• Tuberculosis and Respiratory Diseases
• /
• v.44 no.4
• /
• pp.815-821
• /
• 1997

Background : Salmeterol, a new ${\beta}_2$-adrenergic receptor agonist, is a long-acting bronchodilator and benefits patients with asthma who have nocturnal symptoms. We wished to assess the efficacy of inhaled salmeterol ($50{\mu}g$ bid) compared to inhaled salbutamol ($200{\mu}g$ qid) for the treatment of bronchial asthma, particularly nocturnal asthma. Method : We randomly assigned 35 patients (25 female and 10 male patients, 15 to 50 years old) to one of two treatment groups : one group received $50{\mu}g$ of salmeterol twice daily and another did $200{\mu}g$ salbutamol four times per day. And this study was performed as an open-label and the 6 weeks inhalation period. Results : Analysis of symptam score ; Day and night time symptom score showed significant difference between salmeterol and salbutamol Group (p<0.05). Number of days for additional bronchodilator requirements; The number of days and puffs for additional bronchodilator were lower in the salmeterol group in either day and night time (p<0.05). Pulmonary function test ; $FEV_1$ showed significant increase in salmeterol group compared to salbutamol group after 2 and 4 weeks inhalation period. Adverse effects ; We found no evidence of tolerance to the bronchodilating effects of salmeterol, and adverse reactions to all the treatments were infrequent and mild. Conclusion : For the management of bronchial asthma, salmeterol given twice daily is superior to salbutamol given four times daily.

• Journal of Food Hygiene and Safety
• /
• v.15 no.3
• /
• pp.186-198
• /
• 2000

The quality of the management of sanitation in food service establishments (school lunch programs, hospital patient food services, and commercial catering food services) in Korea was reviewed and evaluated, and ten strategies fur future improvement were suggested. They were: (1) An increase of qualified manpower and improvement of the professional training of the staff; (2) Obtaining special facilities exclusively for food service; (3) Improvement of facilities especially the kitchens; (4) Improvement of policy fur procuring raw materials and being assured of their quality by designing some standards and specifications for the raw materials to be purchased; (5) Production and use accurate and reliable kitchen apparatus and instruments; (6) An increase of the laboratory apparatus and instruments for inspection and evaluation of the sanitary level of raw materials and food service environments; (7) Enforced improvement of personal hygiene of the staff; (8) Use of a variety of methods in sanitary education and training; (9) Actively inspect the quality of imported foods; (10) Strengthening the research and accumulation of background data regarding sanitation management. There is a long process from the production of food to eating. The cooking process is the ultimate end of preparation of food before eating. This process sometimes increases the occurrence of food-borne diseases if we mishandle the food, even we obtained safe food. The process can also remove health hazards and reduce the risk from the hazards if we handle the food well although we have unsafe foods. This means the cooking process is a major key to preventing food-borne diseases. The concepts of hazard analysis critical control point (HACCP) should be applied and practiced in food service establishments in Korea as soon as possible.

• Clinics in Shoulder and Elbow
• /
• v.10 no.1
• /
• pp.78-83
• /
• 2007

Purpose: This study reports the clinical results of the tenodesis of long head of the Biceps brachii tendon with bioabsorbable interference screw by minimal open procedure. Materials and Methods: Ten cases of 10 patients (7 male, 3 female) were included in this study. The average age was 45.8 years old and the average period from the symptom onset to operation was 13.7 months. Average preoperative ASES score was 38.5. The causes of injury was; sports activities in 4 patients, unknown in 4 patients, industrial accident in 1 patient and traffic accident in 1 patient. The average follow up period was 12.1 months. Tenodesis with bioabsorbable interference screw by minimal open precedure was performed in all cases. Results: The ASES score improved to 87.5 at last follow up period and 6 cases had full range of motion of the shoulder. 4 cases had mild limited range of motion of the shoulder without any problem in normal daily activity. Conclusion: It was assumed that tenodesis of long head of the biceps brachii tendon with bioabsorbable interference screw by minimal open precedure was one of the good methods with good clinical results.

• Food Science and Preservation
• /
• v.18 no.2
• /
• pp.256-265
• /
• 2011

To investigate the effect of a solar salt on Kimchi fermentation, Chinese cabbages were brined with four-years aged solar salt (FS), one-year aged solar salt (OS), and purified salt (PS). The Kimchi was fermented at $7^{\circ}C$ for 33 days. The changes in pH and acidity of the Kimch brined with PS was slower than those of Kimchis brined with FS and OS. In the Kimchis with FS and OS, lactic acid bacteria (LAB) counts increased from 7.10~7.22 log CFU/mL at 0 day to 9.26~9.42 log CFU/mL at 12 days, after which counts slightly decreased to 8.04~8.75 log CFU/mL by 33 days of fermentation. The LAB counts of the kimchi with PS slowly increased from 7.24 log CFU/mL at 0 day to 8.99 log CFU/mL at 27 days, after then which counts sharply decreased to 7.92 log CFU/mL by 33 days of fermentation. Yellowness (b) color values of the kimchi with PS (59.10) was higher than the Kimchi with FS (53.68) and the Kimchi with OS (53.77). Hardness of the Kimchi with FS was more firm than the other Kimchis after 33 days storage. Sensory evaluation of the Kimchi with FS showed higher score than that of the other Kimchis.

• Journal of Digital Convergence
• /
• v.15 no.6
• /
• pp.19-27
• /
• 2017

The purpose of this study was to analyze the differences of creativity according to major of college students focusing on pre-service early childhood teachers, pre-designers and pre-engineers. The subjects were 132 four grade of university students attending K and T university in Busan, Korea. Data were analyzed with one-way MANOVA to find out the differences of creativity according to their major. Results of this study as follows: first, overall creativity was significantly higher in preliminary designers than pre-service early childhood teachers and pre-engineers. Second, the fluency of pre-service early childhood teachers and pre-designers was significantly higher than that of pre-service engineers. The abstraction was significantly higher in pre-service early childhood teachers than pre-engineers. The elaboration of pre-designers was significantly higher than that of pre-service teachers and pre-engineers. Openness was significantly higher in pre-designers than pre-engineers, and pre-engineers were significantly higher than pre-service early childhood teachers. Therefore, this study suggests that the major in creativity curriculum and program development for college students should be considered, and the results of this study will be used as basic data of the creativity education program.

• Journal of The Korean Association For Science Education
• /
• v.32 no.5
• /
• pp.823-840
• /
• 2012

The importance of teaching the nature of science (NOS) has been emphasized in the science curriculum, especially in the science curriculum for science-gifted students. Nevertheless, few studies concerning the structure and formation of students' mental model on NOS have been carried out. This study aimed to explore science-gifted students' understanding of 'fact', 'hypothesis', 'theory', 'law', and 'scientificness' by utilizing semantic network analysis. One hundred ten science-gifted middle school students who were selected by a national university participated in this study. We collected students' written responses of five items and analyzed them by the semantic network analysis(SNA) method. As a result, the core ideas of students' understanding of 'fact' were proof and reality, of 'hypothesis' were tentativeness and uncertainty, of 'theory' was proven hypothesis by experimentation, of 'law' were absoluteness and authority, and of 'scientificness' were factual evidence, verifiability, accurate and logical theoretical framework. The result of integrated semantic network illustrated that the viewpoint of science-gifted students were similar to absolutism and logical positivism (empiricism). Methodologically, this study showed that the semantic network analysis method was an useful tool for visualization of students' mental model of scientific conceptions including NOS.

• Journal of The Korean Association For Science Education
• /
• v.40 no.4
• /
• pp.359-374
• /
• 2020

This study is a complex type consisting of survey study and self-study. The former investigated elementary teachers' epistemological beliefs on convergence knowledge and teaching. As a representative of the result of survey study I, as a teacher as well as a researcher, was the participant of the self-study, which investigated my epistemological belief on convergence knowledge and teaching and my execution of convergent science teaching based on family resemblance of mathematics, science, and physical education. A set of open-ended written questionnaires was administered to 28 elementary teachers. Participating teachers considered convergent teaching as discipline-using or multi-disciplinary teaching. They also have epistemological beliefs in which they conceived convergence knowledge as aggregation of diverse disciplinary knowledge and students could get it through their own problem solving processes. As a teacher and researcher I have similar epistemological belief as the other teachers. During the self-study, I tried to apply convergence knowledge system based on the family resemblance analysis among math, science, and PE to my teaching. Inter-disciplinary approach to convergence teaching was not easy for me to conduct. Mathematical units, ratio and rate were linked to science concept of velocity so that it was effective to converge two disciplines. Moreover PE offered specific context where the concepts of math and science were connected convergently so that PE facilitated inter-disciplinary convergent teaching. The gaps between my epistemological belief and inter-disciplinary convergence knowledge based on family resemblance and the cases of how to bridge the gap by my experience were discussed.

• Proceedings of the Korean Society for Bioinformatics Conference
• /
• 2004.11a
• /
• pp.86-100
• /
• 2004

계산을 통한 단백질 상호작용 예측 기법의 중요성이 제기되면서 많은 단백질 상호 작용 예측 기법이 제안되고 있다. 하지만 이러한 기법들이 일반 사용자가 손쉽게 사용할 수 있는 서비스 형태로 제공되고 있는 경우는 드물다. 본 논문에서는 현재까지 알려진 단백질 상호작용 예측 기법 중 예측 기법의 완성도가 높고 상대적으로 예측 정확도가 높은 것으로 알려진 도메인 조합 기반 단백질 상호 작용 예측 기법을 PreSPI(Prediction System for Protein Interaction)라는 서비스 시스템으로 설계하고 구현하였다. 구현된 시스템이 제공하는 기능은 크게 도메인 조합 기반 단백질 상호 작용 예측 기법을 서비스 형태로 만들어 제공하는 기능으로 입력 단백질 쌍에 대한 상호작용 예측이 중심이 된 핵심기능과, 핵심 기능으로부터 파생되는 기능인 부가 기능, 그리고 주어진 단백질에 대한 도메인 정보검색 기능과 같이 단백질 상호작용에 관하여 연구하는 연구자에게 도움이 되는 일반적인 기능으로 구성되어 있다. 계산을 통해 단백질 상호 작용을 예측하는 시스템은 대규모계산이 요구되는 경우가 많아 좋은 성능을 갖추는 것이 중요하다. 본 논문에서 구현된 PreSPI 시스템은 서비스에 따라 적절히 그 처리를 병렬화 함으로써 시스템의 성능 향상을 도모하였고, PreSPI 가 제공하는 기능을 웹 서비스 API 로 Deploy 하여 시스템의 개방성을 지원하고 있다. 또한 인터넷 환경에서 변화되는 단백질 상호 작용 및 도메인에 관한 정보를 유연하게 반영할 수 있도록 시스템을 계층 구조로 설계하였다. 본 논문에서는 PreSPI 가 제공하는 몇 가지 대표적인 서비스에 관하여 사용자 인터페이스를 중심으로 상술함으로써 초기 PreSPI 사용자가 PreSPI 가 제공하는 서비스를 이해하고 사용하는 데에도 도움이 되도록 하였다.있어서 자각증상, 타각소견(他覺所見)과 함께 이상(異常)은 확인되지 않았으며 부작용도 없었다. 이상의 결과로부터, ‘펩타이드 음료’는 경증고혈압 혹은 경계역고혈압자(境界域高血壓者)의 혈압을, 자각증상 및 혈액${\cdot}$뇨검사에도 전혀 영향을 미치지 않고 저하시킨다고 결론지었다.이병엽을 염색하여 흰가루 병균의 균사생장과 포자형성 등을 관찰한 결과 균사가 용균되는 것을 볼 수 있었으며, 균사의 용균정도와 분생포자형성 억제 정도는 병 방제효과와 일치하는 경향을 보였다.을 의미한다. IV형은 가장 후기에 포획된 유체포유물이며, 광산 주변에 분포하는 석회암체 등의 변성퇴적암류로부터 $CO_{2}$ 성분과 다양한 성분의 유체가 공급되어 생성된 것으로 여겨진다. 정동이 발달하고 있지 않으며, 백운모를 함유하고 있는 대유페그마타이트는 변성작용에 의한 부분용융에 의해 형성된 멜트에서 결정화되었으며, 상당히 높은 압력의 환경에서 대유페그마타이트의 결정화작용 과정에서 용리한 유체의 성분이 전기석에 포획되어 있다. 이때 용리된 유체는 다양한 성분을 지니고 있었으며, 매우 낮은 공융온도와 다양한 딸결정은 포유물 내에 NaCl, KCl 이외에 적어도 $CaCl_{2},\;MgCl_{2}$와 같은 성분을 포함하고 있음을 지시한다. 유체의 용리는 적어도 $2.7{\sim}5.3$ kbar 이상의 압력과 $230{\sim}328^{\circ}C$ 이상의 온도에서 시작되었다.없었다. 결론적으로 일부 한방제와 생약제제는 육계에서 항생제를 대체하여 사용이 가능하며 특히 혈액의 성분에 유의한 영향을 미치는 것으로 사료된다. 실증연구가 필요할 것으로 사료된다.trip과 Sof-Lex disc로 얻어진 표면은 레진전색제의 사용으로 표면조도의 개선

• Journal of Science Education
• /
• v.38 no.2
• /
• pp.257-269
• /
• 2014

The purpose of this study was to analyze of high school students' metacognition and scientific attitude according to gender and academic track. Also it was to investigate relationship between metacognition and scientific attitude. Data were gathered through questionnaires of 220 high school students. In the result of analysis on metacognition according to gender, the mean of male group was higher than the score of female group. The result of t-test wasn't showed statistically significant difference of two groups. In analysis on metacognition according to academic track, the score of science track students were higher than its liberal art track. And the difference between two groups was significant. The result of analysis on scientific attitude according to gender showed no difference between male group and female group. But there was significant difference between two groups in analysis on scientific attitude according to academic track. Also there was high correlation between sub-elements of metacognition and scientific attitude. The result of multiple regression analysis revealed the influence of moniter, regulation, criticism and openness. The results of this study can be utilized as basic data to develop teaching-learning strategy for cultivating high school students' metacognition and scientific attitude. Follow-up studies are needed for analyzing the relations of factors on science learning.

• The Journal of Korean Association of Computer Education
• /
• v.13 no.2
• /
• pp.1-14
• /
• 2010

Previous researches on the improvement of logical thinking in Informatics subject have used general logical thinking test and only limited improvement of logical thinking by programming learning result. In this study, the operational definition of the logical thinking in problem-solving process on Informatics education is different from the general logical thinking and the logical thinking of the other subjects. Firstly, we suggested the operational definition of components of logical thinking using the open questionnaire by expert and research team discussion. Also, we suggested the relationship between the operational definition and contents of the 'problem-solving methods and procedure' section in secondary Informatics subject. Finally, this study developed the evaluation contents based on the operational definition of components of logical thinking. The components of logical thinking which was required in problem-solving process on Informatics subject were ordering reasoning, propositional logic, controlling variables, combinatorial logic, proportional reasoning. We suggested the relationship between operational definition and problem-solving process and assessment of logical thinking in problem-solving process on Informatics subject. This paper will give meaningful insight to supply the guideline of the teaching strategy and evaluation methods for improving the logical thinking in Informatics education.