• 대한치과보철학회지
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• 제58권4호
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• pp.349-355
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• 2020

외상, 구강암, 선천적 요인 등에 의한 구강 결손시 음식물의 섭취, 흡입성 폐렴 방지, 안모 지지를 위하여 치과용 obturator가 제작된다. 그러나 기존의 전통적인 인상 채득 방법을 이용한 obturator제작 시, 제작 과정에서 술자와 환자, 기공사 모두 번거로운 과정을 거쳐야 하며, 환자는 악안면 보철 치료가 가능한 치과 보철 전문의가 있는 병원을 찾아 방문해야 하는 어려움이 있다. 그러나, 3D printing을 포함한 CAD-CAM 기술을 이용하면 비교적 간단하게 hollow obturator를 제작할 수 있고, 보철 전문의가 없는 지역에서도, 지역 치과의사와 멀리 떨어져 있는 보철 전문의 간의 협진을 통해 수월한 치료가 가능할 수 있다. 본 연구에서는 한국의 상악 구개 결손 환자들의 치료를 위해, 일본에서 obturator를 디자인하고 한국에서 3D printing하여 성공적으로 obturator를 제작하였고, 더불어 원격 치료의 가능성을 확인하였기에 보고하는 바이다.

• 대한치과의사협회지
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• 제47권6호
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• pp.373-378
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• 2009

This article presents a modified palatal pedicled incision design in anterior segmental maxillary osteotomy. This method included the circumcrevicular incisions and two vertical relaxing incisions. Then, it is different from the Couper's method with vestibular horizontal incision and other anterior segmental osteotomy techniques. The main advantages of this method are an improved visibility of surgical field and favorable preservation of palatal pedicle. A patient who had been operated by anterior segmental maxillary and mandibular osteotomy without pre operative orthodontic treatment was analyzed for advantages and complications during the intraoperative and early post operative period. There are no specific major complications such as infection, gingival recession and dehiscence. And the patient had a pleasing esthetic facial appearance.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제28권1호
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• pp.68-72
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• 2006

Mucoepidermoid carcinoma is one of the most common malignant salivary gland neoplasm. It occurs over a wide age range, and is most common in the parotid gland and usually appears as an asymptomatic swelling. Pain or facial nerve palsy may develop. Minor salivary gland tumors also typically appear as asymptomatic swellings, which are sometimes fluctuant and have blue or red color that can be mistaken clinically for a mucocele. Histopathologically the mucoepidermoid carcinoma is composed of a mixture of mucous-producing cells and squamous (epidermoid) cells. Low-grade tumors show prominent cyst formation, minimal cellular atypia, and relatively high proportion of mucous cells. Mucoepidermoid carcinoma of the minor salivary glands are treated usually by assured surgical excision. For low-grade neoplasm, only a modest margin of surrounding normal tissue may need to be removed, but high-grade or large tumors warrant wider resection. Postoperative radiation therapy also may be used for more aggressive tumors. Mucoepidermoid carcinoma of the oral minor salivary glands generally have a good prognosis, because they are mostly low-to intermediate grade tumors. We present a case of mucoepidermoid carcinoma managed with surgical enucleation and postoperative irradiation and a good clinical result with review of literatures.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제23권3호
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• pp.205-211
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• 2001

Cleft palate is one of the most serious congenital anomalies in human that causes a sucking problem in newborn babies and morphologic deformity that usually leads to death in newborn mouse offspring due to an insufficient ability to suck milk. Therefore cleft palate had been researched with epidemiologic and molecular methods, and many etiologic factors were examined closely. Among of the research methods, biologic molecule researches have been more important method for cleft palate formation study. The $TGF-{\beta}$ had an important role in the cell migration, epithelial-mesenchymal transdifferentiation, extracellular matrix synthesis and deposition. But there was a little research which was study about correlation cleft palate induced by beta-aminonitroproprionitrile(BAPN) with $TGF-{\beta}$ expression. A purpose of this presented study was examed how $TGF-{\beta}$ expression in cleft palate mice. At gestation days 13, BAPN-monofumarate salts($(C_3H_6N_2)_2$ ${\cdot}$ $C_4H_4O_4$, Sigma Co.) was single oral administered to 4 pregnant rats according to 1g/kg body weight. And pregnant rats were sacrificed on day 20 post coitus(p.c.), The $TGF-{\beta}$ expression patterns of cleft formed fetus mice was followed that; 1.Osteoblast, mesenchymal cell and epithelial cell of cleft mice were low expression compare to control mice. 2.There was no $TGF-{\beta}$ difference expression pattern of osteocyte of cleft mice compare to control mice. 3. In western blot analysis, thickness of band of $TGF-{\beta}$ in cleft mice was thin and dilute compare to control mice.

• Journal of Oral Medicine and Pain
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• 제19권2호
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• pp.7-23
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• 1994

구강내 작열감 증후군은 객관적 징후없이 구강점막에 작열감을 나타내는 만성동통장애이다. 다양한 원인요소들이 제시되어 있지만, 이러한 요소들의 관련성에 대해서는 아직 분명하지 않은 실정이다. 그러므로, 이러한 구강내 기능이상의 근본적이고 효과적인 치료를 위해서는 다양한 임상적 관찰과 원인요소의 분석등이 계속 연구 조사되어져야 할 것이다. 저자는 구강내 작열감 증후군의 증상을 호소하는 112명의 환자의 임상적 특징에 대해 조사하고자, 환자군과 대조군에 대해 구강내 작열감 증후군에 관한 설문조사 및 구강검사와 혈액학적 검사를 시행하였으며, 점도계를 사용하여 구강내 작열감 증후군 환자의 자극이 전타액의 점도를 측정하였다. 또한, 환자의 심리적 요인을 파악하고자 간이정신진단검사를 실시한 결과 다음과 같은 결론을 얻었다. 1. 구강내 작열감 증후군은 주로 페경기 전후의 여성에서 많이 나타났으며, 호발부위는 혀, 치주 및 치조점막, 구개, 협점막의 순이었다. 2. 구강내 작열감 증후군 환자에게서 대조군 비해 구강건조감, 미각 및 수면장애, 빈혈, 소화기 장애, 두통과 기타 다른 신체불편감의 호소 등이 더 많이 나타났다. 3. 혈액학적 검사결과, 구강내 작열감 증후군 환자중의 26%와 12%에서 각각 혈중 엽산농도와 철분농도의 저하를 나타냇다. 4. 자극시 분비된 전타액의 점도는 40대와 50대이상의 연령군에서 구강내 작열감 증후군 환자가 정상인에 비해 높았다.(p<0.01). 5. 구강내 작열감 증후군 환자군의 간이정신진단검사의 각 증상차원 및 전체지표의 T점수의 평균치는 정상범위내에 있었으며, 신체화(SOD)와 우울 (DEP)차원의 평균치가 가장 높았다.

• 구강회복응용과학지
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• 제26권1호
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• pp.33-38
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• 2010

상악의 악성 종양에 대한 치료로서 상악골 절제술이 시행되며 필연적으로 이것은 환자 구개부에 결손부를 생성한다. 이로 인해 안모의 변형, 연하, 저작, 발음 등 다양한 문제가 발생할 수 있다. 상악골 절제술 후 이런 문제들을 극복하기 위해 외과적 재건 또는 보철적 치료가 치료 방법으로 선택될 수 있으나 대부분의 상악골 절제술 환자에서 구강악안면 재건의 방법으로 구개폐쇄장치가 더 선호된다. 본 증례는 Aramany 분류 II급에 해당하는 상악골 부분 절제술을 시행한 환자에게 구개폐쇄장치의 유지와 안정을 얻고 모든 기존의 금관수복물을 유지할 수 있는 swing-lock attachment를 사용하여 수복한 임상과정 및 결과에 관하여 보고하고자 한다.

• Archives of Reconstructive Microsurgery
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• 제20권1호
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• pp.8-13
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• 2011

Purpose: A palatal defect following maxillectomy can cause multiple problems like the rhinolalia, leakage of foods into the nasal cavity, and hypernasality. Use of a prosthetic is the preferred method for obturating a palate defect, but for rehabilitating palatal function, prosthetics have many shortcomings. In a small defect, local flap is a useful method, however, the size of flap which can be elevated is limited. In 12 cases of palatomaxillary defect, we used various microvascular free flaps in reconstructing the palate and obtained good functional results. Method: Between 1990 and 2004, 12 patients underwent free flap operation after head and neck cancer ablation, and were reviewed retrospectively. Among the 12 free flaps, 6 were latissimus dorsi myocutaneous flaps, 3 rectus abdominis myocutaneous flaps, and 3 radial forearm flaps. Result: All microvascular flap surgery was successful. Mean follow up time was 8 months and after the follow up time all patients reported satisfactory speech and swallowing. Wound dehiscence was observed in 4 cases, ptosis was in 1 case and fistula was in 1 case, however, rhinolalia, leakage of food, or swallowing difficultly was not reported in the 12 cases. Conclusion: We used various microvascular flaps for palatomaxillary reconstruction. For 3-dimensional flap needs, we used the latissimus dorsi myocutaneous flap to obtain enough volume for filling the defect. Two-dimensional flaps were designed with latissimus dorsi myocutaneous flap, rectus abdominis flap and radial forearm flap. For cases with palatal defect only, we used the radial forearm flap. In palatomaxillary reconstruction, we can choose various free flap techniques according to the number of skin paddles and flap volume needed.

• 대한치과보철학회지
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• 제25권1호
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• pp.71-94
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• 1987

This study was carried out to investigate the sound distortion following the alternation of the palatal plate thickness. For this study, 2 healthy male subjects (24-year-old) were selected. Born in Seoul, they both spoke Seoul dialect. First, their sounds of /na(나)/, /da(다)/, /1a(라)/, /ja(자)/, /cha(차)/, /ta(타)/, without inserting plates were recorded, and then the sounds with palatal plates of different thickness were recorded, successively. The plate was fabricated in 3 types, each palatal thickness being 1.0mm, 2.5mm, dentoalveolar portion 2.5mm, other residual portion was 1.0mm, successively. Each type plates named B, C, D-type, in succession. Series of analysis were administered through Computer(16 bit) to analyze the sound distortions. These experiments were analyzed by the LPC (without weighting, pre-weighting, post-weighting) of the consonants, vowels portion, formant frequency of the vowels and word duration of the consonants. The findings led to the following conclusions: 1. There was no correlation of the distortion rate on the 2 informants. 2. Generally, vowels were not affected by the palatal plate thickness in the formant analysis, however, more distortion was detected in the LPC analysis, especially C, D-type plates. 3. Consonants distortion was more evident in the C, D-type plate. 4. The second formant was most disturbed and reduced in the all consonants with insertion of the palatal plate, especially C, D-type plate. 5. Word duration was shortened in the plate inserted(except /ja/, /cha/), especially C, D-type. 6. It was found that dentoalveolar, hard palatal sounds were severely distorted in plate inserted, and they were mainly affected by the dentoalveolar portion thickness. 7. There was correlation between palatal thickness and consonants quality.

• 대한소아치과학회지
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• 제30권2호
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• pp.286-290
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• 2003

섬유종은 구강 내에서 가장 흔히 발견되는 양성 연조직 종양이다. 대개 외상과 관련된 병력이 있으며 10대와 20대에서 호발하며 외과적 절제 후 재발은 드문 것으로 보고되었다. 14세 여아가 구개에 생긴 연조직 병소의 진단과 처치를 위해 서울대학교병원 소아치과로 의뢰되었다. 병소는 지난 6개월간 점차 크기가 증가하였으며 외상병력과 구강 내 악습관은 없는 것으로 조사되었다. 임상 검사 결과 직경 3cm의 무증상인 점막의 경상 융기가 관찰되었고, 생검(biopsy) 결과 섬유종으로 진단하였다. 외과적 제거 후 4년간 재발의 징후는 보이지 않았다. 섬유종에 대한 병리학적 고찰과 감별진단, 증례의 진단과 처치에 대해 보고하는 바이다.

• Clinical and Experimental Pediatrics
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• 제52권5호
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• pp.603-606
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• 2009

Pierre Robin sequence (PRS)는 소악증, 구개열, 설하수 및 고궁구개 등의 기형을 합병한 선천성 질환으로, 수유 장애 및 호흡 곤란 소견을 보이는 증후군이다. PRS과 관련된 염색체 핵형 분석 결과가 보고되면서, 유전학적 관련성이 제시되어 왔으나, 아직까지 명확히 규명되지 않은 상태이다. 이에 저자들은 PRS 환아에서 처음으로 핵형 46, XX, dup(8)(p21.3p23.1)를 보인 환아를 경험하고, 전염색체탐색자 분석을 통해 중복된 물질이 8번 염색체임을 확인하였으며, PRS와 8번 삼염색체성과의 관련성을 보고하는 바이다.