• Genomics & Informatics
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• v.21 no.4
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• pp.49.1-49.11
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• 2023

Recent advances in sequencing technologies and platforms have enabled to generate metagenomics sequences using different sequencing platforms. In this study, we analyzed and compared shotgun metagenomic sequences generated by HiSeq3000 and BGISEQ-500 platforms from 12 sediment samples collected across the Norwegian coast. Metagenomics DNA sequences were normalized to an equal number of bases for both platforms and further evaluated by using different taxonomic classifiers, reference databases, and assemblers. Normalized BGISEQ-500 sequences retained more reads and base counts after preprocessing, while a slightly higher fraction of HiSeq3000 sequences were taxonomically classified. Kaiju classified a higher percentage of reads relative to Kraken2 for both platforms, and comparison of reference database for taxonomic classification showed that MAR database outperformed RefSeq. Assembly using MEGAHIT produced longer assemblies and higher total contigs count in majority of HiSeq3000 samples than using metaSPAdes, but the assembly statistics notably improved with unprocessed or normalized reads. Our results indicate that both platforms perform comparably in terms of the percentage of taxonomically classified reads and assembled contig statistics for metagenomics samples. This study provides valuable insights for researchers in selecting an appropriate sequencing platform and bioinformatics pipeline for their metagenomics studies.

• Korean Medical Education Review
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• v.26 no.2
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• pp.140-154
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• 2024

A physician's empathy plays a crucial role in patient-centered care, and in modern medicine, patients, their caregivers, and society demand a high level of empathy from healthcare providers. The conceptualization of clinical empathy, which has emphasized cognitive empathy since the mid-20th century, has been widely accepted in medical schools and the healthcare industry without much critical ref lection. This study provides an overview of the ongoing debates on empathy versus sympathy and cognitive empathy versus affective empathy to clarify the concept of empathy. Based on recent research findings, clinical empathy is proposed to encompass three components: cognitive empathy, affective empathy, and empathic motivation. It is suggested that fully demonstrating these components requires empathic communication skills. Additionally, the cognitive characteristics of medical students and the features of the academic environment demonstrate the need for education to strengthen their empathy skills. Considering this, proposed intervention methods that medical schools can consider include utilizing tutoring programs and debriefing processes for team activities, which can facilitate problem-solving as a coping strategy for stress. Learning communities can create an environment where students can receive social support and recover from stress. Medical schools can contribute to the development of students' professional identities as practicing clinicians who embody empathy and respect by cultivating professors as positive role models. Additionally, utilizing scales to assess the empathic nature of doctor-patient communication or incorporating patients and caregivers as evaluators can actively improve empathic communication skills.

• Steel and Composite Structures
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• v.51 no.4
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• pp.457-471
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• 2024

In this research, for the first time the instability boundaries for a spinning shaft reinforced with graphene nanoplatelets undergone the principle parametric resonance are determined and examined taking into account the gyroscopic effect. In this respect, the extracted equations of motion in our previous research (Ref. Asadi et al. (2023)) are implemented and efficiently upgraded. In the upgraded discretized equations the effect of the Rayleigh's damping and the varying spinning speed is included that leads to a different dynamical discretized governing equations. The previous research was about the free vibration analysis of spinning graphene-based shafts examined by an eigen-value problem analysis; while, in the current research an advanced mechanical analysis is addressed in details for the first time that is the dynamics instability of the aforementioned shaft subjected to the principal parametric resonance. The spinning speed of the shaft is considered to be varied harmonically as a function of time. Rayleigh's damping effect is applied to the governing equations in order to regard the energy loss of the system. Resorting to Bolotin's route, Floquet theory and β-Newmark method, the instability region and its accompanied boundaries are defined. Accordingly, the effects of the graphene nanoplatelet on the instability region are elucidated.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.43 no.2 s.344
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• pp.18-23
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• 2006

In this paper, we derive a novel eigenvalue equation of double silica layers on silicon only for TE mode and present the method as an example how to use it to determine the refractive indices and thicknesses with prism coupler. Our method to solve eigenvalue equation have good merit rather than [5] in that the equation is real and iteration parameters can be reduced from four to three. The average magnitude of the errors is less than $10^{-5}\~10^{-6}$ approximately

• Journal of Ecology and Environment
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• v.34 no.2
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• pp.193-202
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• 2011

We studied temperature sensitivity characteristics of soil respiration during periods of rising and falling temperatures within a common temperature range. We measured soil respiration continuously through two periods (a period of falling temperature, from August 7, 2003 to October 13, 2003; and a period of rising temperature from May 2, 2004 to July 2, 2004) using an open-top chamber technique. A clear exponential relationship was observed between soil temperature and soil respiration rate during both periods. However, the effects of soil water content were not significant, because the humid monsoon climate prevented soil drought, which would otherwise have limited soil respiration. We analyzed temperature sensitivity using the $Q_{10}$ value and $R_{ref}$ (reference respiration at the average temperature for the observation period) and found that these values tended to be higher during the period of rising temperature than during the period of falling temperature. In the absence of an effect on soil water content, several other factors could explain this phenomenon. Here, we discuss the factors that control temperature sensitivity of soil respiration during periods of rising and falling temperature, such as root respiration, root growth, root exudates, and litter supply. We also discuss how the contribution of these factors may vary due to different growth states or due to the effects of the previous season, despite a similar temperature range.

• Transactions of the Korean Society of Mechanical Engineers
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• v.17 no.10
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• pp.2398-2406
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• 1993

Abdi's numerical method(ref.13) for representing a stress singularity by shifting the mid-side nodes of isoparametric elements is reviewed. A simple technique to obtain the optimal position of the mid-side nodes in quadratic isoparametric finite element is presented. From this technique we can directly obtain the position of the side-nodes adjacent to the crack tip. It is also observed that the present technique provides good accuracy for the expression of the opening displacement and the determination of the mid-side nodes for more wide range of material properties than that obtained by Abdicant the finite element method is applied to determine stress intensity factors for pressurized crack perpendicular to and terminating at the interface of two bonded dissimilar materials. A proper definition for stress intensity factors of a crack perpendicular to bimaterial interface is provided. It is based upon a near-tip displacement solutions on the crack surface for interface crack between two dissimilar materials. Numerical testing is carried out with the eight-node and six-node elements. The results obtained are compared with the previous solutions.

• Journal of the Society of Naval Architects of Korea
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• v.33 no.2
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• pp.56-64
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• 1996

In this study, a review is made of the previous work(Ref. 1 and 5) for the development of the limit design method of the flat rectangular grillages under the lateral pressure. And the effect of the in-plane loads on the collapse theory is considered. The main part of the work is devoted in developing the standard design method of grillages under the criteria of minimum weight and minimum cost. In the final part, it was shown that Pareto solution methods can be easily applied to structural optimization with the multiple objectives, and the designer can have an appropriate choice from those Pareto optimal solutions.

• Journal of IKEEE
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• v.2 no.2 s.3
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• pp.178-184
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• 1998

Optical fiber coupler is a crucial optical passive component for optical transmission systems. In this paper, we fabricate wavelength insensitive optical coupler(WIC), of two types for which the processing procedures are complicate and difficult. These couplers are fabricated by two optical fibers having either different fiber parameters or different cladding diameters. To clarify the validity, we measure the optical characteritics and compare to the data of theoretical simulation. The experiment results ref#eat that it has uniformity of about 1.0 dB and excess loss of less than 0.1 dB in the range of $1310{\pm}40nm\;and\;1550{\pm}40nm$.

• Proceedings of the Acoustical Society of Korea Conference
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• spring
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• pp.224-227
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• 1999

A high power deep-water sonar transducer of FFR (Free Flooded Ring) type has been designed using a coupled FE-BEM. The present sonar transducer is composed of rectangular piezoelectric ceramics and pie-shaped steels (or the advantage of simple fabrication. The dynamics of the sonar transducer is modelled in three dimensions and is analyzed with external electrical excitation conditions. Different results are available such as steady-state frequency response for TX and RX displacement modes, directivity patterns, back-scattering patterns, bandwidths, transmitting voltage responses and receiving sensitivity responses. The TV response shows a very high acoustic pressure of 150 dB/lV (ref $1{\mu}Pa$ at 1m) at 1900 Hz. This ultra high power response of the sonar transducer indicates a new possibility of the sonar transducer development.

• Proceedings of the International Microelectronics And Packaging Society Conference
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• 2003.11a
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• pp.151-155
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• 2003

The requirements for harsh environment electronic controllers in automotive applications have been steadily becoming more and more stringent. Electronic substrate technologists have been responding to this challenge effectively in an effort to meet the performance, reliability and cost requirements. An effect of the plasma cleaning at the alumina substrate and the IMC layer between $Sn-37wt\%Pb$ solder and Ag-Pd thick film conductor after reflow soldering has been studied. Organic residual carbon layer was removed by the substrate plasma cleaning. So the interfacial adhesive strength was enhanced. As a result of AFM measurement, Ag-Pd conductor pad roughness were increased from 304nm to 330nm. $Cu_6Sn_5$ formed during initial ref]ow process at the interface between TiWN/Cu UBM and solder grew by the succeeding reflow process so the grains had a large diameter and dense interval. A cellular-shaped $Ag_3Sn$ was observed at the interface between Ag-Pd conductor pad and solder. The diameters of the $Ag_3Sn$ grains ranged from about $0.1\~0.6{\mu}m$. And a needle-shaped $Ag_3Sn$ was also observed at the inside of the solder.