• Title/Summary/Keyword: 관상동맥혈관

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Depression and Coronary Artery Disease(I) : Pathophysiologic Mechanisms (우울증과 관상동맥 질환(I) : 병태생리적 기전)

  • Bae, Kyung-Yeol;Kim, Jae-Min;Yoon, Jin-Sang
    • Korean Journal of Biological Psychiatry
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    • v.15 no.4
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    • pp.275-287
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    • 2008
  • Depression and coronary artery disease are both highly prevalent diseases. Many previous studies suggest that depression is a common comorbid condition in patients with coronary artery disease and has a significant negative impact on the onset, course, and prognosis of coronary artery disease. However, the exact mechanisms that underlie the association between these two diseases remain unclear. Pathophysiologic mechanisms that may explain the effect of depression on coronary artery disease include hypercoagulability, hypothalamus-pituitary-adrenal axis and autonomic nervous system dysregulation, altered inflammatory response. On the contrary, pathophysiologic mechanisms in coronary artery disease that affect depression are less well known. It is also suggested that both diseases may share a common genetic vulnerability. The authors reviewed the literature on the pathophysiologic relationships of depression and coronary heart disease.

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Congenital Coronary Artery to Left Ventricular Fistula - A case report- (우관상동맥에서 좌심실로 유출되는 선천성 관상동맥루 -치험 1예-)

  • Kim Jin Sun;Yang Ji-Hyuk;Kim] Sung-Hye;Lee Heung Jae;Jun Tae-Gook
    • Journal of Chest Surgery
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    • v.38 no.7 s.252
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    • pp.501-503
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    • 2005
  • Coronary artery fistula accounts for $0.27\~0.4\%$ of all congenital cardiac defects. In more than $50\%$ of the cases, right coronary artery is involved. The fistula drains into the right heart in $92\%$ of the cases. Left heart is the site of termination in only $8\%$ of the cases, especially less left ventricle $(3\%)$. We experienced a case of right coronary artery to left ventricular fistula in a 3-year-old boy who was diagnosed incidentally and underwent ligation of fistula.

Severe Tricuspid Insufficiency after Correction of Anomalous Origin of the Left Coronary Artery from the Pulmonary Artery(ALCAPA) (ALCAPA 교정후 발생한 심한 삼첨판 폐쇄부전)

  • 백만종;김웅한;오삼세;류재욱;공준혁
    • Journal of Chest Surgery
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    • v.34 no.9
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    • pp.724-728
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    • 2001
  • We report a case of an 8 years and 11 month-old male patient who had developed severe tricuspid insufficiency(TI) after correction of anomalous origin of the left coronary artery from the pulmonary artery(ALCAPA). Transthoracic echocardiogram and coronary angiography confirmed ALCAPA, ischemic mitral regurgitation and trivial TI. He underwent direct reimplantation of the left coronary artery to the aortic root by using additional cannulation at the main pulmonary artery for arterial inflow and cardioplegia delivery to the left coronary artery. After the correction of ALCAPA, transesophageal echocardiogram(TEE) revealed good antegrade flow at the aortic implantation site of the left coronary artery and severe TI(Gr III-IV/IV). Cardiopulmonary bypass was reestablished and tricuspid valve was repaired with Kay-type annuloplasty, artificial chordae formation and chordal shortening plasty. The postrepair TEE revealed trivial to mild TI.

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Computer Analysis of Kinematic Parameters of the Intact Heart Using X-ray Image Sequence (X-ray 영상을 이용한 심장운동해석에 관한 연구)

  • Min, Byeong-Gu;Kim, Seong-Wan;Kim, Hui-Chan
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.22 no.4
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    • pp.101-112
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    • 1985
  • It is important to extract the mechanical informations from the image sequences of the moving object. We have studied the computer algorithms for analysis of the moving heart using X-ray image sequence. A new mathematical method was developed to estimate the local epicardial deformation, wall thickness, and the regional circumferential and longitudinal wall stress using biplane coronary cineangiograms. In this method, the motion images of the coronary artery bifurca-tion points were used as natural landmarks for the kinematic analysis of the ventricular deformation. In four dogs and a normal patient's coronary cineangiograms, the estimation results show the validity of the present analysis, compared with the experimental results based upon the implanted markers. Thus, the present method provides a new method of evaluating the regional wall deformation and wall stress together with the blood vessel conditions using the coronary cineangiography procedure.

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Correlation Between Atherosclerosis and Geometrical Characteristic Changes of Blood Vessels (혈관의 형태학적 특성변화와 동맥경화와의 상관관계)

  • Suh, Sang-Ho;Roh, Hyung-Woon;Kwon, Hyuck-Moon;Lee, Byoung-Kwon;Kim, Gye-Young;Lee, Na-Young
    • 순환기질환의공학회:학술대회논문집
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    • 2005.12a
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    • pp.23-24
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    • 2005
  • 위와 같은 결과로부터 개인마다 다르게 형성되는 혈관의 형상이 혈류역학적 특성을 변화시켜 동맥경화의 발생에 영향을 미치고 있음을 알 수 있었다. 즉, 동일한 관상동맥일지라도 기하학적 형태변화에 따라 좌주간지의 길이가 짧을수록, 좌전하행지와 좌회선지의 분지부 각도가 넓을수록, 동맥경화의 발생이 용이한 형태가 되는데, 이로 미루어 혈관의 형상이 혈류의 유동조건을 변화시켜 혈관내피세포의 손상, 혈류의 정체시간 연장 등으로 나타나 동맥경화가 발생되는 인자가 된다.

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