• Journal of Oral Medicine and Pain
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• v.37 no.4
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• pp.227-231
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• 2012

Localized myositis ossificans is a disease with the main feature of formation of heterotropic bone and fibrous tissue involving muscle. It also called traumatic myositis ossificans. Myositis ossificans is likely to occur in the femoral region or brachium but, rarely in the head and neck including the masticatory muscles. It arises from traumatic episodes caused by prolonged mouth opening, surgical procedure, local anesthesia injection. The main clinical feature is the mouth open limitation. The diagnosis of myositis ossificans is usually based on the patient's history, clinical symptoms and on imaging finding. We present the case of patient with localized myositis ossificans of the temporal and lateral pterygoid muscles.

• The Korean Journal of Malacology
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• v.20 no.2
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• pp.111-120
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• 2004

We investigated the reproductive cycle of Corbicula japonica with its gonadal development by histological observations, and the seasonal changes in biochemical mass and foot muscle of the adductor muscle, visceral mass and foot muscle of the clam by biochemical analysis, from January to December, 2003. The reproductive cycle of this species can be classified into five successive stages: early active stage (February to April), late active stage (April to July), ripe stage (June to August), partially spawned stage (July to September) and spent/inactive stage (September to March). According to ANOVA test, there were significant differences (p < 0.05) in total protein, total lipid and glycogen contents among months for all of the visceral mass, adductor muscle and foot muscle. Total protein content was highest in adductor muscle, while lowest in visceral mass. There was no correlation in total protein content between visceral mass and adductor muscle (p = 0.208). However, strong positive correlation was found between adductor muscle and foot muscle (r = 0.769, p < 0.001). In visceral mass, total lipid content was the highest; it was 2 or 3-fold higher than in adductor muscle or foot muscle. The monthly change was also most dynamic in visceral mass. It decreased from January to March (early active stage), and reached maximum in April (late active stage). From May to August (ripe and partially spawned stage), it dradually decreased and then increased again until October (spent/inactive stage). Multiple comparisons showed that total lipid content in visceral mass between all of the adjacent two months was significaltly different (p < 0.05). There were strong negative correlations in total lipid content between visceral mass and adductor muscle (r = 0.687, p < 0.001), and between visceral mass and foot muscle (r = 0.473, p = 0.008). Changes of glycogen content were more or less similar to the changes of lipid contents in visceral mass, adductor muscle and foot muscle, except for April. In April, glycogen content in visceral mass was over four times higher than that in adductor muscle or foot muscle. There was a positive correlation in glycogen content between adductor muscle and foot muscle (r = 0.686, p < 0.001). Especially, total lipid content showed a negative correlation between the adductor muscle and visceral mass. Therefore, these results indicate that the nutrient content of the adductor muscle, visceral muscle and foot muscle changed in response to gonadal energy needs.

• Korean Journal of Ichthyology
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• v.26 no.3
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• pp.171-178
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• 2014

Myogenesis is the formation process of multinucleated myofiber with a contractile capacity from muscle satellite cell (MSCs) during life. This process is tightly controlled by several transcription factors such as Pax3 and Pax7 (paired box protein 3 and 7), MEF2C (myocyte enhancer factor 2) and MRFs (myogenic regulatory factors) etc. On the contrary, myostatin (MSTN) is a transforming growth factor-${\beta}$ superfamily, which functions as a negative regulator of skeletal muscle development and growth. Carnosic acid (CA) is a major phenolic component in rosemary (Rosmarinus officinalis) and have been reported various biological activities such as anticancer, antioxidant, antimicrobial and therapeutic agents for amnesia, dementia, alzheimer's disease. This study was confirmed to effects of CA on muscle cell line and muscle tissue alteration of zebrafish by intramuscular injection or feeding methods. $10{\mu}M$ CA showed a non-cytotoxic on myoblast and a complete inhibition effect against myostatin activity on luciferase assay. In intramuscular injection experiment, the total protein and triglyceride amount of $10{\mu}M/kg$ of CA injected group increased by 11% and decreased by 13% compared to these of the no injected group. In histology analysis of muscle tissues by hematoxylin/eosin staining, the number of muscle fiber of $10{\mu}M/kg$ of CA injected group decreased by 29% and fiber area increased 40% compared to these of no injected group. In feeding experiment, the total protein and triglyceride amount no significance difference compared to these of the normal feeding group. In histology analysis, the number of muscle fiber of 1% CA fed group decreased by 35% and fiber area increased 56% compared to these of normal fed group. We identified that CA have an effect on hypertrophy of muscle fiber in adult zebrafish and the results of this study are considered as the basic data that can reveal the mechanisms of muscle formation via gene and protein level analysis.

• Korean Journal of Poultry Science
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• v.6 no.1
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• pp.24-30
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• 1979

1. The effects of heat stress (38$^{\circ}C$), cold stress (4$^{\circ}C$) and extreme cold stress (-20$^{\circ}C$) before slaughter on the tenderness and postmortem glycolysis if the excised chicken breast muscle were studied Heat stress significantly (p 0.05) increased the toughness of breast muscle. Though statistically not significant, cold stress also adversely affected the tenderness. The heat-stressed birds showed higher zero hr glycogen higher zero hr pH and significantly (p 0.05) love. ultimate pH then the controls. The cold-stressed birds showed intermediate values in these parameters. Highly significant correlations. were observed between shear value and each of these three parameters. Glycolysis rate ana final moisture content were minor factors which affected the muscle tenderness to a limited extent. The slightly elevated lactate-dehydrogenase and creatine phosphokinase activities in serum and breast muscle of stressed birds failed to account for any variations in tenderness. 2. Chicken breast and thigh muscles were subjected to different environmental temperatures to determine if the phenomenon of cold shortening exists in chicken muscle. For both breast and thigh muscles, minimum shortening was observed in the 4-10$^{\circ}C$t range. Muscles held at 0$^{\circ}C$ showed a slightly higher extent of shortening than at 4$^{\circ}C$; where as muscles held at above 20$^{\circ}C$ showed a severe shortening effect. It was concluded that no apparent cold shortening was detected in chicken muscle except at 0$^{\circ}C$ and even at 0$^{\circ}C$ and even at 0$^{\circ}C$ the extent of shortening was of a small magnitude compared to bovine muscles. Since high temperature induces a much greater shortening, muscle temperature must be lowered to below 20$^{\circ}C$ as early as possible to prevent excessive muse]e shortening.

• Journal of Veterinary Clinics
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• v.29 no.1
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• pp.12-17
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• 2012

Many drugs are administered intramuscularly to immobilize and anesthetize dogs. There are many established intramuscular (IM) anesthetic combinations for dogs; however, little information is available on the effects of a xylazinediazepam-ketamine (XDK) combination. The purpose of this study was to investigate the anesthetic effects of the XDK combination in dogs. Twelve adult mixed bred dogs were used. All dogs were anesthetized with an IM injection of diazepam (0.5 mg/kg) and xylazine (1.1 mg/kg) with low-dose ketamine (5 mg/kg; group 1) or high-dose ketamine (10 mg/kg; group 2) in one syringe. After administration of the test dose, the animals were positioned in a right lateral recumbency, and analgesia and cardiopulmonary data were collected and recorded. The duration of anesthesia in group 2 was significantly longer than that of group 1 (mean [sd] 68.0 [7.6] v 51.3 [2.7] minutes). Blood pressure increased significantly after XDK administration in both groups, and $S_aO_2$ levels decreased significantly from baseline at 10, 20, and 30 minutes in both groups. XDK administration produced satisfactory sedation and analgesia in all dogs. In conclusion, intramuscular administration of xylazine-diazepam-ketamine combination at a doses of 1.1 mg/kg xylazine, 0.5 mg/kg diazepam, and 5 or 10 mg/kg ketamine appeared to be effective short duration anesthetic protocols in dogs.

• 종축개량
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• v.20 no.1
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• pp.93-102
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• 1998

3원교잡종의 지육지방축척과 육질에 대한 종료종모돈(두록종:D, 버크셔종:B, 매산돈:M)의 영향을 보기 위해, 랜드레이스종과 대요크셔종의 F1(LW) 종빈돈에 D, B 또는 M종의 3품종의 종모돈을 교배시켜 얻은 3원교 잡종(LWD, LWB, LWM)에 대해서 지육의 지방 축적량, 로스육의 물리적 특성과 화학적 조성 또는 근육섬유의 특성, 근육과 피하지방의 지방산 조성을 비교 검토했다. 시험돈은 3원교잡종 각각에 대해서 거세돈 수컷과 암컷을 각각 6두씩, 합계 36두를 공시했다. 단사(單飼), 무제한 급여 하에서 체중이 30kg에서 105kg가 될 때까지 사육했다. 도살한 돼지의 지육우반환(枝肉右半丸)의 제5-6, 8-9, 11-12, 13-14 흉추(胸椎) 간, 제16흉추-제1요추(腰推) 또는 최후요추-제1선추(仙推)간의 횡단면지방의 면적비율은 어떠한 부분에도 LMW이 LWD, LWB보다 통계적으로 유의가 많았다. 로스육의 물리적 특성치인 Tenderness는 $LWM961.3Kgw/cm^2)$ of $LWD(84.13KgW/cm^2)$와 $LWD(87.22KgW/cm^2)$보다 유의적으로 부드럽고, Pliability는 역으로 LWM이 LWD, LWB보다 유의 있게 낮았다. 또 로스육의 근육내 지방함량은 $LWM(3.23\%)$이 $LWD(2.32\%)$과 $LWB(2.35\%)$보다 유의성 있게 많았고, 가열 손실율(加熱損失率)은 LWM이 LWD, LWB보다 유의성 있게 높았다. 근섬유경(筋纖維經)은 LWD가 LWB, LWM보다 큰 경향으로 인정되어 지고, 근속(筋束)의 횡단면적은 LWD가 LWB 또는 LWM보다 유의 있게 조밀했다. LWM은 근육 내 지방산인 오레인산이 LWD, LWB보다 훨씬 높았고, 불포화 지방산의 비율이 높았다. 이상의 결과 종료종모돈이 3원교잡종의 육질에 영향을 미친다는 것이 명확하게 되었다.

• Proceedings of the Korean Society of Fisheries Technology Conference
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• 2002.10a
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• pp.118-119
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• 2002

근육이 수축하면 근원섬유의 sarcomere (근절)의 길이가 경직의 진행과 함께 짧아지는 것을 볼 수 있다. 즉, thick filament (myosin filament)와 thin filament (actin filament) 사이에서로 미끌어져 들어가는 현상이 일어나게 되는 것이다. 골격근은 보통 때는 이완상태에 있으나 필요할 때 신경자극에 의해서 수축을 하게 된다. 이러한 수축↔이완의 전환은 세포내의 $Ca^{2+}$ 농도의 조절을 통해서 제어되며, 이완시의 세포질 내의 $Ca^{2+}$ 농도는 정도의 낮은 상태로 유지된다. (중략)

• Proceedings of the Korean Society for Food Science of Animal Resources Conference
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• 2003.06a
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• pp.75-93
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• 2003

• Parasites, Hosts and Diseases
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• v.33 no.2
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• pp.131-134
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• 1995

When tachyzoites (RH strain) of Toxoplasmo gondii are injected intramuscularly, experimental mice survive up to 7 days, 1-2 days longer than those infected intraperitoneally. We observed sequential histopathological changes in inguinal Iymph nodes after intramuscular injection of tachyzoites to thighs of specific pathogen free (SPF) mice. Initial findings on 1 or 3 days after the injection were reactive germinal centers, distended sinuses and epithelioid cell clusters in cortical and paracortical regions. Later on 5 days after the injection, however, effacement of nodal structure with depletion of cells and focal necrosis were observed . Necrotizing Iymphadenitis in the experimental murine toxoplasmosis suggests the causal relation between T. gondii infection and the human disease.

• Journal of Veterinary Clinics
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• v.32 no.5
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• pp.404-409
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• 2015

The objective of this study was to compare the biocompatibility for local irritation and bioavailability of $Gentacol^{TM}$ and $Collatamp^{TM}$, after single intramuscular loading in rats. Sixty-six male Sprague-Dawley rats were divided into 4 groups; (1) any test materials were not applied into the quadriceps muscles (control group, N = 6), (2) Gentamicin was injected into the quadriceps muscles (Gentamicin group, N = 6), (3) Collatamp was applied into the quadriceps muscles (Collatamp group, N = 27), and (4) Gentacol was applied into the quadriceps muscles (Gentacol group, N = 27). The concentration of gentamicin in muscles was gradually decreased with time after loaded in the both $Gentacol^{TM}$ and $Collatamp^{TM}$ loaded regions. No detectable gentamicin was observed in the plasma of $Gentacol^{TM}$ and $Collatamp^{TM}$ loaded rats. Histologically, moderate to severe inflammatory cell infiltrations including PMN, lymphoid cells and macrophages were observed with slight to moderate edematous changes of muscle fibers after intramuscular injection of gentamicin. However, these histopathological changes of gentamicin injection induced local irritations were dramatically decreases after intramuscular loading of $Collatamp^{TM}$ and $Gentacol^{TM}$. These results suggest $Gentacol^{TM}$ may show favorable local bioavailability and induce only slight local irritations as comparable as $Collatamp^{TM}$ without systemic exposures in the condition of this experiment.