• 대한통합의학회지
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• 제2권2호
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• pp.13-20
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• 2014

Purpose : The purpose of this study was to evaluate the influence of cognition and executive function by computer - based attention program in vascular dementia. Method : The subjects of this study, old man diagnosed with vascular dementia, 12 patients were picked up, who were agreed with this research and were having hospital care for 4 weeks at nursing care centers. Computer-based attention program was applied to vascular dementia. Cognitive function measured by a K-MMSE and executive function measured by ACL. The SPSS Ver. 18.0 statistical program was used for data processing. The significance level for statistical inspection was set as 0.05. Result : In comparison of cognitive function was not significantly correlated in the pre and post test and executive function was significantly correlated in the pre and post test. Conclusion : Therefore, the computer-based attention program is useful to improve the cognitive and executive function in elderly with vascular dementia.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2022년도 춘계학술대회
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• pp.394-395
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• 2022

Exergames are playing an important role in healthcare/rehabilitation. It has also been used to improve motivation among patients with reduced cognition. The purpose of this pilot study was to evaluate the feasibility of using augmented reality (AR) with game-based cognitive-motor training programs for executive function, restricted and repetitive behaviors (RRBs) in children with autism spectrum disorder. Sixteen children aged 6 -16 years were randomly allocated to the experimental group and control group. Outcome measures were performed before and after the intervention and included executive function, restricted and repetitive behavior. A satisfactory survey was conducted post-intervention. A statistically significant improvement was observed in working memory and cognitive flexibility in the experimental group (P<0.05). However, despite no statistical improvements in cognitive inhibition and four subscales of RRBs, promising changes were observed in all the subscales of the executive function and the behavioral outcomes. Parents appreciated the program and children enjoyed the interaction with the AR game-based training. The findings of this preliminary feasibility study showed that AR using Kinect v2 motion with a cognitive-motor game content can be used for children with autism. However, there is a need for conducting a large-scale study to evaluate his effectiveness on executive function and restricted and repetitive behaviors.

• 생물정신의학
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• 제14권1호
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• pp.61-67
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• 2007

Objectives : The purpose of this study was to test stage model in Traumatic Brain Injury(TBI) patients. According to the stage model, attention deficits which is basic stage in information processing lead to memory disturbance and subsequently affect higher-order cognitive function such as memory, decision-making, abstract thinking, and judgement related to executive function. Therefore, it was hypothesized that attention affect recall(retrieval efficacy) related to executive function mostly relative to other cognitive function, in TBI patients with low executive function. Methods : Participants were referred to a TBI clinic and then was rated on K-WAIS and Executive Intelligence Test(EXIT). Participants were divided into two groups according to Executive IQ(EIQ) score, which of high function group(N=67) was more than 80(above low average) and of low function group(N=52) was under 80 (under borderline). To test the stage model, using hierarchical regression analysis, recall(retrieval efficacy) was regressed on 3 subscales(attention, verbal, visuospatial scale) after controlling for IQ according to each group. Furthermore, the mediation effect of attention between retrieval efficacy and verbal, visuospatial score was analyzed. Results : In the low function group, only attention area predicted significantly recall(retrieval efficacy), indicating that lower attention were related to lower EIQ after controlling for IQ. In the high function group, no area predicted significantly retrieval efficacy. In the low function group, verbal and visuospatial scale did not predicted significantly retrieval efficacy, indicating that there was no evidences supporting the mediation model. Conclusion : Only attention affect retrieval efficacy in TBI patients with low executive function. But, the mediation effect of attention between retrieval efficacy and verbal and visuospatial scale was not tested in the low function group. These results implied that stage model was tested partially. In treating cognitive deficit in TBI patients, it is necessary to develop cognitive rehabilitation program based on stage model. Furthermore, it is necessary to necessary to test mediation model in the future study.

• 생물정신의학
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• 제13권3호
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• pp.191-201
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• 2006

Objectives : The purpose of this study was to investigate whether the cognitive functions would be correlated with psychotic symptoms and whether antipsychotic treatments would affect the cognitive functions after 8 weeks. Methods : The thirty-five schizophrenic patients were conducted in this study. The psychopathology was measured using PANSS. The memory function, executive function, and sustained attention were measured using Memory Assessment Scale(MAS), Wisconsin Card Sorting Test(WCST), and Vigilance(VIG) and Cognitrone(COG) in Vienna Test System. After 8 weeks of antipsychotic treatment, we retested the cognitive tests. Results : 1) The cognitive tests after the 8 week's treatment showed significant improvements in memory and executive function in the schizophrenic patients. On the other side, sustained attention did not show improvement. 2) The change of PANSS were correlated with perseverative response, perseverative error and total correct in WCST at baseline. WCST scores at baseline were correlated with negative symptoms, but not positive ones. Conclusion : These study suggests that 1) the impaired sustained attention could be a vulnerability marker in schizophrenia, 2) memory & executive function deficit could be reversible after treatment, and 3) medication might have a benefit in improving the cognitive functions in schizophrenia. Furthermore, the data supports that the better premorbid executive function was, the more favorable was the treatment response in schizophrenic patients. Finally, this study indicates that executive function might be an index of treatment improvement.

• 재활치료과학
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• 제10권3호
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• pp.23-41
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• 2021

목적 : 본 연구는 노인을 대상으로 한 동시적 이중과제 훈련을 적용하였을 때 실행기능의 효과를 알아본 연구를 분석하는 것을 목적으로 한다. 연구방법 : PubMed, EMBASE, CoChrane, Web of Science, RISS를 이용하여 지난 10년간 출판된 논문을 검색하였고, 선정 및 배제 기준을 통해 최종 7편의 논문을 선정하였다. 선정 논문에 대한 PEDro 질적평가와 메타분석을 시행하였다. 결과 : 선정된 7편의 논문은 모두 무작위 대조군 설계로, PEDro Scale 7점 이상의 높은 편에 속하였다. 이중과제 훈련의 실행기능 효과를 보기 위한 평가도구로 4편의 문헌에서 선로잇기검사(Trail Making Test)를 사용하였고, 2편에서 색선로잇기검사(Color Trail Test)를 사용하였으며, 3편에서 스트룹검사(Stroop test)를 사용하였다. 메타분석을 실시한 결과 전체적인 실행기능의 향상은 0.38로 작은효과크기를 보였으며, 선로잇기검사와 색선로잇기검사는 0.37, 스트룹검사는 0.34로 작은효과크기를 보였다. 전체적인 실행기능 효과와 선로잇기검사, 색선로잇기검사의 효과크기만 통계학적으로 유의하였다(p<0.05). 결론 : 본 연구를 통해 이중과제 훈련이 노인의 실행기능 향상에 효과적임을 확인하였지만, 이중과제 훈련의 효과를 높이기 위해서는 훈련의 난이도 설정이 중요하며, 실행기능을 평가하는 다양한 평가도구와 실제 이중과제 조건에서의 수행도를 평가하는 평가도 동시에 이루어져야 함을 알 수 있었다. 이는 향후, 노인들의 실행기능 향상 훈련을 하는데 적절한 중재방법으로 사용될 수 있으며, 치매 발현을 늦추는데 도움이 될 것이라 사료된다.

• 생물정신의학
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• 제13권2호
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• pp.82-94
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• 2006

Objectives : In order to explore effects of board-game therapy for cognitive rehabilitation in patients with schizophrenia, we investigated the change of executive cognitive function over a 2-month period of board-game therapy in patients with schizophrenia. Methods : Two groups of chronic schizophrenic inpatients were participated in this study. One group(n=21) were treated with board-game therapy for 2 months and the other control group(n=19) were not treated. For the evaluation of the executive cognitive function, a Wisconsin Card Sorting Test(WCST) was administered before and after the introduction of the board-game therapy. PANSS score change was also evaluated. Result : At the beginning of this study, there was no significant difference in performance of cognitive function tests, demographical data or clinical severity between both patient groups. After 2 months of treatment with the board-game therapy, the board-game therapy group showed significant improvements of executive cognitive function without any significant change of their schizophrenic symptoms. On the contrary, there was no change in control group. Conclusion : This study showed that a board-game therapy is effective for the enhancement of executive cognitive function in patients with chronic schizophrenia. A board-game therapy could be introduced with ease into psychiatric fields, such as inpatients' or outpatients' clinic wards and day hospital. Our result indicates that the board-game therapy is a promising tool for the enhancement of cognitive function, especially executive cognitive function and helpful for cognitive rehabilitation for schizophrenic patients.

• 아동학회지
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• 제34권5호
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• pp.99-114
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• 2013

This study examined the relationships between children's cool executive function(cool EF), hot executive function(hot EF) and self-regulation according to the developmental changes. Children aged 3-5 years (N = 104) participated in this study. The participants completed cool and hot EF tasks and teachers reported on the children's cognitive regulation, emotional regulation, and behavioral regulation by means of questionnaires. The results indicated that cool EF and hot EF had different developmental patterns according to different age groups. High levels of cool/hot EF predicted better abilities in terms of cognitive, emotional, and behavioral regulation respectively. The relationship between coo/hot EF and cognitive/behavioral regulation were moderated by age, except in the case of emotional regulation. This paper also offers a detailed discussion of results and recommendations for future studies.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제26권1호
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• pp.45-51
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• 2015

Objectives : Children with attention-deficit hyperactivity disorder (ADHD) have been shown to display more inhibitory deficits and executive function deficits. This study investigated the treatment effects of neurofeedback (NF) training on executive function by comparing the results of neuropsychological tests of the trained children at pre- and post-training. Methods : Fifteen children with ADHD, aged 6 to 14 years, participated in the study. The NF treatment consisted of slow cortical potential (SCP) training and these sessions took place once a week. The ADHD children performed 20 sessions of NF training within 6 months. Pre-training and post-training assessments encompassed Continuous Performance Test (CPT), Stroop Test, Children's Color Trails Test I&II (CCTT) and Wisconsin Card Sorting Test (WCST). Results : Patients receiving NF training showed significant improvement in visual commission error and standard deviation of auditory response time on CPT ; and total errors on WCST. But there was no significant improvement in the Stroop test and CCTT. Conclusion : SCP training using NF improves the self-regulatory capacities and impulsivity in ADHD patient, especially impulsivity in visual stimulation tasks. This study showed evidence of clinical efficacy of NF on executive function in ADHD.

• 말소리와 음성과학
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• 제15권3호
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• pp.45-52
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• 2023

Previous studies have established a role for cognitive differences in explaining variability in speech processing across individuals. In the case of perceptual cue weighting in the context of a sound change, studies have produced conflicting results regarding the relationship between executive function and the use of redundant cues. The current study aimed to explore this relationship in acoustic cue weighting during speech production. Forty-one Korean-speaking children read a list of stop-initial words and completed two tests that assess executive function, i.e., Dimensional Change Card Sorting (DCCS) and digit n-back. Voice onset time (VOT) and fundamental frequency (F0) were measured in each word, and analyses were carried out to determine the extent to which children's executive function predicted their use of both informative and less informative cues to the three pairs comprising the Korean three-way stop laryngeal contrast. No evidence was found for a relationship between cognitive ability and acoustic cue weighting in production, which is at odds with previous, albeit conflicting, results for speech perception. While this result may be due to the lack of task demands in the production task used here, it nevertheless expands the empirical ground upon which future work in this area may proceed.

• Clinical and Experimental Pediatrics
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• 제63권6호
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• pp.219-225
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• 2020

Background: There is increasing concern that moderate preterm (32-33 weeks' gestation) and late preterm (34-36 weeks' gestation) birth may be associated with minor neurodevelopmental problems affecting poor school performance. Purpose: We explored the cognitive function, cognitive visual function, executive function, and behavioral problems at school age in moderate to late preterm infants. Methods: Children aged 7-10 years who were born at 32⁺⁰ to 36⁺⁶ weeks of gestation and admitted to the neonatal intensive care unit from August 2006 to July 2011 at the National Health Insurance Service Ilsan Hospital were included. We excluded children with severe neurologic impairments, congenital malformations, or chromosomal abnormalities. Neuropsychological assessments consisted of 5 neuropsychological tests and 3 questionnaires. Results: A total of 37 children (mean age, 9.1±1.2 years) participated. The mean gestational age at birth was 34.6±7.5 weeks, while the mean birth weight was 2,229.2±472.8 g. The mean full-scale intelligence quotient was 92.89±11.90; 24.3% scored between 70 and 85 (borderline intelligence functioning). An abnormal score was noted for at least one of the variables on the attention deficit hyperactivity disorder diagnostic system for 65% of the children. Scores below borderline function for executive quotient and memory quotient were 32.4% and 24.3%, respectively. Borderline or clinically relevant internalizing problems were noted in 13.5% on the Child Behavior Check List. There were no significant associations between perinatal factors or socioeconomic status and cognitive, visual perception, executive function, or behavior outcomes. Conclusion: Moderate to late preterm infants are at risk of developing borderline intelligence functioning and attention problems at early school age. Cognitive and executive functions that are important for academic performance must be carefully monitored and continuously followed up in moderate to late preterm infants.