• Proceedings of the Korean Journal of Food and Nutrition Conference
• /
• 2000.12a
• /
• pp.54.2-54
• /
• 2000

일반식용의 참쑥과 강화지역 특산물인 강화약쑥의 첨가급식이 체성장 및 성분에 미치는 영향을 관찰하고자 89g 내외의 흰쥐(Sprague Dawley) 24두를 3개 동물군(대조군, 참쑥군 및 약쑥군)으로 나누어 4주간 해당 실험식이(대조식이, 5%참쑥식이 및 5%약쑥식이)로 급식하였다. 쑥의 일반영양 성분 함량은 참쑥 중 조단백질과 조회분은 약쑥보다 약 2%이상 높았으나 반대로 조지방은 약 2%낮았다. 또한 약쑥 중 칼슘은 참쑥보다 5.3배 높았으나 반대로 참쑥 중 망간, 아연, 철, 마그네슘은 2.8∼2.3배, 비타민A는 2.9배가 높았다. 체중 증가율과 식이효율은 참쑥군 과 약쑥군이 모두 대조군과 비슷하였다. 혈청 중 총단백질, albumin, 요소질소, creatinine, 뇨산, 총cholesterol, HDL-C, LDL-C, 당 함량과 amylase와 transaminase(GOT, GPT)의 활성이 참쑥군과 약쑥군 간에 유의성 있는 차이를 나타내지는 않았으나 LDH의 활성은 약쑥군이 대조군과 참쑥군에 비하여 감소(p<0.05)하였다.

• Korean Journal of Plant Taxonomy
• /
• v.42 no.2
• /
• pp.161-166
• /
• 2012

Aiming to determine the taxonomic identity of Gang-hwa-yak-ssuk as a cultivated plant, this study analyzes ITS sequences and compares their external morphologies with the genus Artemisia, which have a similar external morphology. Thus far, we have considered A. indica as the original plant of Gang-hwa-yak-ssuk, but Gang-hwa-yak-ssuk is better grouped with A. argyi, not A. indica, for the following reasons: Gang-hwa-yak-ssuk has the same characteristics as A. argyi in terms of the natural habitat, in that it is 1-bipinnately cleft or parted in the external morphology of its leaves, and because the white glandular trichome is distributed on the adaxial surface. This is in addition to the result of ITS sequence analysis. Therefore, we can define Gang-hwa-yak-ssuk as a cultivated plant that originates from A. argyi and not A. indica.

• The Korean Journal of Food And Nutrition
• /
• v.14 no.5
• /
• pp.411-417
• /
• 2001

This study was designed to observe the effects of edible mugwort and medicinal mugwort ( Ganghwa medicinal mugwort) on blood components of rats. Eighteen young rats of Sprague Dawley strain that weighted 84${\pm}$9g, were used in this study. They were fed on the basal diet(control diet). 5% edible mugwort powder(EM diet) and 5% medicinal mugwort(MM diet) for 4 weeks respectively. In proximate composition of mugworts, crude protein and crude ash contents of EM were 2% higher than those of MM. Mn, Zn and vitamin A contents of EM were 3 times higher than those of MM, but in Ca content, MM was 5 times higher than that of EM. The contents of albumin and the activity of ALT, AP amylase and CK in serum were significantly increased, but the activity of AST was significantly lowered in EM and MM diet groups. The contents of TG and the activity of LDH were towered in EM diet group and MM diet group resulted in decrease of glucose content and increase of TP content.

• Korean Journal of Agricultural and Forest Meteorology
• /
• v.14 no.2
• /
• pp.71-78
• /
• 2012

Eupatilin, one of representative medical components of mugwort, can be efficiently extracted from the 'Gangwha Sajabalssuk'. The Eupatilin content may depend on environmental factors such as soil and regional climate in addition to a genetic factor and Gangwha region has a profitable environmental condition for the mugwort growth. In this study, the climatological characteristics of Gangwha was analyzed in order to find the environmental condition of mugwort containing high Eupatilin in term of atmospheric, oceanographic and land variables. The climate of Gangwha is characterized by the relatively low daily temperature and large diurnal variation with plenty of solar radiation, long sunshine duration and less cloudiness. According to our correlation analysis, the long sunshine duration and the large diurnal temperature variation are highly correlated with the Eupatilin contents. The result implies that Gangwha has the favorable conditions for the cultivation and the habitat of the high-Eupatilin concentrated mugwort. Because of the sea surrounding Gangwha Island with low salinity and moderate wind, the salt contained in sea breeze is relatively low compared to other regions. Furthermore, Gangwha has clean atmospheric environment compared to other regions because the concentrations of toxic gases harmful to crop growth such as nitrogen dioxide ($NO_2$), sulfite gas ($SO_2$) and fine dust (PM-10) are lower in the air. The ozone ($O_3$) concentration is moderate and within the level of natural production. It is also found that moderately coarse texture or fine loamy soils known as good for water drainage and for the growth and cultivation of the 'Gangwha-mugwort' are distributed throughout the areas around mountainous districts in Gangwha, coinciding with those of mugwort habitat.

• Journal of Applied Biological Chemistry
• /
• v.63 no.4
• /
• pp.439-442
• /
• 2020

In vitro antioxidant and anticoagulant activities of 50% ethanolic extract from Ganghwa medicinal mugwort (Artemisia princeps Pampanini) were investigated. The polyphenol and flavonoid contents of the mugwort extract were 106.9±3.3 and 34.1±0.4 mg/g-extract, respectively. The mugwort extract possessed a potent scavenging activity against radicals and nitrite, reducing power, and lipid peroxidation inhibition activity in a concentration-dependent manner. Also the mugwort extract delayed the plasma coagulation time through the inhibition of common coagulation pathway in a dose-dependent manner.

• KOREAN JOURNAL OF CROP SCIENCE
• /
• v.49 no.spc1
• /
• pp.169-175
• /
• 2004

동의보감에 수재되어 있는 약쑥은 식용뿐만이 아니고 한방에서는 출혈 및 지혈약으로 자궁출혈, 임신중의 출혈, 코피지혈 등에 효과가 크다고 알려져 왔다. 또한 부인병과 건위, 설사치료와 항암활성, HeLa cell에 대한 억제작용도 보고되어 있다. MeOH엑스가 HCl-EtOH유발법, $1\%$ 암모니아 수용액 유발법, HCl-aspirin 유발법등에 의하여 유발된 위 손상에 대하여 강한 억제 작용을 나타내고 있는데 이는 flavonoid의 일종인 eupatilin으로 확인된 바 있다. 이 물질이 5-lipoxygenase inhibitor ($ID_{50}=14{\times}16^{-6}M$) 작용과 prosta glandin synthase의 활성을 약간 억제한다고 보고되었다. 약쑥의 eupatilin과 jaceosidin을 분리하여 그 화학구조를 구명하였다. 이를 지표물질로 하여 HPLC 분석조건과 HPLC용 검체의 조제, 표준검량선을 작성하였다. 강화사자발쑥 100 g의 잎에는 eupatilin은 240 mg, jaceosidin은 10 mg함유되어 있고 싸주아리쑥에는 eupatilin은 330 mg, jaceosidin은 123 mg 함유되어 있음이 확인되었다.

• Proceedings of the Korean Society of Crop Science Conference
• /
• 2007.11a
• /
• pp.259.2-259.2
• /
• 2007

• 한국약용작물학회:학술대회논문집
• /
• 2008.05a
• /
• pp.188-189
• /
• 2008

• 한국약용작물학회:학술대회논문집
• /
• 2008.05a
• /
• pp.215-215
• /
• 2008

• KOREAN JOURNAL OF CROP SCIENCE
• /
• v.51 no.spc1
• /
• pp.220-223
• /
• 2006

Mugwort, Artemisia princeps Pampanini, has been used as natural medicine traditionally in the far east countries including Korea. This study was performed with the object of provoding basic data an leaf quality improvement in mugwort. The 210 mugwort were collected in 48 locations from 2004 to 2006, leaves of 210 genotypes collected were analyzed for eupatilin, jaceosidin and sesamin content. The eupatilin content was averaged to 43.8mg (100 g leaves) and ranged from 0 to 228.0 mg. The average jaceosidin and sesamin contents were 12.8 mg and 3.58 mg and the ranges of those were 0 to 73.8 mg and 0 to 6.56 mg, respectively. The eupatilin content of mugwort harvested in the western region was higher compared with those harvested in the resemble altitude of the southern and eastern of Korea.