• The Journal of Korean Obstetrics and Gynecology
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• v.22 no.2
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• pp.172-188
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• 2009

Purpose: For mothers just delivered of a child, sanhupung(産後風) is a critical disease which can threaten their health. The symptoms of sanhupung were diverse and divided into pain symptoms, general symptoms, and neuropsychiatric symptoms. We tried to search for the relationship between sanhupung and somatization of postpartum depression. Methods: Analysis was carried out with materials concerning the postpartum depression and sanhupung. For the analysis, materials related with the issue of this study were searched at the Korea Education & Research Information Service, and Oriental medicine advanced searching. Results: 1. The range of period and symptoms of sanhupung has been broaden. The symptoms of sanhupung were divided into pain syndrome, general symptoms, and neuropsychiatric symptoms. 2. As the symptoms of postpartum depression might indicate not only physical symptoms but also mental disorder, more attention should be placed on wether the symptoms were involved in somatization of postpartum depression. Conclusion: The authors conclude that obstinate sanhupung that do not healed up and improve in symptoms have a relation to somatization of postpartum depression.

• The Journal of Korean Obstetrics and Gynecology
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• v.22 no.2
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• pp.94-118
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• 2009

Purpose: Gleditsiae spina (GS) has been used to treat patients with several diseases such as carbuncle, swelling and parasites. Recently GS is known to have anticancer activity in abdominal solid tumor, but the effects of GS on breast cancers is not clarified. For these reasons, we investigated effects of Gleditsiae spina (GS) on gene expression of human breast cancer cells. Methods: We investigated the effects of GS on proliferation of breast cancer cell line, MDA-MB-231. In addition, the genetic profile for the effect of GS on breast cancer cells was measured using microarray technique, and the functional analysis on these genes was conducted. Results: Total 1,434 genes were up-regulated and 2,483 genes down-regulated in the cells treated with GS. Genes induced or suppressed by GS were all mainly concerned with metabolic process, regulation of biological process and protein binding. The network of total protein interactions was measured using cytoscape program, and some key molecules that can be used for elucidation of therapeutical mechanism of medicine in future were identified. Conclusion: These results suggest possibility of GS as anti-cancer drug for breast cancer, and also suggest that related mechanisms are involved in regulation of intra-cellular metabolism in breast cancer cells.

• The Journal of Korean Obstetrics and Gynecology
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• v.22 no.3
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• pp.152-168
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• 2009

Purpose: The purpose of this study is to examine remedies suggested in the papers of ovarian cyst in Chinese Medicine Journals and to establish the further direction. Methods: The papers published between 1994 and 2009 in China Academic Journal were reviewed. Results: 1. It was on Bo-Ryu Enema that main focus of investigation was placed. A variety of randomized controlled trials and case series were found. As a result, a lot of proper manual arts and prescriptions were provided out of them. 2. Acupuncture is reported as significant in reducing the size of ovarian cyst and improving clinical symptoms, which covers electrical acupuncture, enlongated needle and moxibustion, burning acupuncture. 3. External application was verified as an effective therapy for the case of a combined treatment with oral medicine. 4. Modern medical equipments such as ultra short wave medical cure, TDP could improve the efficiency of traditional remedies like Bo-Ryu Enema, external application. Conclusion: It would be necessary to practically come up with a diversity of remedies besides oral decoction of medical ingredients, and establish standard of evidence of them.

• The Journal of Korean Obstetrics and Gynecology
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• v.22 no.1
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• pp.95-109
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• 2009

Purpose: This study was performed to determine the inhibitory effect of Sihosogansangagambang (SS) on melanin synthesis in B16F10 melanoma cells (B16F10). Methods: The inhibitory effects of Sihosogansangagambang on melanin synthesis were used by in vitro assay. To elucidate inhibitory effects of SS on melanin synthesis, we determined the melanin release in B16F10. And to investigate the mechanism of inhibitory effect of SS, we assessed the gene expression of tyrosinase, TRP-1, TRP-2 and ERK-1 in B16F10. Results: 1. SS decreased the release of melanin in B16F10 melanoma cells. 2. SS inhibited mushroom tyrosinase activity in vitro. 3. SS decreased the expression of tyrosinase, TRP-2 in B16F10 melanoma cells, but did not decreased the expression of TRP-1 in B16F10 melanoma cells. 4. SS decreased the expression of ERK-1 in B16F10 melanoma cells. Conclusion: From these results, it may be suggested that SS is possesed of the antimelanogenetic effects.

• The Journal of Korean Obstetrics and Gynecology
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• v.22 no.4
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• pp.205-214
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• 2009

Purpose: Adenomyosis is the disease caused by ingrowth of lining tissue into the uterine muscle. Final treatment of the disease is hysterectomy but there is a tendency to avoid surgical treatment if possible. And medication often results in relapse and it does not cure completely. This paper introduces the potential of oriental medical treatment for adenomyosis through a case study. Methods: A 31-year-old female patient, suffered from pelvic pain and metrorrhagia, was diagnosed with adenomyosis and uterine myoma. She was put on oriental medical treatment in the ○○ Oriental Hospital for almost three months. We applied herb-medication, acupuncture and moxibustion. Results: Overall condition including the symptoms was relieved after oriental medical treatment Conclusion: Oriental medical treatment alleviates chronic pelvic pain and has an effect against adenomyosis.

• The Journal of Korean Obstetrics and Gynecology
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• v.22 no.1
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• pp.203-230
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• 2009

Purpose: In order to know therapies used in the field of Obsterics & Gynecology of Oriental medicine. Methods: This survey investigated papers about clinical study, literature investigation for therapeutic methods and treatment reports published from 1999. 2${\sim}$2008. 11. Results: In the clinical studies, acupuncture is more frequently used than herbal medicine. But in the treatment reports, herbal medicine is most frequently used except some cases. Besides acupuncture and moxibustion was used frequently. In the treatment reports various acupuncture methods were used except vaginal bleeding or abdominal pain cases. Whole body acupuncture was used mainly. Pharmacopuncture, Sa-am Acupuncture, auricular acupuncture was also used frequently. And Dong's acupuncture, Hwa acupuncture was used sometimes. Moxibustion was tend to be used for dysfunctional uterine bleeding, menopausal disorder, urinary incontinence, vaginal bleeding or abdominal pain during pregnancy period, hyperemesis, recurrent miscarriage, postpartum disease, lochiorrhea. Also other treatment methods was used such as external therapy, aromatherapy, herbal retention enema, fumigation, electric lipolysis acupuncture, Chuna manual medicine, obesity management, acupuncture at uterus cervix, magnetic innervation therapy, exercise, cupping and physical therapy. Conclusion: These results suggests that acupuncture, moxibustion and herbal medicine are most frequent therapy in the field of Obsterics & Gynecology of Oriental medicine. And other therapy are used such as external therapy, aromatherapy, herbal retention enema, fumigation and so on.

• The Journal of Korean Obstetrics and Gynecology
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• v.37 no.2
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• pp.17-34
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• 2024

Objectives: The purpose of this study is to evaluate the quality of case reports published in the Journal of Korean Obstetrics and Gynecology from April 2019 to February 2024, compared with January 2015 to March 2019. Methods: Case reports were selected by searching from archive on the website of society of the Journal of Korean Obstetrics and Gynecology. The quality of the case reports were assessed based on CAse REport (CARE) guideline. Results: A total of 30 case reports was finally included for the assessment. Overall quality of reporting for case reports published from April 2019 to February 2024 was improved compared to one of previous study. However, the 4 items of CARE guidelines with an unreported rate of 50% or more - patient's perspective on interventions (96.67%), diagnostic challenges (93.33%), intervention adherence and tolerability (93.33%), adverse events (56.67%) - are items that require active description in future case reports. In addition, Keyword and timeline have more than 50% reported to be 'Not-sufficient' in both previous and present studies. So active efforts by researchers are needed to include 'Case report (or Case study)' in keywords, and to include intervention by period, symptom changes in a timeline. Conclusions: Despite the overall improvement in the quality of reporting in the Journal of Korean Obstetrics and Gynecology, efforts to improve the quality of case reports should be continued.

• The Journal of Korean Obstetrics and Gynecology
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• v.23 no.1
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• pp.124-135
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• 2010

Purpose: To report the patient with sciatic neuropathy after gynecologic laparoscopy, who improved by Traditional Korean Medical treatment and to study Traditional Korean Medicine(TKM) management of complications of gynecologic laparoscopy. Methods: A patient with sciatic neuropathy after gynecologic laparoscopy was managed with herbal medicine, acupuncture and moxibustion treatment. Results: After about 2 months treatment, patient's symptoms and signs were improved. TKM management was effective in recovery of neurologic complication after gynecologic laparoscopy. Conclusion: We need to actively participate in management of complications of gynecologic laparoscopy as primary or adjuvant therapy. And more study is needed for developing Traditional Korean Medical indication of complications of Gynecologic Laparoscopy.

• The Journal of Korean Obstetrics and Gynecology
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• v.22 no.1
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• pp.191-202
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• 2009

Purpose: This research is to investigate the needling Depth for Deqi based onone's age, weight, and the level of obesity and the different Deqi sensation in Chung-wan and Kwan-wan. Methods: We took a research on Deqi for the 123 patients who visited a local Korean Medicine clinic at random. The variants were the age, the weight, thetotal fat rate, the waist-hip rate, BMI, the weight size, and the Sasang constitution. Result: Older patients need more depth of Deqi in Chung-wan and Kwan-wan compared to the younger ones. The higher the level of obesity(weight, total body fat rate, the waist-hip rate, BMI) goes up, the more Deqi in Chung-wan and Kwan-wan goes deeply. As the level of obesity goes down in the order of Taeeum-in, Soyang-in, Soeum-in, the depth of Deqi also decreases in Chung-wan and Kwan-wan. Deqi in Chung-wan is the feeling of pressure around the acu-point, and Deqi in Kwan-wan is the feeling that it spreads out to the upper, lower, the right, and the left side of the acu-point. Conclusion: In case of Needling Depth for Deqi on Chung-wan and Kwan-wan, that increases or decreases as the age, the level of obesity(the physique), and the Sasang constitution changes.

• The Journal of Korean Obstetrics and Gynecology
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• v.22 no.2
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• pp.222-230
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• 2009

Purpose: This study intends to report the effects of Koong Gui Tang on Cold Hypersensitivity caused by acute and chronic Blood Deficiency. Methods: The patients having Cold Hypersensitivity were treated with oriental medicine including herbal medication therapy. Thereafter their health status was analyzed with their own empirical assessments and VAS. Results: After the series of medical treatment, Cold Hypersensitivity caused by acute and chronic Blood Deficiency has shown considerable improvement. Conclusion: This case study shows that Koong Gui Tang therapies are medically effective on Cold Hypersensitivity caused by acute and chronic Blood Deficiency.