• Journal of Sensor Science and Technology
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• v.10 no.1
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• pp.1-8
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• 2001

Conventional microgyroscopes of vibrating type require resonant frequency tuning of the driving and sensing modes to achieve high sensitivity. These tuning conditions depend on each fabricated microgyroscopes, even though the microgyroscopes are identically designed. A new micromachined resonator, which is applicable to microgyroscopes with self-toning characteristics, is presented. Since the laterally driven two degrees of freedom (2DOF) resonator was designed as a symmetric structure with identical stiffness in two orthogonal axes, the resonator is applicable to vibrating microgyroscopes, which do not need mode tuning. A dynamic model of the resonator was derived considering gyroscopic application. The dynamic model was evaluated by experimental comparison with fabricated resonators. The microgyroscopes were fabricated using a simple 2-mask-process of a single polysilicon layer deposited on an insulator layer. The feasibility of the resonator as a vibrating microgyroscopes with self-tuning capability is discussed. The fabricated resonators of a particular design have process-induced non-uniformities that cause different resonant frequencies. For several resonators, the standard deviations of the driving and sensing frequencies were as high as 1232Hz and 1214Hz, whereas the experimental average detuning frequency was 91.75Hz. The minimum detuned frequency was 68Hz with $0.034mVsec/^{\circ}$ sensitivity. The sensitivity of the microgyroscopes was low due to process-induced non-uniformity; the angular rate bandwidth, however, was wide. This resonator could be successfully applicable to a vibrating microgyroscopes with high sensitivity, if improvements in uniformity of the fabrication process are achieved. Further developments in improved integrated circuits are expected to lower the noise level even more.

• Journal of the Korea Convergence Society
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• v.9 no.11
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• pp.29-35
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• 2018

In this paper, we proposed a high sensitivity sensor that can detect the concentration change of Nacl aqueous solutions by using a slot coupling capacitor resonator in sub-microwave band. The resonator applied to the sensor consists of a parallel plate capacitor connected to an inductive slot utilizing the ground plane of the microstrip line. Based on the measurement data of the dielectric characteristics according to the concentration change, the resonance frequency was determined in the UHF band where the concentration change is evident and the Nacl aqueous solution is inserted into the capacitor. Based on the simulation, the proposed resonator was designed and fabricated. The concentration level was varied from 0 to 400 mg/dl as 100 mg/dl step, and the transmission scattering coefficient ($S_{21}$) was successfully measured. Experimental results show that it is applicable to the concentration detection sensor in Nacl aqueous solution by obtaining minimum 1.8 dB($S_{21}$) at each step.

• Journal of the Korean Society of Radiology
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• v.14 no.5
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• pp.635-642
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• 2020

The purpose of this study was to analysis the effects of shielding area of field configuration with changing of sensitivity and density on tube current (milliampere-seconds, mAs) and image quality in automatic exposure control (AEC) system. The equipment used a digital radiography device (Digital Diagnost, Philips, Netherlands), which has a integral type with an X-ray tube and an indirect digital detector. The AEC system conditions were consisted of 9 setting environments, that mode changing of the sensitivity (S200, S400, S800) and the density (+2.5, 0, -2.5). The tube current evaluated automatically exposed mAs under 81 combination conditions crossed by AEC conditions in fixed at 40 kVp. The image quality evaluated the radiographic images that selected valid images by visual assessment the radiographic images of the self-produced conical pyramid phantom and then measured their signal to noise ratio (SNR). As a result, the maximum tube current was 60.0 mAs that automatically exposed conditions were the 100% of shielding area and the sensitivity of S200 and the density of +2.5. The minimum tube current was 0.9 mAs with non-shielding area and the sensitivity of S800 and the density of -2.5. When the shielded area 0% with the sensitivity of S200 and the density of +2.5, the maximum SNR was the highest as 25.2. But when the shielded area 25% with the sensitivity of S800 and the density of -2.5, the minimum SNR was the lowest as 4.7.

• KSBB Journal
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• v.24 no.1
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• pp.1-8
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• 2009

In the past decade, we have observed rapid advances in the development of biochips in many fields including medical and environmental monitoring. Biochip experiments involve immobilizing a ligand on a solid substrate surface, and monitoring its interaction with an analyte in a sample solution. Metal nanoparticles can display extinction bands on their surfaces. These charge density oscillations are simply known as the localized surface plasmon resonance (LSPR). The high sensitivity of LSPR has been utilized to design biochips for the label-free detection of biomolecular interactions with various ligands. LSPR-based optical biochips and biosensors are easy to fabricate, and the apparatus cost for the evaluation of optical characteristics is lower than that for the conventional surface plasmon resonance apparatus. Furthermore, the operation procedure has become more convenient as it does not require labeling procedure. In this paper, we review the recent advances in LSPR research and also describe the LSPR-based optical biosensor constructed with a core-shell dielectric nanoparticle biochip for its application to label-free biomolecular detections such as antigen-antibody interaction.

• The Journal of the Acoustical Society of Korea
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• v.8 no.1
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• pp.75-80
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• 1989

A Mach-Zehnder interferometer using single mode optical fiber was constructed which operates in homodyne detection scheme. Its response to air-borne soun pressure was examined experimentally. A signal stabilizer was developed for maintaining optical fiber interferometer in quadrature condition using a cylindrical piezoelectric stretcher. This maintains the optical fiber sensor at a maximum sensitivity in the presence of the phase drift caused by temperature fluctuation and other types of environmental disturbances.

• 전기의세계
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• v.20 no.5
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• pp.40-42
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• 1971

XY recorder는 10여년전부터 널리사용되어 오는 기록계로 2개의 자동평형전위차계로 X, Y축방향에 arm과 pen의 결합으로 양자의 좌표축의 교점에서 pen이 평형정지하는 상태에 기록지자체가 servo motor로 이동되어 기록이 가능하게 된다. 특히 타기록계에 비하여 고감도(Ex. 0.5V/cm), 고정도(Ex. 0.3%)임은 물론 y=f(x)인 x,y의 함수관계가 기록되어 타기록계에서는 얻기 어려운 특징이 있어, analog computer의 해의 기록계로서, 도한 각종 검출변환기를 전설치하여 vacuum tube 혹은 diode transistor의 특성곡선, 전기철판등의 자성재료의 자화곡선, 회전기의 회전수-전압, 전류, 출력, 효율곡선, 금속재료의 온도 혹은 인신장곡선, pipe valve의 유량-압력곡선등 전기.전지.기계.재료.물리.화학등의 다각도용도로서 연구실험은 물론 생산현장에 있어서의 시험. 정리. 감시등의 치용이 활발히 급진하는 경향에 비추어 이 기록계 사용에 고려되어야할 noise제거의 한 방법을 소개하고저 한다.

• Journal of the Korean Institute of Telematics and Electronics
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• v.25 no.11
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• pp.1282-1285
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• 1988

A novel temperature difference-to-frequency converter using two resistance temperature detectors (RTD) has been developed. The resistance difference of two RTD is converted into its equivalent inductance to form the resonant circuit of the Colpitts oscillator. The conversion sensitivity of 16 Hz/$^{\circ}C$ and the residual nonlinearity less than 2.15% over the temperature difference range from 35$^{\circ}C$ to 155$^{\circ}C$ are obtained by the prototype converter. The frequency drift of oscillator itself is $\pm$ 0.5Hz. Thus, the minimum detectable temperature difference is estimated to be $\pm$ 0.013$^{\circ}C$. The proposed coverter, except for two RTD, can be fabricated in monolithic IC form.

• Analytical Science and Technology
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• v.17 no.4
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• pp.322-336
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• 2004

The improved derivatization technique of tamoxifen metabolite in human urine is described for the acylation method that they are substituted by derivatization reagent like acyl anhydride for use of gas chromatography/mass spectrometry. The hydroxyl group of tamoxifen metabolite was derivatized by trifluoroacetic anhydride (TFAA), pentafluoroacetic anhydride (PFPA) and heptaflorobutylic anhydride (HFBA). It was investigated to the gas chromatography/mass spectrometry (GC/MS) technique use negative ion chemical ionization (NCI), positive ion chemical ionization (PCI) and electron impact (EI). In acylation of the metabolites of tamoxifen, the effective reaction temperature and time were shown to be at $50^{\circ}C$ for 30 min. The 4-hydroxytamoxifen, which is known to major metabolite of tamoxifen, was not detected in human urine, whileas the hydroxymethoxytamoxifen was detected. We thought that this result was from the single dose of tamoxifen.

• Proceedings of the Korean Vacuum Society Conference
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• 2011.08a
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• pp.389-389
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• 2011

최근 생체분자 구조 연구가 의료진단, 생명 현상 규명 및 의약품 개발 등 다양한 분야에 응용되고 있으나 대부분의 분석방법이 제한적이어서 새로운 기술 개발의 필요성이 증대하고 있다. 종래의 DNA 등의 생체분자의 분석은 형광염료를 이용한 방법이 주로 이용되었다. 형광염료는 단백질을 포함한 여러 물질들에 대해 반응하지 않기 때문에 분석에 제한이 있으며, 이와 같은 단점을 보완하는 방법으로 SPR (surface plasmon resonance) 분석법이 연구되었다. SPR은 형광염료 분석에 필수적인 레이블링(labeling) 등의 전처리 과정 없이 높은 민감도로 분석이 가능한 장점이 있다. 한편, 그래핀은 뛰어난 전자기적 성질과 기계적 성질 을 가지는 반금속(semimetal)으로, 실험실 규모에서 안정적인 합성이 실현되면서 그 응용 분야에 대한 연구가 활발히 이루어 지고 있다. 그래핀은 큰 표면적 대 부피비를 가지며, 이는 검출물질과의 반응성이 좋아야 하는 센서기술에 있어서 장점으로 작용한다. 특히, 비금속성을 띠는 단층 그래핀을 여러 장 겹치면 금속성을 갖게 되기 때문에 SPR 센서의 금속 필름으로 응용이 가능하다. 본 연구에서는 SPR 현상을 이용하는 광섬유 센서의 감도와 정확도를 증진시키기 위해 광섬유 표면에 그래핀을 적용하였다. 광섬유는 상부 피복과 클래딩을 제거하여 코어를 노출시킨 후, 다층 그래핀 필름을 코팅함으로써 검출부를 구성한다. 그 후, DNA-biotin 용액, DNA-biotin 용액, 그리고 Streptavidin 단백질 복합 용액에 대한 검출기 신호를 분석하였다. 구성된 센서에 각 용액을 1 ${\mu}{\ell}$ 씩 반응시켜 분광계로 파장에 따른 광강도를 측정하는 실험을 수행했으며, 450 nm에서 460 nm 범위의 푸른빛의 광원을 사용하였다. 그래핀 필름의 유무에 따라 확연히 구분되는 경향을 보이는 결과를 얻었고 그래핀 필름이 기존 SPR 센서의 금속박막을 대체 할 수 있음을 확인하였다.

• Analytical Science and Technology
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• v.26 no.1
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• pp.19-26
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• 2013

Gibberllic acid ($GA_3$) is one of gibberellins (GAs) that are a class of plant growth hormones that exert profound and diverse effects on plant growth and development. $GA_3$ is essentially non-UV absorbing and is difficult to assay by UV-detector. For effective extraction of gibberellic acid from fruits by using liquid-liquid extraction, optimized pH and extraction solvent were established. The selective and sensitive derivative of $GA_3$ for HPLC/UV-vis was derivatized using phenacyl bromide, and the experimental factors, including reaction time, reaction temperature and amount of derivatizing reagent and base were investigated for the effective synthesis. The derivatized $GA_3$ with phenacyl bromide was effectively analyzed by HPLC/UV-vis. The structure of derivatized $GA_3$ was confirmed by HPLC/ESI-MS. For apple, LOD and LOQ were 0.008 mg/kg and 0.027 mg/kg, respectively. For pear, LOD and LOQ were 0.003 mg/kg, 0.012 mg/kg, respectively. The established method can be applied to more effective analysis of $GA_3$ from plant and food.