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검색결과 2,654건 처리시간 0.03초

랜덤 포리스트를 이용한 비제어 급성 출혈성 쇼크의 흰쥐에서의 생존 예측 (A Survival Prediction Model of Rats in Uncontrolled Acute Hemorrhagic Shock Using the Random Forest Classifier)

  • 최준열;김성권;구정모;김덕원
    • 대한의용생체공학회:의공학회지
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    • 제33권3호
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    • pp.148-154
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    • 2012
  • Hemorrhagic shock is a primary cause of deaths resulting from injury in the world. Although many studies have tried to diagnose accurately hemorrhagic shock in the early stage, such attempts were not successful due to compensatory mechanisms of humans. The objective of this study was to construct a survival prediction model of rats in acute hemorrhagic shock using a random forest (RF) model. Heart rate (HR), mean arterial pressure (MAP), respiration rate (RR), lactate concentration (LC), and peripheral perfusion (PP) measured in rats were used as input variables for the RF model and its performance was compared with that of a logistic regression (LR) model. Before constructing the models, we performed 5-fold cross validation for RF variable selection, and forward stepwise variable selection for the LR model to examine which variables were important for the models. For the LR model, sensitivity, specificity, accuracy, and area under the receiver operating characteristic curve (ROC-AUC) were 0.83, 0.95, 0.88, and 0.96, respectively. For the RF models, sensitivity, specificity, accuracy, and AUC were 0.97, 0.95, 0.96, and 0.99, respectively. In conclusion, the RF model was superior to the LR model for survival prediction in the rat model.

폐목재(廢木材) 활용(活用)을 위한 플라즈마 처리(處理) 효과(效果)에 대한 연구(硏究) (A Study on Effect of Plasma Treatment for Waste Wood Application)

  • 김미미;임중연
    • 자원리싸이클링
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    • 제22권2호
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    • pp.18-21
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    • 2013
  • 본 실험에서는 상압플라즈마에 의한 목분의 표면개질에 대해 조사하였다. 복합재는 목분과 폴리프로필렌을 이용하여 제작되었다(목분 : 폴리프로필렌=55wt% : 45wt%). 상압플라즈마는 carrier gas로 헬륨과 HMDSO를 모노머로 사용하였고 3 KV, $17{\pm}1$KHz, 2 g/min의 조건에서 처리하였다. 폐목분의 인장강도는 상압플라즈마 처리를 통해 18.5 MPa에서 21.2 MPa로 14.6% 증가하였고 단일수종목분의 경우에도 21.5 MPa에서 23.4 MPa로 8.8% 증가하였다. 이것으로 상압플라즈마 처리는 목분의 표면을 개질하여 폴리프로필렌과의 계면결합력을 증가시켜주는 것을 확인하였다.

재사용 가능한 컴포넌트 기반의 임베디드 시스템 통합 프로토타이핑 기법 (Embedded System Integrated Prototyping Mechanism Based on Reusable Component)

  • ;이정배;임기욱;황영섭;김영진;안성순
    • 정보처리학회논문지A
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    • 제16A권3호
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    • pp.199-208
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    • 2009
  • 최근에 임베디드 시스템 개발자들을 위한 프로토타이핑 시스템 도구가 시장에 많이 출시되고 있다. 일찍부터 임베디드 시스템 설계에서 사용자의 요구사항을 분석하고 사용자 편의 인터페이스를 만드는데 있어서 프로토타입은 중요한 요소이다. 프로토타이핑 도구는 다음과 같이 Physical Prototyping (PP), Virtual Prototyping (VP), Modeling Prototyping (MP) 3가지로 나눌 수 있다. 이러한 프로토타이핑 기술을 통합하면 개발에 소모되는 비용내지 시간이 절약되므로써 시장진입시점이 빨라지고 제품의 경쟁력이 향상된다. 하지만 이러한 프로토타이핑을 통합하는데 있어서 여러가지 문제점이 존재한다. 본 논문에서는 여러 프로토타이핑 도구를 통합하는데 있어서 Javabean, ActiveX등과 같이 유연하고 재사용성이 용의한 컴포넌트를 이용하여 문제점을 해결하는 모습을 보여준다. 이러한 기술은 여러 임베디드 시스템을 개발시 재사용성과 유연성을 통한 편리성을 가질 수 있다.

A Novel Separator Membrane for Safer Lithium-ion Rechargeable Batteries

  • Lee, Sang-Young;Kim, Seok-Koo;Hong, Jang-Hyuck;Shin, Byeong-Jin;Park, Jong-Hyuck;Sohn, Joon-Yong;Jang, Hyun-Min;Ahn, Soon-Ho
    • 한국고분자학회:학술대회논문집
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    • 한국고분자학회 2006년도 IUPAC International Symposium on Advanced Polymers for Emerging Technologies
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    • pp.69-70
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    • 2006
  • In lithium-ion batteries, separator membrane's, main role is to physically isolate a cathode and an anode while maintaining rapid transport of ionic charge carriers during the passage of electric current. As far as battery safety is concerned, the electrical isolation of electrodes is most crucial since unexpected short-circuits across the membrane induces hot spots where thermal runaway may break out. Internal short-circuits are generally believed to occur by protrusions on the electrode surface either by unavoidable deposits of metallic impurities or by dendritic lithium growth during battery operation. Another cause is shrinkage of the separator membrane when exposed to heat. If separator membrane can be engineered to prevent the internal short-circuit, it will not be difficult to improve lithium-ion batteries' safety. Commonly the separators employed in lithium-ion batteries are made of polyethylene (PE) and/or polypropylene (PP). These materials have terrible limitations in preventing the fore-mentioned internal short-circuit between electrodes due to their poor dimensional stability and mechanical strength. In this study we have developed a novel separator membrane that possesses very high thermal and mechanical stability. The cells employing this separator provided noticeable safety improvement in the various abuse tests.

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폴리프로필렌 표면 위에 폴리비닐피롤리돈의 플라즈마 유도 그래프트 공중합 (Plasma-Induced Grafting of Poly(N-vinyl-2-pyrrolidone) onto Polypropylene Surface)

  • 지한솔;정시인;허호;최호석;김재하;박한오
    • 폴리머
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    • 제36권3호
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    • pp.302-308
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    • 2012
  • 본 연구의 목적은 대기압 플라즈마 처리된 평판형 폴리프로필렌(polypropylene, PP) 필름 표면 위에 폴리비닐피롤리돈(poly($N$-vinyl-2-pyrrolidone), PVP)을 그래프트 공중합시키기 위한 최적 조건을 찾는데 있다. 대기압 플라즈마 처리 조건은 RF power 200W, Ar 유속 6 LPM, 처리시간 30초, 처리 후 노출시간은 5분으로 고정하였다. 그래프트 공중합에서는 중합 시간, 중합 온도, 비닐피롤리돈($N$-vinyl-2-pyrrolidone, NVP) 농도의 조건을 각각 달리하여 표면 그래프트도의 변화를 조사하였다. 그 결과, 중합 시간 6시간, 중합 온도 $90^{\circ}C$, NVP 농도 40%에서 가장 높은 그래프트도를 나타내었다. ATR-FTIR, X-ray photoelectron spectroscopy(XPS), SEM 분석을 통해서도 PVP의 도입을 확인할 수 있었다.

기능성 엘라스토머를 이용한 선형 폴리페닐렌 설파이드의 개질 및 그 특성 (Modification of Linear Polyphenylene Sulfide with Functional Elastomers and Its Properties)

  • 김성기;홍인권;이상묵
    • 폴리머
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    • 제37권3호
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    • pp.399-404
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    • 2013
  • 장기내열성과 파단신율이 우수한 블렌드 수지를 개발하고자 polyphenylene sulfide(PPS)에 7종류의 elastomer를 용융혼합하여 그 가능성을 조사해 보았다. PPS/elastomer(90/10, 80/20, 70/30) 블렌드를 제조한 후 시험편을 압축성형 또는 sheet를 제조하여 capillary rheometer, UTM, impact tester, SEM 등으로 유변학적 거동, 기계적 특성 및 모폴로지를 측정하였고 오븐에서 일주일간 열을 가한 후 다시 기계적 특성을 측정하였다. 열을 가하기 전의 인장강도는 elastomer 종류에 관계없이 비슷하였고 파단신율은 m-EVA의 경우가 가장 큰 값을 보였다. Elastomer 첨가량을 증가시킴에 따라 신율이 증가하였는데 30 wt%정도 첨가 시 박리가 발생하였다. 오븐테스트 이후에는 인장 강도는 더 증가한 반면에 신율은 급격히 감소하였다. 상기의 elastomer들이 PPS와 부분적인 상용성이 있는 것으로 보이는 바 소량의 elastomer 첨가 만으로도 PPS 가공과 관련된 여러 문제 등을 해결할 수 있어 다양한 그레이드의 개발에 적극 활용될 수 있을 것으로 기대된다.

벼 직파재배(直播栽培)의 잡초발생(雜草發生) 생태(生態)와 효과적(效果的)인 방제법(防除法) (Weed Ecology and Effective Weed Control Technology in Direct-Seeded Rice)

  • 김순철
    • 한국잡초학회지
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    • 제12권3호
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    • pp.230-260
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    • 1992
  • The paper was reviewed the research results on weed dynamics and effective control methods in direct-seeded rice crop. Direct seeding method resulted in drastic increment of weed growth compared to transplanting method and also changed in troublesome weed flora. Two to three fold more weeds were harvested at the direct seeded rice and weed flora of dominant species shifted toward $C_4$type grass weeds. Some of the important troublesome weeds in direct seeded rice were Echinochloa crus-galle, Oryza saliva ssp spontanea, Leptochloa chinensis. Setaria viridus. Digitaria adsendens, Sesbania exaltata, Aeschynomene indica, Algae, etc. Yield loss due to weed competiton was about 40-60% for water-seeded and about 70-100% for dry-seeded rice while these for transplanted rice were about 25-35% for mechanical transplanting and about 10-20% for manual transplanting, respectively. Integrated weed management concept was neede to approach weed control effectively. Several cultural technologies were very effective to suppress the weed growth. These were tillage operation, water management, seeding date and seeding rate. Crop residues of barley, rice, wheat, oat and italian ryegrass were also effectivly suppressed the paddy weeds particularly to Potamogeton distiuctus, a perennial broadleaf weed. A pathogen of Epicoccosorus nematosporus identified from Eleocharis kuroguwai was an excellent potential bioagent to control the most troublesome perennial sedge weed of E. Kuroguwai without arising any detrimental effect. The herbicidal efficacy of this pathogen was as high as bentazon herbicide. Plant growth regulator of paclobutrazol (pp-333) was another possible alternative to reduce the herbicide use. In current, herbicide exhibited the most conspicuous results to control weeds in direct-seeded rice even though the application technologies were not fully established. Recommendations for herbicide application were suggested for in both water-and dry-seeded rice in USA, Japan and Korea, respectively. To make better and comprehensive recommendations further studies on weed ecology and herbicide development were emphasized.

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pphotoemission study of rare-earth metal(Eu) on the CdTe(110) surface

  • Kwanghyun-Cho;Oh, J.H.;Chung, J.;K.H.ppark;Oh, S.J.
    • 한국진공학회:학술대회논문집
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    • 한국진공학회 1994년도 제6회 학술발표회 논문개요집
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    • pp.43-43
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    • 1994
  • We studied chemical reactio of Eu metal on the in situ cleaved CdTe(110) surface by pphotoemission sppectroscoppy using synchrotron radiation. The chamber was maintained with base ppressure $\leq$2${\times}$10-10 mb during the expperiment. The expperiment was carried out in pphoton Factory in Jappan. Core level pphotoemission sppectroscoppy was carried out with Al K${\alpha}$ Line. The CdTe simiconductor was determined to be pp-typpe with low dopping concentration from Hall measurement. We found that there are two reacted pphases of Te with Eu (related to divalent Eu and trivalent Eu, resppectively) from least square fitting of Te 4d sppectra, but three is no indication of Cd reaction. Trivalent Eu exists after roughly one monolayer depposition (600 sec. depposition time is considered as one monolayer), which is also observed at Eu 3d core level sppectra. Overlayer Eu is metallized after roughly 2 monolayers depposition, as can be deduced from the fact that metallic edge near Fermi level begins to appear. The intensity of core-level of Te decreases expponentially at the initial stage (near one monolayer) and after one monolayer depposition it decreases more slowly due to Te out-diffusion. We categorized the growth mode of Eu on CdTe as S-K growth mode (cluster formation after one monolayer deppisition) from the relative intensity pplot of Te 4d normalized to the cleaved surface. At cleaved surface band bending is already established due to surface defects. At first 100 sec. depposition time the shift toward lower binding side by 0.6 eV is found at all core level sppectra of all elements in semiconductor. This shift is considered as the re-adjustment of surface Fermi level to the pposition induced by Eu metal (0.2 eV above the valence band maximum).

백복령 첨가에 따른 식빵의 이화학적 특성 변화 (Changes on the Characteristics of Bread Added with the powder of Poria cocos Wolf)

  • 신길만;박종열
    • 한국식품저장유통학회지
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    • 제15권2호
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    • pp.231-235
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    • 2008
  • 백복령분말의 첨가량에 따른 밀가루 반죽의 품질특성에 미치는 영향을 알아보기 위하여 백복령분말을 $0{\sim}5%$의 비율로 첨가하여 식빵의 이화학적 특성을, 비교 분석하였다. 복령의 일반성분 함량은 수분 함량은 7.67%이었고, 조단백질 함량은 0.61% 나타났고, 조지방 함량은 0.58%로 나타났다. 조회분 함량은 0.32%이었고, 조섬유 함량은 0.30%로 나타났다. 백복령분말을 첨가한 밀가루의 호화도(RVA)는 백복령분말의 첨가량이 증가함에 따라 호화개시온도와 최고점도는 감소하였으며 breakdown은 백복령분말의 첨가량이 증가함에 따라 증가하였다. gluten 함량과 반죽팽창력은 모두 백복령분말 첨가량이 증가할수록 유의하게 증가하였다. 색도는 백복령의 첨가량이 증가할수록 L값은 낮아졌으며 a값과 b값은 증가하였다.

마황부자세신탕(麻黃附子細辛湯)의 각 구성약물별 항산화 및 항염 효능에 관한 연구 (Study on Antioxidant and Anti-inflammatory Effects of Components of Mahwangbujaseshin-tang)

  • 최철우;오민석
    • 한방재활의학과학회지
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    • 제24권4호
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    • pp.15-28
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    • 2014
  • Objectives This study was carried out to find out the Antioxidant and Anti-inflammatory Effects of Components of Mahwangbujaseshin-tang in LPS-Stimulated RAW264.7 Macrophages. Methods There are 5 experimental groups. ; normal, control, EH (Ephedrae Herba), ALRP (Aconiti Lateralis Radix Preparata) and AR (Asiasari Radix). The extract of EH, ALRP and AR ($100{\mu}g/ml$) was added to each group. We examined cytotoxicity, total phenolic contents, DPPH and ABTS free radical scavenging activity, Intracellular ROS (reactive oxygen species) production, NO (Total Nitric oxide), iNOS (inducible nitric oxide synthase), PGE2 (prostaglandin E2), COX-2 (cyclooxygenase-2), $IL-1{\beta}$ ($interleukin-1{\beta}$), IL-6 (interleukin-6), $TNF-{\alpha}$ (tumor necrosis factor-${\alpha}$), MMP-9 (matrix metalloproteinase-9), TIMP-1 (tissue inhibitor of metalloproteinase-1) and HO-1 (heme oxygenase-1) expression level. Results 1. Total phenolic contents of EH were in the highest level. 2. DPPH and ABTS free radical scavenging activity of EH was in the highest level. 3. ROS production was significantly decreased in AR. 4. NO production was significantly decreased in EH, ALRP, AR and iNOS expression was decreased in EH, AR. 5. PGE2 and COX-2 expression was decreased in EH, AR. 6. $IL-1{\beta}$ production was significantly decreased in EH, AR and IL-6 production was significantly decreased in AR. $TNF-{\alpha}$ production was significantly decreased in ALRP, AR. 7. MMP-9 and TIMP-1 production were significantly decreased in EH. 8. HO-1 expression was significantly increased in EH. 9. With simultaneous usage of SnPP which is expression inhibitor of HO-1, NO, $IL-1{\beta}$, IL-6 and $TNF-{\alpha}$ production were partially increased in EH, ALRP, AR. Conclusions According to this study, Components of Mahwangbujaseshin-tang have anti-oxidants and anti-inflammation effects in LPS-Stimulated RAW264.7 Macrophages.