• Journal of the Korean Chemical Society
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• v.46 no.6
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• pp.585-589
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• 2002

• Journal of the Korean Chemical Society
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• v.49 no.4
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• pp.389-398
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• 2005

• Journal of the Korean Chemical Society
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• v.49 no.4
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• pp.363-369
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• 2005

• Venture DIGEST
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• s.95
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• pp.40-41
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• 2006

행복한 인생은 하나의 과학이다. 행복이란 저절로 이루어지는 것이 아니라 '구체적인 계획'과 이에 따른 '지속적인 행동' 그리고 '성취'라는 연결고리를 통해서 나오는 결과물이기 때문이다. 지금부터 2006년 인생의 중간 점검에 들어가 보자. 이 작업은 당신의 희망찬 후반전을 구상하는 '2006년 하프타임 워크숍'이다.

• Proceedings of the Korean Nuclear Society Conference
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• 2002.10a
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• pp.393.2-393
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• 2002

• Applied Chemistry for Engineering
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• v.20 no.3
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• pp.335-338
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• 2009

As important intermediates for blue emitting materials of organic light-emitting diodes, bromotriphenylethylene derivatives for distrylarylenes are prepared by reactions of bromobenzophenone with benzylphosphonates. The reaction produces a 60 : 40 mixture of (Z)- and (E)-geometric isomers that are difficult to be resolved. The (Z)-isomer is successfully isolated by a selective recrystallization process using 2-propanol as a solvent. The X-ray structure analysis of (Z)-isomer shows that dihedral angles between tert-butylphenyl ring and bromophenyl ring and between bromophenyl ring and phenyl ring are $56.5(4)^{\circ}$ and $74.1(4)^{\circ}$, respectively.

• Journal of Korean Medicine Rehabilitation
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• v.18 no.1
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• pp.95-110
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• 2008

목 적 : 급성 및 만성 염증 질환은 iNOS에 의해서 생성된 과량의 NO와 관련이 있다. 따라서 이러한 질병 치료를 목적으로 NO 생성 억제물질 또는 iNOS 발현 차단물질을 개발할 가치가 있다. 본 연구는 대사 안정성을 개선시킨 dimethoxycurcumin (DiMC)이 활성화된 대식세포에서 NO 생성 및 iNOS 발현을 제어할 수 있는지 조사하였다. 방 법 : RAW264.7 세포를 DiMC (양쪽 방향성 고리에 각각 2개의 methoxy group을 가짐), curcumin (양쪽 방향성 고리에 각각 1개의 methoxy group을 가짐), bis-demethoxycurcumin (양쪽 방향성 고리에 methoxy group이 없음; BDMC) 및 tetrahydrocurcumin (양쪽 방향성 고리에 각각 1개의 methoxy group을 가지고 있지만 중앙 7개 탄소 사슬에 이중결합이 없음; THC)로 각각 전처리한 후에 LPS로 자극하였다. 이들 전처리 물질의 효과를 비교하기 위하여, NO 생성, iNOS 발현, NF-kB p65 인산화 및 p65 DNA-binding 활성을 조사하였다. 결 과 : DiMC, curcumin 및 BDMC는 NO 생성, iNOS 발현 및 NF-kB 활성을 억제하였으며, 그 세기에 있어서 DiMC가 가장 크게 관찰되었고 그 다음 curcumin 그리고 BDMC 순으로 관찰되었다. THC는 어떠한 활성도 보이지 못했다. 결 론 :DiMC는 NO 생성 억제, iNOS 발현 차단 및 NF-kB 비활성을 유도할 수 있음을 알 수 있었다. 이러한 효과는 연속된 이중결합 및 methoxy group의 증가와 관련이 있는 것으로 판단된다.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.18 no.2_spc
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• pp.247-260
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• 2020

A multi-regression model was developed to estimate the decommissioning cost for Kori unit 1 using foreign nuclear power plant (NPP) decommissioning cost data. First, the decommissioning cost data were collected for 13 boiling water reactors and 16 pressurized water reactors and converted into the values as of November 2019. Then, for the regression model, the decommissioning cost was chosen as the dependent variable, and two variables were selected as independent variables: a contamination factor that was designed to reflect the operational characteristics of the decommissioned NPP and the decommissioning period. A statistical package in the R language was used to derive the regression model. Finally, the regression model was applied to estimate the decommissioning cost for Kori unit 1. The estimated decommissioning cost for Kori unit 1 was 663.40~928.32 million US dollars (782,812~1,095,418 million Korean won).

• Applied Chemistry for Engineering
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• v.18 no.6
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• pp.562-567
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• 2007

The stereoselective synthesis of chiral terminal epoxide is of immense academic and industrial interest due to their use as versatile starting materials as well as chiral intermediates. In this study, new polymeric chiral Co(salen) complexes bearing tallium (III)chloride and iron (III)chloride (ferric chloride) have been synthesized and characterized. Their catalytic activity and selectivity have been demonstrated for the asymmetric ring opening of various terminal epoxides using water and phenol derivatives as nucleophiles. The easily prepared polymeric complexes exhibited very high enantioselectivity for the asymmetric ring opening of epoxides with $H_2O$ and phenol nucleophiles, providing enantiomerically enriched terminal epoxides (> 98% ee). The system described in this work is very efficient for the synthesis of chiral epoxide, 1,2-diol and ${\alpha}$-aryloxy alcohol intermediates.

• Journal of the Korean Chemical Society
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• v.27 no.5
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• pp.368-375
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• 1983

The reactions of various 5-aryl-1,3,4-oxathiazol-2-ones with triethylphosphite resulted in the formation of the corresponding benzonitriles and ethylphosphorothioate by desulfurization reaction in 66∼94% yields. 5-(4-Nitrophenyl)-1,3,4-oxathiazol-2-one was also reacted with trimethylphosphite, triethylphosphine, and triphenylphosphine to give 4-nitrobenzonitrile. But it did not react with triphenylphosphate. The reactions of 5-(4-bromophenyl)-1,2,4-dithiazol-3-one with triphenylphosphine resulted in the formation of 4-bromothiobenzoyl isocyanate and triphenylphosphine thioxide. The thioacyl isocyanate was fragmented into nitrile in ether but was stable in chloroform. This desulfurization reaction observed in each reaction may proceed by the intramolecular rearrangement after insertion of the phosphorus compound into the ring. The stable thioacyl isocyanate in chloroform reacted with imine to give 1,3,5-thiadiazin-4-one via 1,4-cycloaddition reaction.