• Proceedings of the Korean Institute of Communication Sciences Conference
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• 2006.07a
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• pp.204-204
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• 2006

• Journal of Life Science
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• v.28 no.8
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• pp.992-998
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• 2018

Cancer cells grow in an environment composed of various components that supports tumor growth. Major cell types in the tumor microenvironment are fibroblast, endothelial cells and immune cells. All of these cells communicate with cancer cells. Among infiltrating immune cells as an abundant component of solid tumors, macrophages are a major component of the tumor microenvironment and orchestrates various aspects of immunity. The complex balance between pro-tumoral and anti-tumoral effects of immune cell infiltration can create a chronic inflammatory microenvironment essential for tumor growth and progression. Macrophages express different functional programs in response to microenvironmental signals, defined as M1 and M2 polarization. Tumor-associated macrophages (TAM) secret many cytokines, chemokines and proteases, which also promote tumor angiogenesis, growth, metastasis and immunosuppression. TAM have multifaceted roles in the development of many tumor types. TAM also interact with cancer stem cells. This interaction leads to tumorigenesis, metastasis, and drug resistance. TAM obtain various immunosuppressive functions to maintain the tumor microenvironment. TAM are characterized by their heterogeneity and plasticity, as they can be functionally reprogrammed to polarized phenotypes by exposure to cancer-related factors, stromal factors, infections, or even drug interventions. Because TAMs produce tumor-specific chemokines by the stimulation of stromal factors, chemokines might serve as biomarkers that reflect disease activity. The evidence has shown that cancer tissues with high infiltration of TAM are associated with poor patient prognosis and resistance to therapies. Targeting of TAM in tumors is considered a promising therapeutic strategy for anti-cancer treatment.

• Asia pacific journal of information systems
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• v.19 no.2
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• pp.73-94
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• 2009

The general aspects for the future warfare shows that the concept of firepower and maneuver centric warfare has been replacing with that of information and knowledge centric warfare. Thus, some developed countries are now trying to establish the information systems to perform intelligent warfare and innovate defense operations. The C4I(Command, Control, Communication, Computers and Intelligence for the Warrior) systems make it possible to do modern and systematic war operations. The basic idea of this study is to investigate how TAM(Technology Acceptance Model) can explain the acceptance behavior in military organizations. Because TAM is inadequate in explaining the acceptance processes forcomplex technologies and strict organizations, a revised research model based upon TAM was developed in order to assess the usage of the C4I system. The purpose of this study is to investigate factors affecting the usage of C4I in the Korean Army. The research model, based upon TAM, was extended through a belief construct such as self-efficacy as one of mediating variables. The self-efficacy has been used as a mediating variable for technology acceptance, and the variable was included in the research model. The external variables were selected on the basis of previous research. The external variables can be classified into following: 1) technological, 2) organizational, and 3) environmental factors on the basis of TOE(Technology-Organization-Environment) framework. The technological factor includes the information quality and the task-technology fitness. The organizational factor includes the influence of senior colleagues. The environmental factor includes the education/train data. The external variables are considered very important for explaining the behavior patterns of information technology or systems. A structured questionnaire was developed and administrated to those who were using the C4I system. Total 329 data were used for statistical data analyses. A confirmatory factor analysis and structured equation model were used as main statistical methods. Model fitness Indexes for measurement and structured models were verified before all 18 hypotheses were tested. This study shows that the perceived usefulness and the self-efficacy played their roles more than the perceived ease of use did in TAM. In military organizations, the perceived usefulness showed its mediating effects between external variables and dependent variable, but the perceived ease of use did not. These results imply that the perceived usefulness can explain the acceptance processes better than the perceived ease of use in the army. The self-efficacy was also used as one of the three mediating variables, and showed its mediating effects in explaining the acceptance processes. Such results also show that the self-efficacy can be selected as one possible belief construct in TAM. The perceived usefulness was influenced by such factors as senior colleagues, the information quality, and the task-technology fitness. The self-efficacy was affected by education/train and task-technology fitness. The actual usage of C4I was influenced not by the perceived ease of use but by the perceived usefulness and selfefficacy. This study suggests the followings: (1) An extended TAM can be applied to such strict organizations as the army; (2) Three mediation variables are included in the research model and tested at real situations; and (3) Several other implications are discussed.

• Korean Journal of Food Science and Technology
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• v.47 no.2
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• pp.191-197
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• 2015

We investigated the physicochemical properties and volatile flavor compounds in Taiwan Apple Mango (TAM) and Philippines Carabao Mango (PCM). The volatile flavor compounds were extracted using solid-phase microextraction (SPME) and analyzed by GC/MS. TAM and PCM have significantly different chemical composition, except for their crude ash. The moisture and crude fat contents were higher in TAM, whereas the crude protein and carbohydrate contents were higher in PCM. The major free sugars in order of concentration were sucrose, fructose, and glucose. We identified 56 and 59 volatile flavor compounds in TAM and PCM, respectively. Terpenes and their derivatives comprised 94.42% of the volatile flavor compounds in TAM, but only 63.79% of those in PCM. The acidic compound contents were higher in PCM than in TAM. ${\delta}$-3-Carene was the dominant flavor compound in these two mango cultivars. ${\alpha}$-Copaene, ${\alpha}$-guaiene, germacrene D, ${\alpha}$-bulnesene, and ${\gamma}$-gurjunene were found only in TAM, whereas ${\beta}$-myrcene, ${\alpha}$-phellandrene, ${\beta}$-phellandrene, ${\alpha}$-terpinolene, and cis-3-hexenyl butyrate were identified in PCM. Based on the results, we suggest that these compounds might contribute to the distinguishing flavor properties in different varieties of mango.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.10 no.8
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• pp.3972-3985
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• 2016

Organizations have been implementing mobile applications that actually connect to their backend enterprise applications (e.g. ERP, SCM, etc.) in order to increase the enterprise mobility. However, most of the organizations are still struggling to fully satisfy their mobile application users with the enterprise mobility. Even though it has been regarded as the right direction that the traditional enterprise system should move on, the studies on the success model for mobile enterprise applications in user's acceptance perspective can hardly be found. Thus, this study focused not only to redefine the success of the mobile enterprise application in user's acceptance persepective, but also to find the impacts of the factors on user's usage behavior of the mobile enterprise applications. In order to achieve this, we adopted the Technology Acceptance Model 2 (TAM2) as a model to figure out the user's behavior on mobile applications. Among various mobile enterprise applications, this study chose mobile ERP since it is the most representing enterprise applications that many organizations have implemented in their backend. This study found that not all the constructs defined by Davis in TAM2 have a significant influence on user's behavior of the mobile-ERP applications. However, it is also found that most social influence processes of TAM2 influence user's perception of the degree of interaction by mobile-ERP applications.

• Korean Management Science Review
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• v.21 no.1
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• pp.1-17
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• 2004

A separate and distinct interaction with both the actual e-vendor and with its IT web site interface is at the heart of online shopping. Previous research has established, accordingly, that online purchase intention is the product of customer assessments of IT itself, specifically its perceived usefulness and ease-of-use(TAM). Since perceived usefulness and perceived ease of use are such a fundamental driver of usage intentions, it is important to understand the determinants of this construct and how their influence changes over the voluntariness towards the usage intention. The reason for voluntariness as a moderating variable is that it had the serious effect to the motivating in the making willingness of the internet shopping-mall usage. A better understanding of the determinants of perceived usefulness and perceived ease of use to the usage intention would enable us to design web site interventions that would increase user acceptance and usage of internet shopping-mall. Therefore, the goal of the present research is to extend TAM to include additional key determinants of TAM and to understand how the effects of these determinants change with the voluntariness of the usage intention of the internet shopping-mall.

• Korean Management Science Review
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• v.19 no.2
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• pp.25-39
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• 2002

This study suggests a revised TAM (Technology Acceptance Model)-based performance evaluation model in MS (management science) education. Recently, many MS education programs are developed on the basis of computer and Internet communication technology. Previous researchers used TAM as an individual performance evaluation model, and proved that perceived usefulness and perceived ease of use are the substantive successful factors. This study provides a revised TAM-based conceptual framework for understanding what is involved in improving university MS education and what might be implied by conducting research on its improvement. It is argued in this research that three sets of forces and conditions have a direct and indirect impact on MS education ; first, each student has self efficacy and it is a critical determinant of behavior next, the use of Internet-based information system at MS education affects on the renewal of MS education : and finally, perceived usefulness and perceived ease of use have impacts on behavioral intention and actual system usage. This research concludes with suggestions for which direction this framework provides for future research on the premise and limits of efforts to renew MS education in university.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.10 no.6
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• pp.1191-1195
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• 2009

We present the efficient test wrapper design methodology considering the layout distance of scan chain. To test the scan chains in SoC, the scan chains must be assigned to external TAM(Test Access Mechanism) lines. The scan chains in IP were placed and routed without any timing violation at normal mode. However, in test mode, the scan chains have the additional layout distance after TAM line assignment, which can cause the timing violation of flip-flops in scan chains. This paper proposes a new test wrapper design considering layout distance of scan chains with timing violation free.

• Fashion & Textile Research Journal
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• v.18 no.1
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• pp.38-47
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• 2016

This research analyzes the influence of mobile commerce characteristics on consumer's purchase intention using a theoretical Technology Acceptance Model (TAM) constructed on previous studies and a review of the literature to explain the effect of mobile fashion shopping characteristics on consumer's purchase intention. In constructing structural equation model, Mobile commerce characteristics variables such as 'security', 'enjoyment', and 'personalization' were selected as external variables affecting TAM. A questionnaire was distributed to consumers in their 20's-30's who had purchased fashion products using a mobile shopping channel. Statistical methods of confirmatory factor analysis, correlation, and covariance structural analysis using Amos 19.0 package were employed for the analysis of 453 effective data responses. The results were as follows. First, extended TAM was shown be the appropriate model to explain the influence of mobile commerce characteristics on consumer's purchase intention in mobile fashion shopping. Second, 'security' had a significant positive influence on perceived usefulness (PU), however it affected perceived ease of use (PEOU) negatively. Third, 'enjoyment' had a significant influence only on PEOU, while 'personalization' was found to affect both PEOU and PU significantly. Fourth, PEOU affected PU significantly. Finally, both PEOU and PU had a significant influence on consumer's purchase intention.

• Journal of the Korean Society of Costume
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• v.58 no.6
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• pp.145-157
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• 2008

Vivienne Tam was born in mainland China and educated in Hong Kong and has worked mainly in New York. Within multi-cultural background, she has shown unique fashion designs where western styles and China esprit were harmonized.. This study analyzed the ethnic look featured on Vivienne Tam's design to identify how she has expressed her ethnic identity into fashion. Photos featuring ethnic appeal among her New York collection from 1996 S/S to 2005 F/W were analyzed in terms of shape/silhouette, color, fabric, motifs, detail and accessaries. She utilized frequently chinese motifs and patterns such as bamboo, panda, budha, flowers, letters, and masks. Secondly she modified the shapes of Chinese traditional costume like Quipao to render ethnic appeal. Color, fabric and detail like frog and embroidery also contributed to enhance China mood. Comparatively, she used western clothing items including shirts, blouses, skirts, pants, dresses, and coats and maintained the silhouette tight and fit so that most her designs look wearable and westernized.