• Title/Summary/Keyword: 갈륨-67

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The Usefulness of Ga-67 SPECT Imaging to Detect the Non-Hodgkin's Lymphoma: Comparison with Ga-67 Planar and SPECT Imaging (비호지킨 림프종의 진단에서 갈륨 SPECT의 유용성: 평면영상과 SPECT영상의 비교)

  • Wang, Jing;Bae, Sang-Kyun;Yum, Ha-Yong
    • The Korean Journal of Nuclear Medicine
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    • v.30 no.1
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    • pp.139-144
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    • 1996
  • 갈륨스캔은 여러 종류의 염증성 질환 및 종양을 발견하기 위해 사용되고 있다. 특히 림프종은 갈륨스캔에서 양성율이 비교적 높은 종양으로 알려져 있다. 하지만 기존의 평면 영상만으로는 작은 크기의 종괴나 다른 장기에 의해 가려져 있는 경우에 위음성 결과를 보일 수 있었다. 최근 단일광자 방출 전산화 단층촬영(SPCET)을 도입하여 평면영상에 비해 더 나은 공간해상력으로 많은 정보를 얻고 있다. 저자들은 비호지킨 림프종 환자 30명을 대상으로 갈륨스캔 평면영상과 SPECT 영상을 얻어 비교하였다. 병변의 부위별로 두경부, 흉부, 복부에서 평면영상의 예민도는 각각 71%, 73%, 81%였으며, SPECT 영상의 예민도는 91%, 93%, 96%였다. CT 등 방사선학적 검사소견과 임상소견을 기준으로 하였을 때 위음성율은 평면영상의 경우 24%, SPECT 6.5%였다. 장의 방사능으로 인한 섭취와 폐문부 및 침샘의 비대칭적 섭취로 인한 위양성례가 4예 있었다. 결론적으로 비호지킨 림프종의 진단 및 병기를 결정하는데 있어서 갈륨스캔이 유용하며, SPCET 영상을 얻음으로써 더 나은 해부학적 위치 및 정확한 범위를 보여 줄 수 있을 것으로 생각된다.

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Method for Making High Purity Gallium by Electrowinning (전해채취에 의한 Gallium의 정제기술)

  • Choi, Young-Jong;Hwang, Su-Hyun;Jeon, Deok-Il;Han, Kyu-Sung
    • Resources Recycling
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    • v.23 no.6
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    • pp.63-67
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    • 2014
  • Gallium is an important material and is used by industry of oxide semi-conductor and LED chip. However, the most of the gallium-containing waste resources became outflow abroad and the most of which is imported from oversea by following technical problem and low circulation rate. In this research, the recovery of high purity Gallium metal from Gallium scrap, which containing about 30% of Gallium, was investigated by using hydro-metallurgical process. As pretreatment, the Gallium scrap was pulverized and leached by strong acid such as hydro chloric acid. At the leached solution, Indium was separated as an Indium sponge by substitution reaction and then Gallium and Zinc hydroxide separated and filtrated using strong alkaline solution such as sodium hydroxide by precipitation method. Also, Gallium metal and Zinc metal was recovered by electrowinning method. To make an electrolytic solution, Gallium and Zinc hydroxide was leached by strong alkaline solution. Finally, High purity Gallium metal was recovered by vacuum refining process to remove the Zinc impurity.

Altered Biodistribution of Gallium-67 in a Patient with Multiple Factors Influencing Iron-transport Protein Saturation (철운반단백질 포화정도에 따른 Gallium-67 체내분포의 변화: 증례보고)

  • Choi, Joon Young;Kim, Sang Eun;Lee, Kyung Han;Kim, Byung-Tae
    • The Korean Journal of Nuclear Medicine
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    • v.32 no.1
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    • pp.114-119
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    • 1998
  • We present a case of a young female patient with fulminant hepatitis who showed an altered biodistribution of Ga-67, after being scanned twice at 10 month intervals. On initial scan, uplake of Ga-67 was increased in the liver, kidneys, and skeletons. Increased hepatic Ga-67 uptake may be explained by increased transferrin unbound Ga-67 that was taken up by the inflamed liver. The saturation of iron-binding proteins due to multiple transfusions may lead to increased renal and skeletal Ga-67 uptake. On follow-up scan hepatic Ga-67 uptake was markedly increased. Also increased Ga-67 uptake in the axial skeleton and normalized renal uptake were shown. The findings were consistent with iron deficiency anemia. This case demonstrates altered Ga-67 biodistribution associated with multiple transfusions, fulminant hepatitis, and iron deficiency anemia.

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A Case of Muscular Sarcoidosis diagnosed by Gallium-67 Scintigraphy and Magnetic Resonance Imaging (갈륨 신티그라피와 자기공명영상으로 진단한 근육 유육종증)

  • Sohn, Hyung-Sun;Kim, Euy-Neyng
    • The Korean Journal of Nuclear Medicine
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    • v.33 no.6
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    • pp.543-547
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    • 1999
  • Gallium-67 scintigraphy is helpful in the assessment of active extrapulmonary sarcoidosis. Muscular involvement of sarcoidosis is often asymptomatic or nonspecific, and laboratory examinations do not provide convincing evidence of muscular involvement We report a case of muscular sarcoidosis, which was detected by gallium-67 scintigraphy. In a patient who was suffering from fever and arthralgia of knee joint, gallium-67 scintigraphy showed mediastinal and hilar involvement of sarcoidosis with unexpected extensive muscular uptake. Magenetic resonance imaging revealed the detailed depiction of intramuscular infiltration of sarcoid granuloma. Gallium-67 scintigraphy is useful in detecting inflammatory muscular involvement of sarcoidosis as well as other multiorgan involvement.

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Design of High Gain Differential Amplifier Using GaAs MESFET's (갈륨비소 MESFET를 이용한 고이득 차동 증폭기 설계)

  • 최병하;김학선;김은로;이형재
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.17 no.8
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    • pp.867-880
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    • 1992
  • In this paper, a circuit design techniques for Improving the voltage gain of the GaAs MESFET single amplifier is presented. Also, various types of existing current mirror and proposed current mirror of new configuration are compared. To obtain the high differential mode gain and low common mode gain, bootstrap gain enhancement technique Is used and common mode feedback Is employed In the design of differential amplifier. The simulation results show that designed differential amplifier has differential gain of 57.66dB, unity gain frequency of 23.25GHz. Also, differential amplifier using common mode feedback with alternative negative current mirror has CMRR of 83.S8dB, stew rate of 3500 V /\ulcorners.

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The Development of Automatic Chemical Processing System for $^{67}Ga$ Production ($^{67}Ga$ 생산용 화학처리 자동화 장치 개발)

  • Lee, Dong-Hoon;Kim, Yoon-Jong;Suh, Yong-Sup;Yang, Seung-Dae;Chun, Kwon-Soo;Hur, Min-Goo;Yun, Yong-Ki;Hong, Seung-Hong
    • Journal of Radiation Protection and Research
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    • v.28 no.1
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    • pp.25-33
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    • 2003
  • The automatic system for $^{67}Ga$ production using for the diagnosis of malignant tumor has been developed. A solvent extraction and an ion exchange chromatography were used for the separation $^{67}Ga$ from the irradiated enriched $^{68}Zn$. This system consisted of a solvent separation unit which was composed of micro conductivity cells, air supply tubes, solvent transfer tubes, solenoid valves and glasses, a PLC based controller and a PMU user interface unit for automation. The radiation exposure to the workers and the production time can both be reduced by employing this system during the $^{67}Ga$ production phase. After all, the mass production of $^{67}Ga$ with high efficiency was possible.

Comparison of Radionuclide Bone and Gallium Scans in the Therapeutic Evaluation of Bone Lymphoma (골임파종의 치료효과판정을 위한 핵의학적 골스캔과 갈륨스캔의 비교)

  • Moon Tae-Yong;Hwang, In-Tae;Kim, E. Edmund
    • The Korean Journal of Nuclear Medicine
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    • v.28 no.3
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    • pp.377-383
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    • 1994
  • Objective : We retrospectively analysed $^{99m}Tc$-MDP bone and $^{67}Ga$ scans to evaluate therapeutic response of bone lymphoma among patients with complete remission. Subjects and Methods : We reviewed 35 cases with an increased uptake finding $^{99m}Tc$-MDP bone scans and 16 $^{67}Ga$ scans that were follow-up studies during and after therapy. The $^{99m}Tc$-MDP bone and $^{67}Ga$ scans were graded visually from 1 to 4 in which grade 3 means same uptake density as that of normal sacroiliac articulation in bone scan and normal liver in $^{67}Ga$ scan, respectively. Results: The improvement findings during and after therapy were found in 66.0% (19/ 29) and 72.7% (24/33) with $^{99m}Tc$-MDP bone scan, 84.6% (l1/13) and 86.7% (13/15) with $^{67}Ga$ scan, respectively. The mean grades of the uptake density in $^{99m}Tc$-MDP bone scan were 3.06 before, 2.34 during, 1.75 after therapy. Those in the $^{67}Ga$ scan were 3.22 before, 1.42 during 1.30 after therapy. Conclusion. $^{67}Ga$ scans appeared more sensitive than bone scans in evaluating therapeutic response of bone lymphoma.

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Thermal characteristics of $W_{67}N_{33}$/GaAs structure (PECVD방법으로 형성한 $W_{67}N_{33}$/GaAs구조의 열적 특성)

  • Lee, Se-Jeong;Hong, Jong-Seong;Lee, Chang-U;Lee, Jong-Mu;Kim, Yong-Tae;Min, Seok-Gi
    • Korean Journal of Materials Research
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    • v.3 no.5
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    • pp.443-450
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    • 1993
  • Self-alignment gatc Schottky contact structure on Si- implanted GaAs was formed by plasma enhanced chemical vapor dcposirion. Tungsten nitride thin films (ahclut 1600$\AA$) \vcre dopositcd on GaAs at $350^{\circ}C$ in order to fahricarc GaAs 1Cs and ttwn rapidly annealed at $750^{\circ}C$ to $900^{\circ}C$. Thermal charac tcristics of PECVD)-$W_{67}N_{43}$/GaAs structure were investigated by X-ray diffraction, photolumintesccnce. and optical deep level transient specrroscopy. Results revealed that $W_{67}N_{33}$ gate was more thermally sta ble with GaAs substrate than W gate and Si atoms implanted In $W_{67}N_{33}$/GaAs structure became morr active than those In W/GaAs after annealing. I-V characteristics of $W_{67}N_{33}$/GaAs diod c exhibired a nearly ideal diode behavior. The termal stability of $W_{67}N_{33}$/GaAs diode was better than that of W/GaAs diode with the post annealing at temperatures from 800 to $900^{\circ}C$ for 20s without As overpressure.

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Discrimination of Postradiotherapy Lung Fibrosis from Recurrence by Gallium-67 Scan in Lung Cancer (갈륨 스캔을 이용한 폐암의 치료 후 섬유성 변성과 재발의 감별)

  • Ryu, Sam-Uel;Lee, Jae-Tae
    • Radiation Oncology Journal
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    • v.9 no.1
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    • pp.81-85
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    • 1991
  • The differentiation between post-radiotherapy lung fibrosis and tumor recurrence is often a dilemma to physicians. Twenty two patients with lung cancer who had received 45~60 Gy to the chest were chosen to study the possible role of gallium-67 scan. Seventeen squamous cell carcinomas were treated with only radiotherapy, 3 small cell carcinomas with combination chemotherapy, 2 adenocarcinomas with lobectomy. A total of 8 patients with pneumonitis with or without fibrosis and recurrence showed uptake of gallium at the site of inflammation. Of the 12 recurrences and residual diseases after radiotherapy, positive gallium uptake was present in 11 cases (92%). Of the 10 recurrence-free cases, all the 5 patients with pneumonitis revealed gallium accumulation. However, 4 of the 5 patients (80%) with recurrence-free fibrosis have not accumulated gallium in the fibrotic areas. Fibroses in S patients were developed after 8 months of completion of radiotherapy. These facts suggest that gallium-67 scan after 1 year post-treatment may aid for the discrimination of fibrosis from tumor recurrence unless pneumonitis is present.

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