• Proceedings of the Korean Institute Of Construction Engineering and Management
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• 2007.11a
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• pp.151-156
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• 2007

2006년부터 VE 대상프로젝트가 확대되고, 기본설계와 실시설계단계에 각 1회씩 설계VE를 적용토록 규정되어 설계단계별로 VE가 각각 적용되는 프로젝트가 늘어나고 있다. 그리고 원가절감과 성능향상으로 프로젝트 가치를 높인 설계VE 사례도 많아지고 있다. 하지만 기본설계와 실시설계단계의 조건에 적합한 VE 수행방안에 대한 연구가 미진하고 참여자들의 경험과 이해가 부족하여 단계별 설계VE를 효율적으로 수행하는데 많은 어려움이 있다. 본 연구에서는 기본설계단계와 실시설계단계로 나누어 VE를 수행한 실무사례를 분석하여 기능정의와 아이디어 창출간의 연관관계 및 각 설계단계에서 기능정의를 수행할 때 발생하는 문제점을 도출하였다. 문제점을 해결하고 효과적인 설계VE를 수행하기 위하여 다음과 같은 개선방안을 제시하였다. 첫째, 설계프로세스의 흐름에 맞추어 기본설계에는 공간기능에 대하여하고 실시설계에는 부위에 대하여 기능정의를 수행한다. 이때 상위의 레벨에는 하위의 레벨의 기능정의가 연계되는 기능분류체계 (FBS : Function Breakdown Structure)를 제안하였다. 둘째, 기본설계와 실시설계단계의 기능정의를 수행하는 프로세스 (FDP : Function Definition Process)를 제안하였다. 셋째, 실시설계단계에서는 부위별 요구 성능 평가 매트릭스 (EFM : Element Function Matrix)를 적용하여 기능정의와 아이디어 창출이 연계되도록 하였다. 설계VE의 주요 부분인 기능정의 과정에 대한 문제점을 도출하여 해결방안을 제시함으로써, 보다 효과적인 설계VE의 수행을 기대할 수 있다.

• Korean Journal of Construction Engineering and Management
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• v.12 no.5
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• pp.12-22
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• 2011

Design value engineering (VE) has been performed in many construction projects according to the changes in the construction for most of the VB function analysis that performed, are problems that focus on function analysis and generating ideas based on individual experience of VE team member than generating ideas and value improvement of systematic function analysis. This may be due to the quotation of previously performed function analysis data, general function analysis, and abstract function definitions that do not cite the concrete characteristics of each facility. Therefore, in this study, the proposed cases from the existing design VE workshops, the current conditions of the connection between functions and ideas and of the idea categorization by building part were studied to determine why functions and ideas are not connected, and to propose pertinent improvement directions. on a performance-based function categorization system by building part that can provide the logical connection between functions and ideas in the function definition/categorization and function arrangement phases in the function analysis phase, the most important phase in VE activities, was developed by reflecting the required performance and functions for each part of the facility.

• Proceedings of the Korean Information Science Society Conference
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• 2003.10b
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• pp.730-732
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• 2003

의료영상정합을 통해서 이상징후 발현시점과 소멸시점의 기능영상을 비교함으로써 기능이상부위를 판별하는 것은 질환의 진단에 매우 유용하다. 본 논문에서는 기존 변화시점간 기능영상 감영법이 정확한 소멸시점에서의 영상 취득이 어려움으로 인해 정확도가 떨어질 우려가 있는 점을 개선하고자 뇌 혈류이상을 나타내는 뇌기능영상인 SPECT의 변화시점 기능이상부위 추출을 위하여 정상인집단 영상의 비선형 영상정합기법과 영상평균화를 통해 뇌기능영상 템플릿을 구축하였다. 또한 이를 기반으로 영상감영을 수행함으로써 간질환자의 발작중(ictal) SPECT 뿐만 아니라 발작간(interictal) SPECT에서도 뇌혈류의 이상을 정확히 분석할 수 있는 3차원 추출가시화 방법을 제시하였다.

• Horticultural Science & Technology
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• v.30 no.4
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• pp.449-462
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• 2012

The objectives of this study were to measure the range of motion for joints and muscle activation of upper limb for flower arrangement tasks for physical rehabilitation and to test horticultural therapy programs using flower arrangement tasks for improving upper limb function of the patients with stroke. Major flower arrangement tasks were classified with eight tasks (cutting 1, thick stem; cutting 2, thin stem; fixing 1, long stem; fixing 2, short stem; rolling a leaf; bending 1, thick stem; bending 2, thin stem; and winding, using a wire) based on the occupational analysis. When eight male university students (mean age $24.1{\pm}2.5$ years) conducted the eight flower arrangement tasks, range of motion for joints and muscle activation of upper limb were measured by a 3D motion analyzer and electromyography, respectively. Based on the results of the range of motion and muscle activation of upper limb, horticultural therapy programs using flower arrangement tasks (total 33 sessions) for improving upper limb function of the patients with stroke was conducted at a rehabilitation hospital, Seoul, South Korea and then the range of motion, grip strength, and upper limb function of the patients were tested. Among the eight flower arrangement tasks, cutting 1, winding, and bending 1 induced the highest value for the range of motion in joints of shoulder, elbow, and wrist, respectively (P < 0.001). In terms of muscle activation, eight flower arrangement tasks performed in this study showed various patterns of muscle activation and several muscles were simultaneously used for each task (P < 0.001). In addition, thickness and length of the materials used in a task had a prominent effect on the range of motion for joints and muscle activation of upper limb (P < 0.001). The stroke patients had positive effects for their range of motion of upper limb (shoulder, forearm, and elbow), grip strength, and overall upper limb function through the horticultural therapy program. Thus, this study suggested that flower arrangement tasks would be a potential horticultural activity for physical rehabilitation program. It would be interesting to apply a customized horticultural therapy program using flower arrangement tasks according to the symptoms of patient for physical rehabilitation.

• Proceedings of the KSMRM Conference
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• 2003.10a
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• pp.26-26
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• 2003

목적： 본 연구의 목적은 미각자극에 대한 인간 뇌의 활성화 영역을 측정하고 가시화하여 미각의 뇌 활성화 부위에 대한 기초자료를 마련하는데 있다. 대상 및 방법： 5명의 남자 대학생 (평균 24.8세)을 뇌기능 연구의 실험 대상자로 선정하였고, 대상자들은 미각에 이상이 없고 구강수술 경험이 없는 오른손잡이를 대상으로 3번에 걸쳐 EPI 혈액산 소농도의존(blood oxygen level dependent)법을 이용하여 미각자극에 의한 기능적 자기공명영상 실험을 수행하였다. 미각 자극을 위하여 5％의 saline을 사용하였으며 자체적으로 제작한 Stimulator를 사용하여 자극하였다. 자극은 3회의 휴식기간과 2회의 자극기간에 걸쳐 시행하였으며, 각 자극기간은 30초씩 5초 간격으로 이스 당 42개의 영상을 획득했다. Post-processing은 SPM99 (Statistical Parametric Mapping 99, The Wellcome Department of Cognitive Neurology, Oxford 1999)의 correlation법을 사용하여 threshold 0.4∼0.7의 범위에서 통계처리 하였으며, 활성화 영상은 EPI영상과 같은 부위의 T1 강조영상에 overlapping시켰다. 이렇게 얻어진 fMRI 영상으로 활성 영역의 위치를 분석하였다.

• Journal of the Korean Society for Precision Engineering
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• v.21 no.11
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• pp.140-148
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• 2004

Tight integration of product design and process planning in the early design stage would make bigger impact as wider spectrum of design and manufacturing alternatives can be pursued and evaluated. Thus the development of systematic computer-based supporting for this integration if desirable. For this integration and process planning in the early design stage, the systematic method to synthesize shape of part from functional requirements is crucial. This research presents the methods of functional decomposition from overall function of product and synthesizing shape of part based on functional relations extracted from functional decomposition using planetary gear transmission system as an example.

• Korean Journal of Clinical Laboratory Science
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• v.47 no.4
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• pp.267-272
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• 2015

'Tight junctions (TJ)' have recently been identified in the granular cell layer of the human epidermis, where they contribute to the normal adhesion between keratinocytes and to the physiologic barrier function of the epidermis. Among the TJ proteins in the epidermis, occludin is an important transmembrane protein, which is considered as a major component. The purpose of this study is to investigate whether regional variation exists in the expression of the tight junction protein occludin in normal human epidermis. Indirect immunofluorescence staining for occludin was performed with specimens taken from different areas of normal skin (4 from each of 7 different anatomical sites, including the scalp, face, posterior neck, upper arm, abdomen, lower back, and inner thigh). The degrees of the expression-intensity in each specimen were estimated with the reciprocals of positive end-point titer of occludin in an indirect immunofluorescence study. The highest degree expression-intensity of the TJ protein occludin among the different areas of normal epidermis was observed on the face and abdomen with a titer of 600 (p=0.001). The lowest intensity of expression of occludin was seen in the epidermis from the upper arm. Skin specimens from the scalp, neck, back, and leg demonstrated intermediate degrees of the expression in intensity. The expression of occludin in the skin samples obtained from different locations of the body showed a statistically significant variation. This suggests that there is a certain degree of regional variation in the expression-intensity of TJ protein 'occludin' in the human epidermis.

• The Korean Journal of Zoology
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• v.35 no.4
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• pp.414-427
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• 1992

Octopus variabilis의 흡반을 광학현미경과 주사전자현미경 그리고 투과전자현미경을 이용하여 그 미세구조를 관찰하였기에 이에 보고하는 바이다. 또한 내측상피 부위 돌기구 조물 속에서 관찰된 세포들은 핵을 둘러싼 세포들이 공포화 현상으로 인하여 해면처럼 보였다. 이 세포들은 감각과 수축에 관여하는 해면질성인 세포로 생각된다. 외측 상피조직에서는 2종의 분비성인 감각세포(A 및 B형세포)차 2종의 상피성인 감각세포(C 및 D형세포)가 관찰되었다. 분비성인 감각세포는 감각이외에 점액분비 기능을 소지하였으며, 상피성인 감각세포는 상피의 지지와 감각기능을 수행하는 것으로 생각되었다. 흠반을 구성하고 있는 근섬유는 중앙이 기린 도나스 형태로서 10-15개의 종선이 나타났다. 또한 부위에 따라서는 근섬유들은 서로 집결하여 원주형의 근육 기등을 형성하기도 했는데 이들은 신경섬유에 의하여 서로 연결 되고 통제되었다.

• Analytical Science and Technology
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• v.25 no.5
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• pp.333-338
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• 2012

IQ motif-containing GTPase-activating proteins (IQGAPs), which are well-known $Ca^{2+}$-independent calmodulin (CaM) binding proteins, are involved in various cellular functions such as cell proliferation, carcinogenesis and cell migration. The IQGAP3 similar to IQGAP1 has four repeated IQ motifs, which are crucial for CaM binding. It has been recently shown that all four IQ motifs of the IQGAP1 could bind to CaM, while not clear the binding of four IQ motifs of the IQGAP3. In this study, we examined the binding between CaM and each IQ motif of IQGAP3. As a result, we found that IQ2 and IQ3, but not IQ1 and IQ4, have a $Ca^{2+}$-independent CaM binding activity. We also found that IQ(3.5-4.4) on the IQGAP3 has $Ca^{2+}$-dependent CaM binding activity as similar with that of IQGAP1. This finding indicates that IQ motifs of the IQGAP3 plays a dynamic role via different interaction of IQ motifs with $Ca^{2+}$/CaM or apoCaM.

• Korean journal of food and cookery science
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• v.31 no.4
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• pp.510-514
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• 2015

Various parts of Kkujippong (Cudrania tricuspidata Bureau) tree (leaves, stems, roots, and fruit) were evaluated to determine their properties. The general components of Kkujippong tree were fat 1.3-5.9 g /100 g, protein 6.3-18.7 g /100 g, and ash 2.8-9.0 g /100 g. The fiber content of the stem was the highest amount at 69.2 g/100 g, followed by protein in the roots (49.9), leaves (45.5), and fruit (15.6). In addition, Kkujippong tree was found to contain high concentrations of several minerals (Ca, Fe, Mg, Na, P, Zn) in the leaves. The total polyphenol content was significantly higher in the leaves than in other areas at 571.3 mg% (p<0.05). Electron donating ability was also highest in the leaves at 83.55% (p<0.05).