• Polymer(Korea)
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• v.31 no.4
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• pp.329-334
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• 2007

Osmotic pellet system, which is one of the oral drug delivery systems, has been developed to improve manufacturing process, reduce product cost and other problems of osmotic tablet systems. Osmotic pellet is consisted of water swellable seed layer, drug layer, and membrane layer. Among them, the membrane layer plays an important role in a control of the drug release. In this work, we examined the effect of ratio for Eudragit RL and RS on the drug release behavior. Osmotic pellet with nifedipine as a model drug was easily obtained in a good yield by fluidized bed coater. Osmotic pellet showed round morphology with a range of size $1300{\sim}1500\;{\mu}m$. In the experiment of nifedipine release, the release amount increased with the increase of the ratio of Eudragit. This is due to the fact that Eudragit RL contains more hydrophilic quaternary ammonium group than Eudragit RS. Additionally, the release amount was retarded with increasing the membrane thickness. There are no differences in the release amount measured at the different pH 1.2, 6.5, 6.8, and 7.2. In conclusion, it was found that the drug release from osmotic pellets depended on the composition ratio and coating thickness of membrane layer.

• Journal of Korean Society of Environmental Engineers
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• v.31 no.8
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• pp.663-672
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• 2009

In this studies, the adsorption test using Chlorella pyrenoidosa was conducted to examine the effect of Pb adsorption according to various immobilized methods such as Ca-alginate, K-carrageenan, and Polyacrylamide. From the results, the duration to need to reach adsorption equilibrium was delayed according to the immobilization. And, the higher adsorption capacity of immobilized Chlorella pyrenoidosa was represented in the higher concentration of Pb, the smaller amount of immobilizing agent, and the higher pH of solution. The maximum adsorption capacity of Pb was shown in the adsorption test using Chlorella pyrenoidosa immobilized with Ca-alginate even though it was sensitive pH. The adsorption results properly represented with Freundlich isotherm equations. And, pseudo second-order chemisorption kinetic rate equation was applicable to all the biosorption data over the entire time range. The FT-IR analysis showed that the mechanism involved in biosorption of Pb by Chlorella pyrenoidosa was mainly attributed to Pb binding of carbo-acid and amide group. Adsorbed Pb on immobilized Chlorella prenoidosa was easily desorbed in the higher concentration of desorbents(NTA, HCl, EDTA, $H_2SO_4,\;Na_2CO_3$). Among the several desorbents, NTA showed the maximum desoption capacities of Pb from Chlorella pyrenoidosa immobilized with Ca-alginate and K-carrageenan and EDTA was the most effective in Chlorella pyrenoidosa immobilized with polyacrylamide. The desoprtion efficiency in the optimum condition was 90.0, 83.0, and 80.0%, respectively.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.24 no.8B
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• pp.1444-1455
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• 1999

In the standard location strategy such as IS-41 and GSM, Home Location Register(HLR) and Visitor Location Register(VLR) databases are used to manage the location of mobile terminals. The primary goal that location management schemes investigate is to reduce the cost of database access and the traffic for signaling network. When mobile terminals move frequently, one of problems in the standard location management scheme is that HLR database is highly updated and the traffic in signaling network can be occurred significantly due to high message transfer rate between HRL and VLR. As a solution to these problems, this paper proposes the location management scheme using VLR Gateway(VG) to reduce the both traffics of HLR update and signaling network which are resulted from location registration requirements of mobile terminals whenever they cross their registration area boundary. VG is a kind of database that is placed between HLR and VLR. It integrates one or more registration area defined in a system into one group and plays a role on behalf of HLR in a integrated registration scope so that the call delivery and the movement of mobile terminals are possible without HLR access in the scope. In order to evaluate performance of IS-41 and proposed scheme, we simulate two schemes based on wide range of call to mobility ratio. Its experiment result shows that in the proposed scheme total database cost increased slightly whereas HLR and signaling traffic decreased remarkably.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.42 no.1
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• pp.17-27
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• 2005

In this paper, we introduce a Parallel Interference Canceller (PIC) based sorting method to improve performance in the MC-DS/CDMA environment. A conventional PIC estimates and subtracts out all of the MAI (Multiple Access Interference) for each user in parallel. The parallel process ensures the low delay for the detection of all users. Also this scheme requires more stages for having better performance. Since the performance of PIC is strongly related to the correct MAI estimation, we introduce the IC (Interference Cancellation) scheme to estimate the accurate weaker signal group than the desired signal using conventional PIC. The principle of the proposed receiver sorts in descending order by the strength of signal and subtracts the MAI of the strong interferers from the desired signal for the accurate estimate of the weaker signals. Following this, the proposed scheme cancels out the improved weaker interference from the desired signal, using the output of the pre-step. In this result, the proposed system obtains better BER performance than the conventional PIC because the accuracy of the strong signal is improved. However, a disadvantage exists in that the processing time has slightly longer delay than the PIC owing to the power sorting and the MAI estimation process. The system performance evaluates and compares other non-liner It according to the number of sub-carriers in the limited-bandwidth.

• Korean Journal of Ichthyology
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• v.22 no.1
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• pp.25-33
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• 2010

Effects of different salinity levels on spawning performance, embryonic development and early viability of a euryhaline medaka species, Oryzias dancena, were examined. O. dancena were able to spawn eggs in a wide range of salinity from 0 to 70$^{\circ}/_{\circ\circ}$, however, the spawning frequency was lowered in complete freshwater (0$^{\circ}/_{\circ\circ}$) and in highly salted water (70$^{\circ}/_{\circ\circ}$). Fertilization success was negatively affected when the environmental salinity was higher than the salt concentration found in normal seawater. Embryonic viability and hatching success were also inversely related with the salinity levels. Typical abnormality was observed in developing embryos incubated at high salinities (30, 45 and 60$^{\circ}/_{\circ\circ}$). In addition, the time to hatch was significantly delayed with increasing salinities: peak hatching occurred at 12~14 days post fertilization (dpf) in freshwater and at least at 17 to 18 dpf in 60$^{\circ}/_{\circ\circ}$. Mean survival rates of the hatched larvae up to 7 days post hatching (dph) were at least 97% in salinity levels ranging from 0 to 30$^{\circ}/_{\circ\circ}$. However, larvae reared in 45 and 60$^{\circ}/_{\circ\circ}$ experienced significant mortality, especially in the early phase, resulting in only 75% and 64% survival rates up to 7 dph, respectively.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.43 no.1 s.343
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• pp.111-120
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• 2006

In this paper, a node architecture of WDM metro network for connecting broadband access networks to converge wire/wireless networks. In consideration of the proposed node architecture and network requirements we proposed and evaluated medium access control protocols. We review WDM related technologies of sub-carrier multiplexing and optical components in order to resolve the bottleneck between optical backbone networks md access networks, and a access node architecture sharing common wavelength is introduced. Source-stripping (SS) MAC protocol Is evaluated under the proposed functional node architecture. DS+IS (Destination-Stripping and Source-Stripping) and DS+IS (Destination-Stripping and Intermediate-Stripping) MAC protocols are described to increase the slot-reuse factor which is low on SS MAC protocol. The key function of new MAC protocols regards the optical switch module of proposed node architecture and helps intermediate or source access nodes for dropping slots to destinations of different wavelength group. Thus, slot-reuse factor increases as the MAC protocols reduce the unnecessary ring-rotation of transferred slots. We use a numerical analysis to expect bandwidth efficiency and maximum throughput by slot-reuse factor Throughput network simulation, the verification of throughput, queuing delay, and transmission fairness are compared among MAC protocols.

• Journal of the korean academy of Pediatric Dentistry
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• v.40 no.4
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• pp.296-305
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• 2013

For the purpose of evaluating the prevalence of malocclusion and self-esteem in adolescents, 1,380 middle-school students in the Yangsan area were surveyed by oral examination and questionnaires and the obtained results were as follows: The distribution of 1st molar occlusion by Angle's classification was 69.0, 19.4, 10.6% for Class I, II and III respectively. In the horizontal relationship, the prevalence of normal overjet and crossbite was 86.9% and 5.6% respectively whereas larger and extremely larger overjet was found in 6.6% and 0.8%. In the vertical relationship of anterior teeth, normal, deep overbite and openbite was shown in 94.1%, 4.7%, and 1.2%. For the midline discrepancy, the distribution of groups with 0~1 mm, 2~4 mm and over 5 mm was 98.2%, 1.4%, and 0.4%. Crowding only in the maxilla was found in 9.6%, while that only in the mandible and in both arches was 14.1% and 24.1% respectively. Spacing only in the maxilla was seen in 3.0%, while that only in the mandible and in both arches was 2.4% and 1.7% respectively. Significant difference in self-esteem was revealed in female and malocclusion groups of crossbite and openbite(p < 0.05).

• Journal of radiological science and technology
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• v.37 no.2
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• pp.135-141
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• 2014

This study was evaluated the linearity and reproducibility according to dose, and reproducibility according to delay time by changing tube current amount (5 mAs, 10 mAs, 16 mAs, 20 mAs, 25 mAs, 32 mAs respectively, which are low energy radiations) using Glass Dosimeter (GD) and piranha semiconductor dosimeter which are used for measuring exposure dose. Measurements of radiation dose were performed using external detector of piranha 657 which is multi-function QA device (RTI Electronic, Sweden). Conditions of measurement were 80 kVp, SSD 100 cm and exposure region is $10cm{\times}10cm$. Glass dosimeter was exposed to radiation. Twenty-four glass dosimeters were divided into six groups (5 mAs, 10 mAs, 16 mAs, 20 mAs, 25 mAs, 32 mAs respectively), then measured. This study was resulted by measuring the linearity and reproducibility according to change of tube current in low energy field. In dose characteristic of GD, this study could be useful as previous study with regard to dose characteristic according to change of tube voltage in low energy field.

• Journal of Life Science
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• v.16 no.7 s.80
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• pp.1090-1096
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• 2006

The purpose of this study was to investigate the effects of p. Linteus and C. militaris supplement on lactate, phosphorous, ammonia, MDA(malondialdehyde), GPX(glutathione peroxidase) and TAS(total antioxidant status) following $VO_{2max}$, and 85% $VO_{2max}$ exercise. The 15 male college students were divided into three groups: 5 P. liteus supplied(PL), 5 C. militaris supplied(CM), and 5 placebos supplied(PB) and compared the differences between supplement before and after. Obtained results were as follows: In the exercise performance time, there were no differences in PL, CM and PB groups. Regular supplement of P. linteus or C. militaris partially reduces fatigue induction factors. Also, P. linteus or C. militaris supplement decreases MDA, increases GPX and TAS. Therefore, it can be concluded that P. linteus or C. militaris supplement not only have a pharmacological effect for clinical treatment, but also have a maintenance effects on the tissue oxidant-antioxidant system after exercise.

• The KIPS Transactions:PartC
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• v.12C no.3 s.99
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• pp.429-436
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• 2005

A mobile ad hoc network (MANET) is a collection of mobile nodes without any fixed infrastructure or my form of centralized administration such as access points and base stations. The ad hoc on-demand distance vector routing (AODV) protocol is an on-demand routing protocol for MANETs, which is one of the Internet-Drafts submitted to the Internet engineering task force (IETF) MANET working group. This paper proposes a new multipath routing protocol called maximally disjoint multipath AODV (MDAODV), which exploits maximally node- and link-disjoint paths and outperforms the conventional multipath protocol based on AODV as well as the basic AODV protocol. The key idea is to extend only route request (RREQ) message by adding source routing information and to make the destination node select two paths from multiple RREQs received for a predetermined time period. Compared to the conventional multipath routing protocol, the proposed MDAODV provides more reliable and robust routing paths and higher performance. It also makes the destination node determine the maximally node- and link-disjoint paths, reducing the overhead incurred at intermediate nodes. Our extensive simulation study shows that the proposed MDAODV outperforms the conventional multipath routing protocol based on AODV in terms of packet delivery ratio and average end-to-end delay, and reduces routing overhead.