• 제목/요약/키워드: 교정곡선

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Evaluation of Myocardial Oxygen Consumption with $^{11}C$-Acetate and 3D PET/CT: By Applying Recirculation Correction Method and Modified One-Compartmental Tracer Kinetic Modeling ($^{11}C$-Acetate와 3차원 PET/CT를 이용한 심근의 산소 소모량 평가: 재순환 교정법 및 수정 단일구획 추적자 동적 모델 적용)

  • Chun, In-Kook;Hwang, Kyung-Hoon;Lee, Sang-Yoon;Kim, Jin-Su;Lee, Jae-Sung;Shin, Hee-Won;Lee, Min-Kyung;Yoon, Min-Ki;Choe, Won-Sick
    • Nuclear Medicine and Molecular Imaging
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    • v.42 no.4
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    • pp.275-284
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    • 2008
  • Purpose: We intended to evaluate myocardial oxygen consumption ($MVO_2)$ by applying recirculation correction and modified one-compartment model to have a reference range of $MVO_2$ in normal young population and to reveal the effect of recirculation on time-activity curve (TAC). Materials and Methods: In nine normal male volunteers with mean age of $26.3{\pm}4.0$, $MVO_2$ was estimated with 925 MBq (25mCi) of $^{11}C$-Acetate (Neuroscience Research Institute, Gachon University of Medicine and Science, Incheon, Korea) and PET/CT (Biograph 6, Siemens Medical Solution, Germany). Analysis software such as $MATLAB^{(R)}$ v7.1 (Mathworks, Inc., United States), $Excel^{(R)}$ 2007 (Microsoft, United States), and $SPSS^{(R)}$ v12.0 (Apache Software Foundation, United States) were used. Twenty three frames were of $12{\times}10$, $5{\times}60$, $3{\times}120$, $2{\times}300's$ duration, respectively. The modified one-compartmental model and the recirculation correction method were applied. Statistical analysis was performed by using Test of Normality, ANOVA and Post-Hoc (Scheffe's) analysis, and p-value less than 0.05 was considered as significant. Results: The normal reference ranges of $MVO_2$ were presented as $3.18-4.64\;{\times}\;10^{-4}\;ml/g/sec$, $1.91-3.94\;{\times}\;10^{-4}\;ml/g/sec$, $4.31-6.40\;{\times}\;10^{-4}\;ml/g/sec$, $2.84-4.53\;{\times}\;10^{-4}\;ml/g/sec$ and $3.42-5.00\;{\times}\;10^{-4}\;ml/g/sec$ in the septum, the inferior wall, the lateral wall, the anterior wall and the entire wall, respectively. In addition, it was noted that the dual exponentiality of the clearance curve is due to the recirculation effect and that the characteristic of the curve is essentially mono-exponential. Conclusion: $^{11}C$-Acetate is a radiotracer worthwhile to assess $MVO_2$. Re-circulated $^{11}C$ can influence TAC of $^{11}C$ in myocadia and so the recirculation correction must be considered when measuring $MVO_2$.

The new approach to maxillary and mandibular anterior dental arch forms - In Korean normal occlusion models (상하악 전치부 치열궁 형태에 대한 새로운 접근 - 한국성인 정상교합자 모델에서)

  • Ha, Man-Hee;Son, Woo-Sung;Yang, Hoon-Chul
    • The korean journal of orthodontics
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    • v.31 no.3 s.86
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    • pp.347-355
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    • 2001
  • Maxillary and mandibular anterior dental arches often have the problems of occlusal relation and esthetics by malformations of teeth, congenital missing, et at. Though the clinician usually use the anterior ratio to overcome this problems, he has the limitation of a direct application this ratio to the prediction of anterior occlusal relationship by the change of anterior ratio as dental arch form, intercanine width, segment depth and arch perimeter. So this study examine maxillary and mandibular anterior dental arch forms by least square method using Korean normal occlusion models(man : 20 casts, woman : 20 casts). Maxillary and mandibular anterior dental arches of Korean normal occlusion models are curve fitted to polynomial function, beta function, hyperbolic cosine function in order. And this accuracy of curve fitting is constant regardless of man/woman and maxilla/mandible. The relationships between intercanine width, segment depth, and arch perimeter based on this owe fitted dental arch form are acquired. This relationships will give the prediction of anterior dental arch form and the information of more accurate anterior ratio according to intercanine width.

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Load-deflection characteristics and plastic deformation of NiTi closed coil springs (수종의 니켈-티타늄 폐쇄형 코일 스프링의 하중-변위 특성 및 소성 변형 비교)

  • Son, Ah-Young;Lim, Sung-Hoon
    • The korean journal of orthodontics
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    • v.39 no.5
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    • pp.310-319
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    • 2009
  • Objective: NiTi closed coil springs were reported to have relatively constant unloading forces. However, the characteristics of NiTi closed coil springs from various manufacturers have not been elucidated. The purpose of this study was to compare load-deflection characteristics of various NiTi closed coil springs and to find out the optimal range of extension. Methods: Seven kinds of NiTi closed coil springs from five manufacturers were tested. Load deflection curves were obtained at extension ranges from 2 mm to 30 mm. Also, springs were kept extended during a 4 week period, and then load deflection curves were obtained again. Results: Sentalloy (Tomy) and Jinsung blue (Jinsung) showed superelasticity in every extension ranges tested and showed plastic deformation of less than 1 mm. Ni-Ti (Ormco) showed superelasticity only after the springs were extended at or more than 10 mm, thereby meaning that clinicians should extend these springs at or more than 10 mm to utilize the superelasticity. Orthonol (RMO) and Nitanium (Ortho Organizers) did not show superelasticity. After 4 weeks of extension, all springs showed plastic deformation less than 1 mm when the extension was at or under 25 mm. Conclusions: The superelastic behavior of NiTi closed springs were different among various NiTi spring products, and some NiTi closed springs failed to show superelasticity.

Measurement of combustor surface temperature using phosphor thermometry (형광체를 이용한 연소기 표면온도 측정기술)

  • Kim, Yong-Gyoo;Lee, Seok Hwan;Kim, Sunghun;Yang, Inyoung
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2017.05a
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    • pp.228-231
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    • 2017
  • The surface temperature of a combustor such as an aircraft engine is one of the important measuring factors related to the combustion performance. However, a conventional temperature measurement technique have a large measurement error due to a bad environment such as a combustion flame, vibration, and dust. In order to solve this problem, a technology has been developed which can measure the surface temperature of the combustor in real time using the wavelength change or attenuation time change according to the temperature of the phosphor. In this study, we developed a technique that can measure surface temperature of scram-jet combustor using phosphor thermometry. The calibration curve was obtained according to the temperature from $200^{\circ}C$ to $800^{\circ}C$ in the calibrated temperature chamber. So, we confirmed that phosphor thermometry can be used for measuring surface temperature of scram-jet combustor.

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Comparative study on experimental measurements of discharge using various flow meters (유속측정 기기별 측정성과에 대한 실험적 비교분석)

  • Lee, Jae-Hyug;Kang, Kyang-Min;Jung, Sung-Won;Kim, Tae-Woong
    • Proceedings of the Korea Water Resources Association Conference
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    • 2009.05a
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    • pp.1908-1912
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    • 2009
  • 유량자료는 물의 순환과정을 규명하고 효율적인 수자원 개발 및 이수 치수 계획 등에 매우 귀중하게 이용된다. 그러나 이러한 유량자료를 확보하는 데는 많은 시간과 경비 등이 요구되기 때문에 주요 수위의 유량측정자료로 수위-유량관계 곡선식(Stage-Discharge Curve)을 개발하여 유량자료를 환산하고 있다. 따라서 수위-유량관계 곡선식의 신뢰도는 유량자료의 품질에 절대적인 영향을 미치는 요인으로 작용된다. 수문학을 연구하는 많은 학자들은 고품질의 유량자료를 생산하여 신뢰성 있는 곡선식을 개발하고자 유량측정 방법과 기준, 장비개량 등에 관한 연구를 수행하고 있다. 측정하고자 하는 기기별 측정 성과에 대한 연구 자료가 거의 없이 국내에 보급된 다양한 유속측정기기를 사용하여 유량자료를 생산하여 활용하고 있다. 본 연구에서는 규격화된 콘크리트 수로에 일정한 유량을 흘려보내고 다양한 측정기기를 이용하여 유속을 측정하였다. 그리고 이 측정성과를 이용하여 유량을 산정하고 비교분석하였다. 실험을 위해서 국내에서 일반적으로 사용되고 있는 측정기기로 마그네틱유속계(Electromagnetic Current Meter), 휴대용유량계(Flow Meter), 프라이스유속계(USGS Type AA Current Meter), 갈수기용유속계(USGS Pygmy Meter)등의 장비를 사용하였으며, 동일한 조건에서 유량을 얻음으로 측정 기기가 제시하는 유량을 알 수 있었다. 비교검토에 적용하고자 측정한 수심으로는 0.25m, 0.30m, 0.35m, 0.40m의 4개 Case로 진행이 되었으며, 측정방법으로는 도섭법(Wading Measurement)에 의하거나 케이블웨이(Cableway), 교량법(Bridge Measurement), 보트법(Boat Measurement)등이 있으나, 신뢰성과 정확도를 높이기 위해 도섭법으로 수면에서 0.6d 지점의 유량측정방법(1점법)을 적용하였다. USGS Type AA Current Meter, USGS Pygmy Meter는 유속측정기기의 검교정을 받았으므로 다른 실험유속측정치의 비교를 위한 기준값으로 사용하였다. 따라서 국내에서 널리 사용되는 측정기기(Electromagnetic Current meter, Flow Meter, USGS Type AA Current Meter, USGS Pygmy Meter)별 검토 결과 프라이스유속계를 기준으로 마그네틱유속계는 ${\pm}$10% 이상, 갈수기용 유속계 및 휴대용 유량계는 ${\pm}$5% 미만의 차이가 있음을 확인할 수 있었다.

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A Case of Biphasic Flow-volume Loop in Left Mainstem Bronchial Stenosis (이상성 기류유량곡선(biphasic flow-volume loop)을 보인 결핵에 기인한 좌주기관지협착 1예)

  • Choi, Soo-Jeon;Jo, Moon-Suk;Lee, Hyuk-Pyo;Kim, Joo-In;Yum, Ho-Kkee
    • Tuberculosis and Respiratory Diseases
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    • v.45 no.2
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    • pp.416-420
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    • 1998
  • Flow-volume loop is known to be useful in the diagnosis of upper airway obstruction. In cases of tracheal obstruction, characteristic features such as fixed or variable upper airway obstruction patterns give clue to the diagnosis. But the flow-volume loop of unilateral mainstem bronchial stenosis is not known well. There is controversy in patterns of flow-volume loop in unilateral mainstem bronchial stenosis (restrictive pattern or biphasic pattern). We report a case of biphasic flow-volume loop in left mainstem bronchial stenosis(4-5 mm in diameter) as a sequela of endobronchial tuberculosis, which recovered normal flow-volume loop after metallic stent insertion and 2 months later showed reappearance of biphasic pattern because of restenosis of left mainstem bronchus due to growth of granulation tissue at the stent site.

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Catch up growth in children born small for gestational age by corrected growth curve (부당 경량아로 출생한 소아들에서 교정성장곡선을 이용한 따라잡기 성장에 대한 연구)

  • Jung, Myung Ki;Song, Ji Eun;Yang, Seung;Hwang, Il Tae;Lee, Hae Ran
    • Clinical and Experimental Pediatrics
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    • v.52 no.9
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    • pp.984-990
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    • 2009
  • Purpose : Being small for gestational age (SGA) is a risk factor of short stature in children. Genetic background such as mid-parental height (MPH) is known to influence growth of children born SGA. We studied the relationship between growth of children born SGA and MPH and studied the effects of insulin-like growth factor (IGF-I) and insulin-like growth factor binding protein 3 (IGFBP-3) on postnatal growth in children born SGA according to MPH. Methods : Forty-nine neonates born SGA were included in this study. We defined corrected height standard deviation score (cHtSDS) by modified height SDS (HtSDS) based on their MPH. We categorized subjects into group 1 consisting of children with cHtSDS ${\geq}0$ (n=35) and group 2 consisting of children with cHtSDS <0 (n=14), and compared IGF-I and IGFBP-3 between the two groups. Results : The HtSDSs and cHtSDSs in groups 1 and 2 were $0.06{\pm}1.05$ vs. $-0.95{\pm}0.85$ (P=0.000) and $0.78{\pm}0.93$ vs. $-0.46{\pm}0.67$ (P=0.000), respectively. IGF-I SDS was higher in group 1 than in group 2 ($2.82{\pm}3.69$ vs. $0.23{\pm}2.42$, P=0.012). Total cHtSDS ($0.42{\pm}1.03$) was significantly higher than HtSDS ($-0.22{\pm}1.10$) (P=0.000). Conclusion : Our results show that cHtSDS differs significantly from HtSDS. Growth assessment by standardized growth curve does not uniformly show effects of genetic factors. A more accurate assessment of growth uses a personalized corrected growth curve that considers the genetic factor measured by MPH.

Generation of calibration standard gases using capillary gas divider: uncertainty measurement and method validation (다중 모세관을 이용한 교정용 표준가스의 제조: 불확도와 유효성 평가)

  • Lee, Sangyun;Hwang, Eun-Jin;Jung, Hye-Ja;Lee, Kwang-Woo;Chun, Ki-Joon
    • Analytical Science and Technology
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    • v.19 no.5
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    • pp.369-375
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    • 2006
  • Calibration gas mixtures were prepared using dynamic volumetric method according to ISO 6145-5 and the uncertainty was evaluated. Ten identical capillaries with 0.25 mm in inner diameter and 50 cm in length were applied in this system. Dilution ratio of parent gas was determined by the number of capillaries that passes parent gas and that passes balance gas through. Capillaries were made of Teflon which had good chemical stability against adsorption of gaseous substances. Mechanical valves were introduced in this system in order to minimize the thermal effect of solenoid valves. Concentration of prepared gases were compared with master grade standard gases in cylinders made by RiGAS Co. and calibration of the instrument were completed using comparison method according to ISO 6143. Experimental results showed that the coefficient of variance of diluted oxygen standard gases showed less then 0.2% in most dilution range, that of diluted hydrogen sulfide standard gases showed less then 1.0%. Therefore, it is proven that the standard gases prepared by this system are appropriate to be used as a calibration standards in ambient monitoring, etc.

Feasibility Study of Dose Evaluation of Stereotactic Radiosurgery using GafChromic $EBT^{(R)}$ Film (GafChromic $EBT^{(R)}$ 필름을 이용한 뇌정위방사선치료의 선량분석 가능성 평가)

  • Jang, Eun-Sung;Lee, Chul-Soo
    • The Journal of Korean Society for Radiation Therapy
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    • v.19 no.1
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    • pp.27-33
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    • 2007
  • Purpose: We have performed SRS (stereotactic radiosurgery) for avm (arterry vein malformation) and brain cancer. In order to verify dose and localization of SRS, dose distributions from TPS ($X-Knife^{(R)}$ 3.0, Radionics, USA) and GafChromic $EBT^{(R)}$ film in a head phantom were compared. Materials and Methods: In this study, head and neck region of conventional humanoid phantom was modified by substituting one of 2.5 cm slap with five 0.5 cm acrylic plates to stack the GafChromic $EBT^{(R)}$ film slice by slice with 5 mm intervals. Four films and five acrylic plates were cut along the contour of head phantom in axial plane. The head phantom was fixed with SRS head ring and adapted SRS localizer as same as real SRS procedure. CT images of the head phantom were acquired in 5 mm slice intervals as film interval. Five arc 6 MV photon beams using the SRS cone with 2 cm diameter were delivered 300 cGy to the target in the phantom. Ten small pieces of the film were exposed to 0, 50, 100, 200, 300, 400, 500, 600, 700, 800, 900 cGy, respectively to calibrate the GafChromic $EBT^{(R)}$ film. The films in the phantom were digitized after 24 hours and its linearity was calibrated. The pixel values of the film were converted to the dose and compared with the dose distribution from the TPS calculation. Results: Calibration curve for the GafChromic $EBT^{(R)}$ film was linear up to 900 cGy. The R2 value was better than 0.992. Discrepancy between calculated from $X-Knife^{(R)}$ 3.0 and measured dose distributions with the film was less than 5% through all slices. Conclusion: It was possible to evaluate every slice of humanoid phantom by stacking the GafChromic EBT film which is suitable for 2 dimensional dosimetry, It was found that film dosimetry using the GafChromic $EBT^{(R)}$ film is feasible for routine dosimetric QA of stereotactic radiosurgery.

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Comparative Measurement of Radioactivity with Standard Gamma-ray Ionization Chamber System (표준 감마선 전리함 장치에 의한 방사능 비교 측정)

  • Park, Tae-Soon;Woo, Dong-Ho;Oh, Pil-Jae;Hwang, Sun-Tae
    • Journal of Radiation Protection and Research
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    • v.9 no.1
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    • pp.11-18
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    • 1984
  • A Standard gamma-ray ionization chamber system was developed with a well type ionization chamber and micro current measuring circuit. Micro current was measured by the automatic Townsend balance with stepwise compensation method. For gamma emitting nuclides such as $^{241}Am,\;^{133}Ba,\;^{60}Co,\;^{134}Cs,\;^{137}Cs,\;and\;^{22}Na$ relative calibration factors to $^{226}Ra$ reference source were calculated and detection .efficiency curve was determined as a fudnction of gamma energy.

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