• 한국축산시설환경학회지
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• 제8권3호
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• pp.165-170
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• 2002

This study was carried out to measure the 3D-distance of a cow model teat for an application possibility on Robotic Milking System(RMS). A teat recognition algorithm was made to find 3D-distance of the model by using Gonzalrez's theory. Some of the results are as follows. 1 . In the distance measurement experiment on the test board, as the measured length, and the length between the center of image surface and the measured image point became longer, their error values increased. 2. The model teat was installed and measured the error value at the random position. The error value of X and Y coordinates was less than 5㎜, and that of Z coordinates was less than 20㎜. The error value increased as the distance of camera's increased. 3. The equation for distance information acquirement was satisfied with obtaining accurate distance that was necessary for a milking robot to trace teats, A teat recognition algorithm was recognized well four model cow teats. It's processing time was about 1 second. It appeared that a teat recognition algorithm could be used to determine the 3D-distance of the cow teat to develop a RMS.

• 한국토양비료학회지
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• 제42권Spc호
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• pp.45-46
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• 2009

간척지 토양은 도시화와 산업화로 인해 잠식되는 농경지를 대체하는 식량공급원으로 간척지는 쌀 산업 외에 원예, 축산 등 다양한 생물산업 기반으로 활용되고 있다. 그리고 간척지 논농업(간척지 논 307만 ha)은 온실가스 저감 기능을 가지고 있으며 년간 논 1ha당 이산화탄소 흡수량 21.9t, 산소 공급량 15.9t으로 알려져 있다. 그러나 높은 염농도와 지하수위, 지하수 상승에 의한 재염화 현상, 토양 물리화학성과 배수 불량, 논의 경우 적정 유효토심은 50cm 정도이나 간척지 논 유효토심 20cm 이하로 유효토심이 매우 낮은 편이다. 또한 간척년대 경과할수록 제염은 되나 토양물리성 불량, 시비량 과다와 양분 불균형 발생으로 인하여 수분과 양분보유능 향상 토양관리 기술 개발 필요하다.

• 대한방사선치료학회지
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• 제32권
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• pp.41-52
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• 2020

목 적: Hypopharynx Cancer의 VMAT 치료 시 Neck 부분에 Commercial Bolus(이하 CB)와 3D Printing 기술로 제작한 3D Bolus를 각각 적용한 두 치료 계획을 비교함으로써 3D Bolus 적용의 선량학적 유용성, setup 재현성 및 효율성을 알아보고 임상적 적용 가능성을 평가하고자 한다. 대상 및 방법: CB를 적용한 RANDO phantom의 CT image를 바탕으로 3D Bolus를 동일한 형태로 제작하였다. 3D Bolus는 OMG SLA 660 Printer, MaterialiseMagics software를 이용하여 SLA기법을 통해 밀도 1.2 g/㎤의 폴리우레탄 아크릴레이트 수지로 출력하였다. CB와 3D Bolus를 적용한 두 CT image를 바탕으로 Hypopharynx Cancer의 VMAT 치료를 가정하여 치료 계획을 수립하였다. 수립한 두 치료 계획을 각각 18회에 걸쳐 CBCT image를 획득하였고, 매 회 setup time을 측정하여 치료 효율성을 평가하였다. 획득한 CBCT image를 바탕으로 전산화 치료계획 시스템 Pinnacle을 통해 Adaptive Plan을 진행함으로써 Target, 정상 장기 선량 평가와 Bolus Volume의 변화를 평가하였다. 결 과: 각 치료 계획에 대한 setup time은 CB 적용 치료 계획에 비해 3D Bolus 적용 치료 계획에서 평균 28 sec 감소하였다. 치료 전 기간 내 Bolus Volume 변화는 CB Initial Plan 83.9㎤에서 86.1±2.70㎤, 3D Bolus Initial Plan 92.2㎤에서 99.8±0.46㎤로 나타났다. CTV Min Value의 변화는 CB Initial Plan 191.6cGy에서 167.4±19.38cGy, 3D Bolus Initial Plan 167.3cGy에서 149.5±18.27cGy로 나타났다. CTV Mean Value의 변화는 CB Initial Plan 227.1cGy에서 228.3±0.38cGy, 3D Bolus Initial Plan 225.9cGy에서 227.7±0.30cGy로 나타났다. PTV Min Value의 변화는 CB Initial Plan 128.5cGy에서 74.9±19.47cGy, 3D Bolus Initial Plan 139.9cGy에서 83.2±12.92cGy로 나타났다. PTV Mean Value의 변화는 CB Initial Plan 225.4cGy에서 226.2±0.83cGy, 3D Bolus Initial Plan 224.1cGy에서 225.8±0.33cGy로 나타났다. 정상 장기 Spinal Cord에 대한 Max Value는 매 회 평균 135.6cGy로 동일하게 나타났다. 결 론: 본 논문의 실험 결과를 통해 불균등한 체표면에 대한 3D Bolus의 적용이 Commercial Bolus 적용에 비해 선량학적으로 유용하고 setup 재현성 및 효율성 또한 우수함을 알 수 있었다. 추후 3D Printing 재료의 다양성에 대한 연구와 함께 추가적인 사례 연구가 진행된다면 방사선 치료 분야에서 3D Bolus의 적용이 더욱 활발하게 진행될 것으로 사료된다.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제19권3호
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• pp.186-192
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• 2016

Purpose: To evaluate the correlation between colon transit time (CTT) test value and initial maintenance dose of polyethylene glycol (PEG) 4000 or lactulose. Methods: Of 415 children with chronic functional constipation, 190 were enrolled based on exclusion criteria using the CTT test, defecation diary, and clinical chart. The CTT test was performed with prior disimpaction. The laxative dose for maintenance was determined on the basis of the defecation diary and clinical chart. The Shapiro-Wilk test and Pearson's and Spearman's correlations were used for statistical analysis. Results: The overall group median value and interquartile range of the CTT test was 43.8 (31.8) hours. The average PEG 4000 dose for maintenance in the overall group was $0.68{\pm}0.18g/kg/d$; according to age, the dose was $0.73{\pm}0.16g/kg/d$ (<8 years), $0.53{\pm}0.12g/kg/d$ (8 to <12 years), and $0.36{\pm}0.05g/kg/d$ (12 to 15 years). The dose of lactulose was $1.99{\pm}0.43mL/kg/d$ (<8 years) or $1.26{\pm}0.25mL/kg/d$ (8 to <12 years). There was no significant correlation between CTT test value and initial dose of laxative, irrespective of the subgroup (encopresis, abnormal CTT test subtype) for either laxative. Even in the largest group (overall, n=109, younger than 8 years and on PEG 4000), the correlation was weak (Pearson's correlation coefficient [R]=0.268, p=0.005). Within the abnormal transit group, subgroup (n=73, younger than 8 years and on PEG 4000) correlation was weak (R=0.267, p=0.022). Conclusion: CTT test value cannot predict the initial maintenance dose of PEG 4000 or lactulose with linear correlation.

• 한국산학기술학회논문지
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• 제9권3호
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• pp.822-830
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• 2008

본 논문은 기업의 연구개발 관련 지출이 기업가치에 긍정적 영향을 미치는가를 증권거래소(KSE)상장기업과 코스닥(KOSDAQ)기업을 대상으로 하여 실증적으로 확인하는 것을 목표로 한다. 실증적 분석 결과, 두 시장 모두에서 연구개발비 총액은 기업 가치에 대하여 유의하게 긍정적 영향을 미치고 있었으며, 자산으로 계상한 연구개발비를 포함시킨 모형, 비용으로 계상한 연구개발비를 포함하는 모형들도 모두 두 시장에서 기업 가치에 유의한 긍정적 효과를 나타낸다는 결과가 나타났다. 두 시장 모두에서 자산으로 계상된 연구개발 지출보다는 비용으로 계상된 연구개발비가 기업 가치에 유의한 긍정적 효과를 나타낸다는 결과가 도출되었다.

• Asian Journal of Innovation and Policy
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• 제6권2호
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• pp.192-205
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• 2017

The aim of this study is to investigate the relative impact of the image of information service on customer's perceived value and satisfaction of R&D information. It also seeks to assess the moderating effect of service users' skills on the value of the service image on the customer. For this purpose, a field study was conducted on users of a public R&D information service called NTIS (National Technology Information Service) in Korea. The findings show that the information service image has a significant impact on customers' perceived value and satisfaction. In addition, customers' perceived value is found to be an important indicator in strengthening customer satisfaction. Findings also reveal that individual personal computer skills moderate the relationship between service image and information value. Further research is needed to strengthen the independent variable in view of the increasing pressure to improve public service quality and customer management.

• Asian-Australasian Journal of Animal Sciences
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• 제19권7호
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• pp.927-930
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• 2006

This study was conducted to investigate potential effects of previously identified QTL regions on carcass traits in Hanwoo. The data analyzed in this study was collected from 326 steers of 67 proven sire. Thirteen micorsatellite markers spanning QTL regions on bovine chromosomes 1 and 14 were genotyped in 326 steers. The following breeding values were analyzed for QTL effects. Cold carcass weight breeding value (CCWBV), longissimus muscle area breeding value (LMABV), marbling score breeding value (MSBV) and backfat thickness breeding value (BFTBV). Chi-square tests were performed to compare frequencies of individual allele between high and low breeding value groups. Significant differences of allele frequencies in BMS711, MCM130, BMS4049, and BMS2263 were found. And also, in RM180, BL1029, BM4305, and BMS2055 there were significant differencies of allele frequencies. These results showed a potential application for investigation of putative QTL locations.

• 약학회지
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• 제40권5호
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• pp.550-557
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• 1996

One of therapeutics in liver disease (morbus wilson) is D-penicillamin (D-pen: D-3-mercapto-valin). Especially the cross-linking of collagen molecules could be inhibited by D-pe n in extracellular space. In this study we investigated the antifibrotic effects of D-pen in rats that were induced the liver fibrosis by bile duct ligation and scission (BDL/S). Rats were treated for 4 weeks with D-pen after BDL/S operation or sham operation. The balance between fibrogenesis-marker (PNIIIP) and the fibrolysis-maker (PNIVP) were observed in sera by RIA (radioimmunoassay), and the parameter of collagen deposition in liver tissue (hydroxyproline: HYP) was measured by colorimetry. The weight of liver in BDL/S operated group was increased significantly in compared with sham operation group (15.2g${\pm}$1.1, vs 11.9g${\pm}$3.9: p<0.005, p<0.05). The rats group treated by D-pen showed the lower level of PNIIIP (6.7ng/ml${\pm}$1.5, vs 9.5ng/ml${\pm}$2.8) and the higher value of PIVCP (14.0ng/ml${\pm}$1.9, vs 7.9ng/ml${\pm}$1.5) in sera that compared to untreated rats. The content of HYP was decreased by 141% in BDL/S with D-pen treated group than that of it in BDL/S group. No correlation was revealed between collagen parameters in sera and HYP in liver tissue of BDL/S operated and D-pen treated rats. The group treated with D-pen showed the lower value of clinical biochemistry parameters (GOT: glutamate oxalacetate transaminase, Total-Bilirubin) in compared with only BDL/S operated rats, but the value of GPT (glutamate pyruvate transaminase) and Alkaline phosphatase in two BDL/S groups was nearly same. In the histological finding, we observed mild bile duct proliferation, weak inflammation and fibrosis in BDL/S with D-pen treated group, but BDL/S operated group showed the formation of septum (island of hepatocytes), massive bile duct proliferation. This result represents that the BDL/S operation induces liver fibrosis (cirrhosis) in 4 weeks, and D-pen inhibits the synthesis of collagen weakly and stimulates the degradation of collagen in the extracellular space. We conclude that the monitoring of PNIIIP, PIVCP in sera is useful parameter for screening of antifibrotic effect, and D-pen delay the liver fibrosis.

• 대한화장품학회지
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• 제40권1호
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• pp.89-94
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• 2014

물푸레나무 수피 추출물은 주요 생활성 물질로서 esculetin과 esculin을 포함하고 있다. 이 가운데, Esculetin은 B16F10 melanoma cells에서 $IC_{50}$ value $2.8{\mu}M$의 아주 좋은 melanogenesis 억제 활성을 나타내며, 이를 통해 Melan-A cell에서 melanin 합성을 감소시킨다. 더욱이, esculetin은 mushroom tyrosinase에서도 $IC_{50}$ value $40{\mu}M$의 억제 활성을 나타내어 melanin biosynthesis를 저해한다. 위의 결과들로서, 우리는 melanogenic enzyme 활성 조절에 의해 melanin 생성을 저해하는 효과적인 피부미백 물질로서 esculetin을 제안하고자 한다.

• Journal of Animal Science and Technology
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• 제47권1호
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• pp.49-56
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• 2005

The Korean styled meat products such as grilled and/or roasted ham(Jikhwagui: J), Bulgogi ham(B), Kimbab ham(K) and sliced roasted ham(DDukgalbi: D) were obtained from different Korean meat processing companies and investigated for their salinity, saccharinity, pH, moisture and fat content, meat color and sensory evaluation. The results obtained were as follows; Percentage of saccharinity in J, B, K and D ranged 7.5 %(13) - 12.7% (J2), 5.3 0/«B2) -7.5 o/«BI), 5.2 0/«K4) - 6.6 o/«KI, K2, KS), and 6.60/«04) - 14.4o/«Dl), respectively. Percentage of salinity in J, B, K and D ranged 2.260/«13)- 2.38 0/«J4), 1.850/«B2) - 2.45 0/«B3), 1.94o/«KI) - 2.40% (K3), and 1.830/«02) - 2.19 o/«Dl), respectively. The pH value of J, B and K were ranged 6.30 - 6.44, 6.266.37 and 6.20 - 6.42, respectively, which are slightly higher than that of D(5.86 - 6.25). Content of average moisture were higher in B(61.0 %), K(59.94%) and J(59.63%) compared to the D(55.93%). In crude fat, B and D were ranged 14-21 %, which are very lower than those of K(59.94%) and J(59.63%). In meat color, $L^*$ value were above 50.0, except D2 and D3. $a^*$ value of B were slightly higher than those of other meat products. Compared to sensory evaluation, the overall acceptability of J is excellent in the range of saccharinity 12.7%, salinity 2.3 %, moisture 61 %, crude fat II - 12%, $L^*$ value 52 - 54, and $a^*$ value 12.3- 12.7. In the case of B, the overall acceptability is excellent in the range of saccharinity 6.6 - 7.5 %, salinity 1.90- 2.45 %, moisture 60 %, crude fat 15 %, $L^*$ value 56, and $a^*$ value 15. In the case of K, the overall acceptability is excellent in the range of saccharinity 6.5 %, salinity 2.4 %, moisture 61 %, crude fat 16%, $L^*$ value 53, and $a^*$ valuce 15. In the case of D, the overall acceptability is excellent in the range of saccharinity 14.0%, salinity 2.1 %, moisture 55%, crude fat 55%, $L^*$ value 50, and $a^*$ value 13.