• Journal of Service Research and Studies
• /
• v.3 no.2
• /
• pp.45-52
• /
• 2013

With the development of information and communication technology, the Internet is more important in the social and economic influence rapidly, and it is no different in the field of health care. As health information on the Internet increasing, the availabilities of health information from the Internet becomes more important with health care professionals and information specialists. the quality of health information on the Internet are continually being presented without any guarantee or judge on the quality. It is needed to provide the right to use of qualified health information through Internet. HONCODE has been established and managed by HON (Health On the Net) Foundation. In this paper, Web sites of thyroid cancer Information are evaluated using HONCODE. They provide domestic medical information on the Internet. Through this, more accuracy and evaluated information could be provided on the Internet about the thyroid cancer.

• Journal of the Korean Society of Radiology
• /
• v.11 no.1
• /
• pp.19-25
• /
• 2017

In this study, in order to analyze the general awareness of the nuclear power according to the controversy of thyroid cancer around nuclear plant, we investigated risks, preference and economics regarding type of power, and awareness of pre-post nucl ear power targeting the Busan Metropolitan residents. As a result, there has been a change in people's awareness of nuclear power as a result of the controversy thyroid cancer around nuclear plant. Especially, there was the greatest increase in the risk factors compared to before the event(p<0.05). Negative awareness of nuclear risk was shown to be expressed differently accor ding to the difference between groups. It is thought that this is due to the different prior experience of each individuals or obtained information through the interaction with others rather than on scientific and objective grounds. In order to establish a nuclear power policy considering the level of the people in the future, it seems that the efforts to understand the attitudes and opinions of people about nuclear power and above all, a scientific trust in nuclear power should be guaranteed.

• The Monthly Diabetes
• /
• s.253
• /
• pp.62-63
• /
• 2010

대표적인 서구암으로 알려진 유방암이 최근 들어 무서운 속도로 증가하고 있다. '2009년 보건복지부 국가암등록' 통계에 따르면 유방암은 우리나라 여성암 중 갑상선 암 다음으로 가장 많이 거리는 암인 것으로 밝혀졌다.

• The Korean Journal of Nuclear Medicine
• /
• v.26 no.1
• /
• pp.147-150
• /
• 1992

In general, hot nodules on techetium scan are regarded as benign tumors, and usually no further work up for malignancy is indicated, if they are truly autonomous. The authors experienced two cases of thyroid carcinoma presenting as hot nodule on technetium-99m pertechnetate thyroid scintigraphy. One case with papillary carcinoma, and other case with follicular carcinoma are presented in addition to a review of the literature.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.19 no.11
• /
• pp.370-379
• /
• 2018

This study was conducted 1) to investigate the effects of treatment and other factors on the quality of life of thyroid cancer surgical patients and 2) to provide fundamental data for development of an intervention and symptom management program to improve the quality of life of those patients. A total of 76 patients who were diagnosed with thyroid cancer and underwent thyroidectomy from July 2013 to December 2014 participated in this study. To investigate the factors affecting quality of life, a t-test and ANOVA analyses were conducted, after which multiple regression analysis was performed. The results were statistically significant between preoperative and one month after surgery of sex, cancer history, fatigue, and quality of life until 3 months after surgery of stage, cancer history, anxiety, and pain. Multiple regression analysis showed that the most influential factors affecting the quality of life were depression and fatigue at one month prior to and after surgery and anxiety at three months after surgery, while no factors were found to be influential at six months after surgery. Overall, the results of this study suggested that it is imperative to manage depression and fatigue one month prior to and after surgery to reduce the physical and psychological pain experienced by thyroid cancer patients. Moreover, three months after the surgery, anxiety should be closely monitored and controlled to improve the quality of life of the patients. This approach is expected to reduce the burden on the health care system and social costs, which will positively affect public health.

• Journal of the Korean Society of Radiology
• /
• v.10 no.8
• /
• pp.583-590
• /
• 2016

The subjects in this study are the residents of Busan, analyzing the perception gap between the residents adjacent to the nuclear plant and living in town, about the lawsuit of thyroid cancer damage nearby the nuclear plant, to distinguish the citizen's acceptance level about the nuclear power. 551 people(269 people adjacent to nuclear plant, 282 people in town) were face-to-face surveyed and the result showed that people's perceptions of the nuclear power has changed after the thyroid cancer damage lawsuit. In the case of the residents adjacent to the nuclear plant, it became clear that the negative perception of nuclear power became stronger due to increasing distrust and anxiety about nuclear power after the lawsuit of thyroid cancer damage nearby the nuclear plant. On the other hand, people living in town showed their positive perceptions of nuclear power despite the thyroid cancer damage lawsuit. However, two-sided perception was shown compared to the acceptance of nuclear power, since the safety and reliability of the nuclear power was analyzed as negative perception. Therefore, for the constant increased use of nuclear power in the future, national understanding and credibility, including the communication with the nation or the residents in the neighboring area of nuclear power plant, will be necessary.

• 대한핵의학회:학술대회논문집
• /
• 2001.11a
• /
• pp.45.1-45.1
• /
• 2001

• Korean Journal of Head & Neck Oncology
• /
• v.9 no.1
• /
• pp.25-32
• /
• 1993

The nodular hyperplasia of the thyroid is a common thyriod disease. Nodular hyperplasia does rarely progress to thyroid cancer. The differentiation of a nodular hyperplasia from a neoplasm may be simple or difficult, both clinically and anatomically. The papillary carcinoma of the thyroid is the most common type of thyroid malignancies. There were few studies about cytogenetic observation in thyroid cancer. But only one case of banding observation in nodular hyperplasia have been reported. In order to compare the chromosomal changes in the thyroid cancer and the noncancerous thyroid disease, we performed cytogenetic analysis in two papillary carcinoma and two nodular hyperplasia after cell culture. The chromosomal pattern of the nodular hyperplasia found was very heterogenous but no clonal abnormaly in both cases was observed. Case I : A modal chromosomal number was in 42-46 range. Chromosome 8, 19, 21. 22 were commonly lost. 9 structural anomalities among 51 analysed cells were observed but they were not clonal. Case II: A modal chromosomal number was 43. Chromosome 17 and 19 were commonly lossed. Common cytogenetic characters of this two nodular hyperplasia are hypodiploidity and very heterogenous chromosomal pattern. The result about the papillary carcinoma are as follow. In one case some numerical and structural chromosomal changes were observed. But they were not clonal abnormality. In another case the chromosomal pattern found was very heterogenous with a clonal abnormality of del(11)(q23). The modal number was 46. The del(11)(q23) a chromosomal change in papillary carcinoma of the thyroid have previously been reported(Eva Olah et al. 1989). We suggest that 11q deletion may be important role to pathogenesis of papillary carcinoma of the thyroid. According to this results, we could not find out specific differences about chromosomal changes and any relationship between the papillary carcinoma and the nodular hyperplasia.

• Nuclear Medicine and Molecular Imaging
• /
• v.41 no.5
• /
• pp.343-349
• /
• 2007

Radioiodide transport has been extensively and successfully used in the evaluation and management of thyroid disease. The molecular characterization of the sodium/iodide symporter (NIS) and cloning of the NIS gene has led to the recent expansion of the use of radioiodide to cancers of the breast and other nonthyroidal tissues exogenously transduced with the NIS gene. More recently, discoveries regarding the functional analysis and regulatory processes of the NIS molecule are opening up exciting opportunities for new research and applications for NIS and radio iodide. The success of NIS based cancer therapy is dependent on achievement of maximal radioiodide transport sufficient to allow delivery of effective radiation doses. This in turn relies on high transcription rates of the NIS gene. However, newer discoveries indicate that nontranscriptional processes that regulate NIS trafficking to cell membrane are also critical determinants of radioiodide uptake. In this review, molecular mechanisms that underlie regulation of NIS transcription and stimuli that augment membrane trafficking and functional activation of NIS molecules will be discussed. A better understanding of how the expression and cell surface targeting of NIS proteins is controlled will hopefully aid in optimizing NIS gene based cancer treatment as well as NIS based reporter-gene imaging strategies.

• International journal of thyroidology
• /
• v.11 no.2
• /
• pp.61-70
• /
• 2018

Tyrosine kinase inhibitors (TKIs) are widely used for the treatment of advanced radioiodine-refractory thyroid cancer. Although the previous studies including large-scale randomized controlled trials have demonstrated the effects of TKIs in advanced thyroid cancers, it has been found that most patients experienced adverse events (AEs). Unlike other cancers, even patients with advanced thyroid cancers are often asymptomatic. Rather, TKI use can make patients suffer adverse events. Therefore, the use of TKI should be decided after the full consideration of AEs as well as its efficacies. While using TKI, AEs should be monitored, evaluated, and managed appropriately, if AEs develop. In this review, the occurrence, evaluation, and management of AEs of sorafenib, lenvatinib, and vandetanib will be described, which TKIs are most commonly used for the treatment of advanced thyroid cancer. Some suggestions for the management of AEs in the real life are also provided.