• Applied Biological Chemistry
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• v.46 no.1
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• pp.60-65
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• 2003

MMP-1 inhibitory compounds were isolated from 120 Korean traditional edible plants. UP- 1 activity significantly increased linearly with increasing UVB dose in normal human foreskin fibroblast HS68 cell, showing maximum activity at approximately 35 $mJ/cm^2$, whereas in HaCaT cell, normal human keratinocyte, no increase was observed. Maximum secretion of MMP-1 after UVB treatment occurred around 36-48 k after treatment. MMP-1 inhibitory compound isolated from cold-water fraction of Cataegus pinnatifida Bunge showed the mort potent activity. The MMP-1 inhibitory compound was deduced as a peptide based on the fact that pronase digestion decreased the activity whereas periodate oxidation did not. The most potent UP- 1-inhibitory protein, CP-2Va-2, showing an activity of 88.5% against MMP-1, was isolated through sequential column chromatography on DEAE-Toyopearl 650C, Butyl-Toyopearl 650M, and Bio-Gel P-30. Molecular weight of CP-2Va-2 determined through high performance liquid chromatography and SDS PACE was 19 and 20 kDa. respectively, signifying a monomeric structure.

• Journal of Korean Society of Steel Construction
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• v.29 no.6
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• pp.479-486
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• 2017

Steel beams with corrugated web have been widely used in the steel structures. However, it is challenging to weld the section between the corrugated web and the flange straight, which increases the cost of production. In order to solve this issue, steel beam with intaglio and embossed web (It is called an IEB) was invented. A web with embossment is produced by cold pressing and welded to flange by automatic welding machine. The loading tests were conducted to investigate the load-carrying capacity of IEB, and its test result was compared with that of H-shaped beam having a same size of flange and web. The test results of IEB series showed about 40% higher load capacities than H-shaped series. As a result of comparing the IEB specimen with Eurocodes for steel beams with corrugated web, all of specimens tested in this study did not meet the design value. Therefore, it is difficult to apply existing formula to IEB and new design formula should be presented for field application.

• Journal of Korean Society of Environmental Engineers
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• v.33 no.8
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• pp.564-571
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• 2011

In order to establish fundamental data for stream restoration and environmental flow, we investigated fish fauna, community and physical habitat conditions in the Dal Stream of Han River Basin. Field monitoring including fish sampling was conducted from September 2008 to October 2009. A total number of fish caught in the 5 sites was 2,080 representing 9 families 35 species, and 19 species (54.3%) including Acheilognathus koreensis and Iksookimia koreensis were Korean endemic species during the study period. The most frequently found species in number was pale chub (Zacco platypus, 25.7%, n = 632) followed by Coreoleuciscus splendidus (18.0%, n = 375) and Z. koreanus (13.0%, n = 272). The lower reach of Dal Stream was more abundance of species, high diversity, evenness and richness, and lower dominance index than those of the upper reach. According to the dendrogram established at 0.63 level of similarity rate, sampling stations were divided into 2 groups. Most of upper streams in Korea consist of riffles and runs that are repeatedly followed by another one. However, stream channelization and leveling have caused reduction of habitat diversity. Therefore, it is necessary to make an effort on stream rehabilitation with evaluation of physical habitat condition by indicator species in order to maintain biodiversity and perform ecological restoration.

• Journal of the Korean association of regional geographers
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• v.9 no.4
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• pp.505-518
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• 2003

The purpose of this paper is to review Post-Fordist urban economic theories that have tackled the recent changes of urban economies in large cities in the world since 1980s, so that we can conceptualise the changes of urban economies in Korean cities. In the perspective of the Post-Fordist urban economic theories, the recent changes of urban economies in the world are deeply related to the transformation of capitalist world economic system from Fordism to Post-Fordism. To see these changes which can be called as the new urbanization process in the economic aspect, we will focus especially such theories as new industrial space (district) theory based on the flexible specialization paradigm, informational city theory based on the information and communication mode paradigm, and cluster and regional innovation theory based on the institution and network paradigm. Also we will consider the social polarization process and dual city phenomena that have been observed for the most part of big cities in the world.

• Journal of Applied Biological Chemistry
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• v.60 no.2
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• pp.149-153
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• 2017

Contamination and growth of Trichoderma, a green mold, on the oak log and wooden chip or sawdust media can severely inhibit the growth of oak mushroom. Chemicals including pesticides and antibiotics are generally not allowed for the control of green mold disease during mushroom cultivation. In this study, bacterial pathogens causing blotch disease on the oyster mushrooms were isolated and their peptide toxins were purified for the control of green mold disease. Strains of Pseudomonas tolaasii secret various peptide toxins, tolaasin and its structural analogues, having antifungal activities. These peptides have shown no effects on the growth of oak mushrooms. When the peptide toxins were applied to the green mold, Trichoderma harzianum H1, they inhibited the growth of green molds. Among the 20 strains of peptide-forming P. tolaasii, strong, moderate, and weak antifungal activities were measured from 8, 5, and 7 strains, respectively. During oak mushroom cultivation, bacterial culture supernatants containing the peptide toxins were sprayed on the aerial mycelia of green molds grown on the surface of sawdust media. The culture supernatants were able to suppress the fungal growth of green molds while no effect was observed on the mushroom growth and production. They changed the color of molds from white aerial mycelium into yellowish dried scab, representing the powerful anti-fungal and sterilization activities of peptide toxins.

• The Journal of Engineering Geology
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• v.8 no.2
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• pp.175-188
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• 1998

This paper describes the internal structures and K-Ar ages of fault gouges collected from the Dongnae fault zone. This fault zone is internally zoned and occurs in the multiple fault cores. A fault core consists of thin gouge and narrow cataclastic zones that are bounded by a much thicker damage zone. Intensity of deformation and alteration increases from damage zone through cataclastic zone to gouge zone. It is thought that cataclasis of brittle deformation was the dominant strain-accomodation mechanism in the early stage of deformation to form the gouge zone and that crushed materials in the regions of maximum localization of fault slip subsequently moved by cataclastic flow. Deformation mechanism drastically changed from brittle processes to fluid-assisted flow along the gouge zone as the high porosity and permeability of pulverzied materials during faulting facilitated the influx of the hydrothermal fluids. Subsequently, the fluids reacted with gouge materials to form clay minerals. Fracturing and alteration could have repeatedly taken place in the gouge zone by elevated fluid pressures generated from the reduction of pore volume due to the formation of clay minerals and precipitation of other materials. XRD analysis revealed that the most common clay minerals of the gouge zones are illite and smectite with minor zeolite and kaolinite. Most of illites are composed of 1Md polytype, indicating the products of hydrothermal alteration. The major activities of the Dongnae fault can be divided into two periods based upon K-Ar age data of the fault gouges : 51.4∼57.5Ma and 40.3∼43.6Ma. Judging from the enviromental condition of clay mineral formation, it is inferred that the hydrothermal alteration of older period occured at higher temperature than that of younger period.

• The Journal of the Korea Contents Association
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• v.18 no.4
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• pp.586-600
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• 2018

The purpose of this study attempted to collect basic data for development of an integrated self-management program for cancer survivors who completed cancer treatment. Self-management programs are divided into symptom management and physical activity management. Symptom management includes fatigue, sleep disturbance, pain, depression and anxiety. PubMed, CINAHL and EMBASE were used for searching guidelines. Based on the guideline quality evaluation, the final 8 guidelines were analyzed. The structured table was used to extract the screening subjects, timing, contents, subjects for comprehensive assessment and contents, and summarized contents related to the physical activity and exercise in non-pharmacological approach. As a result, after the completion of cancer treatment, all cancer survivors should be screened regularly using reliable and validated tools. In the case of fatigue, physical activity was recommended as the primary intervention, but it was recommended for other symptoms as adjuvant therapy. Therefore, Cancer survivors should be encouraged to be active in their physical activity, and maintain the moderate intensity physical activity as long as they have no complication related to the cancer treatment. Motivation strategies for physical activity need to be developed and applied.

• Journal of Korea Technology Innovation Society
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• v.10 no.3
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• pp.486-508
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• 2007

This study identifies key determinants of participation in UCC services. Incorporating insights from the flow theory, we examine the effects of psychological factors of social presence, self expression, arousal, and challenge as well as web-site characteristics variables of media easiness, contents usability, and immediateness. We have done a sample survey of internet users and collected 260 responses. Using Windows SPSS/PC 12.0 Package, we have performed statistical analyses including a correlation analysis, a factor analysis, and a multiple regression analysis. The result of the study is as follows. Psychological variables of perceived social presence, self expression, arousal, and challenge all show positive significant effect on participation in UCC service. Among web site characteristics, media easiness, which consists of a web structure that is easy-to-use, user friendliness, and personalized service, demonstrates a positive significant effect on participation in UCC services. Immediateness also has a positive significant effect. Some of the practical implications of the result are follows. We should improve user access to platforms of UCC service by opening up platforms. This will heighten perceived challenge which has the strongest influence on participation in UCC services. We need to focus on multimedia services and adjust to the cultural code of netizen who crave for visual expressions and on the spot on-line activities. Also suggested is that contributions made by participants need to be acknowledged through such provisions as profit sharing. Needs for individualized service, which is an aspect of media easiness, should also be addressed. Participants tend to value individuality while at the same time accepting broader trends. Information services need to be customized for individuals. In UCC centered internet businesses, netizen consumers are presumer. They are consumers and producers at the same time, and consumer needs should also be explored for the success of internet businesses.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.8
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• pp.222-227
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• 2020

Pb(Zr,Ti)O₃(denoted as PZT) in the perovskite phase is used as a dielectric, piezoelectric, and super appetizer material owing to its ferroelectric properties. A PZT film was formed by an RF magnetron sputtering process by preparing a target composed of Pb_1.3(Zr_0.52Ti_0.48)O₃. The PZT film was formed by dividing the material into a mono-layer PZT produced continuously with the same sputtering power and a bi-layer PZT produced with two-stage sputtering power. The bi-layer PZT consisted of a lower layer produced under low-power sputtering conditions and an upper layer produced under the same conditions as the mono-layer PZT. XRD revealed small amounts of pyrochlore phase in the mono-layer PZT, but only the perovskite phase was detected in the bi-layer PZT. SEM and AFM revealed the upper part of the bi-layer PZT to be more compact and smooth. Moreover, the bi-layered PZT showed superior symmetry polarization and a significantly reduced leakage current of less than 1×10-5 A/cm². This phenomenon observed in bi-layer PZT was attributed to the induction of growth into a pure perovskite phase by suppressing the formation of a pyrochlore phase in the upper PZT layer where the densely formed lower PZT layer was produced sequentially.

• Journal of KIISE:Software and Applications
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• v.33 no.4
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• pp.402-410
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• 2006

This paper presents a method for feature based block motion estimation that uses multi -resolution image sequences to obtain the panoramic images in the continuous ultrasound image sequences. In the conventional block motion estimation method, the centers of motion estimation blocks are set at the predetermined and equally spaced locations. This requires the large blocks to include at least one feature, which inevitably requires long estimation time. In this paper, we propose an adaptive method which locates the center of the motion estimation blocks at the feature points. This make it possible to reduce the block size while keeping the motion estimation accuracy The Harris-Stephen corner detector is used to get the feature points. The comer points tend to group together, which cause the error in the global motion estimation. In order to distribute the feature points as evenly as Possible, the image is firstly divided into regular subregions, and a strongest corner point is selected as a feature in each subregion. The ultrasound Images contain speckle patterns and noise. In order to reduce the noise artifact and reduce the computational time, the proposed method use the multi-resolution image sequences. The first algorithm estimates the motion in the smoothed low resolution image, and the estimated motion is prolongated to the next higher resolution image. By this way the size of search region can be reduced in the higher resolution image. Experiments were performed on three types of ultrasound image sequences. These were shown that the proposed method reduces both the computational time (from 77ms to 44ms) and the displaced frame difference (from 66.02 to 58.08).