• Science of Emotion and Sensibility
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• v.16 no.3
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• pp.333-340
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• 2013

The purpose of this paper is to evaluate facade design factors of old dwellings using a Fuzzy Analytical Hierarchy Process (AHP) based on a pairwise comparison analysis using "Façade Design Factors" as evaluation criteria. Traditional old dwellings were presented and evaluated. A Fuzzy AHP based model was used for pairwise comparison of traditional old dwellings, whereby seven criteria and nine alternatives were described through a questionnaire and constructional data. The Fuzzy AHP was used to determine the impact of the facade design factors, because "Traditional" old dwellings are identified by the combination of their facade design factors. Furthermore, the fuzzy AHP is used to verify the feasibility and efficiency of this approach as well as for extent analysis to comprehend the priority of the traditional old dwellings using a sensibility measuring scale.

• Journal of the Korean Society for information Management
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• v.37 no.3
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• pp.51-75
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• 2020

All public libraries are collection-based knowledge and cultural service institutions. To this end, a collection development policy is an essential and a strategic menu that every library should establish first. Regional central libraries should establish and apply optimal collection development policies to conduct the legal duties as knowledge and information centers and cooperative preservation facilities of the cities and provinces. Thus, this study analyzed and compared in detail the collection development guidelines (draft) and regulations of regional central libraries in Korea and the collection development policies of metropolitan public libraries abroad. Results showed that the policies of domestic regional central libraries were simply practical guidelines while those in most developed countries were substantial in format and content. All regional central library systems should establish and document collection development policies based on the importance of collection development, future-oriented thinking, and strategic decision. The study also suggested the basic principles and the format for this purpose.

• KSBB Journal
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• v.17 no.4
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• pp.350-356
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• 2002

Low density polyethylene(LDPE) film was fabricated with the addition of benzoic acid, or/and JP which contained water-soluble silica adsorbed a natural antimicrobial compounds. The used antimicrobial compounds were isolated from culture broths of methylotropic actinomycetes strains MO-16 and MO-17 which was newly isolated from soils. An antimicrobial compound retained antimicrobial activity after heat treatment at 121$^{\circ}C$ for 5 min. JP, which obtained from Japan as a antimicrobial agent, showed antimicrobial activity in the concentration of 100 mg/mL. The silica LDPE film revealed the growth inhibition of total aerobic bacteria in packaged minced pork compared with commercial film and of E. coil on a contained agar plate. In the storage testing of various packaged foods at room temperature for 30 days, the film showed excellent preservation compared with commercial film in case of small tomato and Agaricus bisporus.

• Plant Journal
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• v.14 no.1
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• pp.34-41
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• 2018

Current study is the era of fusion, and future study is the era of integration. The prerequisite of study integration is that all studies must be equal to each other, and only laws derived from natural laws can achieve the equivalence of integration. We suggest that the ability to make change is defined as energy. All things change, the change necessarily has directionality, therefore change and directionality apply equally to all studies. The zeroth law of integral studies is the law of existence, the first law is the law of change conservation, the second law is the law of increasing non-available change, the third law is the law of the guidelines, and the fourth law is the law of fusion. The above laws are very similar to the law of thermodynamics. The ultimate aim of the five integral laws is the realization of a community in which natural, human, and AI individuals cooperate and develop each other on the earth.

• Korean Journal of Microbiology
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• v.53 no.1
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• pp.49-54
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• 2017

Sus1 / ENY2 is a tiny conserved protein that is involved in chromatin remodeling and mRNA biogenesis. Sus1 is associated to two nuclear complexes, the transcriptional coactivator SAGA and the nuclear pore associated TREX2. In fission yeast, Schizosaccharomyces pombe, ortholog of Sus1 / ENY2 was identified from the genome database. Tetrad analysis showed that the S. pombe sus1 is not essential for growth. However, deletion of the sus1 gene caused cold-sensitive growth retardation with slight accumulation of $poly(A)^+$ RNA in the nucleus. And the Sus1-GFP protein is localized mainly in the nucleus. Yeast two-hybrid analysis and co-immunoprecipitation experiment showed that Sus1 interacts with Sac3, another subunit of TREX2 complex. These results suggest that S. pombe Sus1 is also involved in mRNA export from the nucleus as a component of TREX-2 complex.

• Journal of the Society of Naval Architects of Korea
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• v.32 no.4
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• pp.38-47
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• 1995

The three-dimensional multi-layer computer simulation technology for tidal current developed in the previous study is updated to a new version. many improvements are achieved by following changes : (1) No-reflection condition is adopted instead of no-gradient condition as an open boundary condition. (2) Time marching algorithm is changed so that velocity and pressure(surface movement) might be salved in turn at different time step (3) Convection term in equation of motion is estimated by upwind differencing scheme instead of central differencing. The stability is improved considerably and the steady state is achieved within 2 tidal periods which is about 3 times shorter than that of the old version. Moreover, fluctuations in time disappeared by introducing the new time marching technique. An application to the real near shore area(near Inchon harbor) is performed by the new version. Simulated results are compared with those by the simulation total developed in the University of Tokyo. Validity and effectiveness of the two simulation technologies are chocked through the comparative research works.

• Korean Journal of Microbiology
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• v.54 no.4
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• pp.325-329
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• 2018

Thp1/PCID2, PCI domain-containing protein, is a component of the evolutionally conserved TREX-2 complex linking mRNA transcription and export. In fission yeast, Schizosaccharomyces pombe, the pci2 (SPBC1105.07c) gene encodes a PCI domain-containing protein that is predicted as a fission yeast orthologue of Thp1 (in budding yeast)/PCID2 (in human). Repression of pci2 expression inhibited both growth and mRNA export. And over-expression of pci2 also exhibited growth retardation with slight accumulation of $poly(A)^+$ RNA in the nucleus. Moreover, yeast two-hybrid and co-immunoprecipitation analysis showed that the Pci2 protein physically interacted with Sac3 and Dss1, which are members of TREX-2 complex. These observations support that the S. pombe Pci2 protein, as a component of TREX-2 complex, is implicated in mRNA export.

• Korean Journal of Microbiology
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• v.55 no.2
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• pp.112-116
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• 2019

Thp1/PCID2 is a subunit of the evolutionally conserved TREX-2 complex, which is required for transcription-coupled mRNA export from the nucleus to the cytoplasm. In fission yeast, Schizosaccharomyces pombe, there are two orthologs of the Thp1/PCID2 protein. In addition to pci2 (SPBC1105.07c) gene, SPAC1B3.08 gene encodes a PCI domain-containing protein that is predicted as a component of TREX-2 complex. Overexpression of SPAC1B3.08 cause slight defects of both growth and mRNA export. Yeast two-hybrid and co-immunoprecipitation analysis exhibits that the SPAC1B3.08 protein interacted with Sac3 and Dss1, which are another components of TREX-2 complex. These observations support the possibility that the S. pombe SPAC1B3.08 protein, as a component of TREX-2 complex, is involved in mRNA export.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2019.10a
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• pp.42-42
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• 2019

한국생명공학연구원은 1985년 설립된 이후로 현재까지 국가적 연구개발 수요에 대응하여 바이오 분야의 기초 원천 연구, 인프라 구축 및 운영을 통하여 우리나라 생명과학기술 발전에 힘써왔다. 특히 2006년부터는 해외생물자원의 중요성에 주목하여 차세대 국가 핵심 전략 BT산업의 필수 원자재인 생물소재의 범지구적 확보, 보존 및 관리를 위하여 해외생물소재센터를 설치하였다. 이후 차례로 중국, 코스타리카, 인도네시아, 베트남의 4개 거점 센터를 개소 및 운영하여 권역별 해외생물소재의 공동연구 및 국제협력 네트워크를 구축하고 효과적인 소재 확보 및 관리를 도모하고 있다. 이와 같이 확보된 소재는 36개국에서 채집된 약 318과 3,406속의 36,500여점 (2019년 9월 기준)에 달하고 소재의 확증표본은 해외생물소재센터 식물표본관(KRIB)에 보관 중이다. KRIB표본관은 2000년 Index Herbariorum에 등록되었으며, 약 80,000여점의 건조표본을 소장하고 있다. 분류군수는 과별로 콩과>국화과>꼭두서니과 순으로 많았으며, 국가별로는 중국>베트남>코스타리카 순으로 조사되었다. 한국생명공학연구원 해외생물소재센터 및 식물표본관은 소재의 정확한 동정을 위한 분류학적 시설로서의 역할뿐 아니라 누구에게나 개방된 홈페이지를 통하여 해외소재의 표본정보, 표본이미지 및 민속학적 정보와 활성 등 가치 있는 정보를 제공하여 연구자들에게 다양한 활용지원 서비스를 제공하고 있다.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2019.10a
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• pp.99-99
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• 2019

한국생명공학연구원 해외생물소재센터는 해외생물소재 확보 및 활용연구를 통하여 차세대 국가핵심전략 BT산업의 필수원자재인 생물소재의 범지구적 확보와 보존 관리의 임무를 수행하고 있다. 이를 위해 권역별 해외생물소재 공동연구센터(중국, 코스타리카, 인도네시아, 베트남) 및 37개국과의 국제협력 네트워크를 구축하고 있다. 세계적 수준의 생물소재 국가 인프라 구축을 목표로 국내 산 학 연 연구자들에게 다양한 해외생물소재 공급을 통한 지속 가능한 바이오 경제 기반 구축을 지원하고 있다. 해외생물소재센터에서는 2006년부터 특히 천연물 의약품 개발 분야에 많이 사용 되고 있는 해외 식물소재를 지속적으로 확보하고 있으며, 확보된 식물소재의 추출물 제조 및 추출물 은행을 구축, 이에 대한 생물활성 평가를 실시하며 연구자들에게 기초 자료로 제공하고 있다. 현재까지 총 36,500종의 해외식물소재를 확보하였으며, 추출물 약 320만점을 확보하였다. 확보된 소재의 분양활동을 통해 산 학 연 연구자들에게 180만여 점을 분양하였으며, 이를 활용한 다수의 논문과 특허를 획득하였고 중대형 기술이전을 실시하였다. 해외생물소재센터는 홈페이지 기반 분양 신청 시스템[https://www.ibmrc.re.kr]을 통하여 해외식물소재(Powder 와 Extact 형태) 분양서비스를 제공하고 있다. 또한 소재가치제고 연구를 통한 산업화 지원과 해외생물소재의 표본정보 서비스, 해외거점센터를 활용한 현지정보 제공 서비스를 지원하고 있다.