• Journal of the Korean association of regional geographers
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• v.15 no.3
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• pp.351-368
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• 2009

The internal structure of gateway city is to be influenced by the external relations. The purpose of this study is to examine the transportation impacts on the spatial characteristics of gateway cities in the Geum River basin, Korea. The changes of the transportation is classified by the commodity, the rice flow, and the functions of the gateway are examined in Gunsan-Si and Ganggyeong-Eup. Major findings of the study are as follows. First, the water and land transports in the gateways are connected or not. In the flow of the rice, the Gunsan gateway is connected, while the Ganggyeong is not. The difference is reflected in the location of the port and railway station. In the flow of marine products and salt, the Ganggyeong gateway is connected, while the Gunsan is not. Second, there had been separated or not in the location of the ports of the marine products and the rice. They are separated in the Gunsan, while not separated in the Ganggyeong. The results imply that there are to be difference between the two ports after the gateway of rice.

• Journal of Life Science
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• v.30 no.2
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• pp.169-177
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• 2020

For this study, we prepared organic solvent fractions from methanol extracts of Houttuynia cordata and Lespedeza cuneate, and analyzed their chemical components and various biological functions such as anti-oxidation, angiotensin-converting enzyme (ACE) inhibition, and α-glucosidase inhibitory activities. We found that DPPH radical scavenging activity was highest in the ethyl acetate fractions of Houttuynia cordata (90.8%) and Lespedeza cuneata (91.2%), whereas ABTS radical scavenging activity was highest in the ethyl acetate fractions of Houttuynia cordata (86.1%) and the chloroform fractions of Lespedeza cuneata (95.6%). FRAP activity was highest in the ethyl acetate fraction of Houttuynia cordata (360.1 mg TE/g) and Lespedeza cuneata (239.2 mg TE/g). ACE inhibitory activity was highest in the chloroform fraction of Houttuynia cordata (13.2%) and Lespedeza cuneata (35.2%). And, α-glucosidase inhibitory activity was highest in the ethyl acetate fraction of Houttuynia cordata (56.3%), and the water residue of Lespedeza cuneata (93.6%). Finally, we investigated the DPPH radical scavenging activity of 20 types of pure compounds identified in Houttuynia cordata and Lespedeza cuneate. The results show that quercetin demonstrates the highest DPPH radical scavenging activity. Overall, these results help us to understand the functional chemical components of Houttuynia cordata and Lespedeza cuneate and the biological effects of these components.

• Journal of the Korean association of regional geographers
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• v.18 no.1
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• pp.55-70
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• 2012

Busan port has played a part as the main trade gateway in Korea for several decades. However, due to the rapid integration of China into the global economy and the grand changes in global trade structures, the trade gateway system in Korea and the status of Busan port have been transformed. Busan port's role as a trade gateway toward Japan and U.S. has increased during last two decades but, in cases of China, its importance has relatively decreased. Moreover, Busan port's competitiveness has been undermined in the most part of commodity trade. These phenomena reflect the high competition among trade ports which tend to increase the effectiveness of supply chains. Based on the geographical research tradition which has understood a port as a nexus between hinterland and foreland, this study focuses the changes in characteristics of trade freights and the status as a gateway of Busan port. This approach will contribute to the understandings of dynamics in the comtemporary international logistics.

• Journal of the Korean Society of Food Science and Nutrition
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• v.41 no.11
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• pp.1540-1545
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• 2012

To investigate the inhibitory effects of Lespedeza cuneataextract (LC) on photo aging, skin aging was induced by UVB irradiation of hairless mice for 5 weeks. The skin erythema indices for the positive control (PC) and Lespedeza cuneata extract (LC-1%, 3%, and 5%) groups were lower than that of the control group. However, both lipid and water capacities of the PC and LC-3% groups were significantly higher than those of the control group. Skin wrinkles in the PC and LC-3% groups formed in a pattern of shallow furrows and thin crests. Skin TBARS contents and XO activity in the LC group were lower than those of the control group. The activities of GSH, SOD, and CAT in the LC-3% group were significant higher than those of the control group. Therefore, Lespedeza cuneata extract could be an effective natural herbal material for the inhibition of skin aging in hairless mice skin.

• Journal of the Korean Society of Food Science and Nutrition
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• v.45 no.6
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• pp.911-917
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• 2016

Lespedeza cuneata G. Don is an edible perennial herb used in traditional Korean medicine. We investigated the anti-proliferative properties and mechanism of L. cuneata extract. The ethanolic extract of L. cuneata dose-and time-dependently inhibited human colorectal cancer cell proliferation. A 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) assay was used to test the effect of the extract on proliferation of HT-29 colorectal cancer cells. The extract inhibited HT-29 cell proliferation with an $IC_{50}$ value of $554.26{\pm}8.81{\mu}g/mL$. L. cuneata extract suppressed production of pro-inflammatory cytokines interleukin-6 and tumor necrosis $factor-{\alpha}$. Apoptosis was evaluated by analysis of DNA fragmentation, poly(ADP-ribose) polymerase cleavage, caspase-3 activity, and protein expression of pro-apoptotic (Bax) and anti-apoptotic (Bcl-2). Our results demonstrated that the extract induced DNA fragmentation and characteristic morphological changes associated with apoptosis in HT-29 colorectal cancer cells. The extract also time- and dose-dependently up-regulated expression of the Bax and down-regulated expression of the Bcl-2. Furthermore, the extract dose- and time-dependently enhanced caspase-3 activity. Our findings provide evidence that L. cuneata extract may mediate its anti-proliferative effect via modulation of apoptosis.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.41 no.2
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• pp.173-180
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• 2021

Recently, the importance of competitive cities has emerged, and many cities around the world are striving to gain competitiveness. Domestic cities are also enhancing their competitiveness by taking advantage of the city's uniqueness and locality with strategies differentiated from other cities, and interest in city brands is increasing. This study seeks to enhance the city brand by improving the landscape elements of the airport, a representative international entrance. Through Instagram's hashtag function, it aims to derive elements of landscape preferred by airport users and to find ways to enhance Busan's city brand based on them.

• Proceedings of the Korean Society of Coastal and Ocean Engineers Conference
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• 1997.10a
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• pp.16-18
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• 1997

아산항은 초기에는 인천항의 보조항으로써 수도권 공단을 지원하는 공업항으로 개발하고, 최종적으로는 수도권의 제 2 관문항으로써, 서해 중부를 대상으로 중추 항만의 기능을 가질 수 있도록 개발 방향이 설정되어 있다. 아산항 배후의 세력권은 아산만으로부터 반경 30 - 40km 내 지역인 경기 남부의 충남ㆍ북부 일부와 수도권이 포함되어 있다. (중략)

• 대한생식의학회:학술대회논문집
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• 1997.11a
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• pp.73.1-73.1
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• 1997

• RED RIBBON
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• s.70
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• pp.6-7
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• 2006

구강은 신체의 관문과도 같은 기관으로 구강 안은 신체 다른 부위의 상태를 알려줄 수 있는 좋은 거울과도 같다. 에이즈 환자도 마찬가지이다. 에이즈는 면역체계의 기능을 약화시키는 질환으로 에이즈 환자에게서는 건강한 사람에게선 보기 힘든 질병들이 나타나기도 하고 일반인에게 나타나는 질병은 더 심하게 증상이 나타나기도 한다. 구강에서 나타나는 이러한 징후들은 HIV에서 AIDS로 진행되는 증후군으로 진단에 활용되기도 한다.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2020.11a
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• pp.11-14
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• 2020

대한민국 제1위 수출입 관문항인 여수·광양항의 코로나19 대응을 통한 항만기능 유지를 위해 수행중인, 육·해상(승선검역, 항만작업장, 입항선박, 항만초소 등 점검)검역 및 방역체계 사례.