• Journal of the Korean Society of Radiology
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• v.8 no.5
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• pp.231-240
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• 2014

The purpose of this study were to analyze that the Seoul neuropsychological screening battery (SNSB) for the evaluating cognitive assessment of the Parkinson's disease patients with mild cognitive impairment (PD-MCI) and the changes of the cerebral ventricle volume in the brain magnetic resonance imaging (MRI), and we has been bring forward the guideline to determine the diagnostic criteria for the PD-MCI. To achieve this, we was diagnosed with Parkinson's disease patients (PD-MCI group: 34 patients; Parkinson's disease with normal cognition, PD-NC group: 34 patients) to perform the SNSB test for the attention, language, memory, visuospatial, and frontal/executive functions and the brain MRI. Additionally, to compared the change of the cerebral ventricle volume, we performed the brain MRI for the 32 normal control (NC) group. The volumetric analysis for a specific cerebral ventricle performed by using Freesurfer Ver. 5.1 (Massachusetts general Hospital, Boston MA, USA). As a results, compared to the PD-NC group, the PD-MCI group were statistically significant reduction in the ability to perform the memory and the visuospatial function (p<0.05). The volumetric changes for a specific cerebral ventricle were statistically significant variation in the left and right lateral ventricle, left and right inferior lateral ventricle, and 3rd ventricle. Although, in order to compared the objectification, the normalized percentage applied to the volumetric changes showed to extend the PD-MCI group than the PD-NC group. Specially, the left and right ventricle extension for the PD-MCI patients conspicuously had showed a quantitative linear relationship between the memory and the visuospatial function for the SNSB (r>0.5, p<0.05). Therefore, we were able to judge the diagnostic criteria of the PD-MCI through that can observe the volumetric variation of the specific cerebral ventricle by using Freesurfer in brain MRI, and to analyze the correlation between the SNSB.

• Journal of Digital Convergence
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• v.20 no.3
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• pp.517-527
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• 2022

This study aimed to compare changes in cognitive function, depression and ability to perform activity of daily living (ADL) in patients with dementia, mild cognitive impairment (MCI), and ischemic stroke (IS) and to identify factors associated with changes in instrumental ADL. A total of 86 patients (dementia=30, MCI=32, and IS=24) were included to analyse cognitive function, depression, and basic and instrumental ADL obtained at the time of diagnosis and 1 year after baseline. Repeated measures analysis of variance and multiple linear regression were used. A significant group by time interaction was found in executive function (p=.037) and instrumental ADL (p=.023) across groups. The MCI group has little change in executive function and instrumental ADL from the baseline to 1 year after diagnosis while other two groups showed changes with the dementia group showing declines and the group of IS having improvement in these factors over time. Changes in executive function(p=.030) and basic ADL (p<.001) explained 26.9% in the variance of changes in instrumental ADL. These findings showed a different changing pattern in executive function during the first year after diagnosis of dementia, MCI, and IS which have cognitive changes as their main symptoms, probably leading to a different changing pattern in instrumental ADL. Healthcare professionals should routinely assess for executive function and instrumental ADL problems and intervene to maintain and improve these functional outcomes immediately after disease.

• Journal of the Korea Society of Computer and Information
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• v.27 no.7
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• pp.125-135
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• 2022

In this study, using KLoSA data, it was verified whether subjective expectations and depression had a multi-mediated effect on life satisfaction of the elderly with dementia and mild cognitive impairment. As a result of the analysis, first, it was analyzed that the higher the IADL of the elderly with dementia and mild cognitive impairment, the lower the subjective expectation, the higher the depression, and the lower the life satisfaction. Second, it was analyzed that as the subjective expectations of the elderly with dementia and mild cognitive impairment increased, depression decreased and life satisfaction increased. Third, it was analyzed that IADL in the elderly with dementia and mild cognitive impairment not only directly affects life satisfaction, but also indirectly affects life satisfaction through subjective expectations and depression, so it has a multi-mediated effect. Therefore, it is necessary to expand subjective expectations by expanding service providers that can support daily life restrictions for the elderly with dementia and mild cognitive impairment, providing regular programs by experts to reduce depression, and establishing new national pension benefits for dependents.

• The Journal of Korean society of community based occupational therapy
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• v.9 no.1
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• pp.25-34
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• 2019

Objective : The purpose of this study was to investigate the effect of cognitive level of mild cognitive impaired elderly living in the community on participation in activities and social networks as well as leisure and daily life activities. Methods : The elderly people aged 65 years or older living in the community were selected for the mild cognitive impairment with a score of MMSE-K of 15 or more and 23 or less. MoCA-K was applied in order to examine the cognitive abilities of the subjects and K-ACS and LSNS-18 were applied to confirm the activity participation level and social network index. Results : As a result of examining the relationship between cognition and activity participation, various sub-abilities(spatio-temporal abilities, vocabulary abilities, attention, abstract thinking) of cognition had a significant influence on instrumental activities of daily living, leisure activities and social activities. In addition, all of the sub - abilities of cognition showed a significant correlation with sub-elements of social network. Conclusion : Through this study, it was found that the general elements of cognition influenced activity participation and social network of various areas of mild cognitive impaired elderly people. We suggest that measures for enhancing participation and social participation of the elderly with mild cognitive impairment are provided through follow up studies.

• Journal of Industrial Convergence
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• v.21 no.12
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• pp.101-111
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• 2023

This study conducted systematic review and meta-analysis to analyze the effectiveness of a dual-task for cognitive function in patients with MCI in Korea. A search was conducted using eight databases, and the search terms were MCI, cognition, and dual task. This study includes RCT and nonRCT published from January 2013 to July 2023. A total of 682 studies were searched, and 8 studies that fulfilled the inclusion and exclusion criteria were finally analyzed. Methodological quality was assessed with the RoB, RoBANS. The meta-analysis used CMA 4.0 ver. As a result of the analysis, the overall effect size of the dual task was medium effect size. The effect size according to the outcome variables was large for orientation and executive function, and medium effect size for global cognitive function, visuospatial function, memory, and attention. As a result of analysis according to the intervention period, the effect was greater when applied for 4 to 8 weeks, and the effect size was larger when applied for 24 to 30 sessions. This study presented clinical evidence on the effectiveness and application method of a dual-task applied to improve cognitive function in patients with MCI.

• Journal of Society of Occupational Therapy for the Aged and Dementia
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• v.12 no.2
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• pp.107-115
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• 2018

Objective : The purpose of this study is to investigate the effect of a group occupational therapy program on the depression and quality of life of the elderly with Mild Cognitive Impairment(MCI). Method : The elderly with Mild Cognitive Impairment were selected based on the Mini Mental State Examination-Dementia Screening(MMSE-DS). The group occupatinal therapy program consisted of various cognitive domains and was performed 12 times for 6 weeks. The Geriatric Depression Scale(SGDS-K) and Quality of Life(QOL) were used to assess depression and quality of life of the subjects before and after the intervention. Result : The elderly with MCI improved significantly on the SGDS-K and QOL after the intervention program(p<0.05). Particularly, in some items of the QOL, there was a statistically significant difference, but the results of the SGDS-K and QOL did not show any correlation(p>0.05). Conclusion : In the case of the elderly with MCI, the QOL scale and the depressive symptom test were statistically significant when the group occupational therapy program was applied for 6 weeks.

• Journal of Industrial Convergence
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• v.20 no.10
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• pp.39-49
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• 2022

The purpose of this study was to systematic review about randomized controlled trials the characteristics and effect of non-pharmacological intervention on depressive symptom in elderly with mild cognitive impairment. We searched studies published from January 2011 to July 2021 in 3 databases. A total 1,455 studies were found and included 11 studies in final analysis. Methodological quality was assessment with the Cochrane's RoB(risk of bias) tool. Geriatric Depression Scale(GDS) was the most used as the assessment tool for identifying the depressive symptom. Intervention were yoga, psychosocial intervention, cognitive training, health education, multi-component intervention, game training, aerobic/pulmonary physiotherapy, art therapy, music reminiscence activity, memory specificity training, cognitive stimulation therapy and SWTW(sleep well, think well) program. Among the intervention programs, yoga, multi-component intervention and game training were effective in improving depressive symptom. This study provided a clinical evidence for planning and implementing intervention on depressive symptom in elderly with mild cognitive impairment.

• The Journal of the Convergence on Culture Technology
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• v.9 no.2
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• pp.67-71
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• 2023

The purpose of this study is to investigate the effect of a community-based cognitive stimulation program on cognitive function and subjective memory in the elderly with mild cognitive impairment. This study was applied by selecting 15 users who understood the purpose of this study and agreed to participate in the shelter program for more than 3 months from April 2019 to August 2019 at the D Dementia Center in G located, Gyeonggi-do. The program consisted of a total of 36 cognitive stimulation programs 3 times a week a total of 3 months. Cognitive stimulation program stimulates cognitive function through various activities such as orientation reinforcement, cognitive training, recall, music, art, and physical play, and is used for the purpose of improving social function. It consists of folk songs, percussion instruments, national gymnastics, dance, games, and traditional games. As a result of the cognitive stimulation program, the average cognitive function increased by 2.13 points from 26.33 points before implementation to 28.46 points after implementation, and a statistically significant result was obtained (p=0.000). Subjective memory decreased by 3.53 points from the average of 7.13 points before the cognitive stimulation program was implemented to 3.60 points after the implementation, and a statistically significant result was obtained (p=0.000). It can be confirmed that this works. Dementia is leading to a cost burden, and congnitive function decreases the aqulity of life. It brings various burdens. It is necessary to study cognitive stimulation programs applied to various environments in the future.

• Korean Journal of Psychosomatic Medicine
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• v.26 no.2
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• pp.119-126
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• 2018

Objectives : The aim of this study is to investigate correlation between degree of white matter hyperintensities (WMH) and neurocognitive function along with behavioral and psychological symptoms of dementia (BPSD) in Korean patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI). Methods : Participants were 115 elderly subjects diagnosed with Alzheimer's disease or mild cognitive impairment in this retrospective study. WMH in brain MRI were rated with standardized visual rating scales (Fazekas scales) and the subjects were divided into two groups according to Fazekas scale. Cognitive function was evaluated with Korean version of the consortium to establish a registry for Alzheimer's Disease (CERAD-K), and BPSD was evaluated with Korean neuropsychiatric inventory (K-NPI). Independent t-test was performed to analyze the relationship between the degree of WMH and neurocognitive functions & BPSD. Results : Especially, the group with high severity of WMH showed significantly lower language fluency (p<0.05). In addition, the group with high severity of WMH showed significantly higher score in K-NPI. Conclusions : There was a significant association between WMH and neurocognitive test related with executive function. Moreover, WMH seems to affect BPSD severity. Evaluation of WMH would provide useful information in clinical settings.

• Journal of Digital Convergence
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• v.14 no.4
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• pp.449-457
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• 2016

This study aims to examine the effect of Convergence Tailed Occupational Therapy Activities Program (CTOTAP) which is customized to elderly people with mild cognitive impairment on their mental stability and social participation. A total of thirty elderly patients with mild cognitive impairment were randomly divided into a test group and a control group of 15 patients each, undergoing a total twelve sessions of the program (two sessions per week for six weeks) in three steps. In order to investigate the mental stability of the patients before and after the program, the Korean Geriatric Depression Scale (KGDS) was used while the Frenchay Activity Index (FAI) was used to explore the social participation of the patients. According to the findings of this study, there appeared to be an increase in the mental stability, social participation of the test group after the program. In addition, after the program there were differences between the test group and the control group in all of the mental stability and social participation. Therefore, the study has shown that the CTOTAP with customization has positive impact on the mental stability and social participation of patients with mild cognitive impairment.