• Journal of the Korea Convergence Society
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• v.12 no.12
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• pp.411-418
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• 2021

The purpose of this study was to find out the effects of isomatric and isotonic exercise on the muscle function and cytokine which will prevent recurrence of breast cancer patients. A subjects were thirteen breast cancer patients and they were randomly assigned either isometric exercise group(n=10), isotonic exercises group(n=10) or a daily base care control group(n=10). Resistance exercise group did a exercise program with 60~70%RM for 60min, 3days per week during 8week. There were significantly difference between groups which were showing a increasing flexion, abduction, external rotation, IL-6 and IL-10 in isotonic exercise.

• Journal of the Korea Convergence Society
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• v.7 no.3
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• pp.185-193
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• 2016

The purpose of this study was to analyze the effects of combined exercise on body composition, funtional fitness and muscle protein synthesis related hormone in sarcopenic obesity elderly women. The subjects for the study were 20 obesity elderly women over 65 years old. They were divided into two groups, the sarcopenic obesity group(n=10) and non-sarcopenic obesity group(n=10). The variables of body composition and cardiovascular fitness were measured in all the subjects before and after 12-week combined exercise. The findings of this study were as follows; In the sarcopenic obesity elderly women (SG), % body fat significantly decreased in the SG group, FFM and ASM significantly increased. In the chair stand test and arm curl test, SG group significantly increased. SG group significantly changed in chair sit-and-reach test, back scratch test, 2-minute step test. In the muscle protein synthesis related hormone(growth hormone and IGF-1), SG group significantly increased.

• Korean Journal of Plant Tissue Culture
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• v.22 no.2
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• pp.71-76
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• 1995

The effects of light on the activities of several antioxidative enzymes, catalase (CAT), superoxide dismutase(SOD), ascorbate oxidase(AO), and peroxidase(POD) were examined in the hairy root cultures of Phytolacca esculenta van Houtte induced by Agrobacterium tumefaciens $A_4$T. Activities of CAT, SOD, and AO were significantly decreased with incresing light intensity (500-2,000 lx). The activity of AO under high light condition (2,000 lx)was decreased by 92% compared to the dark condition. The activities of glutathoine peroxidase (GPO), ascorbate peroxidase (APO) and general POD were increased under lower light intensify below 500 lx. The activity of GPO under 2,000 lx was decreased by 85% compared to the dark condition. The activities of antioxidative enzymes were more decreased in blue light (400-500nm). The activities of antioxidative enzymes in blue light intensity were increased in lower light intensity below 30 lx, but decreased 21-70% under 200 lx. The activity of AO was decreased by 70% under 200 lx with increasing blue light intensity. Our results suggest that the activities of antioxidative enzymes in hairy roots might be inhibited by endogenous oxidants generated under the high blue light conditions.

• Journal of Oral Medicine and Pain
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• v.24 no.1
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• pp.49-58
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• 1999

저자는 하악의 위치변화가 저작근에 미치는 영향을 근전도학적으로 평가하고자, 측두하악장애의 징후와 증상이 없는 정상성인 28명을 대상으로 중심위 교합장치(centric relation splint), 중심교합위 교합장치(centric occlusion splint), 전방 재위치 교합장치(anterior repositioning splint)를 장착시킨 상태에서 하악의 중심의, 중심교합위, 전방위률 유도한 후 최대 이악물기 상태의 좌우측 교근 및 전측두근의 근전도를 채득, 분석, 평가한 결과 다음과 같은 결론을 얻었다. 1. 전측두근에서 하악의 위치변화에 따른 최대 근활성도의 차이가 나타났으나(p<0.05), 교근에서는 나타나지 않았다. 2. 전측두근의 경우 중심교합위에서 최대 이악물기 상태의 최대 근활성도는 교합 장치물을 장착하지 않은 경우 및 중심위에서와 비교하여 감소하였다(p<0.05). 3. 전측두근의 경우 전방위에서 최대 이악물기 상태의 최대 근활성도는 교합 장치물을 장착하지 않은 경우 및 중심위에서와 비교하여 감소하였다(p<0.001). 4. 교근과 전측두근의 좌우 비대칭지수(asymmetry index)는 하악의 위치변화에 따른 차이가 나타나지 않았다.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 1994.04a
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• pp.122-131
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• 1994

본 연구에서는 배낭 어깨끈의 압박에 의한 통증과 신경 및 혈관압박을 감소시키기 위해 배낭 어깨끈의 압박부위 개선방안을 제안하고 이 배낭이 두가지 국부적 discomfort를 감소시키는 효과를 실험을 통해 평가하였다. 어깨끈 변형을 통해 등세모근 윗쪽부위 및 대흉근 바깥쪽부위의 압박을 대흉근 안쪽부위, 등세모근 중간부위 및 견갑골부위로 이동시키고 어깨끈과 등세모근 윗쪽부위는 접촉하지 않도록 하는 방안이 제안되었다. 실험결과 압박에 의한 통증과 신경 및 혈관압박의 정도가 어깨끈의 압박부위가 개선된 배낭에서 기존배낭보다 상대적으로 적은 것으로 평가되었으며 총체적인 선호도도 어깨끈의 압박부위가 개선된 배낭이 더 높았다. 보조적으로 배낭 착용시의 생리학적 부하정도를 측정한 결과, 개선된 배낭이 생리학적 부하를 효과적으로 감소시키지는 못하는 것으로 나타났으나 주관적 안락도 평가에서는 오히려 우수하였다. 이상이 결과는 본 연구에서 제안한 압박부위 개선배낭이 배낭 착용시의 안락도 결정에 있어 상대적으로 중요도가 높은 국부적 discomfort측면에서 기존배낭보다 우수하여, 생리학적 부하 측면에서는 개서효과가 없음에도 불구하고 전체적 안락도의 향상에 성공한 것으로 분석된다.

• Journal of Yeungnam Medical Science
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• v.11 no.2
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• pp.363-374
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• 1994

The purpose of this study was to investigate the characteristics or the potassium channels existing in the rat urinary bladders. Smooth muscle strips of rat detrusor urinae were examined by isometric myography. Relaxation responses of detrusor muscle strips to the three potassium channel openers pinacidil, a cyanoguanidine derivative, BRL 38227, a benzopyran derivative and RP 52891, a tertrahydrothiopyran derivative were examined. The potassium channel openers reduced the basal tone, and the rank order of potency was RP 52891>pincidil>BRL 38227. Procaine, an inhibitor of the voltage-sensitive potassium channel tended to increase the basal tone, but it did not affect the relaxant effects of the calcium-activated potassium channel opener did not antagonize the relaxant effects, but it reduced the Emax of RP 52891 and BRL 38227. Glibenclamide, an inhibitor of the ATP-sensitive potassium channel, antagonized the relaxant effects of pinacidil, RP 52891 and BRL 38227 reducing the Emax of RP 52891 and BRl 38227. Galanin which inhibits secretion of insulin through opening the ATP-sensitive potassium channels in pancreatic ${\beta}$-cells rather increased the basal tone of the isolated detrusor strips. These results suggest that the urinary bladder of the rat has mainly the ATP-sensitive, glibenclamide sensitive potassium channel, which is a different type from that in the pancreatic ${\beta}$-islet cells..

• KIPS Transactions on Computer and Communication Systems
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• v.12 no.3
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• pp.119-126
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• 2023

Sarcopenia is not well known enough to be classified as a disease in 2021 in Korea, but it is recognized as a social problem in developed countries that have entered an aging society. The diagnosis of sarcopenia follows the international standard guidelines presented by the European Working Group for Sarcopenia in Older People (EWGSOP) and the d Asian Working Group for Sarcopenia (AWGS). Recently, it is recommended to evaluate muscle function by using physical performance evaluation, walking speed measurement, and standing test in addition to absolute muscle mass as a diagnostic method. As a representative method for measuring muscle mass, the body composition analysis method using DEXA has been formally implemented in clinical practice. In addition, various studies for measuring muscle mass using abdominal images of MRI or CT are being actively conducted. In this paper, we develop an AI image segmentation model based on abdominal images of CT with a relatively short imaging time for the diagnosis of sarcopenia and describe the multicenter validation. We developed an artificial intelligence model using U-Net that can automatically segment muscle, subcutaneous fat, and visceral fat by selecting the L3 region from the CT image. Also, to evaluate the performance of the model, internal verification was performed by calculating the intersection over union (IOU) of the partitioned area, and the results of external verification using data from other hospitals are shown. Based on the verification results, we tried to review and supplement the problems and solutions.

• Proceedings of the Korea Information Processing Society Conference
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• 2019.05a
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• pp.291-292
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• 2019

본 논문은 의료영상을 기반으로 근감소증의 정량적 평가를 위한 특화된 분석 소프트웨어에 대하여 기술한다. 특히, 제안한 분석 소프트웨어는 복부 CT영상에서 근감소증 영상분석에 중요한 인자인 근육, 피하지방 그리고 내장지방의 영역을 반자동 방식으로 세그멘테이션하여 정량화 할 수 있다. 또한 각각의 영역별 레이블링 영상을 다양한 포맷으로 생성할 수 있다. 분석 소프트웨어는 근감소증의 진단 및 정량적 평가를 정의하는 출발점이 될 것으로 기대하고 있으며, 다양한 질환에 대해 분석에 적용이 가능하다.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1996.04a
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• pp.82-82
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• 1996

후두전적출술은 상부 소화관의 연속성을 변형시킴으로써, 식도운동의 장애를 가져올 수 있으며, 술 후에 연하곤란을 호소하는 경우는 10% 가량 된다. 본 연구의 목적은 식도내압검사를 통하여, 후두전적출술이 상부식도괄약근의 휴지기와 최대 압력에 어떠한 변화를 주는가 및 술 후 인두와 상부식도괄약근의 조화성 여부와, 만일 상부식도괄약근의 기능에 변화가 생긴다면, 그 영향이 식도체부 및 하부식도괄약근의 운동성에 어떠한 영향을 주는지를 알아보기 위함이다. 식도내압검사는 8개의 내관을 가진 폴리에틸렌 도관으로, 후두전적출술을 받은 환자군 14명과 정상인 12명을 대상으로, stational pull-through 방법으로 시행하였다. 환자군에서 상부 식도괄약근은, 휴지기 압력, 최대 수축압력, 이완정도, 괄략운동의 조화성 및 괄약근의 길이 등이, 정상 대조군 보다 의미있게 감소되었다. 환자군에 있어서 식도체부의 운동성은 주로 근위부 식도체부에서, 수축력, 수축기간 및 연동파의 전파시간이 대조군에 비하여 의미있게 감소되었고, 연동운동시 동시 수축도 3례에서 관찰되었다. 하부 식도괄약근의 기능은 환자군과 대조군이 의미있는 차이를 보이지 않았다.

• Journal of the Korean Applied Science and Technology
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• v.37 no.6
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• pp.1465-1474
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• 2020

The purpose of this study is the effects of 12 weeks complex training using swiss ball and elastic band on senior fitness and sarcopenia index in elderly women. The subject of this study was classified into exercise group (n=13) and control group (n=14). EG were carrier exercise program with swiss-ball and elastic band by 3 times a week, 3sets, RPE 11-13, and 60 minute. Test variables of among this study, senior fitness which is muscle strength, endurance, flexibility and dynamic balance and age-related sarcopenia index were muscle strength, muscle mass and short physical performance battery (SPPB). The results of this study were not significantly improvement at muscle strength, cardiopulmonary and flexibility but dynamic balance was significantly difference. And SPPB were significantly difference. In conclusion, the complex whole body training had positive effects on dynamic balance and SPPB of the elderly women.