• Proceedings of the Optical Society of Korea Conference
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• 2009.02a
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• pp.387-388
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• 2009

Biophotonics is an emerging area in a fusion of biology and photonics, especially in advanced bioimaging, optical biosensors, photomodulation, and biochip optical read-out, and optical manipulation. This emerging area also creates many opportunities for interdisciplinary study of biology and photonics. Micro-Electro-Mechanical-System(MEMS) is an attractive technology in miniaturizing sensors and actuactors. For last decade, it has contributed to the development for active and passive small and integrated optical components in optical communication. Recently, this technology is also merging into biology for high sensitive biosensing and high resolution and fast bioimaging in small form factor. In this talk, some key advantages of small optical components and recent biophotonic MEMS achievement will be discussed for miniaturized advanced biophotonic systems.

• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 2000.05a
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• pp.292-297
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• 2000

This paper proposes a new concept of coordinating green time which controls 10 traffic intersection systems. For instance, if we have a baseball game at 8 pm today, traffic volume toward the baseball game at 8 pm today, traffic volume toward the baseball game will be increased 1 hour or 1 hour and 30 minutes before the baseball game. At that time we can not predict optimal green time Even though there have smart elctro-sensitive traffic light system. Therefore, in this paper to improve average vehicle speed and reduce average vehicle waiting time, we created optimal green time using fuzzy rules and neural network. Computer simulation results proved reducing average vehicle waiting time which proposed coordinating green time better than electro-sensitive traffic light system dosen't consider coordinating green time.

• 한국태양에너지학회:학술대회논문집
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• 2009.11a
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• pp.291-296
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• 2009

This paper investigates the energy saving potentials of a dedicated outdoor air system (DOAS) applied to a highrise apartment building. As for a typical $132-m^2$ apartment unit, two different HVAC systems; centralized DOAS-Ceiling Radiant Cooling Panel and decentralized Energy Recovery Ventilator-Packaged Air Conditioner were installed. Transient behavior and control characteristics of each system were modeled numerically using a commercial equation solver program, and annual cooling coil load and heating load reduction potentials were compared. The research shows that DOAS-Ceiling Radiant Cooling Panel system can reduce the cooling coil load over 21% annually compared with the current Energy Recovery Ventilator-Packaged Air Conditioner pair. In addition, over 40% of annual ventilation heating load can be reduced by use of DOAS.

• 한국태양에너지학회:학술대회논문집
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• 2009.11a
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• pp.285-290
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• 2009

The main thrust of this paper is to investigate acceptable supply air conditions of a dedicated outdoor air system (DOAS) for highrise apartment buildings. As for a typical $132-m^2$ apartment unit, it was assumed that centralized DOAS-Ceiling Radiant Cooling Panel was installed. Transient behavior and control characteristics of each system were modeled numerically using a commercial equation solver program. The optimized dew point temperature of the DOAS was discussed on the basis of the ASHRAE standard 62.1-2007 and the current Korean ventilation standard for apartments. It was found that the optimized dew point temperature of the DOAS supply air accommodating total latent load of a space is $11-12^{\circ}C$ and the appropriate supply air temperature of the DOAS is $11-12^{\circ}C$ in cooling period and neutral temperature of $18-20^{\circ}C$ in intermediate period.

• Journal of the Korea Society of Computer and Information
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• v.28 no.10
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• pp.113-121
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• 2023

Network pharmacology in traditional Korean and Chinese medicine studies the molecular and biological aspects of herbal medicine using computational methods. Despite variations in databases, techniques, and criteria, most studies follow similar steps: constructing herb-compound networks, compound-target networks, and target interpretation. To ensure efficient and consistent analysis in herbal medicine network pharmacology, we designed and implemented a common analysis pipeline. We showed its reliability with existing databases. The proposed system has a potential to facilitate network pharmacology analysis in traditional medicine, ensuring consistent analysis of various herbal medicines.

• Physical Therapy Korea
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• v.2 no.2
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• pp.1-8
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• 1995

이 논문의 주목적은 정상인을 대상으로 각기 다른 3가지의 (체중의 1.5 %, 3.0 %, 9.0 %) 부하를 통해서 자세의 불균형을 유발시켰을 때 나타나는 postural movement patterns을 기술하기 위한 연구이다. 연구대상의 허리중심에 체중부하를 주어 균형이 뒤로 이동하게 하여, surface EMG(표면 근전도)를 통하여 Tibialis anterior(Ta), Gastrocnernius(Gc), Quadriceps femoris(Qc), Hamstring(Ha), Rectus abdominalis(Ab)와 Paraspinalis(Pa) 근육들의 motor recruitment pattern(운동회집형태)를 측정하였다. 그리고 비디오 촬영은 고관절, 슬관절, 족관절의 움직임을 보기 위해 사용하였다. 특히 근전도 (EMG)는 자세반응 검사에 있어 첫 근반응(근수축) 경과시간(FR)과 분절간격간의 (ID)시간을 조사하는데 사용되었다. 이 연구의 결과는 4가지 중요한 사실을 전해주고 있다. 첫 번째로서, 연구대상자에게 체중의 1.5 %의 부하를 적용하였을 때 Ta가 가장 먼저 수축을 시작하였고(FR:$88{\pm}19.4$ ms) 발목과 대퇴사이의 분절 간격간(ID)의 평균은 +9.3 ms였다. 또한 족관절의 변화가 가장 뚜렷하여 Nashner(1985)의 족기전을 뒷받침하고 있다. 둘째로는 연구대상자에게 체중의 3.0 %의 부하를 주었을 때 Qc와 Ab근육이 원위부에서 근위부 순서로 수축하였고, 첫 번째 근육수축시간은 ($82{\pm}39.2$ ms)였다. 그리고 이때 분절간격의 평균은 +8.3ms 이였고 Ta는 거의 반응하지 않았다. 족관절과 슬관절에 비해 고관절의 변화가 가장 현저하게 나타났고, 이 또한 Nashner의 고관절 기전과 같은 현상을 보였다. 셋째로 연구 대상자에게 체중의 9.0 % 부하를 허리에 적용하였을 때 근수축은 근위부에서 원위부 순서를 이루어졌다. 즉 Ab,Qc, Ta, Ps순으로 근수축 되었다. Ab가 처음으로 수축하여 첫 반응(FR)은 $73{\pm}3.2$ ms 이였고 슬관절과 고관절의 변화가 가장 뚜렷하였다. 넷째로 연구 대상자에게 체중의 9.0 %부하를 적용하였을 때, 균형을 잡기 위해 뒷걸음치는 것이 관찰되었고 이때 근수축 순서는 Ta,Ab.Ps,Qc,Hs였다. 이 결과는 Nasher의 결과와 불일치하였다. 이상과 같은 결과에서 연구대상자의 자세운동형태(postural movement patterns)는 각기 다른 부하 정도와 시간에 따라 합성적으로 이루어지는 것으로 보여졌다. 특히, 자세운동형태는 부하의 적용위치와 연구대상자의 최근의 경험에 영향을 받은 것으로 밝혀졌다. 결론적으로 말하면 자세운동형태는 중앙신경계의 제한적(한정적) 명령 시스템에 의해서 움직임(movement)이 발생하기 전에 조직된다는 Nashner의 가설을 뒷받침하였다.

• Journal of Life Science
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• v.19 no.6
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• pp.836-838
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• 2009

Tissue plasminogen activator (tPA) is very useful for dissolving the clots of blood, however, the use of tPA is limited to only 3-5% of ischemic stroke patients because of the narrow therapeutic time windows and negative side effects. Previous evidences suggest that limitation of tPA in thrombolytic therapy may be related to the upregulation of MMPs. However, little is known about the regulatory mechanism. In this study, we examined the role of tPA on MMP upregulation in rat neuronal cells. tPA (5 ${\mu}g$/ml) increased MMP-9 levels of neuronal cells in a time dependent manner. Hypoxia/reoxygenation amplified tPA-induced MMP-9 levels significantly. Pretreatment with JNK inhibitor SP600125 reduced the MMP-9 response. These results suggest that tPA can upregulate MMPs in neuronal cells and that JNK kinase may be involved.

• Journal of Biosystems Engineering
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• v.21 no.3
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• pp.325-335
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• 1996

Visual features are crucial for monitoring the growth state, indexing the drying performance, and grading the quality of oak mushrooms. A computer vision system with neural net information processing technique was utilized to quantize quality factors of a dried oak mushrooms distributed over the cap and gill sides. In this paper, visual feature extraction algorithm were integrated with the neural net processing to deal with various fuzzy patterns of mushroom shapes and to compensate the fault sensitiveness of the crisp criteria and heuristic rules derived from the image processing results. The proposed algorithm improved the segmentation of the skin features of each side, the identification of cap and gill surfaces, the identification of stipe states and removal of the stipe, etc. And the visual characteristics of dried oak mushrooms were analyzed and primary visual features essential to tile quality evaluation were extracted and quantized. In this study, black and white gray images were captured and used for the algorithm development.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.7
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• pp.607-615
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• 2016

This study concerns the transmission of energy and data using induced electromotive force. Due to the requirements of weapon systems, most arms are kept in an armory for a very long time before being used. During this time, the reserve battery, which serves mostly as a power supply for the electronic fuze, can be degraded, thus causing problems when it is actually needed. We attempt to solve the various problems associated with the old fuze system caused by long-term storage by using the 'induction power' transmitted from another device just before its operation, instead of using 'built-in power'. We tried to find the best carrier frequency to communicate with the system by induced electromotive force. Also, we changed the communication method for transmitting the 'induction power' from 'FM/AM modulation' to 'Duty ratio modulation', which can transmit a large amount of data in a short time. Through experiments, it was demonstrated that the induction coil can replace the reserve fuze's battery without any problem, thus confirming the possibility of using an induction coil as the power supply source of the electronic fuze.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.14 no.1
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• pp.64-80
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• 2003

Although obsessive-compulsive disorder(OCD) affects children, adolescents, and adults whether its juvenile(dhild and adolescent) and adult forms are different subtype of a disorder remains unknown. But there are increasing findings that suggest that juvenile OCD may be unique subtype of the disorder. One proposed subtype is the childhood OCD associated with high comorbidity of tic disorder and increased familial loading for OCD or tic disorder. The other proposed subtype is the childhood OCD and/or tic disorder occuring in association with streptococcal infection(PANDAS). These two subtypes of OCD are unlikely to respond to SSRI due to possible different pathphysiological mechanism. So this paper reviews the characteristics of OCD and therapeutic approaches for treatment resistant OCD in childhood and adolescence. Considering the likely heterogeneity of OCD, the possibility that juvenild OCD may be a variant of the disorder can have important clinical and scientific implications because it may further our understanding of this disorder, its etiology, and perhaps its treatment.