• Title/Summary/Keyword: 근전이

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Changes of Serum soluble ICAM-1 levels in Patients with Lung Cancer (폐암 환자에서 혈청 soluble ICAM-1농도의 변화)

  • Yoo, Wan Hee;Lee, Yong Chul;Rhee, Yang Keun
    • Tuberculosis and Respiratory Diseases
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    • v.43 no.4
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    • pp.527-535
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    • 1996
  • Background : Cell adhesion molecules knave been Implicated In the various stages of tumor progression and metastasis. ICAM-1 plays a important roles in cell-cell interactions in inflammatory and immune response of several diseases. Recently, elevated levels of sICAM-1 in circulation was reported as association with liver metastasis in gastric, Colonic, gall bladder and pancreatic cancer, with reduced survival in malignant melanoma. This study was performed to measure the sICAM-1 in patients with lung cancer and to evaluate the relations between staging of lung cancer and level of sICAM-1. Methods : Serum sICAM-1 was measured in 36 patients with lung cancer according to the pathologic types and clinical staging before therapy and in 8 controls with ICAM-1 ELISA kit. Results : Serum sICAM-1 levels were elevated in patients with lung cancer except small cell type. Also progression and metastasis of lung cancer associated with elevation of sICAM-1 levels. Conclusion : These results suggest that higher levels of serum ICAM-1 reflect the progression and metastasis of lung cancer and it may be used as a marker with diagnostic and prognostic significance.

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Treatment of Squamous Cell Carcinoma in Extremity (사지에 발생한 편평세포 상피암의 치료)

  • Lee, Doo-Hyung;Shin, Kyoo-Ho;Lee, Soo-Hyun;Hahn, Soo-Bong
    • The Journal of the Korean bone and joint tumor society
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    • v.11 no.2
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    • pp.126-133
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    • 2005
  • Purpose: to know the treatment result of squamous cell carcinoma in extremity had poor prognosis with risk factor including burn scar and chronic osteomyelitis. Material and Methods: Between Octorber 1993 and September 2002, 20 patients with squamous cell carcinoma in extremity had no distant metastasis was got operation and followed over 36 months. Amputation was done when it was hard to get enough wide margin or neurovascular structure was involved instead of wide excision. Mean age of patients was 57.2 years old and male to female was 16 to 4. TMN staging and histologic grading were performed. Results: There were 6 metastasis (30%) in 20 cases for mean 48.3 months (36-84 months). 3 metastasis to local lymph node and 3 distant metastasis were happened at lung (in 3 cases) and thorasic vertebra (in 1 case). Survival was 18 cases at last look. 5-year survival rate was 50%. 3 local recurrence was developed at average 11 months (4-18 months). Complication was focal skin defect after wide excision and skin graft in 2 cases. The patients by wide excision got average 1.9 time operation and by amputation got average 1.3 time. Conclusion: Squamous cell carcinoma at extremity in Korea had high metastasis rate due to burn scar and chronic osteomyelitis, and it showed equal treatment result which treated by wide excision compared with amputation.

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Synchronous Double Primary Malignant Neoplasm Consisted of Myxofibrosarcoma of the Forearm and Adenocarcinoma of Rectum (전완부의 점액섬유육종과 직장의 선암이 동반된 동시성 다발성 원발성 종양)

  • Chung, Kee-Yun;Chun, Young-Soo;Han, Chung-Soo;Choi, Il-Hoen
    • The Journal of the Korean bone and joint tumor society
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    • v.14 no.2
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    • pp.146-151
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    • 2008
  • Multiple primary malignant neoplasm of the combination of the musculoskeletal system and the gastrointestinal system were very rare. A case of synchronous double primary malignant neoplasm consisted of myxofibrosarcoma of forearm and adenocarcinoma of rectum in a 52 year-old man was found. The patient had pain and swelling on forearm for 1 year. Histologically, the lesion on forearm showed myxofibrosarcoma. In systemic evaluation, the adenocarcinoma of rectum was found by the sigmoidoscopy, and metastasis on lung and intracardiac mass were found by the CT scan. We performed surgical excision and pre and postoperative chemotherapy after pathologic confirmation. He died of pulmonary thromboembolism after postoperative 2 months. We report this case of exceedingly rare combination of the musculoskeletal system and the gastrointestinal system.

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The Effect of Sports Elastic Compression Stockings on Lower Extremity Edema by High Intensity Exercise (스포츠용 탄력압박스타킹이 최대 운동 시 하지의 부종에 미치는 영향)

  • Jung, hye-won
    • Proceedings of the Korea Contents Association Conference
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    • 2013.05a
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    • pp.383-384
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    • 2013
  • 본 연구는 스포츠용 탄력 압박 스타킹(Essential compression calf sleeve, SKINS, Australia)을 착용하고 최대 운동을 하였을 때, 하지 부종에 어떠한 효과가 있는지를 알아보고자 한다. 실험 대상자는 젊은 성인 남녀 30명으로(남자 15명, 여자15명) 근 골격계 및 심혈관계에 특이 병력이나 사고에 의한 외상 등이 없었으며, 규칙적으로 운동을 하는 자는 제외하였다. 대상자들의 신체적 특성을 파악하기 위해서 자동 신장계(BSM330, Biospace, Korea)를 사용하였다. 부종정도를 알기위해서 줄자로 운동 전후의 장딴지 근(종아리)의 둘레와 체성분 분석기(InBody 720, Biospace, Korea)를 사용하여 하지의 부종 수치를 측정하였다. 최대의 운동은 호흡가스 분석기와 연결된 트레이드밀(CPEX-1, IRS, Japan)을 사용하여 변형된 BRUCE Protocol TR-3에 따라 호흡 교환율(R) 값이 1.15이상 되거나 all-out 될 때까지 하였다. 실험 대상자들은 동일 집단으로 전이효과를 방지하기 위하여 일주일의 간격을 두고 스포츠 탄력 압박 스타킹 착용 유무에 따른 동일한 실험을 두 번 하였다. 측정은 최대 운동 전후의 장딴지 근(종아리)의 둘레와 부종 수치를 하였다. 스포츠용 탄력 압박 스타킹 착용 유무와 운동 전후를 비교하기 위하여 MANOVA(다변량 분산분석)를 사용하였고 유의수준은 .05로 설정하였다. 탄력 압박 스타킹을 착용한 상태에서 최대 운동 전후의 부종 정도를 측정한 결과 스타킹을 착용하지 않았을 때 운동 전후의 둘레가 유의하게 증가하였고(p<0.05), 스타킹을 착용 하였을 때 운동 전후의 둘레가 유의하게 증가하지 않았다(p>0.05). 부종 수치(세포외액/전체체액)는 탄력 압박 스타킹을 착용하였을 때 오른쪽 다리는 유의하지 않게 감소하였고(p>0.05), 왼쪽 다리는 유의하게 감소하였다(p>0.05). 탄력 압박 스타킹을 착용하고 운동할 경우 하지의 부종 경감에 어느 정도 효과가 있다고 사료된다.

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Surgery for Cancer Arising at an Anastomotic Site after Radical Total Gastrctomy (위전절제술 후 문합부에 발생된 암에 대한 수술)

  • Yoon, Ho-Young;Lee, Sang-Hoon;Kim, Choong-Bai
    • Journal of Gastric Cancer
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    • v.7 no.3
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    • pp.174-179
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    • 2007
  • The survival of patients with gastric cancer is improved by early diagnosis and surgical treatment. However, there is no established treatment for locally recurrent cancer or cancer arising at an anastomotic site after total gastrectomy; further, most surgeons are reluctant to resect this type of cancer because of frequent systemic metastasis and there are few competent surgeons who have the skill to perform such an operation. We have experienced recurrent cancer at an anastomotic site after total gastrectomy: one patient had recurrent cancer and two patients had metachronous cancer. All these patients were operated on and the patients were discharged without any complications. All of them are alive at the time of this report. In some cases, good results could be expected for operating on recurrent cancer of an anastomotic site after previous total gastrectomy. So, we present here our experience along with a review of literatures.

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Kinetic Studies on Nucleophilic Substitution Reactions of Alkane Sulfonylchlorides with Anilines in MeOH-MeCN Mixtures (메탄올-아세토니트릴 혼합용매에서 염화알칸술포닐과 아닐린의 친핵 치환반응에 대한 속도론적 연구)

  • Ikchoon Lee;Han Keun Kang;Hai Whang Lee
    • Journal of the Korean Chemical Society
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    • v.29 no.5
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    • pp.478-481
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    • 1985
  • Nucleophilic substitution reactions between Alkanesulfonylchlorides and p-substituted anilines in methanol-acetonitrile mixture have been studied kinetically. Reactivities of substrates, substituent effects of nucleophile and solvent effects indicate that the studied reaction proceeds via $S_N2$. The kinetic results show that transition state of the reaction between i-PSC and anilines becomes looser as the composition of methanol increases.

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Krukenberg Tumor Presenting with Brain Metastasis - A Case Report - (뇌 전이를 동반한 크루켄베르크 종양 - 증 례 보 고 -)

  • Kwon, Taek-Hyun;Cho, Tai-Hyoung;Lim, Dong-Jun;Park, Jung-Yul;Park, Youn-Kwan;Chung, Yong-Gu;Chung, Hung-Seob;Suh, Jung-Keun
    • Journal of Korean Neurosurgical Society
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    • v.29 no.9
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    • pp.1267-1270
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    • 2000
  • Krukenberg tumor has been traditionally defined as gastrointestinal malignancy metastatic to the ovary, and is known to account for 1 to 3% of ovarian neoplasms. The nature and behavior of this particularly virulent tumor still remains unclear. We have experienced a case of Krukenberg tumor with brain metastasis. A clinical description of our case is presented with a review of the literature.

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Design of 77-GHz Automotive Radar Frontend Modules (77 GHz 대역 차량용 레이더의 프론트 엔드 모듈 설계)

  • Park, Sangwook;Kwon, Manseok;Kam, Dong Gun
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.25 no.4
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    • pp.487-490
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    • 2014
  • This paper describes a design of an automotive radar frontend module with taking care of the routing of 77-GHz signals on a printed circuit board including wire-bond and waveguide transitions.

Studies on Transformation of Domestic Kaolin (국산 Kaolin의 개질에 관한 연구(Halloysite에서 Kaolinite로의 전이))

  • 이종근;이병하;김성일
    • Journal of the Korean Ceramic Society
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    • v.14 no.2
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    • pp.82-87
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    • 1977
  • The material used in this experiment is Ha-Dong kaolin whichis composed of almost crystallographically pure meta-halloysite. It was grinded and passed through 250 mesh and 325 mesh. It was treated with oxalic acids and EDTA which are different in concentration. The samples in conical beaker were kept in laboratory incubator at $25^{\circ}C$ for a certain hours. The treated samples were stirred twice a day. The sample in the conditions as A-7 was kept in an autoclave under the pressure of 3 atmospheric. The samples suspended in each solution were kept for 1.5, 3 and 6 months. The transformation of crystals was detected by X-ray spectrometer, electron microscopy, and infrared spectrometer. The sample through 325 mesh compared with one through 250 mesh was transformed much more. It took for 6 months to transfer from halloysite to kaolinite in EDTA, and 3~4 months under 3 atms in autoclave at the same condition. In oxalic acids it took more than 6 months.

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Timing Specification in Abstract Timed Machine (추상 시간 기계의 시간 명세)

  • 노경주;박지연;이문근
    • Proceedings of the Korean Information Science Society Conference
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    • 2000.04a
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    • pp.576-578
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    • 2000
  • 본 논문은 ATM(Abstract Timed Machine)에서의 시간 명세 방법에 대해서 기술한다. ATM은 임무 위급 시스템과 같은 실시간시스템을 명세, 분석 및 검증 할 수 있는 LTS(Labeled Transition System) 정형 기법이다. 실시간 시스템이 요구하는 많은 속성 중 특히 시간 제약에 대해서는 사용자나 개발자 모두에게 명확하고 간결한 명세기법이 요구된다. ATM에서는 전이와 모드의 시간 제약을 간략하게 표현할 수 있는 방법을 제공한다. 또한 주기적 동작을 패턴인식하여 보여주는 주기 주제 모드를 통하여 주기와 관련된 동작과 시간 제약을 쉽게 파악할 수 있게 하며 주기적 동작을 선택적으로 간략화하는 방법을 제공한다. 본 논문은 ATM의 다양한 시간에 대한 요구사항에 대한 표현방법을 기술하고 예를 통해서 살펴본다.

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