• Title/Summary/Keyword: 고밀도콜레스테롤

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Gender Difference in Associations between Serum Cholesterol Levels and Depression Symptoms in Healthy General Population (건강한 성인에서 성별에 따른 혈중 콜레스테롤 농도와 우울증상의 연관성 : 후향적 의무기록 조사)

  • Lee, So Hee;Park, Mina;Yoon, Dae Hyun;Lee, Young;Kim, Sun Shin
    • Korean Journal of Psychosomatic Medicine
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    • v.25 no.1
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    • pp.27-32
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    • 2017
  • Objectives : The purpose of this study was to determine the association between serum lipid profiles and depression according to gender difference. Methods : This retrospective cohort study included 27,452 subjects(15044 men and 12408 women) who underwent health examination. The duration was from January 2013 to December 2013. We estimate the correlation between serum lipid profile and Beck Depression Inventory(BDI) scores. We compare the effect size using beta coefficient. Results : In men, serum Triglyceride level was correlated positively with BDI scores(r=0.020, p<0.01). Serum LDL-C and HDL-C were negatively correlated with BDI scores(r=-0.015, p<0.01 ; r=-0.016, p<0.05). In women, Triglyceride level was also correlated positively with BDI scores(r=0.020, p<0.01), Serum HDL-C were negatively correlated with BDI scores(r=-0.019, p<0.01). There was no statistical significance between Serum LDL-C and Beck Depression Inventory(BDI) score. Conclusions : Both men and women had more depressive symptoms when they had low serum HDL-C level or high serum Triglyceride level. The depression symptoms were more severe when serum LDL-C level was low only in men.

The Relationship Between Lumbar Spine Bone Mineral Density and Cardiovascular Risk Factors in Premenopausal and Postmenopausal Women (폐경 전후 여성의 요추 골밀도와 심혈관 위험인자와의 연관성)

  • Kim, Mi-Young
    • Journal of radiological science and technology
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    • v.30 no.4
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    • pp.365-371
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    • 2007
  • Recent studies suggest a possible pathogenic linkage between the osteoporosis and atherosclerosis. We investigated the relationship between cardiovascular risk factors, including high sensitivity C-reactive (hs-CRP), hs-CRP and bone metabolism in females. Anthropometric measurements were performed on 300 women, and cardiovascular risk factors, including fasting blood glucose, lipid profiles and hs-CRP. An atherogenic index was calculated using the serum total cholesterol level divided by the high-density lipoprotein cholesterol level. The lumbar spine bone mineral density was measured using dual X-ray abosorptiometry. By bivariate analysis, the lumbar spine BMD showed negative correlations with age, systolic and diastolic blood pressures, serum total cholesterol, high-density lipoprotein cholesterol. The Age, BMI and high-density lipoprotein cholesterol showed significant correlations with the lumbar spine BMD. From linear regression analyses of all the study subjects, age, high-density lipoprotein cholesterol were found to be determinants of the lumbar spine BMD($R^2=0.272$).

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The correlation between triglyceride to HDL cholesterol ratio and metabolic syndrome, nutrition intake in Korean adults: Korean National Health and Nutrition Examination Survey 2016 (한국 성인에서 중성지방/고밀도지단백콜레스테롤 비와 대사증후군 및 영양소 섭취와의 연관성 : 2016년 국민건강영양조사 자료를 이용하여)

  • Kim, Youngjon;Han, A Lum
    • Journal of Nutrition and Health
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    • v.52 no.3
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    • pp.268-276
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    • 2019
  • Purpose: Metabolic syndrome causes diabetes and increases the risk of cardiovascular disease. This study examined the correlation between metabolic syndrome, nutrition intake, and triglyceride (TG)/high-density lipoprotein (HDL) cholesterol ratio. Methods: Using the data from the $7^{th}$ KNHANES (2016), this study was conducted on healthy adults aged 19 and older. The components and existence of metabolic syndrome and nutrition intake were independent variables and the TG/HDLcholesterol ratio was a dependent variable. A complex sample logistic progress test was used with age, sex, smoking, and drinking frequency corrected. Results: The TG/HDLcholesterol ratio of people with metabolic syndrome was as high as 1.314 on average, compared to people without metabolic syndrome (p < 0.0001). Among each component of metabolic syndrome, the TG/HDL cholesterol ratio had a significant association with fasting blood glucose, TG, HDL cholesterol, and waist circumference (p < 0.05). Only energy and carbohydrate intake were significantly related to the TG/HDLcholesterol ratio (p < 0.05). Conclusion: The TG/HDLcholesterol ratio is associated with each component of metabolic syndrome, but in particular, it is positively correlated with the presence of metabolic syndrome. Lower energy intakehad a positive correlation with the TG/HDLcholesterol ratio. These results show that metabolic syndrome can be predicted using the TG/HDLcholesterol ratio, and a diet strategy through nutrition and health education is necessary to prevent metabolic syndrome.

The Relationship Between Serum Triglyceride/HDL Cholesterol, Total Cholesterol/HDL Cholesterol, LDL Cholesterol/HDL Cholesterol Ratios and Cardiovascular Disease Risk Factors in Korean Adults: Using the 2016 Korea National Health and Nutrition Examination Survey Data (한국 성인에서 혈청 중성지방/고밀도 콜레스테롤, 총 콜레스테롤/고밀도 콜레스테롤, 저밀도 콜레스테롤/고밀도 콜레스테롤 비와 심혈관 질환 위험요인들과의 관련성: 2016년도 국민건강영양조사 자료를 이용하여)

  • Yoo, Areum;Shin, Saeron
    • Journal of The Korean Society of Integrative Medicine
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    • v.7 no.3
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    • pp.127-139
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    • 2019
  • Purpose : The lipid profile is a major predictive index for cardiovascular disease, but there have only been a few studies conducted on the relationship between lipid ratio and cardiovascular disease risk factors in the Korean population. To address this research gap, we investigated the association between three lipid ratios and cardiovascular disease risk factors among Korean adults. Methods : This study used data from the seventh Korea National Health and Nutrition Examination Survey conducted in 2016. Lipid ratios included triglyceride (TG)/high density lipoprotein cholesterol (HDL), total cholesterol (TC)/HDL, and low density lipoprotein cholesterol (LDL)/HDL. Cardiovascular risk factors included in this research were: systolic blood pressure $(SBP){\geq}140$, diastolic blood pressure $(DBP){\geq}90$, fasting blood sugar $(FBS){\geq}126$, $HbA1c{\geq}6.5$, body mass index $(BMI){\geq}25$, waist circumference (WC) $men{\geq}90$, $women{\geq}85$, and metabolic syndrome (MetS). A complex samples logistic regression test was performed to analyze the association between lipid ratios and cardiovascular disease risk factors. Results : 1) TG/HDL ratio had statistically significant relationships with DBP, FBS, HbA1c, BMI, WC and MetS. 2) TC/HDL ratio was correlated to SBP, DBP, FBS, BMI, WC, and MetS. 3) LDL/HDL ratio had association with BMI, WC, and MetS. Conclusion : We identified significant association between lipid ratios and cardiovascular disease risk factors. The three lipid ratios were particularly strongly associated with BMI, WC, and MetS.

The High-density lipoprotein (HDL) cholesterol and related factors in Korean middle-aged (한국 중년의 고밀도지단백(HDL) 콜레스테롤과 관련요인)

  • Kim, Sang-Lak;Kam, Sin;Kim, Myung-Gwan
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.4
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    • pp.423-432
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    • 2018
  • The purpose of this study was to provide basic data to promote health in middle-aged Koreans (40-59 years old) by understanding health behaviors that affect high-density lipoprotein (HDL) cholesterol level among various health behaviors. In a national health and nutrition survey, raw data combined on a total of 7,406 persons, IV-3 (2009), V-1 (2010), V-2 (2011), V-3 (2012), and VI-1 (2013), were selected as the final analysis subjects. HDL cholesterol was divided into two groups: less than 40 mg/dl and more than 40 mg/dl. The results of multiple logistic regression analysis were as follows: OR=3.916 for males, OR=3.439 for normal than low weight, OR=7.336 for obesity than low weight, OR=1.629 for alcohol consumption, OR=1.498 for smokers, OR=1.426 for don't practice moderate physical activity, OR=1.264 for no walking exercise, OR=1.510 for carbohydrates normal intake than low intake, OR 1.787 for carbohydrates over intake than low intake when HDL cholesterol increased from 40 mg/dl to less than 40 mg/dl. Korean middle-aged high-density lipoprotein (HDL) cholesterol levels should be increased to maintain proper health through aerobic exercise, smoking cessation, proper drinking habits, obesity relief, healthy eating out, and healthy food choices. This requires continuous publicity and education within the community, and a social environment should be built that enables health behavior to be practiced in daily life.

Effects of Tai Chi on Cardiovascular Disease Risk Factors among the Korean Elderly

  • Cho, Byung-Jun;Kim, Seon-Rye
    • Journal of the Korea Society of Computer and Information
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    • v.27 no.10
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    • pp.195-202
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    • 2022
  • This study explored the effects of Tai Chi on cardiovascular disease(CVD) risk factors among the Korean elderly. 68 elderly were selected and divided into two groups: an experiment group(34 patients) and a control group(34 patients). The experimental group practiced Tai Chi for 60 minutes a day, five times per week for 6 weeks total. The control group continued their routine levels of activity. CVD risk factors evaluated in both groups including body mass index, fasting blood sugar, triglyceride, high density lipoprotein cholesterol(HDL-C), and low density lipoprotein cholesterol(LDL-C). Each factor was measured before and after the 6-week intervention. Results showed that the experimental group had a significant decrease in measurements of body mass index, fasting blood sugar, triglyceride, and LDL-C levels. The experimental group also had an increase HDL-C level. Based on such findings, we believe that Tai Chi exercise program would function as an effective intervention strategy for preventing CVD in the elderly. Therefore, it is recommended that health and medical service personnel should seek to apply Tai Chi intervention as a daily component of elderly care.

Effect of Catechins on Serum Lipids in Obese Women (카테킨 음용이 비만여성의 혈중 지질농도에 미치는 영향)

  • Choi, Won-Ho;Lee, Jung-Won
    • The Journal of the Korea Contents Association
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    • v.12 no.1
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    • pp.338-345
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    • 2012
  • This study was developed to test the effectiveness catechin beverage drinking as exercise supplementary food for obese women. The effects of catekin were determined by weight, total cholesterol, triglycerides, High density lipoprotein cholesterol, high density lipoprotein cholesterol. Twenty-seven obese women were participated in this study. Eight women were tea catechin drinking group, Nine women were exercise group, and ten women were tea catekin drinking-combined with exercise group. After catechin drinking or exercise conducted, blood lipid factor were analyzed. body weight and triglycerides low density lipoprotein cholesterol levels were significantly decreased in tea catekin drinking combined with exercise group (p<0.001) and exercise group (p<0.001). total cholesterol were significantly decreased in three groups (p<0.05). It is thought that together catechin drinking and exercise can maximize weight loss of obese woman and reducing of blood lipid factor.

A Study on the Xanthelasma in Middle aged Women (중년여성에게서 나타나는 안검 황색종 연구)

  • Ahn, Hyun-Soon
    • Journal of the Korean Society of Fashion and Beauty
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    • v.6 no.2
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    • pp.87-90
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    • 2008
  • Background: It has been debated that serum lipid levels of patients with xanthelasma are higher than those of normal persons. In Korean literature, there are two reports of this. Objective: Our purpose was to review the findings in patients with xanthelasma and compare the patients to normal persons in respect of serum lipid levels. Methods: Fifty-one patients with xanthelasma were reviewed. Results: Mean age was 51 years in man and 51 years in woman. The ratio of male to female patients was 1:2.7. Significant difference of serum HDL-cholesterol level was found between patients with normal lipid level and normolipidemic control subjects. Conclusion: Xanthelasma palpebrarum occurs frequently in middle-aged women and HDL-cholesterol level of patients with xanthelasma was lower than normolipidemic control subjects.

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Effect of the supplementation of Coconopsis lanceolata extract on lipid metabolism amelioration in type 2 diabetes mouse model induced by high fat diet (울릉도 섬더덕 추출물의 급여가 제2형 당뇨 동물의 지질대사 개선에 미치는 영향)

  • Yun, Won-Kap;Bae, Hyun-Ji;Kim, You-Jeong;Kwon, O Jun;Im, Moo Hyeog;Cho, Hyun Duk;Kim, Taewan
    • Food Science and Preservation
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    • v.21 no.1
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    • pp.107-113
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    • 2014
  • The present study was designed to investigate the antihyperlipidemic effect of Coconopsis lanceolata extract in C57BL/6J mice. The mice were divided into four groups: normal diet group (ND), high fat diet group (HFD), positive control group with 0.05% metformin (PC), Coconopsis lanceolata extract group (UCL). After 5 weeks of feeding, average body weight of the UCL group mice was slightly decreased, while that of the HFD group significantly increased) Also, liver and adipose tissue weights in the UCL group significantly increased. The levels of trigliceride (TG) and total in the plasma of UCL-supplemented group were significantly lower than those of high fat diet group. On the other hand, HDL-cholesterol level was increased. Expression level of proteins related with adipogenesis such as SREBP-1c, ACC, and FAS in the liver of the UCL group mice was much lower comparing with the HFD group mice. In conclusion, the results showed that the Coconopsis lanceolata extract possesses significant antihyperlipidemic effects in C57BL/6J mice.

Risk Factors of Non-alcoholic Steatohepatitis in Childhood Obesity (비만아에서 비알코올성 지방간염의 위험요인)

  • Yun, Eun-Sil;Park, Yong-Hun;Choi, Kwang-Hae
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.10 no.2
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    • pp.179-184
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    • 2007
  • Purpose: Obesity has recently emerged as a significant health problem in the pediatric population, and the prevalence of non-alcoholic fatty liver disease is increasing in tandem with a significant rise in childhood obesity. Therefore, this study was conducted to clarify the risk factors of non-alcoholic steatohepatitis in obese children. Methods: We enrolled 84 obese children who visited the pediatric obesity clinic at Yeung-Nam university hospital. The patients were divided into two groups based on their alanine aminotransferase (ALT) level (separated at 40 IU/L), and the mean of ages, total cholesterol levels, HDL-cholesterol levels, LDL-cholesterol levels, triglyceride (TG) levels, as well as the mean obesity index, and body fat percentage of the two groups were then compared. Results: When the mean of ages ($10.5{\pm}1.6$ vs. $10.7{\pm}2.0$ years), total cholesterol levels ($183.0{\pm}29.1$ vs. $183.7{\pm}31.3$ mg/dL), HDL-cholesterol levels ($53.0{\pm}10.2$ vs. $55.7{\pm}13.0$ mg/dL), LDL-cholesterol levels ($113.4{\pm}30.2$ vs. $113.0{\pm}30.0$ mg/dL), triglyceride levels ($99.4{\pm}62.9$ vs. $114.2{\pm}47.3$ mg/dL), obesity indexes ($44.7{\pm}12.2$ vs. $47.9{\pm}15.1%$), and body fat percentages ($32.7{\pm}5.0$ vs. $34.0{\pm}4.8%$) of group 1 (ALT${\leq}$40 IU/L) were compared with those of group 2 (ALT${\geq}$41 IU/L), no significant differences were observed (p>0.05). However, hypertriglyceridemia (TG${\geq}$110 mg/dL) was more frequent in group 2 than in group 1 (p=0.023). Conclusion: TG may be an important risk factor in non-alcoholic steatohepatitis and further study regarding the risk factors in non-alcoholic steatohepatitis is required.

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