• The Korean Journal of Blood Transfusion
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• v.29 no.3
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• pp.320-327
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• 2018

A 72-year-old man with general weakness visited the outpatient clinic of the hematology department. The patient had been treated under the diagnosis of autoimmune hemolytic anemia for 2 years. His hemoglobin level at the time of the visit was 6.3 g/dL, and a blood transfusion was requested to treat his anemia. The patient's blood type was A, RhD positive. Antibody screening and identification test showed agglutination in all reagent cells with a positive reaction to autologous red blood cells (RBCs). He had a prior transfusion history with three least incompatible RBCs. The patient returned home after receiving one unit of leukoreduced filtered RBC, which was the least incompatible blood in the crossmatching test. After approximately five hours, however, fever, chills, dyspnea, abdominal pain, and hematuria appeared and the patient returned to the emergency room next day after the transfusion. The $anti-Fy^a$ antibody, which was masked by the autoantibody, was identified after autoadsorption using polyethylene glycol. He was diagnosed with an acute hemolytic transfusion reaction due to $anti-Fy^a$ that had not been detected before the transfusion. In this setting, it is necessary to consider the identification of coexisting alloantibodies in patients with autoantibodies and to become more familiar with the method of autoantibody adsorption.

• Journal of the korean academy of Pediatric Dentistry
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• v.46 no.2
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• pp.147-157
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• 2019

This study aimed to evaluate skeletodental characteristics of patient with maxillary lateral incisor agenesis (MLIA) in mixed dentition. It involved the children in early mixed dentition who visited Pusan National University dental hospital for orthodontic purposed and had intact primary canines. 38 children with MLIA and 38 controls with the same chronological age satisfying the inclusion criteria were selected. The craniofacial structures and dental arch dimensions of the MLIA were evaluated using model & cephalometric analysis and compared to controls. The rate of unilateral MLIA was high in male and the rate of bilateral MLIA was high in female. In model analysis, the width / length ratio of maxillary anterior portion of the MLIA group were higher and arch perimeter of the maxilla of the MLIA group were smaller than those of the control group (p = 0.003, 0.04). Cephalometric analysis showed that there were no significant differences in terms of skeletal, dental analysis. In soft tissue profile, nasolabial angle was larger in MLIAs than in controls (p = 0.039). Considering these skeletodental characteristics of MLIA, early diagnosis and proper management is highly recommended to minimize the possibility of functional defect.

• Korean Journal of Clinical Laboratory Science
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• v.52 no.4
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• pp.417-424
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• 2020

This study aimed to explore the effects of brain-derived neurotrophic factor (BDNF), produced by engineered immortalized mesenchymal stem cells (imMSC), on lower urinary tract symptoms (LUTS) in a rat model with neurogenic bladder (NB). Forty-eight Sprague-Dawley (SD) rats were randomly divided into the following groups: Sham control, LUTS, LUTS+imMSC (treated with immortalized MSC), and LUTS+BDNF-eMSC (treated with BDNF-expressing MSC) groups. LUTS was induced by a crush injury to the major pelvic ganglion (MPG). Bladder function was tested under anesthesia, and bladder tissue strips were collected thereafter for contractility test and western blot analysis. Western blot results showed that the expression of both Angiopoietin 1 (Ang 1) and platelet-derived growth factor (PDGF) increased with MSC injection. The effect of treatment with BDNF-eMSC on LUTS was also evaluated, and the results were found to be better than those with imMSC (P<0.05). BDNF-eMSC prevented fibrosis in the bladder tissue and significantly reduced caspase-3 levels. In conclusion, high expression of BDNF in vivo resulted in recovery of bladder function and contractility, along with the inhibition of apoptosis in a rat model.

• Journal of Korea Entertainment Industry Association
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• v.14 no.3
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• pp.383-392
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• 2020

This study was to compare the effects of joint mobilization, treadmill with insole, and joint mobilization and treadmill with insole on pain, pelvic angle, and foot pressure in patients with sacroiliac joint pain. 24 patients randomly assigned to joint mobilization group(n=8), treadmill with insole group(n=8), or joint mobilization and treadmill with insole group(n=8). Each groups were conducted 30 minutes a day, two days a week for four weeks. Pain was evaluated using visual analogue scale and pelvic angle was measured using palpation meter and foot pressure(fore/rear ratio) was measured using Gateview AFA-50 before intervention and after 4 weeks. All groups were significant differences pain in intragroup(p<.01). In pelvic angle, the joint mobilization group was statistically significant in the anterior tilt only, the joint mobilization and treadmill with insole group showed statistically significant improvement in both anterior and posterior tilt(p<.01), and the treadmill with insole group did not show any statistically significant change(p>.05). Also the joint mobilization and treadmill with insole group were significant differences in foot pressure(p<.01). All the interventions reduce sacroiliac joint pain and joint mobilization and treadmill with insole training are most effective changes in pelvic angle and foot pressure. This study can be used as a basic data for prevention of injury, posture correction and gait training in patients with sacroiliac joint pain, as well as chronic low back pain and plantar pressure problem.

• Journal of Korea Entertainment Industry Association
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• v.15 no.1
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• pp.191-197
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• 2021

This study studied the effect of visual difference on balance and walking ability in college students' life care. The study was conducted on 45 students attending H University in G City, divided into control groups (n=22, not wearing glasses and contact lenses) and experimental groups (n=23, wearing glasses and contact lenses). In not wearing glasses and contact lenses, the subjects measured visual acuity with logMAR charts, evaluated their balance ability with BIOrescue, and evaluated walking ability with G-Walk. The results of this study showed that the experimental group had statistically significantly lower vision than the control group in the visual acuity measurement(p<.01). Static balance ability was statistically significant increase in center of mass movement of the right foot in the experimental group compared to the control group(p<.05). Dynamic balance ability was statistically significantly reduce in limit of stability for groups of experiments compared to control group(p<.05). The walking ability was statistically significantly shorter on step length and stride length, swing of the experimental group compared to the control group in the right foot(p<.05). The findings showed that the visual difference in university students reduces balance and walking ability. Therefore, university students with poor visual acuity are recommended to correct of visual acuity to prevent collision and falls in their daily lives.

• Journal of The Korean Society of Integrative Medicine
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• v.10 no.1
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• pp.13-26
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• 2022

Purpose : The purpose of this study was to investigate the effect of Dang Dang integrated corrective therapy including myofascial release, chuna therapy, and exercise therapy on height, muscle mass, body fat, and body water in patients with body imbalance. The secondary aim was to investigate whether the percent of change in height, muscle mass, body fat, and body water varied by age group. Methods : In total, 279 patients with body imbalance between the ages of 10 and 79 were recruited at hospitals. All participants had Dang Dang integrated corrective therapy including myofascial release, chuna therapy, and exercise therapy. The patients' height, muscle mass, body fat, and body water were measured before and after Dang Dang integrated corrective therapy using InBody. Results : The height, muscle mass, and body water significantly increased after Dang Dang integrated corrective therapy in all age groups except for the 70~79 age group and body fat significantly decreased (p < .05). The age group comparison of the percent change in height, muscle mass, and body water showed significant differences (p < .05). In the post hoc test, the percent change of height in the 10~19 age group was significantly greater than in the other age groups except for the 70~79 age group. The percent change of muscle mass and body water in the 10~19 age group was significantly greater than in the 30~39 age group. Conclusion : These findings suggest that applying Dang Dang integrated corrective therapy to patients with body imbalance, excluding patients aged 70~79, may be a useful method to increase height, muscle mass, and body water and decrease body fat through spinal and joint realignment. The best results were observed in teenagers.

• Journal of the korean academy of Pediatric Dentistry
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• v.49 no.1
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• pp.25-34
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• 2022

This study aimed to investigate a quantitative analysis of the anatomical characteristics of the maxillary supernumerary lateral incisor and its relationship with lateral incisors. Forty-four supernumerary lateral incisors from 43 patients were evaluated for analyzing the position, shape, direction, and relationship between the supernumerary lateral incisor and the normal lateral incisors, using cone-beam computed tomography (CBCT). To compare the size of crown, the mesio-distal width was measured and the Nolla stage was used for evaluating the degree of root development to compare tooth maturity. The supernumerary lateral incisors were in the normal direction at a rate of 90.9%, and in a supplemental shape at a rate of 84.1%. The supernumerary lateral incisor was smaller in size compared to the adjacent lateral incisor and opposite lateral incisor (p < .0001). There was no statistically significant difference in the development stage of root. Based on these results, the supernumerary lateral incisor is similar with the lateral incisor, but has a difference in the size of crown. It is necessary to distinguish the supernumerary lateral incisor from the lateral incisor precisely to reduce clinical complications.

• Journal of Nutrition and Health
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• v.55 no.5
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• pp.572-586
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• 2022

Purpose: This study examined the factors that may affect the growth status of preterm infants. Methods: This study included 91 preterm infants born at <37 weeks of gestation (22.9-36.9 weeks of gestation), including 48 (52.7%) males and 43 (47.3%) females. Diet-related data were collected through parental questionnaires, and growth-related data, such as height and weight, were collected through the hospital medical records. Results: No significant difference in weight and growth was observed between early and late preterm infants. On the other hand, smaller averages of all weight z-score (recent weight at 40 weeks of gestation) included lower birth weight, height, and head circumference. On the other hand, infants' birth weight, height, and head circumference in the weight z-score of <0 (<50% in the age-weight growth chart) was smaller than those in the weight z-score of ≥0. Furthermore, neonatal intensive care unit (NICU) hospitalization period and NICU discharge were shorter with growth cessation age in weight z-score of <0. The weight growth velocity was associated with gestational age, birth weight, and medical treatment in the NICU. Thus, parents of preterm infants with low growth rates prefer more community care services for their children. Conclusion: Birth weight, age of preterm infants, and medical treatment in the NICU were factors related to early birth weight growth. Following NICU discharge, poor intake and intake issues were associated with poor growth after 40 weeks of gestation. Therefore, monitoring the growth of preterm infants requires continuous active involvement and supports for growth-promoting factors after NICU discharge.

• The Journal of Korean Academy of Prosthodontics
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• v.61 no.2
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• pp.125-134
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• 2023

When the patient with class III malocclusion needs extensive oral rehabilitation due to multiple missing teeth, accurate diagnosis, and careful analysis, such as the patient's occlusal relationship, facial changes, and evaluation of the temporomandibular joint are essential. Orthognathic surgery is often performed for aesthetic improvement, depending on the patient's chief complaint. If it is not possible due to certain circumstances, partial aesthetic improvement can be achieved through minimal elevation of the vertical dimension. As this patient may have unexpected issues, such as temporomandibular joint disorder, oral habits like bruxism, and masticatory muscle tension, it was determined whether the patient could adjust to a reversible temporary removable partial denture. After this, the maxillary implant-supported fixed prostheses and the mandibular fixed prostheses were used to achieve stable posterior support and to partially improve the maxillary anterior esthetics. The patient was satisfied with the results both aesthetically and functionally. The prognosis is expected to be good if regular check-ups are conducted.

• Journal of the Korean Orthopaedic Association
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• v.54 no.2
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• pp.192-196
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• 2019

Iatrogenic calcinosis cutis is due to the intravenous administration of calcium gluconate or calcium chloride to treat hypocalcemia. The arthors report three cases of calcinosis cutis with calcifications involving the upper or lower extremities in neonates following the extravasation of calcium gluconate. Three neonates, a 2-week-old girl, 4-week-old boy, and a 4-week-old girl, were consulted for indurated nodules after the intravenous administration of calcium gluconate at the intensive care unit. Complete remission of palpable nodule and calcification was observed on the radiograph at three weeks, four weeks and six months after the initial presentation in each. All three neonates with iatrogenic calcinosis curtis were resolved spontaneously without functional and cosmetic complications. According to enhancement of the patient's cognition about benign disease, a suitable explanation of the disease and avoiding unnecessary treatment through an early diagnosis of iatrogenic calcinosis cutis will reduce a number of potential medical malpractice disputes.