• Title/Summary/Keyword: 관 파괴

Search Result 332, Processing Time 0.029 seconds

Shear Performance of Board-type Two-way Voided Slab (일체형 중공재의 중공부 내부형상에 따른 이방향 중공슬래브의 전단성능 평가)

  • Choi, Hyeon-Min;Park, Tae-Won;Paik, In-Kwan;Kim, Je-Sub;Han, Ju-Yeon
    • Journal of the Korea Concrete Institute
    • /
    • v.27 no.6
    • /
    • pp.651-659
    • /
    • 2015
  • Currently, social demands for long span building structures are increasing due to architectural planning purposes and economic efficiency. As a result, lighter board-type voiding materials were suggested. With the use of board-type voiding materials, a slab is able to become light weight and convenient. This process efficiently eliminates concrete where it is not required; considerably diminishing dead weight while maintaining the flexural strength of the slab. The reduction in concrete also allows for overall cost reductions and design flexibility. Also it can be ease with fixing the voided material that is composed of one body form. Although board-type voiding materials are ideal, the top and bottom concrete plates lack integrity. Because of this, test results show horizontal cracking towards the tops and bottoms of the concrete columns, or webs, connecting the slabs. The key to correcting this problem is to increase the shear strength. In order to increase the shear strength of the structure, horizontal shear area must increase. R70(100)-D-F has the largest horizontal shear area as it also shows stronger strength. As a result, shear strength ($V_{nh}$) is dependent on the horizontal shear area (N). $V_{nh}={\alpha}{\times}0.16{\sqrt{f_{ck}}}{\frac{{\pi}D^2}{4}}{\times}N({\alpha}=1.8125)$. The web columns have a shear span to depth ratio (a/d) that is less than 2; which classifies it as a deep beam. In this case, however, the shear strength of the deep beams may be as much as 2 to 3 times greater than that predicated conventional equations developed for members of normal proportions. As a result, ${\alpha}$ is suggested as an extra coefficient in the equation for shear strength ($V_{nh}$).

Effect of Astragalus Membranaceus Extract against Improvement of Myelosuppression and Quality of Life in 5-Fluorouracil Treated Mice (황기 추출물이 5-Fluorouracil을 투여한 생쥐의 골수억제 및 삶의 질에 미치는 영향)

  • Kwon, Chang-Hyun;Yoo, Hwa-Seung;Bang, Sun-Hwi;Lee, Young-Min;Lee, Yeon-Weol;Son, Chang-Gue;Cho, Chong-Kwan
    • The Journal of Internal Korean Medicine
    • /
    • v.28 no.2
    • /
    • pp.304-320
    • /
    • 2007
  • Objective : To evaluate the effect of Astragalus Membranaceus Extrac (AME) on myelosuppression, activity and immune modulation in 5-fluorouracil (5-FU) treated mice. Method : We carried out complete blood count, histological analysis of bone marrow, and cell colony forming assay for hematopoietic progenitor to evaluate the effect of AME on myelosuppression and conducted swimming test, survival rate, nitric oxide (NO) assay, 51Cr release assay in natural killer cell, mRNA expression of $IL-1{\beta}$, IL-2, IL-4, IL-6, IL-10, $TNF-{\alpht}$, $IFN-{\gamma}$, $TGF-{\beta}$ and GM-CSF in spleen cells to evaluate the effect of AME on quality of life (QOL). Results : AME improved 5-FU induced myelosuppression and peripheral blood count was recovered effectively, had significant efficacy to protect against chemotherapy induced marrow-destruction and on hematopoiesis compared with the control group, improved increase survival rate and the swimming time, had a stimulatory effect on macrophage activation and NK cell activity, and up-regulated cytokine gene transcription (IL-2, IL-6, $IFN-{\gamma}$) in murine immunologic system. Conclusion : We can conclude that AM is an effective herbal agent for improvement of myelosuppression and QOL in 5-FU treated mice.

  • PDF

A Comparative Study on the Mechanical Properties of Plywood treated with Several Fire-Retardant Chemicals(II) - Effect of Platen Temperature in Press Drying on the Static Bending Strength of Treated Plywood - (수종(樹種) 내화약제(耐火藥劑)로 처리(處理)된 합판(處理)의 기술적(技術的) 성질(性質)에 관(關)한 비교연구(比較硏究)(II) - 열판건조시(熱板乾燥時) 열판온도(熱板溫度)가 처리합판(處理合板)의 휨강도(强度)에 미치는 영향(影響) -)

  • Chung, Woo-Yang;Kim, Jong-Man;Lee, Phil-Woo
    • Journal of the Korean Wood Science and Technology
    • /
    • v.12 no.4
    • /
    • pp.12-18
    • /
    • 1984
  • Soaking treated in 20% aqueous solutions of $(NH_4)_2SO_4$, $NH_4H_2PO_4$, $(NH_4)_2HPO_4$, $Na_2B_4O_7-H_3BO_3$(60:40) and Minalith, the mixed salts for 9 hrs. the wet 3.5mm meranti (Parashorea spp.) plywoods were press-dried at 90, 120 and $150^{\circ}C$ and put to static bending test to examine the influence of redrying temperature on the strength of fire-retardant treated plywoods ill flexure. While water-soaking treatment (control) showed serious reduction in Stress at proportional limit, MOE, MOR, Work per unit volume at $150^{\circ}C$, all the fire-retardant treatments maintained bending strength even at $150^{\circ}C$ and showed rather increased values in case of some chemicals. In view of drying rate and maintenance of strength, the most pertinent platen temperature was $150^{\circ}C$ and Borax-Boric acid was the predominant fire-retardant in this study.

  • PDF

A study of Spatial Multi-Criteria Decision Making for optimal flood defense measures considering regional characteristic (지역특성을 고려한 홍수방어대안 제시를 위한 공간 다기준의사결정 기법 적용 방안 연구)

  • Lee, Eunkyung;Ji, Jungwon;Yi, Jaeeung
    • Journal of Korea Water Resources Association
    • /
    • v.51 no.4
    • /
    • pp.301-311
    • /
    • 2018
  • Recently, the flood inundation caused by heavy rainfall in urban area is increasing due to global warming. The variability of climate change is described in the IPCC 5th report (2014). The precipitation pattern and hydrological system is varied by climate change. Since the heavy rainfall surpassed the design capacity of the pipeline, it caused great damage in metropolitan cities such as Seoul and Busan. Inundation in urban area is primarily caused by insufficient sewer capacity and surplus overflow of river. Inundation in urban area with concentrated population is more dangerous than rural and mountains areas, because it is accompanied by human casualties as well as socio-economic damage to recover destruction of roads, brides and underground spaces. In addition, various factors such as an increase in impervious area, a short time of concentration to outlet, and a shortage of sewer capacity's lack increase flooding damage. In this study, flood inundation analysis was conducted for vulnerable areas using XP-SWMM. Also, three structural flood prevention measures such as drainage pipeline construction, detention reservoir construction, and flood pumping station construction are applied as flood damage prevention alternatives. The flood data for each alternative were extracted by dividing the basin by grid. The Spatial Compromise Programming are applied using flood assessment criteria, such as maximum inundation depth, inundation time, and construction cost. The purpose of this study is to reflect the preference of alternatives according to geographical condition even in the same watershed and to select flood defense alternative considering regional characteristics.

Electron Microscopic Study on the Role of Actin Filaments during the Formation of Bile Canaliculi in Isolated Rat Hepatocyte Culture System (흰쥐에서 분리 배양한 간세포의 담세관 형성에 있어서 액틴미세섬유의 역할에 관한 전자현미경적 연구)

  • Park, Chang-Hyun;Chang, Byung-Joon;Uhm, Chang-Sub
    • Applied Microscopy
    • /
    • v.29 no.4
    • /
    • pp.437-450
    • /
    • 1999
  • Bile canaliculi are the structure delivering bile secreted by hepatocytes into the bile passage. Bile secretion is mainly controlled by the cytoskeletal elements, mainly of actin in the microvilli, pericanalicular web. Most studies on the bile secretion have been done in viva situation, however, to control the various parameters in vitro culture system seem to be more useful. To set up an in vitro experimental system, the investigator isolated hepatocytes with an enzymatic method using a mixture of collagenase and hyaluronidase from normal Sprague-Dawley rat liver and cultured. Isolated hepatocytes were round and formed cords in culture. Microvilli covered the whole surface of hepatocytes. Bile canaliculi were formed between hepatocytes and were characterized by the presence of microvilli of various lengths and shapes mainly arising from small surface mounds. Actin filament core in the microvilli and pericanalicular actin web were incomplete. After cytochalasin D treatment, cultured hepatocytes were round but the surface were irregular with surfacen blebs, folds and grooves. Microvilli on the surface were scarce. Bile canaliculi were markedly dilated often with the detached junctional complexes. Bile canaliculi lacks microvilli almost completely and extended into the pericanalirular cytoplasm showing complex vacuolar and tubular structures by transmission electron mciroscopy. Pericanalicular actin web, intermediate filaments were hardly identified. Subsurface actin filaments were scattered scarcely under the cell membranes. These results suggest that hepatocytes isolated from rats can survive and form bile canaliculi in culture and the actin filaments are involved in the formation and/or maintenance of the bile canaliculi.

  • PDF

Ultrastructures of Zinc-containing Mast Cells Found in the Rat Hindpaw after an Inflammatory Stimuli: Zinc Selenium Autometallography (랫드 발바닥 염증부위에서 관찰된 zinc함유 비만세포의 미세구조: 조직화학적 염색을 중심으로)

  • Lee, Bo-Ye;Kim, Yi-Suk;Lee, Boeb-Y.;Lee, Hyun-Sook;Tak, Gye-Rae;Lee, Young-Il;Lee, Jeoug-Yeol;Jo, Seung-Mook
    • Applied Microscopy
    • /
    • v.36 no.4
    • /
    • pp.271-277
    • /
    • 2006
  • Mast cells (MCs) are granulated cells that play a pivotal role in allergic reaction and inflammation. The granules of mast cells are known to be rich in zinc (Zn). Male Sprague-Dawley rats were used. We injected $200{\mu}L$ of complete Freund's adjuvant (CFA) subcutaneously in the dorsal aspect of one hindpaw Finally, zinc selenium autometallography(AMG) was done by Danscher's method. The present study showed the ultrastructures of zinc-containing mast cells found in inflammatory area following an complete freund's adjuvant (CFA) inoculation into the rat hindpaw. At light microscopic level, mast cells were round or oval, at average $12{\mu}m$ in diameter, with many filopodia extending from the cell surface. Because the rather small and spherical nucleus was centrally placed; it was frequently obscured by the cytoplasmic granules, it sometimes could not be seen. Mast cells were distributed chiefly in the vicinity of small blood vessels. In most preparation many mast cells were ruptured and their granules escaped into the surrounding tissue. In electron micrographs, The secretory granules were at average $0.5{\mu}m$ in diameter and were limited by a membrane. The cell surface contained numerous microvilli and folds. Their interior was heterogenous in appearance. The nucleus was surrounded by large numbers of prominent vesicels and a well developed Golgi apparatus, but scant endoplasmic reticulum.

Effect of Rhois Galla extract on pancreatic glucokinase and hexokinase activities of interleukin-1β-induced diabetes mellitus mice (Cytokine interleukin-1β로 유발(誘發)된 당뇨병(糖尿病) 마우스의 췌장(膵臟) glucokinase 및 hexokinase 활성(活性)에 대(對)한 오배자(五倍子)의 효과(效果)에 관(關)한 연구(硏究))

  • Choi, Hyung-Il;Jeong, Ji-Cheon;Kim, Cheorl-Ho
    • The Journal of Dong Guk Oriental Medicine
    • /
    • v.7 no.1
    • /
    • pp.65-74
    • /
    • 1998
  • We investigated the in vivo effect of an aquous extract from Rhois Galla (R-G) on glucokinase and hexokinase activities of diabetes mellitus induced by interleukin-$1{\beta}$ ($IL-1{\beta}$). After 1 week of alloxan injection, the levels of serum glucose and insulin secretion were dramatically increased, however, the insulin secretion was decreased with administration of R-G. $IL-1{\beta}$ injection allowed the serum glucose level increased and the level was decreased by R-G administration. Furthermore, we could observe that R-G was effective in recovering the levels of insulin secretion. Enzyme activities of the glucokinase and hexokinase were decreased by $IL-1{\beta}$ treatment In contrast, R-G administration to the mice allowed proportion increasing. Seemingly, when $IL-1{\beta}$ was injected to the mice, enzyme activities of the glucokinase and hexokinase were decreased. But, R-G stimulated induction of enzyme activities of the glucokinase and hexokinase as high as normal group. These results suggested that R-G is highly effective in treatment of diabetes mellitus.

  • PDF

Influence of Copper Azole Retention Level to Wood Decay (목재 내 Copper Azole 보유량이 목재부후에 미치는 영향)

  • Lee, Hyun-Mi;Son, Dong-Won;Lee, Han-Sol;Hwang, Won-Joung
    • Journal of the Korean Wood Science and Technology
    • /
    • v.43 no.1
    • /
    • pp.112-121
    • /
    • 2015
  • In this study, Copper Azole (CuAz), a domestically available wood preservative for pressure treatment, was employed to perform an experimental research on its infiltration and decay properties in Japanese Red Pine. Test specimens were pressure-injected with CuAz-2 preservative to measure its preservative effectiveness, and then its impact on weight and mass losses. Furthermore, wood specimens were treated with CuAz-2 preservatives of various concentration levels before they were decayed with brown-rot-fungi in order to observe decay properties on light microscope (LM) and field emission scanning electron microscope (FE-SEM). As a result, untreated specimen by Fomitopsis palustris showed the mass loss of more than 40%, and the value of preservative effectiveness of CuAz-2 by indoor decay was $1,73-3.32kg/m^3$. The concentration levels of CuAz-2 preservative were shown to cause significant variations in terms of decay progresses in the cross section, radial section, and tangential section. By contrast, untreated specimens had underwent serious decays in early wood, late wood, longitudinal resin canals, and ray, which led to vertical destruction of wood texture. As for the radial section, ray tracheid, ray parenchyma cell, and window like pits were decayed and destroyed. In the case of tangential section, uniseriate rays and vertical resin canals were seriously decayed. In conclusion, this study indicates that the adequacy of the current CuAz injection amount should be reviewed in the domestic environment because there are significantly different decays at different decay conditions.

A STUDY ON THE FRACTURE RESISTANCE AND CHARACTERISTICS OF TEETH IN CLASS II CAVITY RESTORATIONS (2급(級) 와동(窩洞) 수복시(修復時) 치아파괴(齒牙破壞) 저항성(抵抗性) 및 귀열양상(龜裂樣相)에 관(關)한 연구(硏究))

  • Joo, Ik-Nam;Park, Sang-Jin;Min, Byung-Soon;Choi, Ho-Young
    • Restorative Dentistry and Endodontics
    • /
    • v.13 no.2
    • /
    • pp.337-348
    • /
    • 1988
  • The purpose of this study was to examine the fracture strength and characteristics of teeth with MOD cavity preparation. Freshly extracted sound maxillary premolars were cleaned and stored in normal saline solution $37^{\circ}C$ for 72 hours before experiments. The roots of teeth were embedded in a self-curing resin, and the exposed crown were maintained in a vertical position by a modelling wax in a brass ring. The MOD cavities were prepared with No. 57 carbide bur under high speed to a depth of 2.0mm and a width of 2.0mm(Fig.1). All the prepared teeth specimens were divided into 7 groups according to the mode of cavity form and restorative materials (Table 1, 2): Group I, unpreapred, intact teeth as control Group II, prepared cavity without restoration Group III, prepared teeth restored with amalgam Group IV, prepared teeth restored with composite resin (P-10) Group V, prepared teeth with beveled enamel margins restored with composite resin (P-10) Group VI, prepared teeth restored with light-cured composite resin (P-30) Group VII, prepard teeth with beveled enamel margins restored with light-cured composite resin (P-30) After placement of restorations, all of the specimens were stored in water at $37^{\circ}C$ for 72 hours before testing. All of the specimens were tested on the Instron Universal Testing machine (No. 6025) in order to evaluate the strength of fracture. One metal ball 5.0mm in diameter contacting the specimens parallel to the occlusal surface was used to in this study (Fig. 1). The fracture characteristics of the specimens were examined with naked eye and in the scanning electron microscope (JSM-20). The results obtained from this study were as follows: 1. The mean fracture strength was the highest in group VI and that in group II was the lowest. 2. The progress of crack of teeth propagated into the pulp cavity. 3. In case of the group of the restored teeth, the crack occurred to be accompanied with cuspal fracture. 4. The crack of restored teeth was initiated along the pulpo-axial line angle of the cavity.

  • PDF

Studies on Some Physico-Chemical Properties of the Acorn Starch (도토리전분(澱粉)의 이화학적(理化學的) 성질(性質)에 관(關)한 연구(硏究))

  • Kim, Jung-Ok;Lee, Mahn-Jung
    • Korean Journal of Food Science and Technology
    • /
    • v.8 no.4
    • /
    • pp.230-235
    • /
    • 1976
  • The current experiment has been carried out in order to find the chemical and physical properties of three species of the acorn starch. The results of the experiment are as follows. 1. Acorn is made up of 3.5-5.0% of lipid, 7.2-7.7% of protein, 71.6-76.3% of carbohydrate, and 1.9-2.2% of ash. 2. The purifying method of ether treated is better than that of 85% methanol treated for isolating pure starch. 3. Initial gelatinization temperature of the acorn starches ranged from $61-68^{\circ}C$; Quercus crispula Blume was the lowest and Quercus mongolica Fischer was the highest. On viscosity, Quercus mongolica Fischer shows the highest and Quercus crispula Blume shows the lowest. 4. It is estimated that the acorn starch lie halfway between those of the potato starch and the corn starch. By drying at $100^{\circ}C$, the crystal structure is destroyed first in the farther part of the lattice distance.

  • PDF