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http://dx.doi.org/10.3746/jkfn.2012.41.11.1540

Inhibitory Effects of Lespedeza cuneata Ethanol Extract on Ultraviolet-Induced Photo Aging  

Kim, Hye-Jeong (Dept. of Biomedical Laboratory Science, Kyungwoon University)
Kim, Kil-Soo (College of Veterinary Medicine, Kyungpook National University)
Kim, Dae-Ik (Oriental Medicine Industry Support Center, Daegu Technopark)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.41, no.11, 2012 , pp. 1540-1545 More about this Journal
Abstract
To investigate the inhibitory effects of Lespedeza cuneataextract (LC) on photo aging, skin aging was induced by UVB irradiation of hairless mice for 5 weeks. The skin erythema indices for the positive control (PC) and Lespedeza cuneata extract (LC-1%, 3%, and 5%) groups were lower than that of the control group. However, both lipid and water capacities of the PC and LC-3% groups were significantly higher than those of the control group. Skin wrinkles in the PC and LC-3% groups formed in a pattern of shallow furrows and thin crests. Skin TBARS contents and XO activity in the LC group were lower than those of the control group. The activities of GSH, SOD, and CAT in the LC-3% group were significant higher than those of the control group. Therefore, Lespedeza cuneata extract could be an effective natural herbal material for the inhibition of skin aging in hairless mice skin.
Keywords
Lespedeza cuneata; skin aging; antioxidant activity; hairless mouse;
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Times Cited By KSCI : 6  (Citation Analysis)
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