DOI QR코드

DOI QR Code

The Effect of Dual Task Program on Cognitive Function in Patients with Mild Cognitive Impairment in Korea: A Systematic Review and Meta Analysis

국내 경도인지장애 환자에 적용한 이중과제 프로그램이 인지기능에 미치는 효과: 체계적 문헌 고찰 및 메타분석

  • Jae-Hun Jung (Dept. of Occupational Therapy, Kaya University)
  • 정재훈 (가야대학교 작업치료학과)
  • Received : 2023.09.26
  • Accepted : 2023.12.20
  • Published : 2023.12.28

Abstract

This study conducted systematic review and meta-analysis to analyze the effectiveness of a dual-task for cognitive function in patients with MCI in Korea. A search was conducted using eight databases, and the search terms were MCI, cognition, and dual task. This study includes RCT and nonRCT published from January 2013 to July 2023. A total of 682 studies were searched, and 8 studies that fulfilled the inclusion and exclusion criteria were finally analyzed. Methodological quality was assessed with the RoB, RoBANS. The meta-analysis used CMA 4.0 ver. As a result of the analysis, the overall effect size of the dual task was medium effect size. The effect size according to the outcome variables was large for orientation and executive function, and medium effect size for global cognitive function, visuospatial function, memory, and attention. As a result of analysis according to the intervention period, the effect was greater when applied for 4 to 8 weeks, and the effect size was larger when applied for 24 to 30 sessions. This study presented clinical evidence on the effectiveness and application method of a dual-task applied to improve cognitive function in patients with MCI.

본 연구는 국내 경도인지장애 환자의 인지기능을 위한 이중과제 프로그램의 효과를 분석하기 위해 체계적 문헌고찰 및 메타분석을 시행하였다. 8개의 데이터베이스를 사용하여 검색하였으며, 검색어는 경도인지장애, 인지, 이중과제였다. 2013년 1월부터 2023년 7월까지 출간된 문헌 중 무작위 및 비무작위 대조군 실험설계를 분석하였다. 총 682편의 문헌이 검색되어 포함 및 배제 기준을 충족한 8편의 문헌을 최종 분석하였다. 문헌의 질 평가는 RoB와 RoBANS를 사용하였다. 메타분석은 CMA 4.0 ver.을 사용하였다. 분석 결과 이중과제 프로그램의 전체 효과 크기는 중간 효과 크기였다. 결과변수에 따른 효과 크기는 지남력, 실행기능은 큰 효과 크기이며, 전반적 인지기능, 시공간기능, 기억기능, 주의기능은 중간 효과 크기였다. 중재 기간에 따른 분석 결과 적용 기간은 4~8주 적용이 효과가 더 크게 나타났으며, 총 회기에서는 24~30회기 적용의 효과 크기가 더 크게 나타났다. 본 연구는 경도인지장애 환자의 인지기능 증진을 위해 적용된 이중과제 프로그램의 효과 및 적용 방법에 대한 임상적 근거를 제시하였다.

Keywords

References

  1. National Institute of Dementia. (2023). Korean dementia observatory 2022. Seoul: National Institute of Dementia.
  2. E. G. Tangalos & R. C. Petersen. (2018). Mild cognitive impairment in geriatrics. Clinics in Geriatric Medicine, 34(4), 563-589. DOI : 10.1016/j.cger.2018.06.005
  3. R. C. Petersen et al. (2018). Practice guideline update summary: Mild cognitive impairment: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology. Neurology, 90(3), 126-135. DOI : 10.1212/WNL.0000000000004826
  4. T. R. Gure, K. M. Langa, G. G. Fisher, J. D. Piette & B. L. Plassman. (2013). Functional limitations in older adults who have cognitive impairment without dementia. Journal of Geriatric Psychiatry and Neurology, 26(2), 78- 85. DOI : 10.1177/0891988713481264
  5. S. Jongsiriyanyong & P. Limpawattana. (2018). Mild cognitive impairment in clinical practice: a review article. American Journal of Alzheimer's Disease & Other Dementias, 33(8), 500-507. DOI : 10.1177/1533317518791401
  6. T. L. Michaud, D. Su, M. Siahpush & D. L. Murman. (2017). The risk of incident mild cognitive impairment and progression to dementia considering mild cognitive impairment subtypes. Dementia and Geriatric Cognitive Disorders Extra, 7(1), 15-29. DOI : 10.1159/000452486
  7. J. A. Yates, L. Clare & R. T. Woods. (2013). Mild cognitive impairment and mood: a systematic review. Reviews in Clinical Gerontology, 23(4), 317-356. DOI : 10.1017/S0959259813000129
  8. S. Jhaveri, M. Romanyk, R. Glatt & N. Satchidanand. (2023). SMARTfit dual-task exercise improves cognition and physical function in older adults with mild cognitive impairment: results of a community-based pilot study. Journal of Aging and Physical Activity, 31(4), 621-632. DOI : 10.1123/japa.2022-0040
  9. A. Murillo-Garcia, J. L. Leon-Llamas, S. Villafaina, P. Rohlfs-Dominguez & N. Gusi. (2021). MoCA vs. MMSE of fibromyalgia patients: the possible role of dual-task tests in detecting cognitive impairment. Journal of Clinical Medicine, 10(1), 125. DOI : 10.3390/jcm10010125
  10. A. Bishnoi & M. E. Hernandez. (2021). Dual task walking costs in older adults with mild cognitive impairment: a systematic review and meta-analysis. Aging & Mental Health, 25(9), 1618-1629. DOI : 10.1080/13607863.2020.1802576
  11. Y. S. Jang & S. H. Bae. (2022). Effect of dual task program on cognitive function and balance ability in elderly with mild cognitive impairment. Journal of Occupational Therapy for the Aged and Dementia, 16(1), 41-50. DOI : 10.34263/jsotad.2022.16.1.41
  12. C. D. Park & J. M. Park. (2021). Effects of dual-task training in using the gait exercise program on gait pattern and cognitive function in elderly with mild cognitive impairment. Journal of Sport and Leisure Studies, 83, 363-378. DOI : 10.51979/KSSLS.2021.01.83.363
  13. K. A. Kim & O. S. Kim. (2015). The effects of exercise-cognitive combined dual-task program on cognitive function and depression in elderly with mild cognitive impairment. Korean Journal of Adult Nursing, 27(6), 707-717. DOI : 10.7475/kjan.2015.27.6.707
  14. H. Cooper, L. V. Hedges & J. C. Valentine. (2019). The handbook of research synthesis and meta-analysis. 3rd ed, Newyork, Russell Sage Foundation.
  15. M. Yan et al. (2022). Effects of virtual reality combined cognitive and physical interventions on cognitive function in older adults with mild cognitive impairment: a systematic review and meta-analysis. Ageing Research Reviews, 81, 101708. DOI : 10.1016/j.arr.2022.101708
  16. Q. Meng et al. (2022). The effect of combined cognitive intervention and physical exercise on cognitive function in older adults with mild cognitive impairment: a meta-analysis of randomized controlled trials. Aging Clinical and Experimental Research, 34(2), 261-276. DOI : 10.1007/s40520-021-01877-0
  17. National Evidence-based healthcare Collaborating Agency. (2011). NECA's guidance for undertaking systematic reviews and meta-analyses for intervention. Seoul: National Evidence-based healthcare Collaborating Agency.
  18. D. Moher, A. Liberati, J. Tetzlaff & D. G. Altman. (2009). Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Annals of Internal Medicine, 151(4), 264-269. DOI : 10.7326/0003-4819-151-4-200908180-00135
  19. L. Plonsky & F. L. Oswald. (2014). How big is "big"? interpreting effect sizes in L2 research. Lang Learn, 64(4), 878-912. DOI : 10.1111/lang.12079
  20. J. Higgins & J. Thomas. (2022). Cochrane handbook for systematic reviews of interventions ver. 6.3. Cochrane Training. https://training.cochrane.org/handbook/current/chapter-10
  21. J. H. Hwang & M. S. Park. (2018). Effect of a dual-task virtual reality program for seniors with mild cognitive impairment. Korean Journal of Clinical Laboratory Science, 50(4), 492-500. DOI : 10.15324/kjcls.2018.50.4.492
  22. M. K. Jeong. (2021). Effects of dual-task exercise program on cognitive function and physical fitness in mild cognitive impairment patients. Doctoral dissertation. Dong-A University, Busan.
  23. J. H. Lee, Y. S. Bang, E. S. Ju & M. J. Hwang. (2020). The effects of occupational therapy program using dual-task on cognitive function and gait for the elderly with mild cognitive impairment. Korean Journal of Occupational Therapy, 28(1), 109-125. DOI : 10.14519/kjot.2020.28.1.08
  24. M. S. Lee, J. D. Kim & B. J. Cho. (2022). Effect of participation in the dual-task dance sport program on the change of EEG, cognitive function and psychological happiness for the elderly with mild cognitive impairment. Culture & Convergence, 44(7), 755-766. DOI : 10.33645/c nc.2022.7.44.7.755
  25. S. Y. Park. (2019). The effects of cognitive task combined dual-task program on cognitive function and ADL with mild cognitive impairment. Master's dissertation. Kyungwoon University, Gumi.
  26. N. Ali et al. (2022). The effects of dual-task training on cognitive and physical functions in older adults with cognitive impairment: a systematic review and meta-analysis. The Journal of Prevention of Alzheimer's Disease, 9(2), 359-370. DOI : 10.14283/jpad.2022.16
  27. X. Liu, G. Wang & Y. Cao. (2023). Association of nonpharmacological interventions for cognitive function in older adults with mild cognitive impairment: a systematic review and network meta-analysis. Aging Clinical and Experimental Research, 35(3), 463-478. DOI : 10.1007/s40520-022-02333-3
  28. C. Udina et al. (2022). Dual-task related frontal cerebral blood flow changes in older adults with mild cognitive impairment: a functional diffuse correlation spectroscopy study. Frontiers in Aging Neuroscience, 14, 958656. DOI : 10.3389/fnagi.2022.958656
  29. J. H. Park. (2021). Effects of cognitive-physical dual-task training on executive function and activity in the prefrontal cortex of older adults with mild cognitive impairment. Brain & Neurorehabilitation, 14(3), e23. DOI : 10.12786/bn.2021.14.e23