• Nuclear Engineering and Technology
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• 제42권5호
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• pp.600-607
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• 2010

Rhenium-186, having a half-life of 90.64 h, is an important radionuclide, used in metabolic radiotherapy and radio immunotherapy. $^{186}Re$ hydroxyethylidene diphosphonate (HEDP) is a new compound used for the palliation of painful skeletal metastases. Its production is achieved via charged-particle-induced reactions; the data are available in EXFOR library. For the work discussed in this paper, production of $^{186}Re$ was done via $^{nat}W(p,n)^{186}Re$ nuclear reaction. Pellets of $^{nat}W$ were used as targets and were irradiated with 15, 17.5, 20, 22.5, 25 MeV proton beams at 5 ${\mu}A$ current. The radiochemical separation was performed by the ion exchange chromatography method. The production yield achieved at 25 MeV was 1.91 $MBq{\cdot}{\mu}A^{-1}{\cdot}h^{-1}$. Excitation functions for the $^{186}Re$ radionuclide, via $^{186}W(p,n)^{186}Re$ and $^{186}W(d,2n)^{186}Re$ reactions were calculated by ALICE-ASH and TALYS-1.0 codes to validate and fit the experimental data and to obtain a recommended set of data for $^{186}W(p,n)^{186}Re$ reaction. Required thickness of the targets was obtained by SRIM code for each reaction.

• 동의생리병리학회지
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• 제25권2호
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• pp.294-299
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• 2011

The purpose of this study is to investigate effects of Red Ginseng-Ejung-tang (RE) on nitric oxide (NO) and hydrogen peroxide production in RAW 264.7 mouse macrophages induced by lipopolysaccharide (LPS). Cell viability was measured by modified MTT assay. NO production was measured by Griess reagent assay. Hydrogen peroxide production was measured by dihydrorhodamine 123 (DHR) assay. RE did not show cell toxicity against RAW 264.7 for 24 hr incubation at the concentrations of 10, 25, 50, 100, and $200{\mu}g/mL$ in RAW 264.7. RE significantly inhibited NO production for 24 hr incubation at the concentrations of 10, 25, 50, and $100{\mu}g/mL$ in RAW 264.7 (P < 0.05). RE significantly inhibited the LPS-induced production of NO for 24 hr incubation at the concentrations of 10, 25, 50, and $100{\mu}g/mL$ in RAW 264.7 (P < 0.05). RE significantly inhibited the LPS-induced production of hydrogen peroxide for 16, 24, 40, 48, 64, and 72 hr incubation at the concentrations of 50, 100, and $200{\mu}g/mL$ in RAW 264.7 (P < 0.05). These results suggest that RE has anti-inflammatory property related with its inhibition of NO and hydrogen peroxide production in LPS-induced macrophages.

• 대한지리학회지
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• 제39권5호
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• pp.768-785
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• 2004

주택에 관한 제도적 접근을 이론적 배경으로 한 이 논문은 1980-1990 년대 한국의 주택 생산 및 분배구조, 그리고 주택 시스템을 연구하였다. 더 나아가 이 논문은 한국적 맥락에서 주택 공간의 생산 및 재생산에 주택 에이젼트들이 어떠한 역할을 하였는지, 그리고 그들간의 역학관계는 어떠하였는지를 연구 주제로 하여 한국주택 정책의 특징들을 분석하였다. 주택 시장 및 도시 주거 구조에 관한 제도적 접근의 연구 초점은 바로 주택에 에이젼트들간의 역학 관계 및 갈등의 맥락에서 도시 토지 및 주택 시장의 제도적 구조를 분석하는 것이다. 주택 에이젼트의 역할, 주택 정책. 그리고 주택 관련 제도가 결정적 인자로 작용하는 한국 도시 주택 (재)생산 및 분배 구조 분석에는 주택에 관한 제도적 접근이 매우 유용하다.

• Journal of Microbiology and Biotechnology
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• 제10권1호
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• pp.107-110
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• 2000

Elicited cells with methyl jasmonate continued to produce benzophenanthridine alkaloids throughout medium changes in suspension cultures of Eschscholtzia californica. Large increases in alkaloid production were observed by re-elitations with medium changes. The total alkaloid production increased during the successive elicitation steps reaching a maximum level on the 4th elicitation. The highest total alkaloid produced was 250 mg/I, which was 20fold higher than that of the single elicitation and 4-fold higher than that of the normal culture without elicitation. The large increases in alkaloid production in successive re-elicitations with medium changes are believed to be caused by the accumulation of the signal transduction compound, jasmonate.

• 한국건설관리학회:학술대회논문집
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• 한국건설관리학회 2001년도 학술대회지
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• pp.416-421
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• 2001

국내 철근 콘크리트 공사는 철근현장가공조립을 주로 하고있는데 철근공사는 거푸집공사와 더불어 건축물의 구조적 안정성과 내구성 및 공기에 가장 큰 영향을 미치고 있는 공사이다. 이와 같은 철근현장가공조립의 프로세스를 린 생산원리를 적용하여 가치흐름분석을 하였다. 가치흐름분석은 가치분석과 가치흐름맵핑을 통해서 건설프로세스 상의 가치창출작업과 비 가치창출작업을 분석하였다 그 결과 비 가치창출 작업으로 인한 낭비로 많은 작업 단계와 인력, 장비, 자재, 시간 등이 낭비되고 있었다. 또한 밀어내기 생산(Push-driven Production)으로 과잉생산을 하는 등 생산의 낙후성이 조사되었다. 이러한 프로세스상의 문제점을 개선하기 위해 이 연구에서는 부가가치를 창출하는 가치창출 작업을 최대화하고, 비 가치창출작업을 최소화하여 낭비요소를 제거하는데 목적이 있다. 특히 진행간 재고를 최소화하여 흐름생산(Flow Production)과 당김생산(Pull-driven Production)이 될 수 있도록 하였다.

• 산업경영시스템학회지
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• 제20권43호
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• pp.17-24
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• 1997

This research suggests an approach to reduce the physical distribution cost of production by analyzing data from real situations. The proposed approach re-layouts facilities according to the SLP(Systematic Layout Planning) method. An application result showed that the production lead time was reduced by 24% and the payoff period for facility re-layout was about ten months.

• 한국정보통신학회논문지
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• 제22권9호
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• pp.1214-1219
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• 2018

2017년 현재 수많은 VR콘텐츠가 소개됨으로써 대중들의 VR에 대한 관심과 다양한 기술이 발전을 하고 있다. VR 콘텐츠는 $360^{\circ}$실사 촬영 제작환경의 어려움으로 인해 게임과 인터렉티브라는 장르에 편중되어 있는 것 또한 사실이다. 실사촬영에서의 조명은 영상 미학적 차원에서 중요한 요소 중에 하나이며 특정 캐릭터의 내적 표현 부분에서도 조명의 역할이 매우 중요하다. 실사 기반의 $360^{\circ}$VR콘텐츠는 조명설정에 따라 노출에 대한 부분과 제작환경의 어려움으로 인해 많은 문제점을 가지고 있다. 따라서 본 논문은 실사 촬영된 영상데이터를 기반으로 리라이팅 기술을 이용하여 실사 이미지의 양안시차에 3차원 정보 값을 생성한다. 생성된 3차원 정보 값은 뎁스 맵으로 변환하는 기술과 3D 공간에서 형성된 면에 가상의 조명을 설치하여 리라이팅 기술을 접목한다. 실제 조명과 가상의 조명의 영상데이터의 결과 이미지를 비교분석하여 리라이팅의 기술을 VR제작 파이프라인에 적용하여 조명 노출에 대한 문제점을 해결하고자 한다.

• Asian-Australasian Journal of Animal Sciences
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• 제14권8호
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• pp.1110-1117
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• 2001

Responses of the rumen fungus, Neocallimastix frontalis RE1, to long chain fatty acid (LCFA) were evaluated by measuring gas production, filter paper (FP) cellulose digestion and polysaccharidase enzyme activities. LCFA (stearic acid, $C_{18:0}$; oleic acid, $C_{18:1}$; linoleic acid, $C_{18:2}$ and linolenic acid, $C_{18:3}$) were emulsitied by ultrasonication under anaerobic condition, and added to the medium. When N frontalis RE1 was grown in culture with stearic, oleic and linoleic acid, the cumulative gas production, gas pool size, FP cellulose digestion and enzymes activities significantly (p<0.05) increased at some incubation times(especially, exponential phases of fungal growth, 48~120 h of incubation) relative to that for control cultures. However, the addition of linolenic acid strongly inhibited all of the investigated parameters up to 120 h incubation, but not after 168 and 216 h of incubation. These results indicated that stearic, oleic and linoleic acids tended to have great stimulatory effects on fungal cellulolysis, whereas linolenic acid caused a significant (p<0.05) inhibitory effects on the cellulolysis by the rumen fungus. These results are the first report of the effect of LCFAs on the ruminal fungi. Further research is needed to identify the mode of action of LCFAs on fungal strains and to verify whether or not ruminal fungi have ability to hydrate unsaturated LCFAs to saturated FAs. There was high correlation between cumulative in vitro gas production and fungal growth (94.78%), FP cellulose degradation (96.34%), CMCase activity(90.86%) or xylanase activity (87.67%). Thus measuring of cumulative gas production could be a useful tool for evaluating fungal growth and/or enzyme production by ruminal fungi.

• Journal of Applied Biological Chemistry
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• 제44권4호
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• pp.159-162
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• 2001

Plant stress incurred by flooding was studied in terms of oxidative stress, using greened rice seedlings subjected to a complete submergence followed by re-exposure to air under illumination ($30W/m^2$). It appeared that shoot tissues of the seedlings suffered oxygen deficiency during the flooding treatment, pertinent to the general concept. Interestingly enough, however, membrane peroxidation in shoots was enhanced by the submergence, as assessed by the content of 2-thiobarbituric acid-reactive substances (TBARS), and the re-aeration resulted in a rapid reduction of TBARS content. Such pattern of response was also seen in the change in the steady state level of $H_2O_2$. In contrast, superoxide dismutase and glutathione reductase that are involved in the detoxifying processes of superoxide in plant cells were significantly activated only during the re-aeration. These results allowed us to suggest the followings as a working hypothesis. Photorespiration-linked production of $H_2O_2$ may largely contribute to the increase in $H_2O_2$ level as well as TBARS production in shoots during the submergence. An abrupt re-supply of $CO_2$ by the re-aeration brings the photosynthetic apparatus back to full operation, suppressing photorespiration and probably causing a momentary, excess formation of superoxide and its dismutation product through side reaction, which gives rise to activating substrate-inducible antioxidative enzymes.

• 대한핵의학회:학술대회논문집
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• 대한핵의학회 1999년도 제38차 춘계학술대회
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• pp.189-192
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• 1999

$^{188}Re$ (${\beta}^-=2.2$ MeV; ${\gamma}^-$=155 keV; $T_{1/2}$=16.9 hours) is an attractive therapeutic radioisotope which is produced from decay of reactor-produced tungsten-188 parent ($T_{1/2}$=69 days). $^{188}W$ has been produced from the double neutron capture reaction of $^{186}W.\;^{188}Re$ can be easily obtained by elution of saline on alumina based $^{188}W/^{188}Re$ generator, which is commercially available. Complexes labelled with $^{188}Re$ have been developed for the radiotherapy treatment of diseases because of the desirable nuclear properties of the radioisotope and it's chemical properties similar to those of technetium, a well established diagnostic agent.