• 제목/요약/키워드: 과도 변형

Search Result 2,573, Processing Time 0.029 seconds

Effects of Early Life Stress on the Development of Depression and Epigenetic Mechanisms of p11 Gene (생애 초기 유해 경험이 우울증의 발병과 p11 유전자의 후성유전기전에 미치는 영향)

  • Seo, Mi Kyoung;Choi, Ah Jeong;Lee, Jung Goo;Urm, Sang-Hwa;Park, Sung Woo;Seog, Dae-Hyun
    • Journal of Life Science
    • /
    • v.29 no.9
    • /
    • pp.1002-1009
    • /
    • 2019
  • Early life stress (ELS) increases the risk of depression. ELS may be involved in the susceptibility to subsequent stress exposure during adulthood. We investigated whether epigenetic mechanisms of p11 promoter affect the vulnerability to chronic unpredictable stress (CUS) induced by the maternal separation (MS). Mice pups were separated from their dams (3 hr/day from P1-P21). When the pups reached adulthood, we applied CUS (daily for 3 weeks). The levels of hippocampal p11 expression were analyzed by quantitative real-time PCR. The levels of acetylated and methylated histone H3 at p11 promoter were measured by chromatin immunoprecipitation. Depression-like behavior was measured by the forced swimming test (FST). The MS and CUS group exhibited significant decreases in p11 mRNA level and the MS plus CUS group had a greater reduction in this level than the CUS group. The MS plus CUS group also resulted in greater reduction in H3 acetylation than the CUS group. This reduction was associated with an upregulation of histone deacetylase 5. Additionally, the MS plus CUS group showed a greater decrease in H3K4met3 level and a greater increase in H3K27 met3 level than the CUS group. Consistent with the reduction of p11 expression, the MS plus CUS group displayed longer immobility times in the FST compared to the control group. Mice exposed to MS followed by CUS had much greater epigenetic alterations in the hippocampus compared to adult mice that only experienced CUS. ELS can exacerbate the effect of stress exposure during adulthood through histone modification of p11 gene.

Pseudotachylyte Developed in Granitic Gneiss around the Bulil Waterfall in the Jirisan, SE Korea: Its Occurrence and Characteristics (지리산 불일폭포 일원의 화강암질편마암에 발달한 슈도타킬라이트: 산상과 특성)

  • Kang, Hee-Cheol;Kim, Chang-Min;Han, Raehee;Ryoo, Chung-Ryul;Son, Moon;Lee, Sang-Won
    • The Journal of the Petrological Society of Korea
    • /
    • v.28 no.3
    • /
    • pp.157-169
    • /
    • 2019
  • Pseudotachylytes, produced by frictional heating during seismic slip, provide information that is critical to understanding the physics of earthquakes. We report the results of occurrence, structural characteristics, scanning electron microscopic observation and geochemical analysis of pseudotachylytes, which is presumed to have formed after the Late Cretaceous in outcrops of the Paleoproterozoic granitic gneiss on the Bulil waterfall of the Jirisan area, Yeongnam massif, Korea. Fault rocks, which are the products of brittle deformation under the same shear stress regime in the study area, are classified as pseudotachylyte and foliated cataclasite. The occurrences of pseudotachylyte identified on the basis of thickness and morphology are fault vein-type and injection vein-type pseudotachylyte. A number of fault vein-type pseudotachylytes occur as thin (as thick as 2 cm) layers generated on the fault plane, and are cutting general foliation and sheared foliation developed in granitic gneiss. Smaller injection vein-type pseudotachylytes are found along the fault vein-type pseudotachylytes, and appear in a variety of shapes based on field occurrence and vein geometry. At a first glance fault vein-type seudotachylyte looks like a mafic vein, but it has a chemical composition almost identical to the wall rock of granitic gneiss. Also, it has many subrounded clasts which consist predominantly of quartz, feldspar, biotite and secondary minerals including clay minerals, calcite and glassy materials. Embayed clasts, phenocryst with reaction rim, oxide droplets, amygdules, and flow structures are also observed. All of these evidences indicate the pseudotachylyte formed due to frictional melting of the wall rock minerals during fault slip related to strong seismic faulting events in the shallow depth of low temperature-low pressure. Further studies will be conducted to determine the age and mechanical aspect of the pseudotachylyte formation.

Automatic Fracture Detection in CT Scan Images of Rocks Using Modified Faster R-CNN Deep-Learning Algorithm with Rotated Bounding Box (회전 경계박스 기능의 변형 FASTER R-CNN 딥러닝 알고리즘을 이용한 암석 CT 영상 내 자동 균열 탐지)

  • Pham, Chuyen;Zhuang, Li;Yeom, Sun;Shin, Hyu-Soung
    • Tunnel and Underground Space
    • /
    • v.31 no.5
    • /
    • pp.374-384
    • /
    • 2021
  • In this study, we propose a new approach for automatic fracture detection in CT scan images of rock specimens. This approach is built on top of two-stage object detection deep learning algorithm called Faster R-CNN with a major modification of using rotated bounding box. The use of rotated bounding box plays a key role in the future work to overcome several inherent difficulties of fracture segmentation relating to the heterogeneity of uninterested background (i.e., minerals) and the variation in size and shape of fracture. Comparing to the commonly used bounding box (i.e., axis-align bounding box), rotated bounding box shows a greater adaptability to fit with the elongated shape of fracture, such that minimizing the ratio of background within the bounding box. Besides, an additional benefit of rotated bounding box is that it can provide relative information on the orientation and length of fracture without the further segmentation and measurement step. To validate the applicability of the proposed approach, we train and test our approach with a number of CT image sets of fractured granite specimens with highly heterogeneous background and other rocks such as sandstone and shale. The result demonstrates that our approach can lead to the encouraging results on fracture detection with the mean average precision (mAP) up to 0.89 and also outperform the conventional approach in terms of background-to-object ratio within the bounding box.

A study on Contemporary Transmission Aspect of Traditional Danjong Story - With a focus on the Lee Gab Soon Yeonhaengbon (단종 설화의 현대적 전승 양상 연구 - 이갑순 씨 연행본을 중심으로 -)

An adaptive digital watermark using the spatial masking (공간 마스킹을 이용한 적응적 디지털 워터 마크)

  • 김현태
    • Journal of the Korea Institute of Information Security & Cryptology
    • /
    • v.9 no.3
    • /
    • pp.39-52
    • /
    • 1999
  • In this paper we propose a new watermarking technique for copyright protection of images. The proposed technique is based on a spatial masking method with a spatial scale parameter. In general it becomes more robust against various attacks but with some degradations on the image quality as the amplitude of the watermark increases. On the other hand it becomes perceptually more invisible but more vulnerable to various attacks as the amplitude of the watermark decreases. Thus it is quite complex to decide the compromise between the robustness of watermark and its visibility. We note that watermarking using the spread spectrum is not robust enought. That is there may be some areas in the image that are tolerable to strong watermark signals. However large smooth areas may not be strong enough. Thus in order to enhance the invisibility of watermarked image for those areas the spatial masking characteristics of the HVS(Human Visual System) should be exploited. That is for texture regions the magnitude of the watermark can be large whereas for those smooth regions the magnitude of the watermark can be small. As a result the proposed watermarking algorithm is intend to satisfy both the robustness of watermark and the quality of the image. The experimental results show that the proposed algorithm is robust to image deformations(such as compression adding noise image scaling clipping and collusion attack).

Isolation and Physicochemical Properties of Rice Starch from Rice Flour using Protease (단백질분해효소에 의한 쌀가루로부터 쌀전분의 분리 및 물리화학적 특성)

  • Kim, ReeJae;Oh, Jiwon;Kim, Hyun-Seok
    • Food Engineering Progress
    • /
    • v.23 no.3
    • /
    • pp.193-199
    • /
    • 2019
  • This study aimed to investigate the impact of protease treatments on the yield of rice starch (RST) from frozen rice flours, and to compare the physicochemical properties of RST by alkaline steeping (control) and enzymatic isolation (E-RST) methods. Although the yield of E-RST, prepared according to conditions designed by the modified 23 complete factorial design, was lower than the control, the opposite trends were observed in its purity. E-RST (RST1, isolated for 8 h at 15℃ with 0.5% protease; RST2, isolated for 24 h at 15℃ with 1.5% protease; RST3, isolated for 24 h at 15℃ with 0.5% protease) with the yields above 50% were selected. Amylose contents did not significantly differ for the control and RST2. Relative to the control, solubilities were higher for all E-RST, but swelling power did not significantly differ for E-RST except for RST1. Although all E-RST revealed higher gelatinization temperatures than the control, the reversed trends were found in the gelatinization enthalpy. The pasting viscosities of all E-RST were lower than those of the control. Consequently, the enzymatic isolation method using protease would be a more time-saving and eco-friendly way of preparing RST than the alkaline steeping method, even though its characteristics are different.

A Study of the Material Properties of Steel Used to Repair the Stupa of State Preceptor Jigwang from Beopcheonsa Temple, Wonju in 1957 (1957년 원주 법천사지 지광국사탑 수리에 사용된 철물(鐵物)의 재료학적 특성 연구)

  • You, Harim;Lee, Jaesung;Lee, Taejong;Park, Heejeoung
    • Korean Journal of Heritage: History & Science
    • /
    • v.53 no.4
    • /
    • pp.100-117
    • /
    • 2020
  • National Treasure no. 101, the stupa of State Preceptor Jigwang from the Beopcheonsa Temple Site in Wonju has been transferred from place to place and reassembled several times since it was built. In particular, overall dismantling and repair was carried out in 1957 to restore parts damaged by bombing during the Korean War. Documented information on the repair process and materials used at that time does not exist. However, various types of metal materials used for this stupa have been identified during conservation work. Besides clamps anchor bolts, 9mm-thick circular rebars were mainly used for joining the parts of this stupa, while circular rebars and wires of various thicknesses were used for joining the parts with mortar restoration materials. Although deformed bars are typically used for stone pagodas classified as architectural structures, smooth circular rebars were used in this case. In terms of restoration using mortar, material shapes were transformed, bound alternately, and twisted irregularly to improve bonding strength and coherence in order to insert restoration materials and to bolster structural weaknesses. In addition, metallographic analysis showed the material to be hypo-eutectoid steel with low carbon content. Many non-metallic inclusions in the shape of drops of different sizes were included, which do not affect the whole elemental composition due to the very small quantities involved. Qualitative and EPMA analysis of Mn and S, which were not identified by SEM-EDS area analysis, established an even distribution of MnS in crystal grains of the microstructure, regardless of the shape of the samples. It is presumed that secondary homogenization and softening might have been conducted after manufacturing to facilitate the working process. Furthermore, in consideration of properties indicating that the thinner the steel is, the less carbon content contained and the greater the elasticity and elongation, it is judged that restoration work was ordered.

A Study on the Methods of Mounting the Five Peaks Screen - With the focus on green bordering silk and gilt ornamentation (궁중 의례용 일월오봉도 병풍의 장황에 관한 고찰 - 초록색 회장 비단과 금박 장식을 중심으로 -)

  • PARK, Yoonhee
    • Korean Journal of Heritage: History & Science
    • /
    • v.55 no.1
    • /
    • pp.243-263
    • /
    • 2022
  • The royal court of Joseon had a tradition of mounting the Irworobongdo, a painting of the sun, the moon and the five sacred peaks, symbols of the king's immortal presence and authority, on a folding screen and placing it in special spaces within the palace that were reserved for the king. While the Irworobongdo is generally accepted as the important ceremonial object of the royal palaces of Joseon, there have been few studies on the various folding screens used in the royal palaces, largely because the official records about such screens do not match the remaining original relics. In this study, the main discussion is focused on the diversity of the shapes and mounting materials of the Irworobongdoused for various ceremonies held in the royal palaces of Joseon based on the Uigwe, the official records of the royal protocols of the Joseon dynasty. The discussion also extends to the theme rarely studied so far, namely the original form of the Irworobongdo and its evolution in the following period. The ceremonial "five peak" folding screens (Obongbyeong) used at a number of important palace buildings, including the crown hall (Jeongjeon), royal funerary hall (Binjeon), spirit hall (Honjeon) and portrait shrine (Jinjeon), differed in shape and size from the folding screens used in royal celebratory events such as banquets, although the paintings themselves and the style of mounting them were essentially the same. The paintings were mounted on screens bordered with green silk and ornamented with floral gilt designs. The folding screens used in royal ceremonies were produced according to strict guidelines that required the ceremonies and mounting materials to be graded on the basis of the status of each screen. It was not until the 1960s that these ceremonial folding screens of the Joseon dynasty, which had been neglected during the period of Japanese colonial rule of Korea, began to undergo conservation treatment provided as part of a heritage preservation program. Unfortunately, many of the screens repaired in this period lost some of their original features - largely due to the use of non-traditional mounting techniques. Considering, however, that significant achievements have since been made in the heritage preservation field based on the use of historical evidence, it is now necessary to systematically use the repair history of the information about the remaining royal ceremonial folding screens to ensure that they are preserved and managed more effectively in the future.

Comparative Study of Actual Vegetation and Past Substitutional Vegetation to Baekje Historic Site in Seoul - Focusing on Pungnaptoseong(風納土城) and Mongchontoseong(夢村土城) - (서울 백제역사유적지 관리를 위한 현존식생과 과거 대상식생 비교 연구 - 풍납토성(風納土城)과 몽촌토성(夢村土城)을 중심으로 -)

  • Cha, Doo-Won;Oh, Choong-Hyeon
    • Journal of the Korean Institute of Traditional Landscape Architecture
    • /
    • v.40 no.1
    • /
    • pp.74-80
    • /
    • 2022
  • The vegetation of historical sites has been a form of vegetation that has remained since some years ago, but in modern times, vegetation and terrain have been deformed or damaged due to urban development, which was followed by an industrialization. As a solution to this, it is necessary to establish a plan for restoration and management by referring to the vegetation and landscape remaining in the historic site as indicators. This study was conducted to provide basic data for vegetation and landscape management of Baekje Historic Sites in Seoul by comparing and analyzing location characteristics, existing vegetation, and remaining vegetation of past substitutional vegetation for Pungnaptoseong and Mongchontoseong, Baekje Historic Sites in Seoul. As a result of the study, Pungnaptoseong and Mongchontoseong are located near the main stream of the Han River, Pungnaptoseong is located on a flat land consisting of natural embankments and floodplains, and Mongchontoseong is located on a hilly area. In the case of existing vegetation, it has been confirmed that Pungnaptoseong mainly has ornamental trees planting sites, while Mongchontoseong has a distribution of residual species from the past that grow in villages and hilly lowlands. The Substitutional vegetation of Pungnaptoseong and Mongchontoseong was synthesized based on the location characteristics and actual vegetation, it is estimated that the hilly areas may have been divided into "Quercus aliena Blume.", "Quercus mongolica Fisch. ex Ledeb." and so on, "Pinus densiflora Siebold & Zucc." on dry land,"Salix koreensis Andersson.", "Juglans mandshurica Maxim.", "Alnus japonica (Thunb.) Steud." in rivers and tributaries, "Quercus acutissima Carruth." in the main part of the forest, "Pinus densiflora Siebold & Zucc.", "Salix koreensis Andersson.", "Zelkova serrata (Thunb.) Makino." as a divine tree in the beginning of the village. Since the 1960s, all substitutional vegetation in the past has disappeared due to the introduction of foreign species and the creation of urban areas in Pungnaptoseong and Mongchontoseong, and the landscape has also been damaged. Fortunately, the substitutional vegetation was estimated in consideration of the species of residual trees distributed along the walls, climate, location characteristics, and times, but this study was conducted based on literature and existing vegetation surveys. Therefore, it is necessary to supplement the past target vegetation in Baekje historical sites in Seoul through quantitative experiments such as plant relic analysis in the future.

Study on Film Music for and (영화 <메리 포핀스>와 <메리 포핀스 리턴즈> 영화음악 분석 연구)

  • Hwang, Jin-Hee
    • Journal of Korea Entertainment Industry Association
    • /
    • v.15 no.5
    • /
    • pp.55-68
    • /
    • 2021
  • The purpose of this study is to analyze the characters and narratives of series films and to extract corresponding elements of film music to compare and analyze how musical elements were utilized. The scope of the study was analyzing the story structure and characters of the films "Mary Poppins" and "Mary Poppins Returns" and the corresponding film music. After comparing the contents of the film "Mary Poppins" and "Mary Poppins Returns," the film matched the film music equivalent to the similar scenes of the two films. As a result, seven of the 11 songs of "Mary Poppins" overlap with those used in similar narratives of "Mary Poppins Returns", and eight songs overlap in "Mary Poppins Returns". Seven songs from "Mary Poppins" and eight songs from "Mary Poppins Returns" can be divided into nine scenes in total when connected to a common narrative. Among them, "A Spoonful of Sugar" from "Mary Poppins", "Jolly Holiday", "A cover is not the Book" from "Mary Poppins Returns" and "Triple light fantastic" were overlapping songs with narratives. Based on this, it analyzes leitmotiv film music, focusing on characters from the films "Mary Poppins" and "Mary Poppins Returns." The common leitmotivs in the two films are Mary Poppins leitmotiv, Lesson leitmotiv, Lullaby leitmotiv, World leitmotiv, Chimney Sweeper leitmotiv, Up & Down leitmotiv, Chimney Sweeper leitmotiv, and Sky leitmotiv. The characteristic rhythm and pitch used in Mary Poppins leitmotivs were used in the overall song featuring Mary Poppins. Through this, the elements of music symbolizing Mary Poppins, a key figure, were matched to the films "Mary Poppins" and "Mary Poppins Returns" and modified according to the narrative flow. The analysis results of this work have theoretical significance in that it is necessary to analyze the narratives and film music of series films to discover common features and consider how they are matched in theoretical terms.