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A Drug-Induced Liver Injury by Western Medication  

Son, Chang-gue (Liver and Immunology Research Center, Oriental Medical College in Dae-Jeon University)
Publication Information
The Journal of Internal Korean Medicine / v.36, no.1, 2015 , pp. 69-75 More about this Journal
Abstract
Objectives : To investigate the clinical features of drug-induced liver injury (DILI) and traditional Korean medicine (TKM) -based management. Methods : A female patient diagnosed with DILI caused by Western drugs had been treated with Oriental therapies, then the subjective clinical outcome and biochemical parameters were monitored. Results : A 73-year-old female had taken Western drugs (nonsteroidal anti-inflammatory and skeletal muscle relaxants) for about 3 months, and complained of severe abdominal discomfort and tiredness. Her RUCAM score was 9, which met the criteria for DILI (AST 90 IU/L, ALT 100 IU/L, ALP 191 IU/L, and GGT 614 IU/L). She was treated with herbal drugs, moxibustion, and acupuncture, and her symptoms completely resolved, with normalized hepatic enzymes within two weeks. Conclusions : This case report provides a clinical characteristic for a typical DILI caused by Western medicine, and shows an example of a TKM-based application.
Keywords
drug-induced liver injury; traditional Korean medicine; herbal medicine; RUCAM score;
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Times Cited By KSCI : 2  (Citation Analysis)
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