• RED RIBBON
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• s.53
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• pp.8-11
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• 2003

모든 HIV 감염자는 구강질환을 적어도 한가지 이상 가지고 있는데, 그 범위는 양성질환에서 중증질환 및 사망에 이르는 치명적인 상태에 이르기까지 다양하다.

• Journal of Oral Medicine and Pain
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• v.35 no.2
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• pp.101-110
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• 2010

Helicobacter pylori(H. pylori) is bacterial infection, with more than half of the world population infected and oral cavity is considered second reservoir of H. pylori infection. The purpose of this study was to evaluate role of oral cavity in H. pylori infection by comparison of the mode H. pylori infection in oral cavity and stomach. We recruited 100 subjects without systemic disease including gastrointestinal disease. Samples in oral cavity taken on gingival sulcus fluid(GSF) of lower left central incisor and 1st molar, area of buccal mucosa, dorsum of the tongue, palatal and saliva. We analyzed by Nested polymerase chain reaction(PCR) for oral infection and Urea Breath Test(UBT) for gastric infection. The results were as follows : 1. Among these 100 subjects, 36(36%) were positive by Nested PCR and 33(33%) were positive by UBT(p>0.05). 2. In detection rate of H. pylori in sites taken sample, 11(11%), 8(8%), 9(9%), 3(3%), 9(9%), 7(7%) were positive on GSF of lower left central incisor and 1st molar, area of buccal mucosa, dorsum of the tongue, palatal and saliva, respectively. Statical significance was observed in samples of GSF of lower left central incisor and area of dorsum of the tongue(p<0.05). 3. In comparison of the mode of H. pylori infection in oral cavity and stomach by analytic method, positive in oral cavity and stomach was 10(10%), negative in oral cavity and positive in stomach was 23(23%), positive in oral cavity and negative in stomach was 26(26%) and negative in oral cavity and stomach was 41(41%)(p>0.05). Conclusively, we can guess that oral H. pylori is not associated with gastric H. pylori infection and normal flora.

• Journal of Oral Medicine and Pain
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• v.34 no.1
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• pp.1-9
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• 2009

Liver transplantation is definitive treatment for the patients suffering from hepatitis, severe liver cirrhosis and liver cancer. In these patients, systemic infections under immunosuppression may occur easily. Therefore, primary object of dental treatments before liver transplantation is absolute removal of oral infection source. In addition, comprehensive dental management plan is essential for success of liver transplantation. The present study has been performed to investigate decayed, missing and filled permanent teeth index(DMFT index), degree of oral hygiene, past medical history, need of dental treatment, completion of dental treatment need and time interval between dental visit and operation date of liver transplantation in liver transplant candidates. Obtained results were as follows; 1. Decayed teeth of the patients were 2.68, missing teeth were 4.02 and filled teeth were 3.42. DMFT index was 10.12. 2. Twenty percents of patients showed moderate to severe food impactions, 42.2% of patients had moderate to heavy calculus and 37.8% of patients displayed gingival inflammation with swelling. 3. Patients needed periodontal treatments more than any other dental treatments. Periodontal treatments were needed for 88.9% of patients, operative & endodontic treatments were 46.7% of patients and 33.3% of patients needed for oral & maxillofacial surgical treatments. 4. Among 90 patients, time interval between scheduled operation date of liver transplantation and dental visit was within 2 weeks for 32.2% of patients, within 1 week for 20.0% of patients. In conclusion, most liver transplant candidates needed dental treatments for removal of potential infection sources. However because of insufficient interval between dental visit and operation date, they had taken liver transplantation procedures without comprehensive dental management. Development of preventive and comprehensive dental management program is mandatory for these patients. Cooperative interdisciplinary management will play a positive role for successful liver transplantation.

• Journal of Oral Medicine and Pain
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• v.17 no.2
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• pp.109-117
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• 1992

저출력레이저는 인체조직에 biostimulation effects를 가지므로 구강주위에 발생하는 여려가지 질병에 대한 저출력레이저광의 효과에 관하여 많은 연구가 시도되고 있으며 또한 치료에 응용되고 있다. 감염창상에 저출력레이저 조사시 조직치유의 기전이 세균 성장에 의한 조직손상보다 주위 정상조직의 biostimulation effects가 우세하기 때문이라는 가설을 확인하고저 본 연구를 시행하였다. 백서 7마리를 레이저 조사군과 대조군으로 나누어 감염창상의 면적차이를 비교하여 다음고 같은 결론을 얻었다. 1. 저출력레이저 조사군에서 창상수축율이 현저히 높았다. 2. 부종의 빈도는 저출력레이저 조사시 뚜렷하게 감소하였다. 위의 사실로 보아 저출력레이저 조사시 감염창상의 치유촉진은 주위 정상조직의 biostimulation effect가 세균증식에 의한 조직의 손상보다 우세하기 때문이라는 가설을 확인할 수 있었다.

• 치위협보
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• s.110
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• pp.1-12
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• 2006

• The Journal of the Korean dental association
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• v.25 no.4 s.215
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• pp.335-345
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• 1987

협점막, 치은, 구순막, 혀, 경구개, 연구개 및 구강저등으로 구성된 구강점막은 다양한 형태의 외상성 자극, 면역반응 이상, 세균감염, 유해한 환경등으로 인해 여러가지 질환이 발생된다. 이러한 질환들은 만성적이고 다른 질환에 비하여 발생빈도가 낮으며 병인이 불확실한 특성을 가지고 있다. 구강점막에 발생되는 질환들은 다양하게 분류될 수 있지만 여기에서는 크게 수포성, 궤양성 질환과 백색 구강점막 질환으로 나누어 그중 비교적 호발하는 몇몇 질환들에 대해 기술한다.

• RED RIBBON
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• s.77
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• pp.7-8
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• 2007

• Journal of dental hygiene science
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• v.11 no.3
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• pp.265-272
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• 2011

The purpose of this study is to compare oral hygiene status between young adult group and older adult group and to suggest a pathway model of oral health level in self-assessed. Subjects were totally 80 people with young adult group and the older adult group. The data, which was collected by surveying for one month from July 1, 2010 to July 30, was analyzed with SPSS VERSION 19.0 and AMOS 19.0. Oral hygiene test and questionnaire survey were carried out from targeting. 1. The young adult group and older adult group had the same quality in oral health level score and living habit. 2. The oral hygiene status in young adult and older adult group was same in 7 items(58.33%) out of 12 items. 3. Oral health level score in self-assessed of young adult group could be explained with 34% by 3 variables. Older adult group could be explained with 26% by 2 variables. 4. In young adult, the fitness of path model was very good with 0.96 in CFI, 0.94 in TLI, and 0.00 in RMSEA. In older adults, the fitness of path model was very good with 1.00 in CFI, 1.15 in TLI, and 0.00 in RMSEA. This might imply if TMJ disorder level and number of infection is neglected in young aldults, mastication function will be significantly effected in older adults. Thus, development and management of health education program is needed based on self-assessment oral health level by young adults group and older adults group.

• Journal of Oral Medicine and Pain
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• v.33 no.1
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• pp.9-14
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• 2008

Helicobacter pylori(H. pylori) has been associated with the cause of peptic ulcer and gastric cancer. H. pylori infection occur mostly during childhood and increase by aging. In route of transmission, Oral cavity does important role. So we employed this study to elucidate route of transmission by detection of H. pylori in infant saliva. We investigated 20 infants aged below 10 years and 20 teens aged below 20 years as study group and 71 adults aged 20 and over years as control group. H. pylori DNA was isolated from 5(25%) infants aged below 10 years, 6(30%) teens and 17(23.9%) adults by nested polymerase chain reaction(n-PCR). There was no statistically significant difference(P>0.05). The obtained results suggest that H. pylori infection is relatively common in saliva of Korean infant and oral cavity may be reservoir of H. pylori.

• Journal of Oral Medicine and Pain
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• v.33 no.1
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• pp.27-33
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• 2008

Candidiasis, an opportunistic infectious condition caused by the genus Candida, is the most common oral fungal infection in humans. The diagnosis of oral candidiasis can often be made based on recognition of its clinical pattern, but at times there is difficulty in making a clinical diagnosis because of its various manifestations. Several antifungal medications have been developed for managing fungal infections. Despite the availability of several effective antimycotics for the treatment of oral candidiasis, failure of therapy is not uncommon due to the unique environment of the oral cavity, where the flushing effect of saliva and the cleaning action of the oral musculature tend to reduce the drug concentration to sub-therapeutic levels. In this case report, we present two patients diagnosed with chronic hyperplastic candidiasis and median rhomboid glossitis, which are known as rare forms of candidiasis. In both cases, there was a significant reduction of clinical signs and symptoms when fluconazole was prescribed after the failure of initial nystatin therapy.