• Journal of Biomedical Engineering Research
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• v.24 no.6 s.81
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• pp.523-531
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• 2003

We developed a PC-based 8-channel electrical stimulation system for transcutaneous functional electrical stimulation (FES), and applied it to FES exercise and paraplegic walking. The PC program consists of four parts: a database, a stimulation pattern generator, a stimulus parameter converter, and an exercise program. The stimulation pattern can be arbitrarily generated and edited by using the mouse on the PC screen, and the resulting stimulus parameters arc extracted from the recruitment curves, and transmitted to the 8-channel stimulator through the serial port. The stimulator has nine microprocessors: one master and eight slaves, Each channel is controlled by the slave microprocessor, and is operated independently. Clinical application of the system to a paraplegic patient showed significant increase in the knee extensor torque, the fatigue resistance, and the leg circumference, The patient can now walk about 50 meters for more than 2 minutes.

• The Korean Journal of Physiology
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• v.22 no.1
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• pp.101-109
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• 1988

최근에 마취한 흰쥐에서 중뇌망상체를 전기적으로 자극하면 췌장의 외분비 기능이 증가하며 이러한 결과는 망상체의 자극으로 인하여 교감신경계의 활성도가 상승하기 때문이라는 보고가 있다. 한편 교감신경계의 활성도가 상승할 경우 교감신경계의 전달 물질인 catecholamine이 교감신경 종말 뿐만 아니라 부신수질에서도 유리된다고 알려져 있다. 그러므로 본 연구에서는 중뇌망상체의 자극으로 인하여 췌장의 외분비 기능이 증가함에 있어 교감신경계가 중요한 역할을 담당하는지를 확인하고, 이때 부신수질이 관여하는가를 알아보고자 하였다. 마취한 흰쥐에게 atropine (1mg/kg) 또는 reserpine (5mg/kg)을 투여하거나 또는 부신을 적출한 다음 중뇌망상체를 전기 자극하면서 췌장액을 채취하였다. 사용한 전기자극의 매개변수는 1.3V, 40Hz, 2msec이었다. atropine과 reserpine을 투여하면 마취한 흰쥐의 자발적 췌장액 분비량과 단백질 분비량은 모두 유의하게 감소하였으나 부신을 제거하면 췌장액 분비량에는 이렇다할 변동이 없는 반면에 단백질 분비량은 유의하게 감소하였다. 중뇌망상체를 전기자극하면 췌장액 분비량과 단백질 분비량 모두가 유의하게 증가하였다. 이러한 망상체의 자극효과는 atropine 전처치에 의하여 이렇다할 영향을 받지 않았으나 reserpine 전처치에 의하여 소실되었다. 그러나 부신을 적출하면 망상체 자극에 의한 췌장액 분비량의 증가는 유지되는 반면에 단백질 분비량의 증가는 소실되었다. 한편 미주신경을 절단한 흰쥐에서 중뇌망상체를 자극하는 동안에 경동맥의 수축기 및 이완기 혈압이 상승하였는데 이러한 망상체의 자극효과도 reserpine의 투여에 의하여 유의하게 감소되었다. 본 실험의 결과를 종합하여 보면 마취한 흰쥐에서 중뇌망상체의 자극은 교감신경계를 활성화시켜 췌장액 분비량과 단백질 분비량에 촉진적인 영향을 미치며, 이때 활성화된 교감신경계는 부분적으로 부신을 경유하게 췌장의 단백질 분비에 촉진적인 영향을 미치는 것으로 생각된다.

• Journal of Biomedical Engineering Research
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• v.25 no.2
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• pp.151-156
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• 2004

The purpose of this study was to develop EMG triggered FES system for restoration of upper extremity function in chronic hemiplegic patients and to identify the optimal location of electrode application for the EMG triggered FES system which produces effective muscle contraction and detects EMG activity for extension in the wrist and finger joints. The stimulus system was composed of EMG measuring component, constant current component and the program for muscle contraction by EMG triggered FES and passive FES. Parameter of electrical stimulation was 35 ㎐ in frequency, 150 ${\mu}\textrm{s}$ in pulse width and symmetric bi-phasic wave. In 15 hemiplegic patients, EMG triggered FES was applied to the proximal half of forearm which was divided into 12 areas. The most sensitive area for measuring EMG activities during extension of the wrist and fingers was area 4, 5 and the optimal location of electrical stimulation for producing extension of the wrist and fingers was area 4, 5, 7, 8. These results suggest that the area 4 and 5 was considered as the most optimal location of electrode application for measuring EMG activities as well as producing extension of the wrist and fingers by EMG triggered FES system.

• Therapeutic Science for Rehabilitation
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• v.7 no.1
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• pp.63-77
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• 2018

Objective : The purpose of this study was to investigate the effects of task-oriented training with functional electrical stimulation on hand function in incomplete cervical cord injury. Method : The subjects of the study were 3 adults diagnosed as incomplete cervical cord injury. The design of this study was ABA single-subject research design to compare dominant hand function of before and after intervention and detect individual effects. The experiment consisted of 30sessions, in which baseline process A1 and A2 were implemented 5 sessions each for 10sessions. Intervention B was implemented 20 sessions. The dependent variable was converted to the change of hand function every session, and Canadian Occupational Performance Measure (COPM), Jebsen-Taylor Hand Function Test(JTHFT), Wolf Motor Function Test(WMFT) were selected for outcome measurements. Result analysis was suggested through visual analysis using a graph and comparison of pre, post and follow-up intervention measurements. Results : As a result, the quality and quantity of dominant hand function increased during intervention B compared to the baseline A1 for all subjects. Baseline A2 was also maintained without training. Additionally, JTHFT, WMFT and COPM scores demonstrated improvement and maintain. The follow up JTHFT and WMFT showed increased required time on all subjects and decrease or maintain task performance and satisfaction in COPM. Conclusion : The task-oriented training with function electrical stimulation in this study has been positive effects on hand function and task performance and satisfaction.

• Korean Journal of Cognitive Science
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• v.33 no.1
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• pp.51-75
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• 2022

Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation that is able to alter neuronal activity in particular brain regions. Many studies have researched how tDCS modulates neuronal activity and reorganizes neural networks. However it is difficult to conclude the effect of brain stimulation because the studies are heterogeneous with respect to the stimulation parameter as well as individual difference. It is not fully in agreement with the effects of brain stimulation. In particular few studies have researched the reason of variability of brain stimulation in response to time so far. The study investigated individual variability of brain stimulation based on circadian rhythm and chronotype. Participants were divided into two groups which are morning type and evening type. The experiment was conducted by Zoom meeting which is video meeting programs. Participants were sent experiment tool which are Muse(EEG device), tdcs device, cell phone and cell phone holder after manuals for experimental equipment were explained. Participants were required to make a phone in frount of a camera so that experimenter can monitor online EEG data. Two participants who was difficult to use experimental devices experimented in a laboratory setting where experimenter set up devices. For all participants the accuracy of 98% was achieved by SVM using leave one out cross validation in classification in the the effects of morning stimulation and the evening stimulation. For morning type, the accuracy of 92% and 96% was achieved in classification in the morning stimulation and the evening stimulation. For evening type, it was 94% accuracy in classification for the effect of brain stimulation in the morning and the evening. Feature importance was different both in classification in the morning stimulation and the evening stimulation for morning type and evening type. Results indicated that the effect of brain stimulation can be explained with brain state and trait. Our study results noted that the tDCS protocol for target state is manipulated by individual differences as well as target state.

• Journal of Biomedical Engineering Research
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• v.20 no.2
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• pp.183-190
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• 1999

The purpose of this study was to develop a portable and convenient closed-loop contrel type electrical stimulator for patients with foot drop. This system restores walking movement as well as prevents from atrophy or necrosis of lower limb muscles and increases blood circulation in hemiplegic patients caused by traffic accident, industrial disaster or stoke. This system detects the changes of the ankle joint angle during walking, and then controls the stimulus intensity automatically to maintain the programmed level of the ankle joint angle. Also, this automatic system controls the stimulus intensity which is affected by increased electrode impedance resulting from long time use. The system detects the joint angle by an optical sensor and includes modified PID control which adjusts the stimulus intensity if the joint angle deviates from the preset value. Stimulus parameters are 30~80 volt, 40 Hz, and 0.2 ms. The system was applied to five hemiplegic patients for 42 days. Duration of stimulation was 15 min/day for the first week and then the duration was gradually increased to 30, 60, 90 and 120 min/day. The muscle force was increased up to 29.7%, muscle fatigue was decreased compared with the level before stimulation and the pattern of locomotion was improved. These results suggest that the electrical stimulator with closed-loop control type is more convenient and effective in restoration of locomotion of patients with foot drop than open-loop system.

• 제어로봇시스템학회:학술대회논문집
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• 2000.10a
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• pp.245-245
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• 2000

후각기는 후각신경과 삼차신경의 기능을 객관적이고 정량적으로 검사할 수 있는 기기로, 객관적으로 인정받을 수 있는 후각기의 제작에는 많은 어려움이 있기 때문에, 현재까지 후각신경과 삼차신경의 기능을 정확하게 측정할 수 있는 방법이 없었다. 그러나, 산업이 발달하고 공해가 더욱 심해질수록 후각의 변화가 생기고, 비강 내 질환이나, 공해물질 등에 의해 삼차신경이 민감한 반응을 일으키므로, 앞으로는 이 신경들의 측정이 중요할 것으로 여겨진다. 또한 각종 산업분야에서 이제까지 사람의 미각이나 후각에 의존하여 제품을 생산해오던 방법을 변화시켜 객관적인 수치를 이용하여 제품을 생산할 수 있다. 따라서 이번 연구에서는 사람이나 동물에게 다양한 후각물질을 원하는 정확한 농도로 투여하는 기기로, 온도와 습도를 사람의 신체 조건과 동일한 공기와 혼할하여 원하는 정확한 농도(ppm)의 후각 자극을 만들어 mass flow controller와 solenoid valve를 이용하여 square-shape의 자극모양이 되도록 한 후, 피검자에게 자극하여 전기생리학적 반응을 얻는 기기를 개발하였다.

• Food Science of Animal Resources
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• v.22 no.3
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• pp.234-239
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• 2002

The use of electrical stimulation in the red meat processing has been inconsistent and the mechanism(s) associated with the improvement of meat quality in electrically stimulated carcass has been disputed. This may reflect an incomplete knowledge of how to optimise the technology and also mirrors the existence of unknown factors. Although it is well established that the stimulation treatment increases the rate of post-mortem glycolysis, other biochemical and biophysical effects have been implicated with the use of this technology. The classical view that stimulation prevents muscle from shortening excessively during rigor development has been expanded to include the possibility that it also results in physical disruption of muscle structure and early 'turn-on' of tenderizing process. However, the interaction of these effects with the acceleration of the rate of proteolysis through activation of the calpain pretense system has not been comprehensively unravelled. This mini-review attempts to examine the current theories about the effect of stimulation on post-mortem muscle.

• Journal of Digital Convergence
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• v.17 no.12
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• pp.319-327
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• 2019

The muscle activity and balance ability of the acute stroke patient has been checked by the functional electrical stimulation using biofeedback fusion postural control training in this study. Functional electrical stimulation using biofeedback fusion postural control training have been implemented on 15 trainees and general biofeedback fusion postural control training have been implemented on another 15 trainees for 30 minutes at 5 times per week during 8 weeks, and vastus lateralis, vastus medialis, rectus femoris and biceps femoris have been measured using the biceps femoris to evaluate the muscle activity of the lower extremity. The moving surface area, whole path length and limited of stability have been measured using biorecue to measure the balance ability. There was statistically meaningful difference on the vastus lateralis, vastus medialis, rectus femoris and biceps femoris in the muscle activity of the lower extremity and there was statistically meaningful difference on surface area, whole path length and limited of stability in the balancing ability. Based on above, it is realized that the functional electrical stimulation using biofeedback fusion postural control training is more effective than the general biofeedback fusion postural control training on the improvement of the muscle activity of the lower extremity and the balance ability.

• Journal of rehabilitation welfare engineering & assistive technology
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• v.8 no.1
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• pp.57-66
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• 2014

This study has been conducted to identify the current status and practices of electrical stimulation for patients with dysphagia in Korea. Main goal of the study is to find evidences of developing and distributing a quality indicator and organized performance exam. This study analyzed 50 survey questionnaires given to clinical professionals in upper-scale general hospitals, university hospitals, nursing homes and professional rehabilitation hospitals. The survey sent out and collected by E-mails or interviews from August 21, 2013 to November 10, 2013. Most of the hospitals showed lack of using a quality indicator and organized performance exams in device maintenance, pre-operational tests and post-operational tests. It is strongly recommended to develop a standardized guideline of a higher quality indicator and organized performance exam in using neuromuscular electrical stimulator for patients who are suffering from dysphagia.