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Effects of ${\beta}-glucan$ from Lentinus edodes and Hordeum vulgare on Blood Glucose and Lipid Composition in Alloxan-induced Diabetic Mice (표고버섯과 보리에서 추출한 ${\beta}-glucan$이 Alloxan 유발 당뇨 마우스의 혈당 및 지질 성분에 미치는 영향)

  • Song, Ji-Young;Yoon, Ki-Ju;Yoon, Hae-Kyung;Koo, Sung-Ja
    • Korean Journal of Food Science and Technology
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    • v.33 no.6
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    • pp.802-807
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    • 2001
  • Effects of ${\beta}-glucan$ from Lentinus edodes and hordeum vulgare on blood glucose and lipid composition were investigated. Diabetes mellitus was induced in male ICR mice by the injection of alloxan into the tail vein at a dose of 75 mg/kg. The ${\beta}-glucan$ were administered orally for 10 days and the normal and alloxan-control group were orally administered with saline. The body weight gain and food intake were monitored every day and plasma levels of glucose, triglyceride, total cholesterol, LDL-cholesterol were determined at last day. Also the weight of liver, heart, spleen and kidney were determined. The ${\beta}-glucan$ from Lentinus edodes and hordeum vulgure lowered significantly body weight gain in alloxan-induced diatetic mice (p<0.05) and plasma glucose levels compared to that of alloxan-control group. Plasma triglyceride level in B500 was lowered in alloxan-induced diabetic mice. The ${\beta}-glucan$ of hordeum vulgare lowered weight of liver significantly (p<0.05). In conclusion, it was assumed that ${\beta}-glucan$ from hordeum vulgare have anti-hyperglycemic and anti-obese effects by reducing body weight gain and decreasing serum glucose and triglyceride level.

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Effects of Irrigation and Sowing Time on Growth and Yield of Bupleurum falcatum L. (시호(柴胡) 생육(生育)과 수량(收量)에 대한 파종기(播種期) 및 초기관수(初期灌水) 효과(效果))

  • Kim, Jae-Chul;Kim, Jung-Hye;Ryu, Joung-Ki;Kim, Ki-Jae;Park, Jun-Hong
    • Korean Journal of Medicinal Crop Science
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    • v.5 no.4
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    • pp.318-324
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    • 1997
  • When Bupleurum falcatum field was irrigated three times with 20mm at intervals of 10days after sowing, establishment was inproved (64%) and root yield increased to 58kg/10a. And in early growing stage, 30mm irrigation six times at intervals of 10days increased the number of harvested plants per square meter and resulted in yield increase by 26% over yield from natural plot. 20mm irrigation in sowing time at intervals of 10days and 30mm irrigation in early growing stage at intervals of 10days kept adequate soil moisture content (soil moisture tension: $0.39{\sim}0.49bar)$ and resulted in better establishment, growth and yield of Buleurum falcatum.

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Studies on the Seed Development and Germination of Adenophora triphylla DC (잔대 종자(種子) 발육(發育) 및 발아(發芽) 특성(特性))

  • Kim, Sun;Park, Moon-Soo;Park, Ho-Ki;Jang, Young-Sun
    • Korean Journal of Medicinal Crop Science
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    • v.3 no.1
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    • pp.66-70
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    • 1995
  • These experiments were conducted to investigate the growth and characteristics of Adenophora triphylla DC. seed, and effects of some pretreatments and light condition on the gemination of it. The results were as follows. Seed coat was soft and white at 30 days after flowering, but it became hard and brown from 40 days. The 1,000 grain weight was 247mg at 40 days after flowering and high at 50 days as 268mg, and decreased from 60 days. Germination percentage was highest at 100ppm $GA_3$ treatment for 24 hours as 96.7% and 88.3% at moistured treatment at $0^{\circ}C$ for 7 days, but only 40% at control. Adenophora triphylla. seed was light germinator, but it could be germinated 80% even under dark condition if $GA_3$ was treated 100ppm for 24 hours. The optimum temperature of germination in Adenophora triphylla. seeds was $25^{\circ}C$.

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Preference and Evaluation of Image for Modern Application of Korean Traditional Patterns (현대적 응용을 위한 한국 전통무적의 선호도 및 이미지 평가)

  • Cho, Ji-Hyun;Kim, Young-Eun
    • Korean Journal of Human Ecology
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    • v.10 no.4
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    • pp.399-409
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    • 2001
  • The purpose of this study was to evaluate the preference of image for modern application of Korean traditional patterns. A survey was conducted using the random selection among female undergraduate students in Daegu city. The degree of interest and preference in Korean traditional style or something like that measured by 5 scale method. And then they were classified into two groups which were interest/non-interest group, and preference/non-preference group. The image of Korean traditional patterns consisted of semantic differential scales. Frequency, percentage and mean were analyzed, for difference of groups t-test was analyzed. The results were as fellows; 1. For the degree of interest for Korean traditional patterns, it was showed that 53.8% of total respondents took interest and about 40.4% of them had preference for traditional patterns. the correlation coefficient of the degree of interest and preference was 0.782(p<0.01) and showed that the positive correlation was high. 2. Among 20 kinds of Korean traditional patterns, the degree of preference for the patterns of plants and nature was quite high whereas that for the patterns of geometrical things was low relatively. 3. It was evaluated that pattern of nature was fresh, refined and womanly image generally. It was evaluated that pattern of plants was womanly, fresh, weak, light and soft image and that of animals was heavy, splendid, high-class, manly, strong and positive image. It was evaluated that pattern of geometrical things was the most refined image and high-class, rigid and strong. 4. The statistical significance of mean between interest/non-interest group was showed statistically in the patterns of clouds, mountains, lotus, apricot, orchid, dragon, phoenix and bogey. In case of pattern of orchids, the degree of preference was most different between interest/non-interest group. 5. The pattern of plants showed the most different evaluation for images between interest/non-interest group. For refined/old-fashioned polar adjective images, the interest group evaluated the pattern of plants more refined. 6. For pattern of orchids, the difference of degree of preference between preference/non-preference group was most remarkable in Korean traditional patterns. 7. The pattern of geometrical things showed the most different evaluation for images between preference/non-preference group. For warm/cool polar adjective images, the preference group evaluated the pattern of geometrical things cooler.

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A Study on a Menu Planning Program in Institutional Food Service by Personal Computer (개인용 컴퓨터를 이용한 단체급식 식단 작성 프로그램에 관한 연구)

  • Kang, Hyeon-Ju;Kim, Il
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.21 no.6
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    • pp.662-671
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    • 1992
  • The purpose of this study was to develop a software system for menu planning program in an institutional food service. In this research, a Qnix-7700/AT(16 bit personal computer) compatible with IBM-PC/AT was used and all the files and programs were created by using COBOL. This study provides food service managers with more effective management system by personal computerized menu planning program. Software programs developed in this study were summerized as follows : (1) Programs for outputing standard amounts of the basic food groups. (2) Programs for inputing the cooking type code, the food code and the food amount of the menu. (3) Programs for outputing distribution of the basic food groups of the computerized menu. (4) Programs for calculating the price of each food and menu. (5) Programs for calculating the nutrient content of each food and menu. (6) Programs for outputing the purchasing amount of food. (7) Programs for outputing the menu table. (8) Programs for inputing and modifing the food composition in the food composition file. (9) Programs for inputing and modifing the cooking types in the cooking types file. (10) Programs for inputing and modifing the food prices in the food prices file.

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A Study of Goiwhasan's Antigastric ulcer and Blood Hemostasis (괴화산(槐花散)이 항소화성궤양(抗消化性潰瘍) 및 혈액(血液) 응고작용(凝固作用)에 미치는 실험적(實驗的) 연구(硏究))

  • Kang, Jae-Chun;Park, Dong-Won;Ryu, Bong-Ha
    • The Journal of Korean Medicine
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    • v.19 no.1
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    • pp.179-204
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    • 1998
  • The purpose of this research was to investigate the efficacy of Goiwhasan extract powder on the gastric injuries, antiulcer, gastrointestinal tract and blood hemostasis. Animals were used through this studies mice and rats. All animals were divided into 3 groups, contol group(no treatment), sample Ⅰ group(375mg/kg administration), sample Ⅱ group(750mg/kg administration). The gastric injuries and ulcer have been made by using pyloric ligation, indomethacin, HCI-ethanol, acetic acid and then The histological observation was followed. In the gastrointestinal tract, gastric juice secretion, gastric acidity, pepsin output, blood gastrin and secretin level, transport potentials in the small and large intestine were checked. And studies on blood hemostasis were performed on normal hemostatic activities and plasma prothrombin time, plasma recalcification time, plasma fibrinogen levels in the hypoprothrombinemic mice induced by warfarin. The results were as follows: 1. The antigastric ulcer effects on the pyloric ligation, indomethacin, HCl-ethanol, acetic acid induced gastric injuries were shown in Sample Ⅱ group(p<0.05). 2. Through the morphologic examination on the acetic acid induced ulcer, Sample Ⅰ group showed mild regeneration of epithelium and slight decrease of periulcer edema then that of Control group, while Sample Ⅱ group showed more retraction of round ulcer site, remarkable loss of swelling and edema then that of Control group, and revealing the regenerated epithelium in the surrounding ulcer site. Thus it was noted that both Sample groups have antigastriculcer effects on the experimentally induced gastric ulcer. 3. The inhibitory effects on gastric juice were noted in both Sample Ⅰ group(p<0.05) and Sample Ⅱ group(p<0.01). However, only Sample Ⅱ group showed the inhibitory effects on total acidity and pepsin output(p<0.05). 4. The significant inhibition of blood gastrin level showed at 30 min.(P<0.05) and 90 min.(P<0.05) after starting medication in only Sample Ⅱ group, but significance of blood secretin level in both groups was not recognized. 5. Any significant changes in barium sulfate transport in the small intestine of mice was not recognized in both groups, but the significantly inhibitory effect in large intestine was recognized in both Sample Ⅰ group(p<0.05) and Sample Ⅱ group(p<0.001). 6. In hemostatic effect on both normal mice and hypoprothrombinemic mice induced by warfarin, the significantly shortening effect on coagulation time was seen in only Sample Ⅱ group(p<0.01). 7. On plasma prothrombin time in hypoprothrombinemic rat induced by warfarin, Sample Ⅱ group have shortened the prothrombin time significantly(p<0.001). 8. On plasma reclcification time in hypoprothrombinemic rat induced by warfarin, the recalcification time have been shortened significantly in both Sample Ⅰ group(p<0.05) and Sample Ⅱ group(p<0.01). 9. On plasma fibrinogen levels in hypoprothrombinemic rat induced by warfarin, the fibrinogen contents in Sample Ⅱ have been decreased significantly(p<0.01). Overall the above results suggest that Goiwhasan has an therapeutic efficacy on antigastric ulcer and blood hemostasis. Further studies would be needed on the interaction of its herbal medicine and its mechanism in the future.

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An Evaluation of the Virtual Refraction Education (가상 굴절검사 교육에 대한 평가)

  • Yu, Dong-Sik;Son, Jeong-Sik;Chu, Byoung-Sun
    • Journal of Korean Ophthalmic Optics Society
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    • v.13 no.2
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    • pp.43-50
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    • 2008
  • Purpose: The purpose of this study is to evaluate the effect of a VR (Virtual Refractor), which is a simulator for a PR (Practical Refraction), as an educational tool. Methods: Twenty four third year students enrolled in the department of visual optics volunteered for VR education. Each student attended a VR training course and practiced with the VR by themselves. One month later, each student tested three virtual subjects on the VR and one real subject on the PR and were given a performance score for each refraction. And the scores for the virtual and practical refractions were compared. In addition, a self-report questionnaire based on a five point Likert-scale was designed, consisting of domains such as spontaneous participation, contribution for the refraction, confirmity of the VR and PR, and necessity of the VR. Results: The Spearman's correlation coefficient between the testing score of the practical and virtual refractions indicated a significantly correlation (R=0.71, p<0.001). In the questionnaire, the mean score of the domains was 3.67${\pm}$0.96 and it indicated that students expressed that using the VR was beneficial. The correlation value among these domains was a high significant level, 0.91~0.68 (p<0.001). Conclusions: Although the VR required certain improvements in its concentration and systematic approaches for practical situations, it showed a high correlation between the VR and the PR and represented a positive evaluation in the PR.

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Thrombotic thrombocytopenic purpura with decreased level of ADAMTS-13 activity and increased level of ADAMTS-13 inhibitor in an adolescent (청소년기에 발생한 ADAMTS-13 활성도 저하와 항체 양성을 보인 혈전저혈소판혈증자색반병 1례)

  • Yang, Eun Mi;Han, Dong Kyun;Baek, Hee Jo;Shin, Myung Geun;Kim, Young Ok;Kook, Hoon;Hwang, Tae Ju
    • Clinical and Experimental Pediatrics
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    • v.53 no.3
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    • pp.428-431
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    • 2010
  • Thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathy characterized by endothelial cell damage, resulting in microangiopathic hemolytic anemia, thrombocytopenia, and various degrees of neurological and renal impairment caused by microvascular thrombi. It is rare in children and frequently follows a fatal course. TTP is divided into 2 types: one is inherited and associated with ADAMTS-13 gene mutations and the other is acquired and associated with anti-ADAMTS-13 autoantibodies. The measurement of ADAMTS-13 activity in plasma, identification of ADAMTS-13 circulating inhibitor, anti-ADAMTS-13 IgG, and ADAMTS-13 gene sequencing are crucial to the diagnosis of TTP. Plasma exchanges are the first-line treatment for acquired TTP, combined with steroids and immunosuppressive drugs. Here, we describe the case of an adolescent patient with TTP, confirmed by decreased level of ADAMTS-13 activity and an increased level of ADAMTS-13 inhibitor, who was successfully treated by plasma exchanges.

Allocation Problem in Door to Door Delivery Service Network (택배 운송 네트워크 설계를 위한 할당 문제)

  • 정기호;고창성
    • Proceedings of the Korean Operations and Management Science Society Conference
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    • 2002.05a
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    • pp.987-993
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    • 2002
  • 최근 들어 전자상거래의 급속한 발달로 전 세계적으로 수송 물동량이 급격히 증대되고 있고, 이로 인해 택배사업이 대단히 활성화되고 있다. 출발지와 목적지가 서로 상이한 무수히 만은 수송 요구가 들어오면 수송 요구화물의 신속한 집배송을 위한 배차계획 및 수송계획을 세우는 것이 택배회사의 주요 업무이다. 이러한 배차 계획 및 수송 계획을 어떻게 수립하느냐에 따라 전체 수송비용뿐만 아니라 고객들의 서비스 수준에 상당한 영향을 미치게 된다. 그러나 이러한 운영적 차원에서의 의사결정 이전에 훨씬 중요하게 고려해야 할 내용이 택배네트워크의 설계 문제이다. 이러한 택배네트워크의 설계에는 터미널 개수 및 위치를 결정하는 전략적 문제와 영업소들을 터미널에 할당하는 전술적 문제로 구분될 수 있다. 현재 우리 국내에는 크고 작은 수많은 택배사업자들이 있으나, 그 중에서 비교적 규모가 큰 주요 택배회사들은 대부분 전국에 걸쳐 다수의 터미널을 설치하여 두고 수송화물의 집배송을 위한 물류거점으로 운영하고 있다. 이와 같은 터미널 위치 및 개수가 정해진 상태에서 전국에 걸쳐 분포되어 있는 영업소들을 어떤 터미널에 할당하여 처리되도록 하느냐의 여부는 수송비용 측면에서뿐만 아니라 고객들에 대한 서비스 측면에서 대단히 중요한 의사결정 중의 하나이다. 본 연구에서는 비용과 시간을 고려하여 전국에 걸쳐 분포되어 있는 영업소들을 어떤 터미널에 할당해야 하는지를 결정하기 위한 수리적 모형을 제시하고, 이에 대한 탐색적 해법을 제시하며, 국내의 택배회사 사례를 대상으로 모형을 적용해 보고자 한다.무가 많이 발생하는 유통 분야의 프랜차이즈 산업을 대상으로 기업정보시스템 구현 및 경쟁력 강화를 뒷받침하기 위해서, 기업간 프로세스 협업(collaboration) 부분의 데이터 및 서식, 이를 취급하는 기능과 프로세스에 대란 분석을 통해 업무 프로세스 모델링 방법론과 관련한 모델링 지침 및 메타모델을 이용한 표준 업무 프로세스 모델을 개발하여 기업간 업무 프로세스 표준화에 대한 체계적인 관리에 대한 방안을 연구하고자 한다.의Bullwhip effect를 감소시킬 수 있는 장점이 있다. 동시에 이것은 향후 e-Business 시스템 구축을 위한 기본 인프라 역할을 수행할 수 있게 된다. 많았고 년도에 따른 변화는 보이지 않았다. 스키손상의 발생빈도는 초기에 비하여 점차 감소하는 경향을 보였으며, 손상의 특성도 부위별, 연령별로 다양한 변화를 나타내었다.해가능성을 가진 균이 상당수 검출되므로 원료의 수송, 김치의 제조 및 유통과정에서 병원균에 대한 오염방지에 유의하여야 할 것이다. 확인할 수 있었다. 이상의 결과에 의하면 고농도의 유기물이 함유된 음식물쓰레기는 Hybrid Anaerobic Reactor (HAR)를 이용하여 HRT 30일 정도에서 충분히 직접 혐기성처리가 가능하며, 이때 발생된 $CH_{4}$를 회수하여 이용하면 대체에너지원으로 활용 가치가 높은 것으로 판단된다./207), $99.2\%$(238/240), $98.5\%$(133/135) 및 $100\%$ (313)였다. 각

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Sustained release granular formulation with oil-soluble binder (유용성 점결제를 이용한 수중용출지연입제의 제제)

  • Yu, Ju-Hyun;Lee, Byung-Hoi;Cho, Kwang-Yun
    • Applied Biological Chemistry
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    • v.35 no.2
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    • pp.76-81
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    • 1992
  • The technicals of KC-7079, isoprothiolane, perfluidone and tricyclazole were granulated with a mixture of inorganic carrier and oil-soluble binder, that is, stearly alcohol or ethyl cellulose. The concentration of the released active ingredient from the granules was analyzed at several days intervals after immersion of these granules in water at $25^{\circ}C$. At the content of stearyl alcohol less than $80g\;kg^{-1}$, the granule kneaded with stearyl alcohol mixture and water disintegrated in water. But the granule kneaded with methanol disintegrated in water at the content of stearyl alcohol less than $30g\;kg^{-1}$. The less the KC-7079-stearyl alcohol granule disintegrated, the slower the release rate of KC-7079 was. No matter how was increased the stearyl alcohol content, the release rate of KC-7079 granule which did not disintegrate was not significantly changed. The sustained releasing effect of the granules was little in the other three pesticides of which the water solubility was higher than of KC-7079(21 ppm). The granule made of ethyl cellulose did not disintegrate even at $5g\;kg^{-1}$ of ethyl cellulose. With the increase of ethyl cellulose content and the decrease of active ingredient in the granules, the sustaining effect of the granules on releasing acitive ingredient was increased. The lower the water solubility of pesticide was, the release rate tended to be sustained except perfluidone.

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