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An Analysis on the Occupational Index Status and Prospect Perception to Librarian as Job in South Korea (사서직의 직업지표 현황 및 전망 인식 분석 연구)

  • Lee, Jong-Moon
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.24 no.3
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    • pp.99-120
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    • 2013
  • This study aimed to propose the approach to identify and solve the problems by analyzing the present occupation index of librarians and the future occupation index of librarians after 10 years through the comparison with other jobs. In accordance with the investigation on the LIS students and librarians, the present wage level and the estimated wage level after 10 years were lower than that for other jobs and the employment demand was also lower. Both the students(58.4%) and the librarians(64.2%) considered that the number of full-time employment and the turnover were lower than other jobs. As a result of the analysis, first, this paper proposed to change part-time workers into full-time workers for improving the low wage issue of librarians. Second, '1 public library per 50,000 citizen' was suggested to increase the employment of librarians. Finally, it is proposed to cancel the project to contract out the operation of public libraries and BTL implementation.

Rare Disease Research and Orphan Drug Development (희귀질환 연구와 치료제 개발 동향)

  • Lee, Shinhaeng;Lee, Jangik I.
    • Korean Journal of Clinical Pharmacy
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    • v.23 no.1
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    • pp.1-13
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    • 2013
  • 희귀질환이란 일반적으로 그 유병율이 인구 일만 명당 5명 이하인 질환을 말한다. 세계에는 약 7,000여종의 희귀질환이 알려져 있고 학술지에 매 주 대략 5종의 새로운 희귀질환이 보고되고 있다. 희귀 의약품(orphan drug)이란 희귀질환치료제 또는 수익성이 없어 개발을 기피하는 일반질환 치료제로서 정부가 지정한 의약품을 말한다. Orphan 의약품의 개발에는 많은 장점이 있다. Orphan 의약품으로 정부의 지정을 받으면 세금감면을 통한 연구비 지원, 임상시험 비용 지원, 신약허가 심사비 면제, 시장독점권 부여 등의 특혜가 주어진다. 희귀질환의 대부분은 단순한 유전적 결함에 의하는 경우가 많아 치료제의 표적발견이 비교적 쉬우므로 개발 성공률이 높고, 임상시험기간이 짧으며, 시판허가를 받을 확률이 높아 연구개발비용이 적게 든다. 그 결과 전세계 orphan 의약품 시장은 최근 매년 6%씩 성장하여 2014년에는 약 1,120억달러의 시장을 형성할 것으로 추정된다. Orphan 의약품 시장은 현재 매년 8.9%씩 성장하고 글로벌 시장의 51%를 점유하는 미국을 중심으로 확장되어 가고 있으며, 총매출액의 64.3%가 유전자재조합의약품에 의한 것으로 알려져 있다. 이러한 의약품시장의 변화와 사회적 요구에 부응하여 한국 또한 희귀질환 치료제 개발의 활성화를 위해 재정적 지원체계를 구축하고, 허가관리를 개선하며, 법률적 제도를 완비하는 과정에 있다. 현재 희귀질환의 치료적 타겟을 찾아 신물질이나 기존의 약물을 발굴하는 과정이 주로 대학이나 연구 중심 병원에서 이루어지고 있다. 제도가 잘 정립되어 있는 미국 시장을 겨낭하여 orphan 의약품 개발을 전략적으로 수행한다면 큰 성공을 거둘 수 있을 것으로 기대된다.

The Influence of Foot Reflexology Massage Using Aroma Oil on Sleep and Pain in Cancer Patients (아로마 오일을 이용한 발 반사 마사지가 암 환자의 수면과 통증에 미치는 효과)

  • Lee, Seong-Jin;Kim, In-Lan;Kang, Kyung-Koo;Moon, Kyung-Rye
    • The Journal of the Korea institute of electronic communication sciences
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    • v.8 no.10
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    • pp.1609-1616
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    • 2013
  • As a disease, cancer is incurable when being diagnosed with that makes people have a fear of death. It is impacts a person's entire life by lowering her physical, psychological, social, economical, and spiritual conditions. The cancer incidence is continually increasing and its cancer death is 144.4 per 100,000 people, according to the National Center for Health Statistics(2010). The purpose of this study is to investigate the effects of foot reflexology massage using aroma therapy, a part of alternative medicine. It aims to determine whether the use of aroma oils improve the sleep and pain condition among patients who are either currently receiving a foot reflexology massage or in need of one.

Genetic Variations of Congenital Hypothyroidism (선천성 갑상샘기능저하증의 유전자 변이)

  • Lee, Yong-Wha;Lee, Dong-Hwan
    • Journal of Genetic Medicine
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    • v.7 no.1
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    • pp.9-15
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    • 2010
  • Congenital hypothyroidism (CH) is detected at a rate of 1 in 3,000 to 4,000 live births, making it the most common congenital endocrine disorder worldwide. CH is most commonly caused by defects in thyroid development leading to thyroid dysgenesis or dyshormonogenesis. Congenital hypothyroidism is usually sporadic, but up to 2% of cases of thyroid dysgenesis are familial, and CH caused by organification defects is often inherited in a recessive manner. The candidate genes associated with this genetically heterogeneous disorder fall into two main groups: those causing thyroid gland dysgenesis and those causing dyshormonogenesis. Genes associated with thyroid gland dysgenesis include the TSHR gene in nonsyndromic CH, and Gsa and the thyroid transcription factor (TTF-1, TTF-2, and Pax-8) genes, which are associated with different complex syndromes that include CH. Among genes associated with dyshormonogenesis, the TPO and TG genes were initially described, and more recently PDS, NIS, and THOX2 gene defects. There is some evidence for a third group of CH conditions associated with iodothyronine transporter defects that are, in turn, associated with severe neurological sequelae.

Classification method of chronic gastritis by modeling of pulse signal (맥파 모델링을 통한 만성위염 분류 기법)

  • Choi, Sang-Ho;Shin, Ki-Young;Shin, Jitae
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.5 no.3
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    • pp.144-151
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    • 2012
  • Chronic gastritis is the disease that is occuring in one in every 10 persons in Korea. In western medicine, endoscopy is needed to diagnose chronic gastritis, but it causes patients a pain and budget of expense. According to the TEM (Traditional Eastern Medicine), on the other hand, the 'Guan' position of the right wrist is related to a stomach. Thus we can diagnosis chronic gastritis by analyzing of pulse signal. However, pulse signal diagnosis is depended on oriental doctor's knowledge and experience. In this study, a systematic approach is proposed to analyze the computerized pulse signal. The pulse signals are firstly pre-processed, Gaussian model is adopted to fit the pulse signal, and then some related parameters are extracted from the model. Consequently, disease-sensitive parameters are selected by T-test and statistical difference. Finally, the selected parameters are entered into a Fuzzy C-Means (FCM) algorithm for classification. Classification results show that healthy persons and chronic gastritis patients are 95% and 87%, respectively.

Face Feature Extraction for Child Ocular Inspection and Diagnosis of Colics by Crying Analysis (소아 망진을 위한 얼굴 특징 추출 및 영아 산통 진단을 위한 울음소리 분석)

  • Cho Dong-Uk;Kim Bong-Hyun
    • The KIPS Transactions:PartB
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    • v.13B no.2 s.105
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    • pp.97-104
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    • 2006
  • There is no method to control for the child efficiently when disease happens who cannot be able to express his symptoms. Therefore, doctor's diagnosis depends on inquiring from child's patients, that leads to wrong diagnosis result. For this, in this paper, we would like to develop child ocular inspection, auscultation diagnosis instruments, using Oriental medicine principle that living body signal of five organs and six hallow organs which reflects patients face and voice We would like to get more accurate diagnosis result for child's symptoms from doctor's intuition on the basis of diagnostic sight visualization, objectification, quantization itself. This paper develops color revision, YCbCr application, and face color selection and five sensory organs and nose or apex extraction method etc, in child ocular inspection by first work achievement sequence among the whole development systems. Also, in occasion of child auscultation, crying characteristics of colics through pitch, intensity and formant analysis is numerized and objectifies doctor's intuition through this. Finally, experiments are performed to verify the effectiveness of the proposed methods.

Natural Hazard Research in Geography (지리학 측면에서의 자연재해연구)

  • 김욱중
    • Water for future
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    • v.22 no.4
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    • pp.415-415
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    • 1989
  • 자연재해연구는 인간.자연환경 관계를 연구하는 학문이다. 금세기초 환경결정론, 환경가능주의, 그리고 인지에 의한 행동과학주의로 연구 Paradigm이 변화.발전되어 오며서 지리학에서도 이러한 이론적 방법론의 바탕위에 인간-자연환경 관계를 설명하려고 노력했다. 1920년대 초 Barrow가 인간생태학 개념을 발표, 1950, 1960년대 이에 영향받은 White, Kate와 Burton 같은 미국의 자연재해지리학자들은 미국에서 홍수재해문제를 인간적응, 특히 "인식"의 역할에 중점을 두어 재해지역에서 자원이용과 이의 관리문제를 연구하였다. 1970년대 들어오면서 재해의 양상, 적응방법등이 연구되고, 또한 적응의 여러 비교연구가 있었으며, 사회성과 관련 사회학적 연구 접근과 다양한 레벨의 케이스 Study 또한 이루어졌다. 오늘날의 자연재해연구는 일반재해연구로 발전하여 핵반응, 각종산업.교통재해, 화학물질 및 환경오염문제, 각종 소음공해, 폭발물 사고 등 참으로 여러 종류의 사회문제가 재해연구의 대상이 되었고, 근래에는 약물중독, 성폭행, 그리고 복잡한 현대사회에서 제기되는 정신질환까지 일종의 재해문제로 다루어 지리학내에서 연구되고 있다. 이와같이 연구의 많은 변환.발전과 함께 처음 Academic한 연구로 시작된 재해문제 연구가 이에 관심을 같는 여러분야 즉, 경제.사회, 심리학자, 토지이용개발자, 보험, 은행, 부동산업자 재해와 관련있는 민간단체, 정부기관, 정책실행기관등이 참여하는 공동연구가 활발히 행하여지고 있다. 최근에는 "세계 자연재해 감소 10개년 계획"이라는 Program을 미국이 주동이 되어 국제적인 기구로 만들어 관심있는 여러국가의 과학자, 재해연구가, Engineer, 정부관계자들이 참여 서로 정보와 지식의 교환, 세계의 개발.재개발에 대한 계획, 재해감소의 교육훈련등 다채로운 Project을 가지고 세계 자연재해 감소를 위하여 공동연구의 노력을 하려는 움직임이다. 세계의 권위있는 재해통계에 의하면 한국이 매년 자연재해로 인하여 100만명당 1,000명이 희생되는 나라로 방글라대시, 이란, 중남미와 페루, 과태말라, 동남아시아의 뉴기니와 나란히 중진개발도상국으로 몇안되는 나라의 하나로 들어있는 것을 볼 때 유감이 아닐수 없다. 우리나라는 하루빨리 이러한 자연재해로부터 아까운 생명과 재산을 잃어버리고 있는 고통과 문제를 해결하려는 민간.정부차원에서 관심을 기울이고 우선 기본적인 연구의 기틀을 마련하는 제도적 장치와 분위기가 아쉽다고 않을 수 없다.와 분위기가 아쉽다고 않을 수 없다.

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A Case of Constitutional Trisomy 8 Mosaicism

  • Cho, Hee-Soon;Lee, Chae-Hoon;Kim, Kyoung-Dong;Lee, Eun-Sil
    • Journal of Yeungnam Medical Science
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    • v.22 no.2
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    • pp.241-246
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    • 2005
  • Constitutional trisomy 8 is a relatively rare aneuploidy; most identified cases are mosaic with a normal cell line. The phenotype is highly variable from apparently normal to severe disability. The proportion of abnormal cells is dramatically different between tissues and the severity of the phenotype is not directly related to the level of mosaicism. Therefore, it is very difficult to provide a definitive prognosis. We report here a case of constitutional trisomy 8 mosaicism with agenesis of the corpus callosum, congenital heart disease and micrognathia. The trisomy 8 cell line was not detected by prenatal cytogenetic study. This is the fourth reported case of constitutional trisomy 8 mosaicism in Korea.

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Path Analysis of General Government Debt to Individual Suicide (국가채무가 자살에 이르는 경로분석)

  • Lee, Yong-Hwan;Bang, Hee-Myung
    • The Journal of the Korea Contents Association
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    • v.19 no.8
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    • pp.535-543
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    • 2019
  • This study was conducted to find a pathway from the general government debt to GDP ratio(GDR) to the age standardized Suicide Rate(suicide rate). The variables used in this study are GDR, the consumer price index for living necessaries(CPIL), the household debt to GDP ratio(Household Debt), and suicide rate. The data used in this study were standardized data from 2001 to 2015 of Korean Statistical Information Service(KOSIS) and the path analysis was performed using the analysis IBM SPSS 22 and Amos. As a result of the path analysis, the path of GDR-CPIL-Household Debt-Suicide rate, and the direct of effect were in order 0.954, 0.904 and 0.675 were confirmed. The indirect effect of GDR on Household Debt is 0.862, GDR on Sucide Rate is 0.581, CPIL on Suicide Rate is 0.610. Neither of these indirect effect coefficient was significant(p>0.05).

A Study on the Effectiveness of Screening for Selective Breast Cancer Using Digital Mammography Centered on General Hospital (디지털 유방촬영술을 이용한 선별적 유방암 검진의 효용성에 대한 연구(2차 병원을 중심으로))

  • Kim, Hyeon-Jin
    • Journal of the Korean Society of Radiology
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    • v.15 no.2
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    • pp.147-152
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    • 2021
  • This study is a retrospective analysis of the results of tests at three general hospitals in Busan that perform mammography using digital mammography devices. There were 5,320 people in the study, and the results of their breast cancer screening were analyzed to verify the efficacy of breast cancer screening for digital mammography. The average age of patients who performed breast cancer screening was 57.7 years (range 30 to 87 years), and the cancer detection rate was 26, with 4.6 cases per 1,000 people. According to the cancer detection rate by risk factor in patients who conducted breast cancer screening, breast cancer was found in patients without underlying diseases more than in patients with underlying diseases. Additional ultrasound examinations show that the gastronomic rate identified is 3.6%, which is relatively very low compared to that of the Film-Screen system.