• Title/Summary/Keyword: 거대

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Peripheral Giant Cell Granuloma in a Dog (개에서 거대세포 치은종의 증례)

  • Cho, Eun-Sang;Jeon, Sung-Joo;Hong, Da-Hae;Ryu, Si-Yun;Jung, Ju-Young;Park, Bae-Keun;Son, Hwa-Young
    • Journal of Veterinary Clinics
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    • v.30 no.6
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    • pp.478-481
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    • 2013
  • A mass was detected in the oral cavity from a 18-year-old female miniature poodle dog. Grossly, the mass was soft to hard, red to purple, and $1.5{\times}1.5{\times}1cm$ in size. Histopathologically, the mass was composed of hyperplastic gingival epithelium, well-vascularized stroma, closely packed pleomorphic cells, and numerous giant cells with multiple nuclei and abundant eosinophilic cytoplasm. Immunohistochemically, tumor cells were positive for alkaline phosphatase and cytokeratin 7, but not positive for CD68 unlike in human. The mass was diagnosed to peripheral giant cell granuloma in oral cavity through typical clinical and histopathological features.

A Case of Cytomegalovirus Infection in a Neonate with Osteopetrosis (골화석증에 동반된 거대세포바이러스 감염의 1례)

  • Lee, Sang Hyun;Shin, Jeong Hee;Choi, Byung Min;Kim, Yun-Kyung
    • Pediatric Infection and Vaccine
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    • v.23 no.1
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    • pp.72-76
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    • 2016
  • Infantile osteopetrosis is a rare congenital disorder caused by abnormal bone resorption. Patients with osteopetrosis can have severe anemia, thrombocytopenia, hepatosplenomegaly, rickets, visual impairment, and deafness. Cytomegalovirus also can cause a congenital infection with anemia, thrombocytopenia, hepatosplenomegaly, and calcifications in the brain. We report a 38-day-old infant with severe hepatosplenomegaly, thrombocytopenia, hypocalcemia, and growth failure. Real time polymerase chain reaction detected cytomegalovirus in the plasma. Skeletal radiography revealed generalized bone sclerosis. He was diagnosed with osteopetrosis along with cytomegalovirus infection. Only the test for mutation of the CLCN7 gene, representing the most common and heterogeneous form of osteopetrosis, was available, and the result was negative. With supportive care and antiviral treatment, severe thrombocytopenia due to the cytomegalovirus infection almost normalized despite the possible immunosuppression caused by osteopetrosis. We present the first report of an infant who suffered from osteopetrosis and CMV infection which was successfully treated by long term antiviral agent therapy.

Giant Bone Island of the Tibia - A Case Report - (경골에 발생한 거대 골 섬 - 증례 보고 -)

  • Park, Ho-Sung;Jang, Kyu-Yun;Lee, Sang-Yong;Kim, Jung-Ryul
    • The Journal of the Korean bone and joint tumor society
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    • v.10 no.1
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    • pp.56-60
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    • 2004
  • A bone island represents a focus of mature compact bone within the cancellous bone. It can be diagnosed based on characteristic clinical and radiologic features. The lesion is typically asymptomatic with a preference for the pelvis, femur, and other long bones. On the radiologic study, the lesion appears as an ovoid, round, or oblong homogeneously dense and sclerotic focus in the cancellous bone. Characteristic feature of this lesion is radiating bony streaks, known as "thorny radiations" or "pseudopodia". Most bone islands are small, and majority of the lesions measure from 0.1 to 2.0 cm. Giant bone island, defined as a diameter greater than 2 cm, has been rarely reported in the literature. We report a case of giant bone island measured by 10${\times}$1.7${\times}$1 cm in the diaphysis of right tibia in 31-year-old man.

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Reconstruction of Distal Radius Using Ultrahigh Molecular Weight Polyethylene Liner after Excision of Giant Cell Tumor - A Case Report - (원위 요골에 발생한 거대 세포종의 일괄 절제 후 초고분자량 폴리에틸렌 삽입물을 이용한 재건술 - 증례보고 -)

  • Jeon, Dae-Geun;Song, Won-Seok;Oh, Jung-Moon
    • The Journal of the Korean bone and joint tumor society
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    • v.10 no.1
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    • pp.29-33
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    • 2004
  • A giant cell tumor (GCT) of the distal radius is not common. Curettage with bone cementation is considered as a treatment of choice but, in the case of recurrence, marked cortical disruption, or articular invasion, en bloc excision and reconstruction with proximal fibular bone graft is usual procedure. In reconstruction of en bloc resected distal radius which had recurred GCT after conservative operation, we used the ultrahigh molecular weight polyethylene (UHMWPE) liner with intramedullary rod and bone cement, because the contamination was extent in previous operation and recurrence after fibular bone graft was fearful. This article introduce our new surgical procedure.

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Localized Giant Cell Tumor of Tendon Sheath Arising from the Anterior Cruciate Ligament of the Knee - 2 Cases Report - (슬관절 전방십자인대에 발생한 국소형 건막 거대세포종 - 2례 보고 -)

  • Koo, Bon Seop;Kim, Kyung Chul;Lee, Ho Jooog
    • Journal of the Korean Arthroscopy Society
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    • v.3 no.2
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    • pp.146-149
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    • 1999
  • The localized form of a giant cell tumor of tendon sheath rarely affected the large weight-bearing joints. Only four cases of localized giant cell tumor arising in the knee joint could be found in the literatures. Physical examination of the affected knee could show pain, swelling, locking, giving way and limitation of extension, but it was difficult to differentiate from meniscal tear or cruciate ligament tear. Two cases of localized giant cell tumor of tendon sheath were incidentally found in the knees during the reconstruction of the anterior cruciate ligaments. Both tumors arising from the anterior cruciate ligament were excised arthroscopically and were confirmed to be localized giant cell tumor of tendon sheath by microscopic examination. The clinical results were good after complete excision, so we reported these cases with a review of the literatures.

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