• Herbal Formula Science
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• v.22 no.1
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• pp.105-112
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• 2014

Background and objective: Methamphetamine (Meth) is a widely abused psychostimulant that produces hyperlocomotion in rodents. Radix of Glycyrrhizae uralensis comprises a variety of bioactive components that have neuroprotective effects. In a previous study, we have demonstrated methanol extracts from radix of Glycyrrhizae uralensis (MEGR) suppress acute cocaine-induced extracellular dopamine release in the nucleus accumbens. In the present study, we investigated the effect of MEGR on acute Meth-induced hyperlocomotion. Methods: Male Sprague-Dawley rats were orally administered with MEGR (60 mg/kg and 180 mg/kg) 60 min prior to an intraperitoneal injection of Meth (1.0 mg/kg). Results: Behavioral analysis showed acute Meth greatly increased locomotor activities, while pretreatment with MEGR dose dependently inhibited the hyperlocomotion. In parallel, there were markedly increased levels of dopamine and its metabolite 3, 4-dihydroxyphenylacetic acid in the nucleus accumbens tissues in Meth-treated rats, which were also almost completely reversed by 180 mg/kg MEGR. Conclusions: These results showed that radix of Glycyrrhizae uralensis attenuates Meth-induced hyperlocomotion by inhibiting dopamine synthesis and utilization, suggesting that radix of Glycyrrhizae uralensis might be effective in blocking the rewarding effect of Meth.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.2 no.1
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• pp.150-154
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• 1991

1012 Yunbyun children (500 of chinese and 512 of Korean ancestry) in kindergarten through sophomore in highschool were assessed using CBCL parental form and their data were compared to study differences in behavior problems among children of korean and chinese ancestry in Yunbyun. The results indicated that social withdrawal, depressive, somatic complaints and aggressive syndromes were fairey common among Yunbyun children of both korean and chinese ancestry and that compared to children in the u. s. and shanghai. Yunbyun children showed more social withdrawal but less aggressive behaviors. Internalizing syndromes such as uncommunicative, schizoid, obsessive and anxious syndromes were more prevalent among children of chinese ancestry, while hyperactive and aggressive syndromes were more prevalent among children of korean ancestry.

• KDI Journal of Economic Policy
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• v.18 no.2
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• pp.63-116
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• 1996

우리나라 제조업(製造業)의 수직적(垂直的) 구조(構造)는 선진공업국에 비하여 소(小) 영세기업(零細企業)의 비중이 월등히 높은 피라미드형의 형태를 보이며 80년대말 이후 소기업군의 확대는 더욱 두드러지고 있다. 이처럼 소기업의 비중이 높아진 것은 제조업체들이 가격경쟁력(價格競爭力)을 높이기 위하여 생산비용이 높게 드는 자체생산(自體生産)을 가능한 한 줄이고 임금(賃金)이 낮은 중소기업으로 생산공정을 이양해 왔기 때문이다. 소기업 비중이 높은 분업구조는 가격경쟁력이 중시되어 생산을 분업화해야 하는 경제체제에서는 높은 효율성(效率性)을 발휘한다고 평가할 수 있다. 90년대에 이르러 중소기업이 저가(低價)의 생산요소(生産要素)를 조달받기 어려운 경제여건이 조성되면서 중소기업의 경영불안이 높아지는 등 가격경쟁력을 유지하기 위한 생산분업체제(生産分業體制)는 한계(限界)에 도달한 것으로 보인다. 따라서 대기업과 중소기업간 분업도 기술(技術) 중심의 분업관계(分業關係)로 전환되어야 할 단계에 이르렀다고 볼 수 있다. 그러나 종전과 같이 소기업(小企業)에 의존하는 분업구조(分業構造)로는 기술분업(技術分業)이 정착되기 어렵다. 왜냐하면 연구개발, 전문인력의 고용 등 기술개발과 관련된 기업활동에는 생산량에 관계없이 고정비용(固定費用)이 들어서 기술개발 비용과 위험을 분산시키려면 기업의 생산규모가 상당히 커져야 하기 때문이다. 이는 소기업 중심의 분업구조가 중견기업(中堅企業)중심의 구조로 개편(改編)되어야 함을 의미한다. 중견기업이 육성되려면 첫째, 대기업과 직거래하는 중소업체(中小業體)의 수(數)가 축소되어야 한다. 거래업체수의 과다는 기업규모를 영세하게 만드는 가장 직접적 요인이기 때문이다. 그러나 거래업체의 정리과정에서 기존업체들이 중소기업 보호여론을 등에 업고 반발할 수 있고, 대기업이 교섭력을 강화하기 위한 수단으로 악용할 수 있으므로 객관적이고 투명한 정리기준의 제시가 전제되어야 한다. 둘째, 대기업의 중소기업에 대한 대폭적 자본참여(資本參與)가 허용되어야 한다. 대기업의 자본참여는 중소기업 지배를 강화할 것으로 우려되어 현재는 극히 부분적으로 허용하고 있으나, 개방경제하에서는 대기업과 국내 중소기업간의 협력관계를 유지시키는 효과적 수단으로 작용하게 될 것이다. 셋째, 은행 등 금융자본(金融資本)의 중견기업에 대한 투자(投資) 활성화(活性化)가 필요하다. 금융자율화로 금융기관의 수익성이 강조되는 상태에서 금융자본이 거래업체의 주주(株主)로서 참여하면 경영정보를 손쉽게 파악할 수 있어 우량업체의 신속한 육성이 가능해질 수 있다.

• Fire Science and Engineering
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• v.29 no.6
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• pp.71-75
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• 2015

Recently, Since buildings are bigger and higher, the damage of human life can be increased by fire flame and smoke in fire. Smoke control system is necessary to decrease this damage. Therefore, Air supply pressurization smoke control system is applied to vestibule of escape stairway. NFSC requires pressure differential of 40 Pa~60 Pa, but pressure differential is over 60 Pa in the field. It is known that the cause of this over pressure differential is much leakage of damper. Over pressure differential can bad effect to escaper by pressurizing the door. Analyze the real leakage of damper by testing for identifying this problems. The result of testing, leakage is $0.090m^3/s{\sim}0.154m^3/s$. It is necessary to limit the leakage of dampers for safe of escapers.

• Economic and Environmental Geology
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• v.50 no.4
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• pp.267-276
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• 2017

Seawater intrusion into coastal fractured rock aquifer, resulting in groundwater contamination, is of serious concern in coastal areas of Jeolla Namdo, Korea, which heavily depends on groundwater resources. Time series analysis and forecasting were carried out to analyze and predict EC which is a major indicator of seawater intrusion. Two time series models of autoregressive integrated moving average (ARIMA) and seasonal autoregressive integrated moving average (SARIMA) were tested for suggesting appropriate time series model. Time series data of EC measured over one year showed a increasing trend with short periodic fluctuations, due to tidal effect and pumping, which indicated that EC time series data tended to be non-stationary. SARIMA model was found better fitted to observed EC than any other time series model. Time series analysis and modeling was found to be a useful tool to analyze EC at coastal fractured rock aquifer subject to seawater intrusion.

• Journal of Digital Convergence
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• v.14 no.2
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• pp.501-507
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• 2016

We obtained medical test data of 150 male from National Health Insurance Corporation, that included physique, blood chemistry, and lifestyle. ${\chi}^2-test$ and logistic regression, and multiple regression were done to verify how CAD risks and/or lifestyle are different between obese and non-obese person. SPSS(version 18) was used for statistical procedures and p-value of .05 was regarded as good through. ${\chi}^2-test$ showed the frequency of hypertension, htperglycemia, hyperlipidemia were higher in obese person than in non-obese This result told us that lifestyle modification could be a key to prevent cardiovascular disease by controlling and managing body composition, especially abdominal obesity.

• Journal of Digital Contents Society
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• v.19 no.5
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• pp.845-852
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• 2018

This study has developed a preventive launcher from smartphone addiction for the digital generation and the contents recommendation based on machine learning which used multiple and collective intelligence. This could provide convenient digital nurturing experience for the parents who fear their children's over use of digital devices and also suggest individually adaptive digital learning methods that enhance the learning efficiency and pleasurable and safe learning environment for the children. Suggested application is a kind of gamification launcher that protects children from harmful contents and from smartphone addiction with time limit settings. For parents who find difficulty choosing from various kinds of contents and applications for education, this suggested system could provide a learning analytic report based on big data after collecting and analyzing the data of their children's learning and activities and recommend contents necessary for their kids using recommended algorithm by collective intelligence.

• The Journal of Information Systems
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• v.18 no.4
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• pp.19-40
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• 2009

승자독식(Winner Takes All)이라는 글로벌 경쟁원리로 인해 세계 주요 국가들 사이에 R&D 경쟁이 갈수록 치열해지고 있다. 이에 우리나라에서도 R&D 지원 확대 및 다양한 정책기획 활동 등이 전개되었다. 이러한 노력에도 불구하구 국가 차원에서 기획 및 정책조정이 효과적으로 추진되지 못하고 있으며, 국가연구개발사업 차원에서는 "기획의 양척 과다와 질적 부실"이라는 비판이 제기되고 있다. 반면에 기술 융복합화의 가속화 등 R&D 환경의 불확실성은 더욱 높아졌으며 국가연구개발사업의 규모 증가와 함께 연구기획의 복잡성은 더욱 더 높아졌다. 최근에는 국가 차원의 비전수립과 중장기 정책기획에 기초하여 사업기획과 과제기획을 연계 수행하는 등 기획을 통해 과제를 도출하는 하향식 접근이 강조되면서 기획의 중요성은 더욱 커졌다. 최근 연구기획의 새로운 기법으로서 정보분석 방법론(Information Analysis Method)이 대두되고 있다. 국가연구개발사업의 효율적 기획을 위하여 기존 기술기획 위원회(Peer Review) 방식 외에 정보분석 방법론을 통한 보완이 필요하다. 본고의 목적 크게 두 가지로 설명할 수 있다. 첫째, 현재 진행되고 있는 연구기획 및 연구기획 방법론으로 기장 많이 활용되고 있는 전문가 위원회의 한계를 제시하였다. 둘째, 최근 대두되고 있는 정보분석 방법론과 정보분석 시스템 구축, 그리고 이를 활용한 10대 기술(반도체, 디스플레이, 디지털 망원전파, 이동통신, BcN, 차세대 컴퓨팅, SW솔류션, 디지털콘텐츠, 임베디드 SW, 지식정보보안)에 대한 유망기술 발굴 실증분석을 실시하였다.

• Journal of the Korean GEO-environmental Society
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• v.8 no.4
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• pp.67-74
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• 2007

Many studies for slope stability studies have indicated that the infiltration of rainwater into a slope decrease the slope stability. In order to minimize damage caused by slope failure, most design codes suggest that the slope stability be analyzed by saturated condition during rainy season. However it would be excessively conservative condition that every soil slope is saturated in rainy season irrespective of rainfall intensity, soil type and slope geometry. In addition, because most soil slopes are in an unsaturated state, it is necessary to consider the unsaturated characteristics of slope. This paper suggests a prediction method of saturation time for the weathered granite soil slopes due to rainfalls. The finite element analysis of transient water flow through unsaturated slope was used to investigate effects of soil-water characteristics, permeability at saturation, slope geometry, and rainfall intensity. From the result of these analyses, the prediction charts considering soil-water characteristics, permeability at saturation, and slope height were proposed in this study. It is possible to the time required to be saturated slope after rainfall.

• Journal of Information Technology and Architecture
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• v.11 no.2
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• pp.143-155
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• 2014

In recent years, domestic electronics, banking, electricity, services, manufacturing, pharmaceutical, corporate type and malicious hackers is corporate security through the accident occurred and the resulting loss of corporate information and the damage each year is steadily increasing. Many companies have responded to domestic business activities and to protect critical information related to laptops, smart phones, tablets, and introduced a variety of Endpoint security solutions within. However, being introduced to senselessly Endpoint security solution across the over-budget, with the same features and performance, such as conflicts and problems arise, resulting in additional maintenance costs, in an effort to resolve the conflict in the operational security of the IT department's new difficulty in becoming. Here is the introduction and operation of these Endpoint security solutions in order to solve the problem on employees's PC into the center of the information security governance based on Endpoint security solution to provide the process for determining the solutions presented.