• Title/Summary/Keyword: 극동

Search Result 426, Processing Time 0.025 seconds

Analysis of Efficiency of Recombinant pOPINEneo-3C-GFP Vector with p53 Tumor Suppression Gene Inserted (p53 암억제 유전자가 삽입된 재조합 pOPINEneo-3C-GFP 벡터의 효율 분석)

  • Sa, Young-Hee;Choi, Chang-Shik;Lee, Ki Hwan;Hong, Seong-Karp
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
    • /
    • 2019.05a
    • /
    • pp.533-536
    • /
    • 2019
  • Recombinant baculoviruses are widely used to express heterologous genes in cultured insect cells. Recombinant baculoviruses can serve as gene-transfer vectors for expression of recombinant proteins in a wide range of mammalian cell types. Baculovirus system has significant benefits in view of safety, large-scale, and high level of gene expression. In this study, baculoviral vectors which were reconstructed from pOPINEneo-3C-GFP vector, were recombined with cytomegalovirus (CMV) promoter, green fluorescent protein (GFP), and p53 with NcoI and XhoI. These recombinant vectors were infected with various cells and cell lines. The baculovirus vector thus developed was analyzed by comparing the metastasis and expression of the recombinant genes with conventional vectors. These results suggest that the baculovirus vector has higher efficiency in metastasis and expression than the control vector. This work was supported by a grant from Mid-Career Researcher Program(NRF-2016R1A2B4016552) through the National Research Foundation of Korea(NRF) funded by the Ministry of Science, ICT & Future Planning(MSIP).

  • PDF

The Development of VR based Application for Realistic Disaster Prevention Training (현실감 있는 재난재해 예방 교육을 위한 VR 기반 앱 개발)

  • Kim, Taehoon;Youn, Junhee
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.19 no.12
    • /
    • pp.287-293
    • /
    • 2018
  • The Korean peninsula has been known as an area that is free of volcanic disasters. However, recent observations and research results of volcanoes in Far East Asia, including Baedu Mountain and Japanese volcanoes, show that the Korean peninsula is no longer a safe area from volcanic disasters. Since 2012, the Korean government has been developing an IT-based construction technology, VDRS (Volcanic Disaster Response System), for effective volcanic disaster response system. The main users of VDRS are public officers in central or local governments. However, most of them have little experience and knowledge about volcanic disasters. Therefore, it is essential to develop education contents and implement training on volcanic disaster response for effective response in a real disaster situation. In this paper, we deal with the development of a mobile application based on virtual reality (VR) for realistic volcanic disaster response training. The objectives of training are the delivery of knowledge and experience for volcanic disasters. First, VR contents were generated based on spatial information. A 3D model was constructed based on a Digital Elevation Model (DEM), and visualization models for meterological effects and various volcanic disaster diffusion effects were implemented for the VR contents. Second, the mobile application for the volcanic disaster response training was implemented. A 12-step story board is proposed for volcanic disaster experience. The application was developed with the Unity3D engine based on the proposed story board to deliver knowledge of various volcanic disasters (volcanic ash, pyroclastic flows, volcanic mudflow etc.). The results of this paper will be used for volcanic disaster response and prevention training and for more realistic training linked with augmented reality technology in the future.

Geology and Volcanism of Hyeongjeseom (Islet) Volcano, Jeju Island (제주도 형제섬 화산체의 지질과 화산활동)

  • Park, Jun Beom;Koh, Gi Won;Jeon, Yongmun;Park, Won Bae;Moon, Soo Hyoung;Moon, Deok Cheol
    • Economic and Environmental Geology
    • /
    • v.54 no.2
    • /
    • pp.187-197
    • /
    • 2021
  • The Hyeongjeseom (Islet) is an erosional remnant of volcano which is located about 2 km northeast of sea shore of the Songaksan tuff ring, and is composed of volcaniclastic deposit, agglomerate and scoria deposit, ponded lava, aa lava flows, reworked deposit and beach deposit in ascending order from the base. The volcano is formed by volcaniclastic deposits and lava flows that recorded a transition from initial phreatomagmatic to magmatic explosions followed by lava effusion. It is interpreted that the outcropped volcaniclastic deposit may be a remaining portion of outer ring of a tuff cone. A bomb and a ponded lava yield geochemically basaltic trachyandesite compositions (SiO2 51.3 wt%, Na2O+K2O 6.0 wt%) and belong to olivine basalt with scarce (<5 %) phenocrysts of olivine, petrographically. By incremental heating Ar-Ar dating method, the plateau age of lava flow in the Heongjesom is 9.2±3.6(2σ) ka, implying that the volcanism of Heongjeseom may have occurred earlier than the Songaksan tuff ring which erupted ca. 3.7 ka. It still remains a task to find a volcano which matches with a historical record of volcanic activity that occurred a thousand years ago.

The Relationship between Apartment Price Index and Naver Trend Index (아파트가격지수와 네이버 트렌드지수 간의 연관성)

  • Yoo, Han-Soo
    • Land and Housing Review
    • /
    • v.13 no.4
    • /
    • pp.45-53
    • /
    • 2022
  • This paper investigates empirically the lead-lag relation between the 'apartment price index' and 'Internet search volume'. This study uses Naver Trend Index as a proxy for Internet search volume. An increase in Internet search volume on the apartment price index indicates an increase in people's attention to an apartment. Different from previous studies exploring the relation between 'the released price index of the apartment' and 'Naver Trend Index', this study investigates the relation of the Naver Trend Index with 'the fundamental price component of an apartment' and 'the transitory price component of an apartment', respectively. The results of the Granger causality test reveal that there are bidirectional Granger causalities between the 'released price' and Naver Trend Index. In addition, the 'fundamental price component of an apartment' and Naver Trend Index have a feedback relation, while 'the transitory price component of an apartment' Granger causes the Naver Trend Index uni-directionally. The impulse response function analysis indicates that the shock of apartment prices increases Naver Trend Index in the first month. Overall, The close relationship between apartment prices and Naver Trend Index suggests that increases in the movement of apartment prices are positively associated with public attention on the apartment market.

Trends of Life-Space Mobility in Community-dwelling Elderly (지역사회 거주 노인 대상의 생활공간 이동성(Life-space mobility) 연구 동향)

  • Jeong, Eun-Hwa
    • Therapeutic Science for Rehabilitation
    • /
    • v.10 no.1
    • /
    • pp.19-35
    • /
    • 2021
  • Objective : This study aimed to systematically examine studies on the life-space mobility in community-dwelling elderly and analyze and summarize the research trends. Methods : The Embase and PubMed databases were searched for articles on the life-space mobility of community-dwelling elderly published between January 2010 and January 2020. Based on the selection and exclusion criteria of the 335 articles, a total of 27 articles were finally selected and analyzed. Results : As a results, 11 (40.7%) cohort studies had evidence level II. This study showed that the participants in the studies were healthy elderly (81.5%), and the University of Alabama Life-Space Assessment (UAB-LSA) used the most participants (88.9%). Of the foci of the 27 finally selected studies, 8 (29.6%) were physical, 8 (29.6%) were psychosocial, 6 (22.2%) were cognitive, and 2 (7.4%) were social, and 3 (11.1%) were others. The life-space mobility of the elderly needs to be analyzed from a multidimensional point of view, and not based on a single factor such as the physical, cognitive, psychosocial, or social. Conclusion : The results of this study are expected to verify causality through the study of life-space mobility for the elderly staying in various communities and provide future directions for the study on the mobility of the elderly's and the development of community-based intervention programs.

Recognition of Toilet Terms and Pictograms by Elders Living in Seoul and Incheon (경인지역 노인의 화장실 용어와 그림문자 인식)

  • Lee, kyung Hee;Kim, Jung Hee;Sohn, Young Ae
    • 한국노년학
    • /
    • v.28 no.4
    • /
    • pp.1113-1128
    • /
    • 2008
  • Purpose: The aim of the present study was to investigate toilet terms and pictograms recognized by elders living in Seoul and Incheon. Method: Data were collected from 308 elders by individual interviews using questionnaires. Result: As for the name of places for elimination, those elders responded Hwajangsil 88.3%, followed by Byeonso 49.3% and Dwitgan 44.4%. Most elders preferred Hwajangsil as the term indicating the place for elimination. The mean age of the group preferred Bunso was significantly higher than that of the group preferred Hwajangsil, whereas educational level was higher in the latter group. Of the 256 respondents, 55% preferred the pictogram of international toilet sign, while 34.8% preferred the pictogram of toilet stool. Those with no formal education tended to prefer the pictogram of toilet stool. Conclusion: The term Hwajangsil is suggested for indicating toilet for elders in general. Other terms familiar with residents need to be investigated in the facilities for elders and those terms should be used in combination with Hwajangsil. English toilet signs alone are not recommended for elders. Simple pictograms of toilet stool is suggested for elders with low educational level. Toilet signs for elders need to include both terms and pictograms.

Design and Implementation of Anomaly Traffic Control framework based on Linux Netfilter System and CBQ Routing Mechanisms (리눅스 Netfilter시스템과 CBQ 라우팅 기능을 이용한 비정상 트래픽 제어 프레임워크 설계 및 구현)

  • 조은경;고광선;이태근;강용혁;엄영익
    • Journal of the Korea Institute of Information Security & Cryptology
    • /
    • v.13 no.6
    • /
    • pp.129-140
    • /
    • 2003
  • Recently viruses and various hacking tools that threat hosts on a network becomes more intelligent and cleverer, and so the various security mechanisms against them have ken developed during last decades. To detect these network attacks, many NIPSs(Network-based Intrusion Prevention Systems) that are more functional than traditional NIDSs are developed by several companies and organizations. But, many previous NIPSS are hewn to have some weakness in protecting important hosts from network attacks because of its incorrectness and post-management aspects. The aspect of incorrectness means that many NIPSs incorrectly discriminate between normal and attack network traffic in real time. The aspect of post-management means that they generally respond to attacks after the intrusions are already performed to a large extent. Therefore, to detect network attacks in realtime and to increase the capability of analyzing packets, faster and more active responding capabilities are required for NIPS frameworks. In this paper, we propose a framework for real-time intrusion prevention. This framework consists of packet filtering component that works on netfilter in Linux kernel and traffic control component that have a capability of step-by-step control over abnormal network traffic with the CBQ mechanism.

A Source-Level Discovery Methodology for Vulnerabilities of Linux Kernel Variables (리눅스 커널 변수 취약성에 대한 소스레벨 발견 방법론)

  • Ko Kwangsun;Kang Yong-hyeog;Eom Young Ik;Kim Jaekwang
    • Journal of the Korea Institute of Information Security & Cryptology
    • /
    • v.15 no.6
    • /
    • pp.13-25
    • /
    • 2005
  • In these days, there are various uses of Linux such as small embedded systems, routers, and huge servers, because Linux gives several advantages to system developers by allowing to use the open source code of the Linux kernel. On the other hand, the open source nature of the Linux kernel gives a bad influence on system security. If someone wants to exploit Linux-based systems, the attacker can easily do it by finding vulnerabilities of their Linux kernel sources. There are many kinds of existing methods for lading source-level vulnerabilities of softwares, but they are not suitable for finding source-level vulnerabilities of the Linux kernel which has an enormous amount of source code. In this paper, we propose the Onion mechanism as a methodology of finding source-level vulnerabilities of Linux kernel variables. The Onion mechanism is made up of two steps. The Int step is to select variables that may be vulnerable by using pattern matching mechanism and the second step is to inspect vulnerability of each selected variable by constructing and analyzing the system call trees. We also evaluate our proposed methodology by applying it to two well-known source-level vulnerabilities.

Comparison of Quantitative Relationship between Real-Time PCR and Acid Fast Bacilli Staining for Diagnosis of Pulmonary Tuberculosis (폐결핵 진단을 위한 실시간중합효소연쇄반응과 AFB 염색진단검사의 정량적 연관성 비교)

  • Jung, Taewon;Kim, Sang-Ha;Kim, Sunghyun;Choi, Jae-Sun;Kim, Young-Kwon
    • Korean Journal of Clinical Laboratory Science
    • /
    • v.52 no.4
    • /
    • pp.335-341
    • /
    • 2020
  • This study investigates the association of the AFB stain with the cycle threshold (Ct) value of the Cobas TaqMan MTB test (CTM test, Roche Diagnostics, Basel, Switzerland), and it establishes the base data for semi-quantitative identification of M. tuberculosis by the Ct value. CTM test were simultaneously conducted on 8,389 specimens submitted to the Samsung Medical Center from January 2015 to December 2015, and the results were analyzed and compared retrospectively investigates the association of the AFB stain with the Ct value of the CTM test, and it establishes the base data for semi-quantitative identification of M. tuberculosis by the Ct value. The Ct values for 135 positive specimens of the CTM were inversely correlated with the AFB stain (rs=-0.545, P<0.01). When the Ct value of the CTM test and the time to positivity (TTP) of the mycobacteria cultures were verified based on the AFB stain, they were found to have a positive correlation (rs=0.136, P<0.01). The negative correlation between the CTM test and the AFB stain grade was demonstrated. The clinical significance was verified by applying these criteria to the clinical results. The semi-quantitative criteria of this study can be used to facilitate the rapid isolation of patients with active tuberculosis and infection control in the hospital.

The Effect of Field Practice on Career Confidence of University Students (현장실습경험이 대학생의 진로자신감에 미치는 영향에 관한 연구)

  • Ka, Hye Young;Kim, Bo Young
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
    • /
    • v.16 no.2
    • /
    • pp.143-152
    • /
    • 2021
  • Recently, universities are being requested to educate a wider range of technical and social skills in order to respond to the government's policy for promoting youth employment and the industrial demand arising from social changes. Accordingly, field practice at universities is being further strengthened. It is important to analyze whether the work experience and information that students gained through field practice can improve their confidence in their career path, and can serve as a motive for not only employment but also start-up after graduation. In this study, the motivational aspect which leads to action by improving students' confidence in their career path is investigated. In addition, the influence of field practice experience on employability and entrepreneurial intention is also analyzed by setting a self-directed career attitude as a variables. The results of this study are as follows. First, the field practice experience of college students has a significant effect on employability, but does not directly affect their entrepreneurial intention. Second, it is confirmed that the higher the self-directed career attitude of students with experience of field practice has a positive (+) effect on the employability. Third, the higher the self-directed career attitude has also a positive (+) effect on entrepreneurial intention. This study shows the influence of field practice on employability and entrepreneurial intention beyond the limit of the existing research that was divided into employment and start-up. Theoretical basis for analyzing whether universities can achieve practical results simultaneously in government policy for employment and start-up is also provided.