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Detection of Helicobacter Pylori in Saliva of Korean Infant  

Ryu, Ji-Won (Department of Oral Medicine, College of Dentistry, Chosun University)
Lee, Jang-Keun (Department of Oral Medicine, College of Dentistry, Chosun University)
Lee, Yong-Su (Department of Oral Medicine, College of Dentistry, Chosun University)
Yoon, Chang-Lyuk (Department of Oral Medicine, College of Dentistry, Chosun University)
Ahn, Jong-Mo (Department of Oral Medicine, College of Dentistry, Chosun University)
Publication Information
Journal of Oral Medicine and Pain / v.33, no.1, 2008 , pp. 9-14 More about this Journal
Abstract
Helicobacter pylori(H. pylori) has been associated with the cause of peptic ulcer and gastric cancer. H. pylori infection occur mostly during childhood and increase by aging. In route of transmission, Oral cavity does important role. So we employed this study to elucidate route of transmission by detection of H. pylori in infant saliva. We investigated 20 infants aged below 10 years and 20 teens aged below 20 years as study group and 71 adults aged 20 and over years as control group. H. pylori DNA was isolated from 5(25%) infants aged below 10 years, 6(30%) teens and 17(23.9%) adults by nested polymerase chain reaction(n-PCR). There was no statistically significant difference(P>0.05). The obtained results suggest that H. pylori infection is relatively common in saliva of Korean infant and oral cavity may be reservoir of H. pylori.
Keywords
H. Pylori infection; Infant; Saliva;
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