• Title/Summary/Keyword: 간 질환

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U-헬스케어를 위한 IEEE 11073 기반 원격 생체정보 모니터링 보안 기술

  • Na, Jae-Uk;Yun, Eun-Jun;U, Yeon-Gyeong;Park, Jong-Tae
    • Information and Communications Magazine
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    • v.29 no.10
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    • pp.66-73
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    • 2012
  • 전 세계적으로 노령인구가 급격히 증가하면서 만성질환자도 급증하고 있는 추세이다. 또한, 고도화된 현대사회와 과도한 업무, 서양화된 식습관, 그리고 운동부족은 젊은 층에서의 성인병 및 만성질환 증가를 부추기고 있다. 만성질환의 증가는 의료비 증가로 이어지고 결국은 국가재정 부담으로 돌아가게 된다. 만성질환자의 대부분은 지속적인 생체정보 측정과 이를 통한 관리가 필수적인데 매번 병원을 방문해 관리하는 것은 현실적으로나 비용적인 측면으로나 무리가 있는 것이 사실이다. 이러한 문제를 해결하고 언제 어디서나 시간과 공간에 구애받지 않고 생체정보를 원격에서 측정하고 관리 받을 수 있도록 하는 것이 U-헬스케어 서비스이다. U-헬스케어 서비스는 전통적인 의료 서비스에 정보통신 기술을 접목한 형태로 고령인구 및 만성질환자의 지속적인 관리를 위해 현재 주목 받고 있는 기술이다. U-헬스케어 서비스의 가장 중요하면서도 기본적인 요소는 원격지 사용자의 생체정보를 측정하고 수집할 수 있는 원격 생체정보 모니터링 기술이다. 이를 위해서는 다양한 종류의 생체정보 측정기기가 필요한데 장비나 시스템 간 통신 인터페이스의 상호 호환성이 매우 중요하다. 본 논문에서는 원격 생체정보 모니터링을 위한 표준 기술인 IEEE 11073 PHD를 소개하고 현재 IEEE 11073 PHD 표준에서 명시하고 있지 않은 보안 문제점과 필요 기술들을 분석하고자 한다. 또한, IEEE 11073 PHD에서 IEEE 11073-20601 표준 프로토콜을 이용한 사용자 인증 구조를 제안한다.

A Study on the Assistive System for Body Correction (신체 교정을 위한 보조 시스템에 관한 연구)

  • Kim, Ho-Joon;Chung, Jae-Pil
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.4 no.4
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    • pp.231-235
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    • 2011
  • In these day, the number of people who have an abnormal posture caused by bad habit are increasing. Therefore, people suffer various disease and symptoms. For correcting the posture to cure, we need continuous monitor, expenditure of time and money. In this study, we develop a posture correcting aid system in other to monitor a posture continuously and leads to pose correctly and records postural variation which are attached to the neck and the waist. The devised system showed good potential for the correct posture guide and a cure of postural defect.

Assessment of PVC (Premature Ventricular Contraction) Arrhythmia by R-R Interval in ECG (심전도 R-R 간격 정보를 이용한 심실조기수축 부정맥 검출)

  • Yoon, Tae-Ho;Lee, Sun-Ju;Kim, Kyeong-Seop;Lee, Jeong-Whan
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.2 no.2
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    • pp.15-21
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    • 2009
  • This paper proposes a novel algorithm to assess the abnormal heart beats such as PVC (Premature Ventricular Contraction) and its subsequent RUNs. Our Arrhythmic detection scheme is based on only the R-R Interval features extracted from ECG waveforms and MIT-BIH arrhythmia database is evaluated to validate the efficiency of our algorithm in terms of sensitivity, specificity, FPR(%) and FNR(%).

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Development of Mobile Healthcare System Using ECG Measurement (심전도 측정을 이용한 모바일 헬스케어 시스템 개발)

  • Kim, Seong-Woo;Shin, Seung-Chul
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.18 no.8
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    • pp.2008-2016
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    • 2014
  • With the increased attention about health care and management of heart diseases, ubiquitous healthcare services and related devices have been actively developed recently. In this paper we developed a mobile healthcare system which consists of smartphone and patch-type ECG measuring device. This system is capable of monitoring, storing, and sending bio signals such as ECG, heart rate, heart rate variability as well as exercise management functions through heart rate zones. With monitoring bio signal continuously by mobile healthcare system and wearable device like us, people can prevent chronic disease and maintain good health. Here we report our implementation results on real platforms.

Frailty assessed by the electronic frailty index and its impact on health outcomes in older adults with chronic diseases: a systematic review (전자허약지수(electronic frailty index)를 활용한 만성질환 노인의 허약평가와 건강결과 간의 관계: 체계적 고찰)

  • Jung-Wook Shin;Min-Young Yu;Youn-Jung Son
    • Journal of Korean Biological Nursing Science
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    • v.25 no.4
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    • pp.229-242
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    • 2023
  • Purpose: The electronic frailty index (eFI), which is derived from electronic health records, has been recommended as screening tool for frailty due to its accessibility and ease of use. The objective of this systematic review was to identify the prevalence of frailty assessed by the eFI and its influence on health outcomes in older adults with chronic diseases. Methods: We searched PubMed, Embase, Web of Science, CINAHL, SCOPUS, Cochrane, Google search, and nursing journals in Korean from January 2016 to December 2022. Results: Twelve studies were analyzed. The eFI score, based on routine clinical data, was associated with adverse health outcomes. The most frequent outcome studied was mortality, and the eFI was associated with increased mortality in nine studies. Other outcomes studied included hospitalization, length of stay, readmission, and institutionalization in relation to hospital care usage, and cardiovascular events, stroke, GI bleeding, falls, and instrumental activities of daily life as health conditions. Conclusion: Early identification of frailty in older adults with chronic diseases can decrease the burden of disease and adverse health outcomes. The eFI has a good discriminative capacity to identify frail older adults with chronic diseases.

A Drug-Induced Liver Injury by Western Medication (양약으로 유발된 약인성 간손상 환자 임상보고)

  • Son, Chang-gue
    • The Journal of Internal Korean Medicine
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    • v.36 no.1
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    • pp.69-75
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    • 2015
  • Objectives : To investigate the clinical features of drug-induced liver injury (DILI) and traditional Korean medicine (TKM) -based management. Methods : A female patient diagnosed with DILI caused by Western drugs had been treated with Oriental therapies, then the subjective clinical outcome and biochemical parameters were monitored. Results : A 73-year-old female had taken Western drugs (nonsteroidal anti-inflammatory and skeletal muscle relaxants) for about 3 months, and complained of severe abdominal discomfort and tiredness. Her RUCAM score was 9, which met the criteria for DILI (AST 90 IU/L, ALT 100 IU/L, ALP 191 IU/L, and GGT 614 IU/L). She was treated with herbal drugs, moxibustion, and acupuncture, and her symptoms completely resolved, with normalized hepatic enzymes within two weeks. Conclusions : This case report provides a clinical characteristic for a typical DILI caused by Western medicine, and shows an example of a TKM-based application.

A Case of Budd-Chiari Syndrome Which Shows Space Occupying Lesion on Liver Scan (간 스캔상 공간점유병소의 소견을 보인 Budd-Chiari증후군 - 1예 보고 -)

  • Lee, Jeong-Hae;Lee, Youn-Ha;Seo, Dae-Won;Jang, Tae-Jong;Hwang, In-Shup;Kim, Young-Jung;Kim, So-Yon;Lee, Gwon-Jun
    • The Korean Journal of Nuclear Medicine
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    • v.28 no.3
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    • pp.397-401
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    • 1994
  • A twenty-one-year-old man visited our hospital due to abdominal distension for a month. On the physical examination, there was severe abdominal distension with fluctuation and shifting dullness. The routine laboratory results were within normal range. On the Magnetic Resonace angiography, there wasn't any blood flow within the right and middle hepatic vein. So we concluded that the etiologic disease was Budd-Chiari syndrome. On the liver scan, there was cold area(absence of radiouptake) on entire right lobe of the liver, increased uptake on the bone marrow and showed splenomegaly. This finding was similar to the liver mass occupying right lobe with underlying chronic liver disease. On the previous reports, it is quite uncommon finding that Budd-Chirari syndrome shows lesion like space occupying one on the liver scan. So we report this case with a review of the literature.

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A case of hepatopulmonary syndrome in a child with fatty liver disease secondary to hypopituitarism after craniopharyngioma resection (지방간을 가진 소아에서 두개인두종 절제술 후의 뇌하수체기능저하증으로 인해 급격하게 진행된 간-폐 증후군 1예)

  • Im, Sun Ju;Park, Hyeon Seok;Lee, Hyoung Doo;Park, Jae Hong;Park, Hee Ju
    • Clinical and Experimental Pediatrics
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    • v.50 no.8
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    • pp.794-798
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    • 2007
  • Hepatopulmonary syndrome is a triad that includes: hepatic dysfunction, intrapulmonary vascular dilatation and abnormal arterial oxygenation. The incidence of intrapulmonary vascular dilatations, in adults with end-stage liver disease, has been reported to be 13% to 47%, however the incidence in children is unclear and the cases in Korean children have never been reported. The hepatopulmonary syndrome may occur as a result of chronic liver disease following nonalcoholic steatohepatitis in children with hypothalamic or pituitary dysfunction. We report a case of hepatopulmonary syndrome in a 13-year-old child who had rapidly progressive liver dysfunction secondary to panhypopituitarism after craniopharyngioma resection. Careful monitoring and treatment of endocrine abnormalities and metabolic status, as well as liver function, are required in all children undergoing pituitary tumor resection.

TNF-α stimulated IL-8 and IL-10 expression in monocytes from patients with chronic granulomatous disease (만성육아종질환 환자 단핵구에서 TNF-α 자극에 의한 IL-8과 IL-10의 발현 양상)

  • Shin, Kyung-Sue
    • Clinical and Experimental Pediatrics
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    • v.51 no.10
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    • pp.1096-1101
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    • 2008
  • Purpose : Patients with chronic granulomatous disease (CGD) have genetic mutations in a component of the NADPH oxidase enzyme that is necessary for the generation of the superoxide anion. The profound defect in innate immunity is reflected by the patients susceptibility to catalase-positive bacteria and fungi. In addition, CGD patients display signs of persistent inflammation, which is not associated only with deficient superoxide anion production. The aim of this study was to elucidate the cytokine responses in CGD patients after $TNF-{\alpha}$ stimulation. Methods : Heparinized blood samples were collected from 8 CGD patients and 10 healthy volunteers. Monocytes ($1{\times}10^6cell/well$) isolated by the magnet cell isolation system were incubated with a constant amount of $TNF-{\alpha}$ (10 ng/mL) at $37^{\circ}C$ for 6 h. Incubated cells were harvested at 60-min intervals for IL-8 and IL-10 mRNA analysis, and the supernatant was collected at the same intervals to determine IL-8 and IL-10 expression. Monocytes from healthy volunteers were also incubated with antioxidants followed by $TNF-{\alpha}$ stimulation for IL-8 and IL-10 expression. Results : In CGD patients, a high expression of IL-8 together with a significantly higher IL-10 expression than in the healthy controls was seen after $TNF-{\alpha}$ stimulation. Moreover, normal monocytes treated with antioxidants exhibited increased IL-8 responses. Conclusion : The absence of phagocyte-derived reactive oxidants in CGD might be associated with a dysregulated production of pro- and antiinflammatory cytokines. Additional research related to reactive oxidants is needed to clarify the role of cytokines in CGD patients.

Factors associated with Experience of Diagnosis and Utilization of Chronic Diseases among Korean Elderly : Focus on Comparing between Urban and Rural Elderly (한국 노인의 만성질환 진단경험 및 의료이용에 관련된 요인 : 도시와 농촌 간 비교를 중심으로)

  • Lee, Min Ji;Kown, Dong Hyun;Kim, Yong Yook;Kim, Jae Han;Moon, Sung Jun;Park, Keon Woo;Park, Il Woo;Park, Jun Young;Baek, Na Yeon;Son, Gi Seok;Ahn, So Yeon;Yeo, In Uk;Woo, Sang Ah;Yoo, Sung Yun;Lee, Gi Beop;Lim, Soo Beom;Jang, Soo Hyun;Jang, In-Deok;Jeon, Jeong-U;Jeong, Su Jin;Jung, Yeon Ju;Cho, Seong Geon;Cha, Jeong Sik;Hwang, Ki Seok;Lee, Tae-Jun;Lee, Moo-Sik
    • Journal of agricultural medicine and community health
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    • v.44 no.4
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    • pp.165-184
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    • 2019
  • Objectives: The purpose of this study was to identify and compare the difference and related factors with general characteristic and health behaviors, a experience of diagnosis and treatment of chronic diseases between rural and urban among elderly in Korea. Methods: We used the data of Community Health Survey 2017 which were collected by the Korean Center for Disease Control and Prevention. The study population comprised 67,835 elderly peopled aged 65 years or older who participated in the survey. The chi-square test, univariate and multivariate logistic regression analysis were used to analyze data. Results: We identified many significant difference of health behaviors, an experience of diagnosis and treatment with chronic diseases between rural and urban. Compared to urban elderly, the odds ratios (ORs) (95% confidence interval) of rural elderly were 1.136 (1.092-1.183) for diagnosis of diabetes, 1.278 (1.278-1.386) for diagnosis of dyslipidemia, 0.940 (0.904-0.977) for diagnosis of arthritis, 0.785(0.736-0.837) for treatment of arthritis, 1.159 (1.116-1.203) for diagnosis of cataracts, and 1.285(1.200-1.375) for treatment of cataracts. In the experience of diagnosis and treatment of chronic diseases, various variables were derived as contributing factors for each disease. Especially, there were statistically significant difference in the experience of diabetes diagnosis, arthritis diagnosis, cataract diagnosis and dyslipidemia except for hypertension diagnosis (p <0.01) between urban and rural elderly. There were statistically significant differences in the experience of treatment for arthritis and cataract (p <0.01), but there was no significant difference in the experience of treatment for hypertension, diabetes, dyslipidemia between urban and rural elderly. Conclusion: Therefore, it would be necessary to implement a strategic health management project for diseases that showed significant experience of chronic diseases with diagnosis and treatment, reflecting the related factors of the elderly chronic diseases among the urban and rural areas.