군왕으로서 정치적으로 한 국가의 수장일 뿐만 아니라, 한 국가의 정통의 학문에 대한 책임을 자부하는 사표(師表)로서 자기의 위상을 확고히 하려는 욕망을 읽을 수 있다.

화폐상 습진의 한의학적 치료에 대한 국내 임상 논문 분석 (Review of Korean Medicine Treatments for Nummular Eczema in Korean Journals)

  • 김혜경;김정윤;김순아;이지원;임승환
    • 한방안이비인후피부과학회지
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    • 제32권4호
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    • pp.116-129
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    • 2019
  • Objectives : The purpose of this study is to analyze the trend of Korean medical treatments on nummular eczema. Methods : Based on OASIS, NDSL, RISS, KTKP, KISS, KCI with the keyword 'Nummular Eczema'. published in 2000-2019.08.31, total 11 studies have been found and analyzed. Results : Among 11 studies, 21 cases were selected. Herb medicine, acupuncture, pharmacopuncture, externals, other treatments were used as treatment for nummular eczema. All of research which selected have reported that the Korean medical treatment was effective. Conclusions : According to the results, Korean medical treatments can be effective treatment for nummular eczema. Further clinical studies are expected using evaluation methods to analyze the results and to establish high level of evidence.

소아 비인강에서 발생한 점액표피양암종 1례 (A case of nasopharyngeal mucoepidermoid carcinoma in a 5 year-old female patient)

  • 윤소연;김미주;김민범;홍현준;송기재
    • 대한두경부종양학회지
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    • 제34권2호
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    • pp.89-92
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    • 2018
  • Malignant salivary gland tumors only represent 0.08% of all childhood tumors. Especially, nasopharyngeal mucoepidermoid carcinoma(MEC) in pediatric age is an extremely rare malignancy. We hereby report a case of nasopharyngeal MEC in 5 year-old female patient. The patient underwent the complete removal of the tumor by endonasal endoscopic approach. Adjuvant postoperative radiotherapy was not considered. After 3.5 years of follow-up, there are no sign of recurrence and metastasis. Minor salivary gland tumor must be considered as a differential diagnosis of angiofibroma in nasopharynx in pediatric age. To our knowledge, the case we describe is the third case of nasopharyngeal MEC in pediatric age reported in literature.

네트워크 약리학을 활용한 심상성 건선에 대한 인진호(茵蔯蒿)의 잠재적 작용 기전 탐색 연구 (A Network Pharmacology-based Study to Explore the Potential Mechanism of Artemisia capillaris Thunb. for Psoriasis Vulgaris)

  • 김준동;서광일;김병현;이한림;김규석;김윤범
    • 한방안이비인후피부과학회지
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    • 제35권3호
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    • pp.15-24
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    • 2022
  • Objectives : The purpose of this study is to investigate the potential mechanism of Artemisia capillaris Thunb. for psoriasis vulgaris. Methods : We conducted the network pharmacological analysis. It contains the process that search the compounds of the herb, the target proteins of the compounds, related genes of psoariasis vulgaris and the pathway/terms of the common protein lists between psoriasis vulgaris and Artemisia capillaris Thunb.. Results : 13 compounds and 30 protein targets of Artemisia Capillaris Herba were searched. And 997 psoriasis-related genes were searched. The common proteins were 11, and the core genes were 3; AKT1, CASP3, MAPK8. The related pathway/terms of 11 proteins were analyzed. ω-hydroxylase P450 pathway(60%), nitric oxide(NO) biosynthetic process(20%) were resulted. Also, 19 proteins of Artemisia Capillaris Herba were analyzed, and sterol homeostasis(78.95%), sterol biosynthetic process(15.79%), Type 2 diabetes mellitus(5.26%) were resulted. Conclusion : The Artemisia Capillaris Herba can potentially act through the ω-hydroxylase P450 pathway and nitric oxide(NO) biosynthetic process for psoriasis. Also, the metabolism of sterol biosynthesis and homeostasis can be involved in a roundabout way for psoriasis.