• Journal of Biomedical Engineering Research
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• v.20 no.6
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• pp.547-553
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• 1999

생체재료로 사용되는 polyurethane(PU) 표면에 항혈전성 lumbrokinase(LK)를 고정함으로써 생체적합성을 향상시키고자하였다. 먼저 LK를 PU 표면에 고정하기 위한 가교제로서 4-azidoaniline hydrochloride와 poly(acrylic acid)를 이용하여 4-azidophenyl 작용기가 amido 결합으로 치환된 수용성, 광반응성 poly(acrylic acid)(PPa-II)를 합성하였다. H-nuclear magnetic reasonance spectrum(500MHz H-NMR)의 6-7 peak와 infrared spectrum (FT-IR) 의 2125.48 cm peak으로부터 PPA-II의 합성을 지원하였다. EH한 4-azidophenyl 작용기가 poly(acrylid acid) 잔기에 치환된 정도는 UV/VIS adpectrophotometric spectrum을 확인한 결과 11~14%임을 알 수있었다. 0.5 1및 5% PPA-II를 각각 광반응하여 얻은 PU는 39.5, 161.8 및 181.5 nmole/$\textrm{cm}^2$의 농도로 표면에 carvoxyl 작용기가 유도되었음을 알 수있었다. 0.05M KH2PO4 (pH 4.5) 용액에서 1-ethyl-3-(3-(dimethylamino)propyl)carbodiimide(EDC)를 촉매로 사용하여 LK를 PU표면에 amido 공유결합으로 고정하였으며, 이것은 지속적인 fibrinolytic 활성도를 보였다. PPA-II를 이용한 표면 개질 방법은 수용성 반응조건에서 이루어진다는 점과 광반응을 이용함으로써 특정부위에서의 표면개질이 가능하다는 점에서 그 응용가치가 크며 아울러 PU의 생체적합성을 향상시킬 수 있는 방법으로서 판단된다.

• Journal of The Korean Association of Information Education
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• v.21 no.3
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• pp.343-350
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• 2017

This current study employs multi-year design-based research to design and implement a course in teacher education in Korea. Specifically this paper reports our first attempt to work with 3 primary in-service teachers majoring in computer education. We have incorporated design thinking (DT) into the course design and investigated how primary teachers appreciate the role of DT and recognize the connection between teaching computational thinking and DT. This qualitative study reports the course design, its progression, reflections, and learning outcomes.

• Journal of the Korean Society of Propulsion Engineers
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• v.23 no.3
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• pp.18-27
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• 2019

The flow mixing characteristics for the heated dual jets were numerically studied by using URANS (unsteady Reynolds-averaged Navier-Stokes). The increased turbulent diffusion was obtained for the compressible flow, and the thermal diffusion of incompressible flow increased more than that of compressible flow. From the results of FFT and phase portraits, periodic and quasi-periodic states were observed as the jet spacing increased. It was observed that linear variations of merging points and combined points were different because unsteady flow determined the flow mixing characteristics for a large jet spacing.

• Journal of Broadcast Engineering
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• v.24 no.4
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• pp.564-572
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• 2019

With the development of deep learning, the performance of facial landmark detection methods has been greatly improved. The heat map regression method, which is a representative facial landmark detection method, is widely used as an efficient and robust method. However, the landmark coordinates cannot be directly obtained through a single network, and the accuracy is reduced in determining the landmark coordinates from the heat map. To solve these problems, we propose to combine integral regression with the existing heat map regression method. Through experiments using various datasets, we show that the proposed integral regression network significantly improves the performance of facial landmark detection.

• Journal of the Korean Society for Precision Engineering
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• v.15 no.8
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• pp.102-108
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• 1998

본 논문에서는 Nd-YAG 레이저 용접 프로세스를 이용하여 두께가 다른 STS304스테인레스 박강판을 대상으로한 점용접에 관한 연구로서, 레이저 용접은 미소부위에 효율적인 접합가공이 가능한 공정으로 비접촉식 가열원을 이용하기 때문에 접합공정 중 기계적 변형이 없고, 레이저 빔을 국부가열원으로 하여 매우 좁은 부분에 제한적으로 열을 가할 수 있어서 강한 금속적 결합이 요구되는 소형부품의 접합에 이용될 수 있다. 뿐만 아니라 공정 변수들을 변화시켜 실제 접합부에 들어 가는 입열량을 쉽게 제어할 수 있다는 등 많은 장점을 가지고 있다. 본 연구에서는 1mm이하의 스테인레스 박판에 대한 레이저 점용접을 FDM과 신경회로망을 이용하여 해석하고 용접부의 너겟 크기, 용접부 깊이 등의 형상을 예측하였다. 또한 레이저 점용접에 있어서의 주요 변수인 펄스 에너지, 펄스 타임, 박판의 두께, 두 판사이의 간극크기 등득 변화시켜 실험하고 수치해석을 검증하기 위하여 여러 가지 강에 대한 레이저 점용접 실험을 수행하였다. 또한 수치해석 시뮬레이션을 위하여 윈도우 프로그래밍을 개발하였다.

• Journal of Internet Computing and Services
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• v.14 no.6
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• pp.117-124
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• 2013

In this paper, we present a new method which efficiently estimates a face direction from a sequences of input video images in real time fashion. For this work, the proposed method performs detecting the facial region and major facial features such as both eyes, nose and mouth by using the Haar-like feature, which is relatively not sensitive against light variation, from the detected facial area. Then, it becomes able to track the feature points from every frame using optical flow in real time fashion, and determine the direction of the face based on the feature points tracked. Further, in order to prevent the erroneously recognizing the false positions of the facial features when if the coordinates of the features are lost during the tracking by using optical flow, the proposed method determines the validity of locations of the facial features using the template matching of detected facial features in real time. Depending on the correlation rate of re-considering the detection of the features by the template matching, the face direction estimation process is divided into detecting the facial features again or tracking features while determining the direction of the face. The template matching initially saves the location information of 4 facial features such as the left and right eye, the end of nose and mouse in facial feature detection phase and reevaluated these information when the similarity measure between the stored information and the traced facial information by optical flow is exceed a certain level of threshold by detecting the new facial features from the input image. The proposed approach automatically combines the phase of detecting facial features and the phase of tracking features reciprocally and enables to estimate face pose stably in a real-time fashion. From the experiment, we can prove that the proposed method efficiently estimates face direction.

• Microbiology and Biotechnology Letters
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• v.10 no.4
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• pp.245-252
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• 1982

The enzymes lytic to red yeast cell wall, which were produced by Penicillium lilacinum ATCC 36010 and Bacillus pumilus No 41, hydrolyzed an extracellular mannan from Rhodotonla glutinis IFO 0695. mannan was arranged with $\beta$-1,3 and $\beta$-1,4 linkages alternatively. Using this mannan, substrate specificities of these enzymes were investigated. The one from Penicillium lilacinum was an unique mannanase which hydrolyzed $\beta$-1,3 mannoside bond and the other from B. pumilus was a new type of mannanase which cleaved $\beta$-1,4 mannoside bond with requirement of the existence of $\beta$-1,3 linkage on the reducing side. Both enzymes released two kinds of oligosaccharide from mannan, respectively. However, the enzyme from Pen lilacinum produced tetrasaccharide and disaccharide and one of them, tetrasaccharide, was hydrolyzed to disaccharide further. The one from B. pumilus released tetrasaccharide and hexasaccharide from mannan finally.

• Journal of the Korean Institute of Telematics and Electronics C
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• v.36C no.5
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• pp.76-85
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• 1999

The intuitive understanding of the dynamic pattern generation in asymmetric networks may be useful for developing models of dynamic information processing. In this paper, dynamic behavior of the cyclic connection neural network, in which each neuron is connected only to its nearest neurons with binary synaptic weights of $\pm$ 1, has been investigated. Simulation results show that dynamic behavior of the network can be classified into only three categories: fixed points, limit cycles with basin and limit cycles with no basin. Furthermore, the number and the type of limit cycles generated by the networks have been derived through analytical method. The sufficient conditions for a state vector of $n$-neuron network to produce a limit cycle of $n$- or 2$n$-period are also given. The results show that the estimated number of limit cycles is an exponential function of $n$. On the basis of this study, cyclic connection neural network may be capable of storing a large number of dynamic information.

• Proceedings of the Korea Water Resources Association Conference
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• 2016.05a
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• pp.368-368
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• 2016

점착성 유사는 응집현상을 통해 크기와 밀도를 바꾸고 이에 따라 부유 및 이동에 큰 영향을 미치는 침강속도가 지속적으로 변화한다. 따라서 점착성 유사의 거동을 이해하기 위해서는 응집현상에 대한 고려가 필수적으로 이루어져야 한다. 현재까지 이루어진 응집현상 모형은 크게 Population balance equation type 모형(PBE)과 Floc growth type 모형(FGM)으로 나뉜다. PBE 모형은 점착성 유사의 입도분포를 모의할 수 있는 장점이 있는 반면에 닫힌 계에서 질량보존을 만족시키지 못하는 단점을 가진다. FGM 모형은 간단한 식을 통해 질량보존을 만족시키고 수치적으로 효율적인 모의를 할 수 있는 반면 입도분포를 모의할 수 없는 단점을 가진다. 이러한 장단점으로 인해 PBE 모형은 유사이동모형과 결합되어 이용된 사례가 없으며 FGM 모형은 유사이동모형과 결합되어 평균적인 점착성 유사의 거동만을 모의하는 연구에 이용되었다. 본 연구에서는 Stochastic floc growth type 모형(SFGM)의 개발에 따라 이해할 수 있는 점착성 유사이동의 특성과 이를 유사이동 모형과 결합시키는 방향에 대해 검토한다. 현재까지 진행된 연구 결과를 분석하면 SFGM은 질량보존을 만족시키면서도 점착성 유사의 입도분포를 모의할 수 있는 장점을 가지는 것으로 판단된다. 특히 난수발생의 단계에서 적절한 확률분포형을 선정하고 확률매개변수의 보정이 이루어지는 경우에는 높은 정확도를 가지는 입도분포 모의가 가능하다. 가는 모래를 대상으로 하는 비점착성 유사의 경우에는 추계학적인 유사이동 모형의 개발이 활발히 이루어져 왔다. 개발된 모형은 실제 측정값에 적용되어 다양한 학술적 가능성을 보여왔다. 따라서 SFGM의 개발이 점착성 유사의 이동모형과 결합되는 경우에는 점착성 유사가 지배적인 다양한 환경에서의 거동 특성을 이해할 때 매우 유용할 것으로 판단된다. 응집모형은 난류의 강도에 지배적인 영향을 받으며 유사의 입경 및 밀도 변화를 계산한다는 점을 고려할 때 유사이동 모형 역시 난류 강도에 대한 정보를 계산할 수 있는 지배방정식을 필요로 한다. 향후 개발될 추계학적 점착성 유사의 이동모형은 난류에 대한 정보, SFGM의 결합 등을 필요조건으로 가진다.

• The korean journal of orthodontics
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• v.33 no.5 s.100
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• pp.359-370
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• 2003

The purpose of this study was to evaluate the bond strength of orthodontic brackets bonded to metal bar with chemically cured adhesive (Ortho-one, Bisco Co, USA) in various types and directions of force application. Three types of metal bracket with different bracket base configurations; Micro-Loc base(Tomy Co, Japan), Chessboard base(Daesung Co, Korea), Non-etched Foil-Mesh base(Dentaurum, Germany); were used in this study. Peel, shear, tensile bond strengths were measured by universal testing machine and compared each other. The peel force directions applied were $0^{\circ},\;15^{\circ},\;30^{\circ},\;45^{\circ},\;60^{\circ},\;75^{\circ},\;90^{\circ}$ And then, in consideration of the different surface area of the bracket bases, the bond strength Per unit area were calculated and compared. The results obtained were summarized as follows: 1. The bond strengths according to the types and the directions of the forces were greatest at the shear forces in all three bracket base configuration groups(p<0.01). 2. As the peel force direction grew higher in degree, peel bond strength decreased. The Patterns of peel bond strength change according to force direction was similar in all three bracket base configurations. The minimum bond strength was 60 degree-peel bond strengths in all three bracket base configurations. 3. In Micro-Loc base group, minimum peel bond strength$(_{60}PBS)$ was in $29\%$ level of shear bond strength and $52\%$ level of tensile bond strength. In Chessboard base group, $_{60}PBS$ was in $34\%$ level of shear bond strength and $61\%$ level of tensile bond strength. In Non-etched Foil-Mesh base group, $_{60}PBS$ was in $34\%$ level of shear bond strength and $55\%$ level of tensile bond strength. 4. The bond strengths per unit area were lowest in Non-etched Foil-Mesh base group and highest in Chessboard base group(p<0.05). However, there were no differences in shear bond strength, tensile bond strength, $75^{\circ}\;and\;90^{\circ}$ per unit area between Micro-Loc and Chessboard base groups.