• Clinical and Experimental Pediatrics
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• v.45 no.10
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• pp.1199-1203
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• 2002

Purpose : The study aimed to evaluate the efficacy of auditory brainstem response(ABR) as a screening tool in children with speech and language disorders. Methods : Between January 1, 1999 and December 31, 2001, 139 patients with chief complaints of speech and language delay were recruited from the pediatric neurology clinic, Kyungpook National University Hospital, Daegu, Korea. They had ABR on entry and the clinical data were then analyzed. Results : Fifteen out of 139 cases(10.8%) showed abnormal findings; seven had pervasive developmental disorders, four had developmental language disorders, and four were noted to have other conditions. Among them, seven cases were noted to have conductive hearing loss and eight had sensoryneuronal hearing loss. We also evaluated the normal values in children at the ages of 18 months to seven years. The mean latency of wave I and V were $1.40{\pm}0.13$ and $5.57{\pm}0.26$ respectively. Interpeak latency of I-V was $4.18{\pm}0.24$. Conclusion : Based on these findings, ABR has proved to be a highly sensitive and specific index of hearing impairment. It should be used as a screening tool in children with speech and language disorders.

• The Journal of Korean Academy of Sensory Integration
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• v.9 no.2
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• pp.15-28
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• 2011

Objective : The purpose of the study was to investigate effects of sensory integration therapy on self-regulation capacities of children with cerebral palsy. Methods : Subjects of this study were four years old girl and six years old boy, living in P city. Both were diagnosed as diplegia. Research design used in this study is ABA' design for a single-subject research. The experimental period was 12 weeks with 22 sessions of treatment. It was divided into three phase: 6 sessions for baseline phase (A), 14 sessions for treatment phase (B), 2 sessions for baseline phase (A'). There was no treatment on the baseline phases, and sensory integration therapy focused vestibular and proprioceptive stimuli was conducted on the treatment phase. At each session, subjects' behaviors has been recorded with a Digital Camera for 10 minutes and then the occurrence frequency of problematic behavior was identified based on the operational definition of it. Results : In comparison with the baseline phase (A), the occurrence frequency was reduced during the treatment phase for three types of problematic behavior associated with the self-regulatory capacities. The tendency of reducement was maintained during baseline phase (A'). Conclusion : Based on the result, it was implied that sensory integration therapy has a positive effect on the self-regulation capacities in children with cerebral palsy.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 1998.11a
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• pp.213-217
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• 1998

본 연구에서는 고감성 의류상품 개발을 위한 기초 자료들 제공하기 위해 폴리에스테르 직물에 대한 감각·감성을 1, 2단계로 나누어 분석하였다. 1단계에서는 얇은 여성 외의용 폴리에스테르 24종을 사용하여 감성측정에 영향을 미치는 제요인에 대해 검토하였다. 즉, 감각·감성측정시 기준직물과 그 평가치 제시 유무, 제시방법(blind/ open eye test), 환경과 직물 종류에 따른 효과를 조사하였다. 2단계에서는 1단계의 결과를 토대로 폴리에스테르 10종을 이용하여 환경에 따른 감각·감성과 물성 변인간 관계를 규명하였다. 1. 1단계의 연구결과, 기준직물 제시유무에 따라 감각·감성에 부분적으로 차이가 있었다. 유색직물의 평가시에는 blind/open eye test에 따라서 몇가지 평가용어를 제외하면 전반적으로 직물의 색에 따른 감각.감성에 유의차가 없었다. 2. 감각용어에 대한 요인분석 결과, 표준환경에서 1요인으로 두께, 무게(두껍다. 폭신폭신하다. 가볍다), 2요인으로 표면특성(매끄럽다. 부드럽다. 오돌도돌하다.), 3요인으로 강연성(뻣뻣하다. 보송보송하다)이 추출되었다. 고온다습환경에서도 유사한 결과였다. 3. 환경 효과는 고온다습환경에서 표준환경에서보다 더 눅눅하게, 덜 보송보송하게, 덜 차게 감지하는 것으로 나타났다. 직물의 효과는 모든 용어에서, 환경과 직물의 상호작용효과는 (차다. 보송보송하다. 뻣뻣하다. 하늘하늘하다. 촉감이 졸다.)에서 유의차가 나타났다. 4. 여러 통계기법에 의해 감각·감성 및 물성변인을 분석하여 종합한 결과, 표준환경에서 감성과 관련높은 용어는 (하늘하늘하다), 물성은 SMD로, 고온다습환경에서 감성과 관련 높은 용어는 (보송보송하다), 물성은 Contact area로 밝혀졌다. 폴리에스테르 직물에 대한 감성의 감각구조는 환경에 따라 상이하며 관련 물성 중 표면접촉특성은 환경에 관계없이 가장 중요한 변인으로 작용한다고 할 수 있다.었으며 또한 essential oil에서는 성별 차이가 없는데 반해 페르몬 향의 경우 성별의 차이를 나타내었다.. 방법을 타액과 혈청내 testosterone 농도 측정에 응용하여 RIA의 결과와 비교하여 본 바 상관관계가 타액에서 r=0.969, 혈청에서 r=0.990으로 두 결과가 잘 일치하였다. 본 실험에서 측정된 한국인 여성의 타액내 testosterone농도는 107.7$\pm$12.0 pmol／l이었고, 남성의 타액내 농도는 274.2$\pm$22.1 pmol／l이었다. 이상의 결과로 보아 본 연구에서 정립된 EIA 방법은 RIA를 대신하여 소규모의 실험실에서도 활용할 수 있을 것으로 사려된다.또한 상실기 이후 배아에서 합성되며, 발생시기에 따라 그 영향이 다르고 팽창과 부화에 관여하는 것으로 사료된다. 더욱이, 조선의 ${\ulcorner}$구성교육${\lrcorner}$이 조선총독부의 관리하에서 실행되었다는 것을, 당시의 사범학교를 중심으로 한 교육조직을 기술한 문헌에 의해 규명시켰다.nd of letter design which represents -natural objects and was popular at the time of Yukjo Dynasty, and there are some documents of that period left both in Japan and Korea. "Hyojedo" in Korea is supposed to have been influenced by the letter design. Asite- is also considered to have been "Japanese Letter Jobcheso." Therefore, the purpose of this study is to look into the origin of the letter design

• The Journal of Korean Academy of Sensory Integration
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• v.11 no.2
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• pp.1-11
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• 2013

Objective : The purpose of this study is to verify the effect of sensory integrative intervention on postural control and occupational performance (play) of the preschool child with postural disorder. Methods : Subject of this study was a 5 years and 8 month old boy. The subject underwent a sensory integration (SI) treatment which was part of the SI clinic course administered by the Korean Sensory Integration Society, in 2012. The treatment goal and treatment plan had established based on the evaluation results. Treatment was done with 11 sessions, the treatment activities and the adaptive responses of the subject were measured as outcome of the SI treatment. The goal of sessions were measured as Goal Attainment Scale, and re-evaluation was done on December in 2012. Results : During SI treatment, the subject was improved the stability of proximal body parts so that maintained Supine-Flexion Posture more than 20 seconds. He also showed increased attention span continuously about 1 activity on physical play. Conclusion : According to the results of this study, it was verified that sensory integrative intervention has positive effective on postural control and occupational performance (play) of the preschooler with postural disorder.

• The Journal of Korean Academy of Sensory Integration
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• v.7 no.1
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• pp.37-46
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• 2009

Background : Theory of Sensory Integration (SI) was initially developed with an effort to understand children's behavior by Jean Ayres and has been evolved with extensive research by occupational therapist practitioners and researchers since in the latter of the 20 century. With extension of recognition to SI, various professions begin to refer their clients who are children with sensory integration dysfunction. Upon those referrals, occupational therapists normally use Short Sensory Profile (SSP) to screen and decide whether SI therapeutic intervention is needed or not. Objective : Purpose of this study is (1) to examine any difference between different age groups and genders for children who are seven to nine years old; (2) to compare the score results of those Korean children with the original Standard which is established for American children: and (3) to compare tendency of response for each item between children with- and without SI dysfunction. This study was intended to validate test items of the SSP and determine whether the original standard of SSP is applicable for Korean children. Method : 155 students (81 for male, 74 for female) underwent SI evaluation using the Korean-translated SSP. 52 student (22 for male, 30 for female) were 7 years old, 54 students (32 for male, 22 for female) were 8 years old, 49 students (27for male, 22 for female) were 9 years old. Results : There is no significant difference of SSP score by neither age nor gender. In comparison the average score and sensory integrative disorder with the American Standard, there is significant difference on score of sub-item and total score. For six items, there is no significant difference on the tendency of response between children with- and without SI dysfunction. Conclusions : It is concluded that the original standard is suitable for Korean children aged seven to nine. The six test items that children without SI dysfunction shown similar tendency to respond are questionable to be appropriate as screening test item. It is suggested to proceed to do further item analysis study and extend the study to broad age groups, so develop the most appropriate Standard of SSP for Korean children.

• Progress in Medical Physics
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• v.17 no.3
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• pp.159-166
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• 2006

The nonlinearity of hemodynamic response in the somatosensory cortex was investigated with vibrotactile stimulation. The stimuli consisted of a train of 25 Hz, each tasting five different duration periods, 2 s, 4 s, 8 s 12 s, or 16 s with 20 sec periods of no vibration in a pseudo-random order. In order to understand the linearity on the change of stimulus duration for somatosensory cortex, two different tests- checking the linearity of system and finding the impulse response function from gamma-variate function were applied to analyze the hemodynamic response functions. They have produced nearly same results. The BOLD response in the somatosensory cortex Is nonlinear for stimuli of less than 8 seconds, but nearly linear for stimuli greater than 8 seconds. The amplitude, area, TTP, and FWHM as functions of the stimulus duration were calculated and showed a significant downward trend with Increasing stimulus duration for the amplitude and the area. It supports the ranges of nonlinearity are less than 8 seconds.

• Journal of the HCI Society of Korea
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• v.2 no.1
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• pp.41-47
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• 2007

This study aims to empirically examine the effect of feedback on attention recovery. The role of feedback has been proven to be positive in particular to extend the limitation of attention resource. We studied the impact of feedback on attention by varying its type and modality. An experimental system was developed to observe how accurately the participants performed the pattern-matching task with differential feedback provided on a real-time basis based on the ADHD diagnostic model. Six university students participated in this study with 6 different feedback conditions and controlled conditions. The participants experienced the feedbacks before experiment. They was asked two hundred tasks in four feedback conditions. The difference of feedback effect according to different modality is to find within a subject. The results indicated that the combined feedback of cognitive with perceptual stimulus led better performance than the combined of perceptual feedbacks.

• Journal of Veterinary Clinics
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• v.31 no.2
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• pp.129-132
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• 2014

A 4-year-old, intact female Border Collie was presented for evaluation of hearing impairment. Clinical, neurological, otoscopic and magnetic resonance imaging examinations were carried out to determine the cause of hearing loss, but no remarkable change was found. Then, brainstem auditory-evoked response test was performed to assess hearing loss, and the dog had a bilateral sensorineural deafness was revealed. Since possible causes of acquired hearing loss were ruled out by several examinations and history taking, bilateral later-onset deafness was suspected to be genetic and not congenital. This report suggested the possibility that dogs had inherited later-onset sensorineural deafness.

• Journal of the korean academy of Pediatric Dentistry
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• v.23 no.3
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• pp.582-592
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• 1996

본 실험은 삼차신경 자극으로 발생되는 체성 감각 유발 전위에 대한 국소마취제의 효과를 관찰하였다. 나트륨 통로차단을 통하여 약리작용을 나타내는 것으로 알려져 있는 리도카인를 뇌 피질에 국소 투여한 후 삼차신경의 체성 감각유발 전위의 강도및 지연시간을 측정하였다. 케타민으로 마취된 흰쥐의 대측성 구레나룻 자극후 뇌의 체성 감각영역으로부터 기록되는 유발전위를 분석한 결과, 리도카인을 뇌 피질에 국소 투여시 유발전위의 강도 및 지연시간의 감소가 나타났으며, 필드 전위의 형태는 이상성 (양극성 및 음극성) 혹은 삼상성 (양극성, 음극성 및 양극성) 의 파형으로 나타났다. 필드 전위의 발생 부위는 뇌 피질의 중대뇌동맥의 상행지 상방영역이었다. 본 실험에서 나타난 초기 전위변동은 피질판 상층에 존재하는 신경세포의 탈분극 과청에 의하여 생성되고 후기의 전위 변동은 동일 영역의 하층 신경세포에서 과분극 혹은 재분극이 발생한 결과라고 유추된다. 따라서 삼차신경계의 체성 감각 영역에서는 피질 상층및 하층의 과립성 피라미드 세포의 순차적인 활성화에 의하여 기본적인 신경 회로망이 형성되어 있으며 생리적 자극으로 유발되는 필드 전위는 이러한 신경망를 통하여 발생될 것으로 사료된다.

• Herbal Formula Science
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• v.7 no.1
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• pp.143-151
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• 1999

To evaluate the neurotoxic effect of oxygen radicals in cultured mouse spinal dorsal root ganglion(DRG) neurons, cytotoxicity was determined by MTT assay after cultured DRG neurons were grown in the media containing various concentrations of glucose oxidase(GO). In addition, neuroprotective effect of herb extract, Epimedium Koreanum Nakai was examined by MTT assay in cultured DRG neurons. Cell viability of cultured DRG neurons was remarkably decreased by GO in dose- and time-dependent manner, and Epimedium Koreanum Nakai protected remarkably GO-induced neurotoxicity in these cultures. From the above results, it is suggested that oxygen radicals is toxic in cultured mouse DRG neurons, and herb extracts such as Epimedium Koreanum Nakai are effective in prevention of the neurotoxicity induced by oxygen radicals in cultured mouse DRG neurons.