• Journal of Life Science
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• v.30 no.8
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• pp.672-679
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• 2020

Distal myopathy is a clinically and genetically heterogeneous group of degenerative diseases of the distal muscle. Glycogen storage disease type IXD (GSD9D) is a metabolic distal myopathy characterized by muscle deficiency of phosphorylase kinase, a key regulatory enzyme in glycogen metabolism. Affected individuals may develop muscle weakness, degeneration, and cramps, as well as abnormal muscle pain and stiffness after exercise. It has been reported that mutations in the PHKA1 gene which encodes the alpha subunit of muscle phosphorylase kinase cause GSD9D. In this study, we examined a Korean GSD9D family with a c.3314T>C (p.I1105T) mutation in the PHKA1 gene. This mutation has not been previously reported in any mutation database nor was it found in 500 healthy controls. The mutation region is well conserved in various other species, and in silico analysis predicts that it is likely to be pathogenic. To date, only seven mutations in the PHKA1 gene have been documented, and this is the first report of Korean GSD9D patients. This study also describes and compares the clinical symptoms and pathological conditions of previously reported cases and these Korean patients. We believe that our findings will be useful for the molecular diagnosis of GSD9D.

• Journal of Industrial Convergence
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• v.17 no.4
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• pp.21-31
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• 2019

In this study, The aim of this qualitative study was to investigate the effect of residential and itinerant education, as well as local social welfare services on the social adaptation behavior and self-efficiency of disabled students. To this end, a preliminary investigation, program execution, and post-examination was conducted on 5 disabled students during a period of 6 months from March 6^th of 2018 to September 5^th of the same year. The results of the study is as follows. First, residential and itinerant education as well as local social welfare services appear to be closely related to the social adaptation behavior of the disabled students, especially in terms of social cognition, interpersonal relations, social adaptation, and vocational function. Second, participating in local social welfare services has been proven to improve the self-efficiency of the subjects, leading to increased self-confidence and trust in their own abilities. As the result of this study was positively accepted by the residential educators, local social welfare service researchers, disabled center workers, volunteer workers, and family members of the students, it proposes a practical implication for creating more diverse social adaptation behavior improvement programs by connecting residential and itinerant education with local social welfare services.

• Korea journal of population studies
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• v.23 no.2
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• pp.167-187
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• 2000

The rates and numbers of elderly suicide in Korea have been increased during 1985-1998. This indicates the seriousness of the problems which the elderly are faced with. So many late-life problems may push older people across the edges. Those in unbearable situations may call out fur helps, they may try to cope with various ways, or they may commit suicides. Because it is widely believed that suicide among the elderly can be understood as a personal solution or alternative to late-life problems in old age, the elderly\`s suicides seem to be an appropriate indicator in estimating seriousness of late-life problems. A comparison of the history of suicide research with other populations shows that the several late-life problems have been found with placing an individual elder at risks for increasing suicidal behaviors Research has identified such problems as financial insecurity, retirement, loss of social roles, physical illness, lack of social supports, and loneliness as the problems that increase the incidence of suicidal behavior. Though it is difficult far us to explain and understand the phenomenon of the elderly\`s suicide because of its complexity, we need to ascertain problems and social conditions behind suicides and also to prepare for some appropriate policy-tasks in light of social welfare for the aged, through examining the phenomenon. For explaining the elderly\`s suicide, the theoretical orientations are based on sociological perspectives in the paper. From the standpoints of social integration theory and exchange theory, this study is to examine the relationship between late-life problems and suicide. These two may have been fruitfully employed in conjunction with each other. Finally, this study would identify urgent late-life problems related with the elderly\`s suicide and suggest the relevant policies for Korean elders. Sometime in the near future, the government should be required to provide social welfare programs for the elderly, particularly for those at risk for increasing suicidal behaviors.

• Journal of the Korean Society of Radiology
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• v.12 no.1
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• pp.53-64
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• 2018

Using the AUDIT-K (Korean versions of alcohol use disorders identification test), it was able to select a large number of potential danger drinkers who routinely live. There were no statistically significant differences in age, religion, marital status, occupation, family history of alcohol drinking, age at onset of alcohol use, smoking, and BMI (body mass index). However, only education and drinking periods were statistically significant. These results are consistent with the previous study, which suggests that alcohol consumption is higher among men who are educated. The level of education also suggests that there is a need to look at the differences depending on what you learned and how. Alcohol consumption by education also shows different results. Also, drinking at a young age will lead to a longer drinking period, which is consistent with previous studies on the age at onset of drinking. In this study, drinking period was the most important factor of alcohol use disorder and it is considered that measures and education of national government system which can delay drinking age as much as possible is needed as a method to shorten drinking period.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.8 no.2
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• pp.164-171
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• 2005

Purpose: The aim of this study was to evaluate the clinical characteristics, endoscopic findings and risk factors related to the upper gastrointestinal bleeding (UGIB) seen in full-term infants. Methods: A clinical analysis for 9 cases with UGIB confirmed by endoscopy was carried out retrospectively. Patients were admitted to the Department of Pediatrics, Eulji Hospital, from January to December 2003. Results: UGIB from gastric or duodenal mucosal lesions has been seen in 0.13% in newborns infants. All patients were full-term AGA neonates without asphyxic findings at birth. Hematemesis, melena or recurrent vomiting developed within $4.4{\pm}3.8days$ after birth. Vital sign and laboratory test was normal on admission. Endoscopic findings showed hemorrhagic gastritis in 6 cases and peptic ulcers in 3 cases. All patients were successfully managed by medical treatment for $18.6{\pm}5.0days$. On treatment, clinical symptoms improved within $0.9{\pm}0.3days$. Follow-up endoscopy was not performed because there was no recurrence of symptoms in all patients. Case mothers had no history of gastritis, ulcer or anti-ulcer medications before and during pregnancy. Conclusion: If the healthy full-term infants express UGIB within a few days after birth, it is necessary to take careful history of family, mother and delivery process and to practice endoscopy for mucosal lesions of the patients. A follow-up endoscopy dose not seem to be necessary if the infant is clinically well.

• Pediatric Infection and Vaccine
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• v.6 no.1
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• pp.101-106
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• 1999

Purpose : Tuberculosis, a major public health problem, is an important cause of childhood infectious diseases. To decrease the tuberculosis morbidity rate, BCG vaccination and chemoprophylaxis are performed. Recently 2TU PPD skin test was introduced as a diagnostic method for tuberculous infection. We studied the positive conversion rate of 2TU PPD test after percutaneous multiple puncture BCG vaccination. Methods : Four hundred seventy six infants from well baby clinic of Samsung Cheil Hospital were enrolled. They were immunized with percutaneous multiple puncture technique BCG(Japan BCG laboratory, Japan) at 1 month of age. Approximately 6 months later, tuberculin skin test using RT23 2TU PPD was performed. Induration size, family history of tuberculosis and number of BCG scars were evaluated. Induration greater than or equal to 5mm was defined as positive conversion. Results : Among 476 infants, 248(52.1%) were male and 228(47.9%) were female. PPD skin tests were performed $6.2{\pm}0.5$($mean{\pm}S.D.$) months after BCG vaccination. Mean induration size was $7.3{\pm}3.2mm$ and positive conversion rate was 85.5%. Total number of BCG scars was $15.5{\pm}3.2$. Conclusion : The seroconversion rate by 2TU PPD test after percutaneous multiple puncture BCG vaccination was high. But, more comparative studies with various age groups may be needed for 2TU PPD test used as diagnostic method of tuberculosis in the hospitals.

• Journal of Preventive Medicine and Public Health
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• v.20 no.2 s.22
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• pp.322-330
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• 1987

The objectives of this study were to examine the changes of birth weight and relationship of birth weight with maternal age and parity. The study population included 13,634 single live births out of 14,346 births delivered at a general hospital in Busan between January 1, 1977 and December 31, 1956. Data were obtained from the delivery record. In 1979 the mean birth weight of male was 3,074 gm and that of female was 2,985 gm. In 1986 birth weight of male was increased to 3,266 gm and that of female to 3,210 gm. Low birth weight ($\leq$2,500 gm) incidence rate was 7.2% in 1977 and it was increased gradually to 10.4% in 1980 but decreased thereafter to 6.5% in 1986. Incidence rate of overweight infant (4,001 gm $\leq$) was 3.9% for 10 years and it ranged from 2.9% to 4.6% but no particular changing pattern was observed. The percentage of mothers who had history of induced abortion was decreased from 51.6% in 1979 to 45.1% in 1986. Also, stillbirth rate was decreased from 2.6% in 1977 to 1.5% in 1986. The proportion of the first and second births was increased from 55.4% in 1977 to 96.0% in 1986 and the proportion of mothers of 25-34 years increased from 72.1% in 1977 to 84.7% in 1986. The incidence rates of low birth weight and over weight infant are lower in the first and second births of 25-34 years old mothers than other parities and age groups. Increased mean birth weight and decreased low birht weight incidence rate indicate that the health status of newborn infants has been improved and substantial portion of these changes can be attributed to increase in family planning practice rate and delayed marriage. There is no evidence, however, for increasing incidence rate of overweight infant.

• Korean Journal of Child Studies
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• v.7 no.2
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• pp.1-15
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• 1986

Korea is a rapidly industrializing nation. As a consequence, more mothers are working outside the home. This trend is likely to continue into the future and raises the problem of infant-toddler care during the mother's working hours. Considering that Korea is making such rapid economic advances, quality care for children of working mothers Is not only desirable but affordable as well. Variety in options for child care is recommended by Beck (1982). Some of the alternatives in child care have been discussed elsewhere (KWDI, 1984). This paper, thus, concentrated on center-based, worksite child care. Because the human environment is the most important aspect of the center, qualified staff and a low ratio of children per staff member is Vital. Philosophy of program and its actualization ensures that the children have a worthwhile experience at the center. The physical plant houses the center and includes provision for space, materials, and equipment for staff and child use in carrying out the program. Adequate health protection is a critical factor in infant-toddler group care programs.

• Journal of Korean Home Economics Education Association
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• v.17 no.4 s.38
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• pp.1-26
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• 2005

The Purpose of this study was to investigate the eating habits, nutrition and dietary fiber intakes of middle school students from urban areas, Jinju city and rural areas, Hadong and Namhae Gun in Gyeongnam province. Data were collected by using a survey questionnaire. The result of this study are as follows: In the respects of eating habits, the eating habits of girl students ware worse than those of boy students Regardless of region and subjects, the intakes of energy, calcium, iron, riboflavin, dietary fiber were poor. In all the regions the intakes of dietary fiber was far less than $20\~25g$ of daily intakes level. Mental education should also be emphasized to form teenagers' self-identity and the sense of value. Also, the nutritionists of each school should try to focus on the composition of group meals containing fish, vegetables, Kimchi and boiled rice and cereals, not satisfying with the group meals centered on hygiene. Health and nutrition depends on the food people take, teenagers' health is the basis of their future health. The continuous study about teenagers' eating habits and dietary fiber needs to be emphasized.

• 모자간호학회지
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• v.3 no.1
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• pp.38-48
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• 1993

This study was done to suggest modification in the present hospital policy for Labour and Delivery which separates women in labour from their families. The design for study was a descriptive study. The number of subjects consisted of 82 postpartum women who had delivered within 12 hours and for whom there were no complications either for the mothers or for the newborns. Data collection was done with a structured questionnaire which was analyzed using frequencies and percentiles. The results of this study are as follows : 1. Most of subjects (90.2%) wanted their family to participate in the labour process. Husband were chosen as the primary participant(79.3%). The number of subjects who wanted their family to support them through the whole labour process (35.4%) was the highest, followed by, during labour(32.9%), as contrasted to, during delivery (1.2%). 2. Support from husband during pregnancy ranged from 55.6%-87.6% for all items. Primary support was from husband during the pregnancy. 3. The subjects wanted support from their families in labour by way of encouraging(84.1%), consolidating(81.7%), changing position(43.9%), maintaining relaxation(35.4%) and helping with respiration control (29.3%). The results showed higher support on the emotional level than the physical and informational level (26.8%). 4. The subjects answered that they expected that participation by their family during the labour process would have the effect of increasing security for the women in labour(79.3%), providing a better relationship between the family and the women in labour (57.3%) and the newborns(34.1%), and making for an easier labour courses (23.2%). 5. The priority of family members that the subjects wanted support from was, the husband, mother and mother-in-law in that order. It can be concluded that nurses help to maintain a management policy in the maternity setting which ignores the needs of the women in labour. If consideration is to be given to these subjects, future programs should include participation by the family in the labour process.